Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:2150586-2153349[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.084 5.1 7.5 0.1 3 23 291 312 290 312 0.91

2 10 6.4e-05 0.0039 17.3 0.5 6 23 321 338 321 338 0.99

3 10 1.7e-05 0.001 19.1 0.3 1 23 344 367 344 367 0.98

4 10 0.00014 0.0086 16.2 0.7 1 23 379 401 379 401 0.97

5 10 0.00097 0.059 13.5 7.1 1 23 408 431 408 431 0.96

6 10 3.4e-06 0.00021 21.3 2.4 1 23 437 459 437 459 0.97

7 10 0.064 3.9 7.8 0.7 2 23 468 489 467 489 0.97

8 10 0.00015 0.0094 16.1 3.1 3 23 496 517 494 517 0.95

9 10 1.3e-06 7.8e-05 22.6 1.1 1 23 523 545 523 545 0.98

10 10 0.00017 0.011 15.9 4.4 1 23 551 574 551 574 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.084	5.1	7.5	0.1	3	23	291	312	290	312	0.91
2	10	6.4e-05	0.0039	17.3	0.5	6	23	321	338	321	338	0.99
3	10	1.7e-05	0.001	19.1	0.3	1	23	344	367	344	367	0.98
4	10	0.00014	0.0086	16.2	0.7	1	23	379	401	379	401	0.97
5	10	0.00097	0.059	13.5	7.1	1	23	408	431	408	431	0.96
6	10	3.4e-06	0.00021	21.3	2.4	1	23	437	459	437	459	0.97
7	10	0.064	3.9	7.8	0.7	2	23	468	489	467	489	0.97
8	10	0.00015	0.0094	16.1	3.1	3	23	496	517	494	517	0.95
9	10	1.3e-06	7.8e-05	22.6	1.1	1	23	523	545	523	545	0.98
10	10	0.00017	0.011	15.9	4.4	1	23	551	574	551	574	0.96

Sequence Information

Coding Sequence: ATGATTTGCAGATTATGCCTGCGCAGCATAAATCCCAGCAATGCCGTATTCCTGTTCGAAACGAACGAGACGATGGCGGAGACGATTCTGGTCAAGATGATTGCCAAATTCCTGCAACTGGAGATCACGCCCGACGACAGCATCTCGACGAGCGTCTGCACCGAATGCTGTGAGCATCTGGAGGACTTCAACACCTTCTGGCAGCTGGTGGAACAGAAGCAGGGAACTCTCAAAAAGGAGTTTCTCACCGTCGACGTGGACTGCGTGGCGATGAAGTGGACGGGCGAGGTGGATGTGGACGTCAACATTGACGAGCTGCCGCTGGTGGCAGTCGAAATGGACGAGAAGCCTCTCGATATGCACAACCTCAGCATGCTGGGCAGTGTTctggatgtgaatgtggacAGTGTGGAGGTGCCACAGGCACCGCCAGTGGATATCAAAATTCAGCAGACCGATTACTTGTCCGAGGAAGACGAACATCCGCCCCATCTCGATGCGACTGATGACAGTGAGTTCGAGTGCGAGGCAGGCCCCCAAGAAGACACCTCGGATGATGAGCCGCTGGTCAAGCTGCAGGACAAGCTGAAGCCCAAGCGCAAGTCTCACGTCCGCGCCACCAAGACACTGGAAGACAGCTGCTCACTCGGAGGTCAGGAGCTGAATTATCTGCTTGGACGgggcgatggcgatggtgaAGGCGAGGGCAGCAAAGGGCGTCGCAAAAAGGCGCCCGGCCAGCGGAGCCTACCCACGGAGGTGCAGGAAAGCGAACTGCAGGCAGCGCTCGAACGCAAGCCCAAGGGCTGCTCGCGGGCCCAGCTGGCCAAGCGGTACGAGGAAGTCATTGCCAGCTACATGAACGCCGACTGCGACCTGTGCGACTTCAGCGCCAAGTATCTGTCCGAGCTGAAGGTGCACTTTCTGGAGGTCCACCAGCGCGAGTTCTACATAAAGTGCTGCAACAAGGTCTTCACACGCGCCTCCAAACTGATGGATCACATACGCAAGCACGTTAATCCGAAGCTCTTTACCTGCTCCATCTGCCAGAAGACGCTCAATTCGCAGGACTATCTGGCCACCCACATCGAGACGGTGCACAATAAGGTGGAGAAAATCGACAAGGTGCTGCAGTTTCCCTGCTCCAAGTGCGAGCGCACTTTCAGCAGTGAGCGACGACTGGCCAATCATCTCGCCAAGCATGACACGGCGACGCTGGAGCACATCTGCCACATATGccataaaaaTTTTGCCAATGTCCATCGGCTGCGCCGGCACATCCAGTCCATACACGAGGATCTGCACCGGCATGTGTGCGACATCTGCGGCAAGAAGTTCAAATTCAAGCCCTCGTTCGAGCGGCATCTGCGCGAGCACCAGGGCGTGGTGGCACCGGCCATGCAGTGCCCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGTCTGCGGCTGCATCGCTTCACGCACGACAGCACCAACACGGACTGTCCCCACTGCTCGAAGACATGCAACTCGAGAACGGCGCTGCGCGCCCACATCAAGTATGCCCACAAGCTGACGACCAGCTTCCAGTGCACATACTGCGAGAAGACCTTTAAGCAGCAGCGCAACCTGGACGAGCATCTGGCCATCCACACGGGCCTCCAGCTCTACAACTGTCCGCACTGCCCCAAGGAGTGCCGCTCCCGGTCCAACATGTACGTGCACATCAAGCAGCGGCATGCGGAGGAGTGGCTCACCGCCAAGATGGCCCGCTCCCACAATCCGCAGTTCAAGCCGCACACCTAA
Protein Sequence: MICRLCLRSINPSNAVFLFETNETMAETILVKMIAKFLQLEITPDDSISTSVCTECCEHLEDFNTFWQLVEQKQGTLKKEFLTVDVDCVAMKWTGEVDVDVNIDELPLVAVEMDEKPLDMHNLSMLGSVLDVNVDSVEVPQAPPVDIKIQQTDYLSEEDEHPPHLDATDDSEFECEAGPQEDTSDDEPLVKLQDKLKPKRKSHVRATKTLEDSCSLGGQELNYLLGRGDGDGEGEGSKGRRKKAPGQRSLPTEVQESELQAALERKPKGCSRAQLAKRYEEVIASYMNADCDLCDFSAKYLSELKVHFLEVHQREFYIKCCNKVFTRASKLMDHIRKHVNPKLFTCSICQKTLNSQDYLATHIETVHNKVEKIDKVLQFPCSKCERTFSSERRLANHLAKHDTATLEHICHICHKNFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFERHLREHQGVVAPAMQCPVCGVWLKNEHSLRLHRFTHDSTNTDCPHCSKTCNSRTALRAHIKYAHKLTTSFQCTYCEKTFKQQRNLDEHLAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHAEEWLTAKMARSHNPQFKPHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474705;
90% Identity: iTF_00580951;
80% Identity: -