Basic Information

Insect: Drosophila obscura
Gene Symbol: Znf526
Assembly: GCA_018151105.1
Location: NW:527708-529482[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00016 0.0096 16.0 0.7 3 23 92 112 90 112 0.97

2 7 1.9e-07 1.2e-05 25.2 0.8 1 23 126 148 126 148 0.99

3 7 2e-08 1.2e-06 28.3 0.9 1 23 154 177 154 177 0.98

4 7 6.6e-05 0.004 17.2 2.4 1 23 183 207 183 207 0.97

5 7 6.6e-06 0.0004 20.4 0.8 2 23 214 235 213 235 0.96

6 7 7.3e-05 0.0045 17.1 5.5 1 23 241 263 241 263 0.97

7 7 2.2e-06 0.00014 21.9 1.7 1 21 269 289 269 293 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00016	0.0096	16.0	0.7	3	23	92	112	90	112	0.97
2	7	1.9e-07	1.2e-05	25.2	0.8	1	23	126	148	126	148	0.99
3	7	2e-08	1.2e-06	28.3	0.9	1	23	154	177	154	177	0.98
4	7	6.6e-05	0.004	17.2	2.4	1	23	183	207	183	207	0.97
5	7	6.6e-06	0.0004	20.4	0.8	2	23	214	235	213	235	0.96
6	7	7.3e-05	0.0045	17.1	5.5	1	23	241	263	241	263	0.97
7	7	2.2e-06	0.00014	21.9	1.7	1	21	269	289	269	293	0.92

Sequence Information

Coding Sequence: ATGGCAATTAAAACGCTGGAGGAGGCCAGCATCGACTGGGACTCACTGATAGAAGAGTGCGAGGAGTCCGAAGACTCCGACCAGGAGTGGGTCAACTCGATAATAGTGGAAGAACCAGAAGAGGAGTTGGCAGAAATTACGGTAGATCAGGACGAAGCAGAGCAGGCTGTGGATGACCCCGAAGAGTGGATGATGGGGCTGGAGGAGGAAGAATTAGAGCCCGGAGAGTGGAGACCAGATCCTACGGATTCAACGTACCGCCTGCCCTGGGCCTGCACACGCTGCCCCATGCGGTTCGCCAGTCACGAGAAGCTTATCGCCCACCGGCGCATGCATCCTCGAACGCGAAGGGAAAACTGTCCGCCGTCGTCTACCTTCACGTGCGAGGAGTGCGGCAAGGAGTTCAAACGCCGCCGCTGGCTCGACGAGCATCTGCGCACCCACACCGGCGACCGGCCGTACGAGTGCCACGATTGCGGTGCCCGTTTCGCTCAGAACAGCAACCTTAGCGTTCACATCCGGACCAAGCACCTTAAGGAGGCTAAGCATCAGTGCCCCAAATGCCCCGGCCGTCGTTTCACACGCCGGCGACTGCTCCAGCAGCACCTGAAGACGGTGCACCAAAAGCTGTTCGATCTGTCGTGCGAACAGTGCAGCGCCAGCTTCTCGCACCCAGTCTACCTCAAGAAGCACATGCTGGTCCATGGCTGCATCAAAGCCTACTGCTGTCACATTTGTGGCAAAAAGTTTAGCCGGCTCGAGAACCGAAACTCTCACCTCTTCGTCCACAGCACCCGTAAGCCCTACATCTGCACTGTGTGCGGCACGGGCTTCTCAAGAAAATCGCATCTGCTGCAGCACATACAGTTCAAGCAGCACCCCAACGAGGTGatccagcggcagcagccatACTTCAGCGACTTGCTCAGCCAGTTCACCCGCAAGAAGGATGCCGAGGAGCATATTGATGGAGAATTTCCATTGAATTGCAATTAA
Protein Sequence: MAIKTLEEASIDWDSLIEECEESEDSDQEWVNSIIVEEPEEELAEITVDQDEAEQAVDDPEEWMMGLEEEELEPGEWRPDPTDSTYRLPWACTRCPMRFASHEKLIAHRRMHPRTRRENCPPSSTFTCEECGKEFKRRRWLDEHLRTHTGDRPYECHDCGARFAQNSNLSVHIRTKHLKEAKHQCPKCPGRRFTRRRLLQQHLKTVHQKLFDLSCEQCSASFSHPVYLKKHMLVHGCIKAYCCHICGKKFSRLENRNSHLFVHSTRKPYICTVCGTGFSRKSHLLQHIQFKQHPNEVIQRQQPYFSDLLSQFTRKKDAEEHIDGEFPLNCN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601209;
90% Identity: iTF_00474657;
80% Identity: -