Basic Information

Insect: Drosophila obscura
Gene Symbol: Gzf1
Assembly: GCA_018151105.1
Location: NW:2903887-2907510[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0015 0.092 12.9 2.7 1 23 211 234 211 234 0.97

2 12 2.1e-06 0.00013 21.9 5.1 1 23 239 262 239 262 0.97

3 12 2.7e-05 0.0017 18.4 3.2 1 23 267 289 267 289 0.98

4 12 3.8 2.3e+02 2.3 3.9 2 23 296 319 295 319 0.91

5 12 0.0006 0.037 14.2 3.9 3 23 330 351 329 351 0.95

6 12 0.0036 0.22 11.8 0.2 1 23 357 380 357 380 0.96

7 12 0.0081 0.5 10.6 0.3 2 23 391 413 390 413 0.95

8 12 0.0011 0.065 13.4 0.4 1 23 442 464 442 464 0.97

9 12 8e-06 0.00049 20.1 4.0 1 23 471 493 471 493 0.97

10 12 0.00022 0.014 15.6 0.1 2 23 500 521 500 521 0.97

11 12 0.00014 0.0084 16.2 1.1 1 23 528 550 528 550 0.99

12 12 0.00013 0.008 16.3 3.7 1 23 556 579 556 579 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0015	0.092	12.9	2.7	1	23	211	234	211	234	0.97
2	12	2.1e-06	0.00013	21.9	5.1	1	23	239	262	239	262	0.97
3	12	2.7e-05	0.0017	18.4	3.2	1	23	267	289	267	289	0.98
4	12	3.8	2.3e+02	2.3	3.9	2	23	296	319	295	319	0.91
5	12	0.0006	0.037	14.2	3.9	3	23	330	351	329	351	0.95
6	12	0.0036	0.22	11.8	0.2	1	23	357	380	357	380	0.96
7	12	0.0081	0.5	10.6	0.3	2	23	391	413	390	413	0.95
8	12	0.0011	0.065	13.4	0.4	1	23	442	464	442	464	0.97
9	12	8e-06	0.00049	20.1	4.0	1	23	471	493	471	493	0.97
10	12	0.00022	0.014	15.6	0.1	2	23	500	521	500	521	0.97
11	12	0.00014	0.0084	16.2	1.1	1	23	528	550	528	550	0.99
12	12	0.00013	0.008	16.3	3.7	1	23	556	579	556	579	0.98

Sequence Information

Coding Sequence: atgGAAACGTGTCGCACCTGTGCGATTTCCATGTTTGTTTGCGATTTCGAAaatggcagcaacaattttttggatCTCTTCCATCCCACATGCTGGCAGAGTGAAATGGCCCAAATACGACTGGAGTTTGTCCACTGGAATCTGAAGATTTCCCCCAATGATGGACTGCCACAGAAAATATGCAGCGACTGTTTTACCAAGTTCTGCTCCATCTACACATTTCGACTGGGCTGCCAGGAGGCGCAGCTAAAGTTGTCGAACATCTATGACAAAATCGATGCCAGCAGCTTGGAGGATGACAACCATGCAGAGGAAGAAGCGGATGCTGCgccagaaacagcaacaattatAGGAACGACAACATCAACAACGACGGTTTCAACCGAAACACAACCaaacactgccactgcccccccAATAGAATTTTTTGTGGAAACCATAGGCCACAACGAGGCAGACAACGACGAATCACAGCCACCATAcctggatgatgatgatgatgataatgaggcCACTCAGGAACTGACCATTAGCTATGCCTGTAAGTACTGCTTCAAGCCGCAGGAGAGctaccagctgcagcagctgctcctggaGCACATCAATGCCAGCCACGATCCAGATCAGCCGTACAACTGTCCGGAGTGTAAGGAGTGCTTTCAGGATGCAGCCTCCCGGACCGTGCACATCAAGAGCTGTCATGTGGAGAAGCAGTTCAAGTGCGAGGTGTGCGGCAAGAAGTACAGCGATCGCCACAATCTGCGCCACCACATCGAGAAGTATCACTCGGAGACGGACTTTGAGTGCACCATGTGTGAGAAGCGCTTCTTCACACGCAAGAGTCTCAACTATCATATGAAATGGCACAATCCGGAGCGGCAGCTCAAGTGCCGCCAGACCGGCTGCGAGCGTTTGTTCATCAATCAGCGGCACCTCAAATGCCACGAAGCCACCCATACGGGCGCCAGTGCCAGAAAGAGCGAGCACTGTGGCTTCTGTGGTAAAACTTTCATACACCTAAAGACACTACGATGGCACATCTATAGACAGCATGGTGGGGAGAAGCCCTACAAATGTGCCAACTGTACGGAGGTATTCGCCTCGTATGCAGAGAAAAGGATACACATGCTGGAGCGGCACAGGGAGAATCTAACGCCCATTGAGCGTAGCGAGTGCATGTTGTGCCGCCAGCCCTTTGGCACCGAGCAGGATCTCATACATCACATGTCCGTGGATCATTTGCAGCGTGCGGCCAGTGTGCCAGTTATAGCCAACAACAAGCGTGTGCTGCAGCAGAAGCGGGAGCGTCAGTATTCGGGACTCTTTCAGTGCGACAGCTGCACCCAGAGATTCAATATGAAGTCGGCCCTGGATCGACATGCCGCCGTGCACTCGGAGAAGGACAGGCCGCATGCCTGTCCACATTGCTCCAAGCGTTTCAAAAGGGCCCAGGACATGAAGTGGCATATCAAGACGCACGAGAAGGAGAAGCCCAatgtgtgtgatgtgtgtggCAAGGCCTTTGCCTTGAAGTATGTCCTCACACAGCATAGGCTCAGCCATGAAGTTTTGGAGAAGAACTTTCAATGCAACATTTGCGGCCGATCCTATCTATTTGAAAAGTCTCTGCGGCTGCATCAACGCGTCCACACGGGCAACACCTACTACAAATGCGATCTGTGCCAGGAACGCTTCGTAACGCACATTAAGTTGAAAACTCATATGCAGAAGACGCATGCACATGCCTCTGAGACGCCTTCACCGGACTCCCTGGATGATTTGATAAACATTGTGATTTCTTAA
Protein Sequence: METCRTCAISMFVCDFENGSNNFLDLFHPTCWQSEMAQIRLEFVHWNLKISPNDGLPQKICSDCFTKFCSIYTFRLGCQEAQLKLSNIYDKIDASSLEDDNHAEEEADAAPETATIIGTTTSTTTVSTETQPNTATAPPIEFFVETIGHNEADNDESQPPYLDDDDDDNEATQELTISYACKYCFKPQESYQLQQLLLEHINASHDPDQPYNCPECKECFQDAASRTVHIKSCHVEKQFKCEVCGKKYSDRHNLRHHIEKYHSETDFECTMCEKRFFTRKSLNYHMKWHNPERQLKCRQTGCERLFINQRHLKCHEATHTGASARKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTPIERSECMLCRQPFGTEQDLIHHMSVDHLQRAASVPVIANNKRVLQQKRERQYSGLFQCDSCTQRFNMKSALDRHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFQCNICGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKLKTHMQKTHAHASETPSPDSLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00473982;
90% Identity: iTF_00575023;
80% Identity: -