Basic Information

Gene Symbol
Sry-delta
Assembly
GCA_018151105.1
Location
NW:12919214-12920791[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 2.1e-06 0.00013 21.9 0.9 2 23 183 205 182 205 0.95
2 7 0.00087 0.053 13.7 0.1 1 23 211 233 211 233 0.96
3 7 6.7e-07 4.1e-05 23.5 1.5 2 23 240 261 239 261 0.98
4 7 5.1e-05 0.0031 17.6 1.4 1 23 267 289 267 289 0.98
5 7 0.00023 0.014 15.5 2.2 3 23 298 318 296 318 0.96
6 7 1.8e-06 0.00011 22.1 3.8 1 23 325 347 325 347 0.98
7 7 0.0015 0.089 13.0 2.2 3 23 395 416 394 416 0.94

Sequence Information

Coding Sequence
ATGGATACGTGCTTCTTTTGTGGCGCCGTGGACGTAGAGGAAGACGCCAGCGTCAGCTATGAGAAACTTTCTGCGAAAGTGCCGTCGTCACAGAAGACAATTTCGGTGGTGCTGAACCATCTTGCCAACTGCATAAACACAAGTCTCAAATTGCCAGTAAACTCAAAACTTTGCCCCCGGTGTTTCAACGAGCTGGCTGATTACGATACCATAATGGTTAACTTAATGACCACACAGAAGCGTCTGACGAACCAGTTGAAGACAGCACTAAAGTCAGAGTTTGAAAGTCCTGAGCCCTCGGAGGATTTGGTGGTGGAAGAAGCGCCACTGGAGGATGCCGACAACGACGCCGATGCTGTGGCCGACGCATTGTTTGTGGAACTTGTGAAGGACCAAGAAGATTCTGATGCAGAGATTAAGCAGGAGtacgacgatgacgaggaggaggaggaattCGTTTGCGAAGTCGACGTGGGGGAGTCGGAGGGTGGCATGCATGAAAGATCCGAGCTGGATGATAAGCCACCCAAGAAACGCACCAAGCAGGAGTGCAGCCACTGTGGAAAAGTTTACAATTCGTGGTACCAAATGCAAAAGCACATCAATGAAGACCACTCGACAACGCAGAATCACATCTGTCCCATATGTGGTGTCATACGCCGAGATGAGGAATATCTGGAGTTGCATATGAACTTGCATGAGGGCAAGACCGAGAAGCAATGTCGCTATTGCCCGAAGAGCTTCTCCAGGCCCGTCAACACTCTGAGGCACATGCGCATGCACTGGGACAAGAAGAAATATCAGTGTGAGAAGTGCGGACTGCGCTTCTCCCAGGACAACTTGCTCTACAACCATCGTCTCCGCCACGAAGCCGAGGAAAATCCCATAATCTGCAGCATTTGCAATGTGTCCTTCAAGTCGCGCAAGACATTCAACCACCACACGCTTATACACAAAGAAAACAGACCCCGTCACTACTGCTCTGTTTGCCCCAAGTCGTTCACTGAACGCTATACCCTCAAAATGCACATGAAGACCCACGAAGGCGATGTTGTCTATGGGGTCAGAGAGGACGCTCCGTCAGACGACCAGCAAGTGGTGGAGGAGCTTCATGTGGATGTGGACGAATCGGAGCAGGCTGTGACTGTCATCATGTCGGACAATGACGAAAACAGTGGATTCTGTTTGATCTGCAACACCAActttgaaaacaaaaaggagCTCGAGCACCACTTACAATTTGATCACGATGTCGTCCTAAAATAG
Protein Sequence
MDTCFFCGAVDVEEDASVSYEKLSAKVPSSQKTISVVLNHLANCINTSLKLPVNSKLCPRCFNELADYDTIMVNLMTTQKRLTNQLKTALKSEFESPEPSEDLVVEEAPLEDADNDADAVADALFVELVKDQEDSDAEIKQEYDDDEEEEEFVCEVDVGESEGGMHERSELDDKPPKKRTKQECSHCGKVYNSWYQMQKHINEDHSTTQNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREDAPSDDQQVVEELHVDVDESEQAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQFDHDVVLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00517921;
80% Identity
-