Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:2012745-2015066[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.3e-06 0.00039 20.4 0.0 1 23 221 244 221 244 0.96

2 8 2.5e-05 0.0016 18.5 2.4 2 23 266 288 265 288 0.94

3 8 6.5e-05 0.004 17.2 0.5 2 23 313 333 313 333 0.96

4 8 2.4e-06 0.00015 21.7 1.8 1 23 339 361 339 361 0.99

5 8 4.1e-06 0.00025 21.0 2.0 2 23 368 389 367 389 0.97

6 8 4e-08 2.4e-06 27.4 0.8 1 23 395 417 395 417 0.98

7 8 0.0013 0.081 13.1 0.2 1 22 423 444 423 447 0.91

8 8 0.00049 0.03 14.5 1.0 1 22 519 540 519 543 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.3e-06	0.00039	20.4	0.0	1	23	221	244	221	244	0.96
2	8	2.5e-05	0.0016	18.5	2.4	2	23	266	288	265	288	0.94
3	8	6.5e-05	0.004	17.2	0.5	2	23	313	333	313	333	0.96
4	8	2.4e-06	0.00015	21.7	1.8	1	23	339	361	339	361	0.99
5	8	4.1e-06	0.00025	21.0	2.0	2	23	368	389	367	389	0.97
6	8	4e-08	2.4e-06	27.4	0.8	1	23	395	417	395	417	0.98
7	8	0.0013	0.081	13.1	0.2	1	22	423	444	423	447	0.91
8	8	0.00049	0.03	14.5	1.0	1	22	519	540	519	543	0.91

Sequence Information

Coding Sequence: ATGTATAATATAATGCCGAATCAAGTTATTAATATTAACCATCTAAGCTGCCGCGTCTGTCTGGAGACAAACGAGGGCGCCTTGCGTCTGCACGACGAGATCCAGTACAATGAGCTCAACTTTGAATTGTGGCAACTGCTGGAAATCGTCTCCAAAGTAAAGTGCACCTGGAACGAGGCAGATATGCCGACCCGTTTGTGCCAGAATTGCACACGCCGCTTGATAGCCGCCTATGAGTTTATTCTCGATGTGGAGAATGCACAGCACACGCTGCAGAACTTGTACCTTGTGATGAAGGAACCGGAGGAGACGACCCATGTGGAGGTTCTGGAACTGTGCAGCCAGGACGAGTTTTTGCCCGTCATCTGTGACACTGTGGAGGTGGCTGTGACGATGGAAGCAGAGGACGCTGCTGAAGCTGTGGTCGATGTGCCCGTGCCCTTTTCACAAGCAGAAACGATTATCGAGCCAATTTACAAAACAGAGCATCTAGGAGAGTTGGAGACTGAAATACCATTAGAGGCAGAAGACTTGGATGCTGCACAAAATGTGGATGACAAAAATACGGATGTGAAAGAGGAGAAAGAGGAAGCTGCCTCTGCGACAAAGCCGCGTCCCTCTCAGCTGGGCAGTCGGCTGACCCACTCACAGAATTTCATCTTTAAGTGTGCCATTTGTCCGCGTGCCTTTGCCAAAAATGATTCGCTGGCACGGCACATCGCCGTTGCCCACAGTCAGACCGCGGACGTGGCCGCCCAGGAGCTGGCAAACGAGAGCAGTGGAAGCGGCGTGCTCACCTGCAAGCACTGTCCACGCATTTTGAAGCGGCAGGACACACTGCGTCGTCACATGCAGGCATTCCATCCAGAGGAAGCGGCCAAAGATGATACTGAGTCAACTGCCAGCTCGCAGCGGAAGCGCACGGCCAAGCGTCGTGAGTGCCCCCACTGTGGCATTAGTTTTCCCACCTCCAGCCTGACCATCCACATACGTCGGCACACTGGCGAGTATCCGTACAAATGCGAGCAGTGCGAGAAGGCCTTTCCGCGCAGCCAGGACCTAAGCTTGCATATGCGACACCACACGGGCGAAAGACCCAGCGAATGCAAAATCTGCTCAAAGAAATTCATATCCCAGAACAAGCTGTCCAGACACATGCGCCTACACACAGGCCAGCGTCCGTATGCCTGCGACAAGTGTGACAAGAGTTTCGTGCAATCCAACGACCTGAAGATCCACATGCGACGTCACACGGGCGAGCGGCCCTACAAGTGTGATGTATGCGGGGATAGCTTTGTCTCTGGCTCCCTACTGAACGTCCATCGTAATCAGAAAGGTCACCACATGGCAACATCTGGAAACCTGAGCTCCGGTGATACCACTGACGATCCGTATGTAAATGCGCGTGTCAACATGCGTCGAGCGGAGGATATTGAACGTATGCGGCTGAAGCGAGATTCCGAGGATCGACTTAACCAGCCCCAGGCGTCGCCATCAGAGCCGCAGCCACCGTCGCCAAAACAGTATTCCCCTCCGGAGAAGCCGCTCCTGATCTACAAGTGTGGCGTCTGTGACTGGACCTTCAAGAGCGGCGCCTGTCTAACCATTCATCGCAACAACATGTCCCACTACGAGATCGGCAAGGTCGACTACGGTGATCCCTTTTCCAAGATGGTCAAAAGgcataattaa
Protein Sequence: MYNIMPNQVININHLSCRVCLETNEGALRLHDEIQYNELNFELWQLLEIVSKVKCTWNEADMPTRLCQNCTRRLIAAYEFILDVENAQHTLQNLYLVMKEPEETTHVEVLELCSQDEFLPVICDTVEVAVTMEAEDAAEAVVDVPVPFSQAETIIEPIYKTEHLGELETEIPLEAEDLDAAQNVDDKNTDVKEEKEEAASATKPRPSQLGSRLTHSQNFIFKCAICPRAFAKNDSLARHIAVAHSQTADVAAQELANESSGSGVLTCKHCPRILKRQDTLRRHMQAFHPEEAAKDDTESTASSQRKRTAKRRECPHCGISFPTSSLTIHIRRHTGEYPYKCEQCEKAFPRSQDLSLHMRHHTGERPSECKICSKKFISQNKLSRHMRLHTGQRPYACDKCDKSFVQSNDLKIHMRRHTGERPYKCDVCGDSFVSGSLLNVHRNQKGHHMATSGNLSSGDTTDDPYVNARVNMRRAEDIERMRLKRDSEDRLNQPQASPSEPQPPSPKQYSPPEKPLLIYKCGVCDWTFKSGACLTIHRNNMSHYEIGKVDYGDPFSKMVKRHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517881;
90% Identity: iTF_00474655;
80% Identity: -