Dobs011249.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila obscura
Gene Symbol
-
Assembly
GCA_018151105.1
Location
NW:2892919-2896668[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 5.3e-05 0.0033 17.5 0.1 2 23 218 239 217 239 0.97
2 11 1.2e-07 7.6e-06 25.8 0.1 1 23 245 267 245 267 0.98
3 11 8.9e-06 0.00054 20.0 2.3 1 23 273 295 273 295 0.99
4 11 1.8e-06 0.00011 22.2 1.0 1 23 301 323 301 323 0.97
5 11 0.00079 0.048 13.8 1.6 5 22 333 350 329 353 0.83
6 11 0.23 14 6.1 4.0 2 23 682 703 682 703 0.98
7 11 0.0085 0.52 10.6 0.9 1 21 709 729 709 730 0.94
8 11 0.02 1.2 9.4 0.0 8 23 768 783 767 783 0.96
9 11 8.9e-06 0.00054 20.0 2.3 1 23 789 811 789 811 0.99
10 11 1.8e-06 0.00011 22.2 1.0 1 23 817 839 817 839 0.97
11 11 0.0011 0.067 13.4 0.7 5 23 849 869 845 869 0.84

Sequence Information

Coding Sequence
ATGCCCGAATACATGCTTTGTAGGATCTGTTTAACAGAAGATTTAAGTTCGGACGGAATGACACCACTTTTCGACGAGCAGAACGTCGAGTGTCCAGAGCTCGTGAGAAAAATTGAAGAAATCGGCAGCATCAAGCTAGCCCCACTTCAGGACATGGTAAGCATGCTTTGCTTTAATTGCGTCGACACCCTTACTATTGCACATAAATTCCGAGAACTGTGCCAGGCCAGCGAGCAAGCCTTTTCCGATAATATTGTCAAGGCGGAGATGAAATGCGAGCCTACAGACGATCCTCCGAGCATGGAAGAGCATCACATTGAATATATATACGAGGCAGCCAGCGAATTTATTGATGCCGATGGGGATATTGAACTAGACACCATGCTGGAAGAGCGTTTGGAGGATGGAATCGCAGAAGCTGAAGCGACATATGGCGACATGAATGTGGTGGAGGAGGTCGATGATAATGACCTGCTGTTAGAAAACGCTAGCGATAGTGACTACGAACCCAGTGAACGTTTCCGAAAGCCCAAGATTCGTAAAACACGGCTAGCCAAACGTGGTCGTGGCCGACCACGGAACTCCACAGCAGAAAATGGTCAGGAAAAAGCGCCCGGTGTGTGCAGGTCCAATGAAGAGCCCACAAATATCATGTGCGAAATATGTGGCAACATCTACTCCAAGAGAGCAGCCCTCAACATTCACATGCGCCGTCACCTGGCTGAGAAGCCTTTCGAATGCGAGATCTGCAGCAAAACGTTTGCGGGTCCCTCGGAACTAAATCGCCATATAAGAGTGCATACGGGCGAGAAACCGTTCACGTGTAAATACTGCTCCCGTTCGTTTGCAGATCGAAGCTCCAACATACGGCATGAAAGAACTCATACAAATGAACGGCCCTTTGCCTGCTCAACATGTGGCAAGTCCTTCTCCTATTCTAATGTCCTGAAGAACCACATGTTAACTCACACGGGGGAGAAGCCTTTCTTgTGTCTGCCGTGtaataaaacattttcccGTAAGCACCAGCTGGAGCAACACATCGGCACAATGACCCACCAGCAAACTATGAGAGCGCATCAGACAAATGAGGCGTTACGGGGGACTTCGGAATTATACTAcataaaaatgccGTTTACATGTCGAGGTTGTGGGGGTGACATTTTTAATACTACAGCCAAGAATATATTCCACATGGAGAACGAGCAGATGCTTTCGAACCTCCAAGCAGTGAGCGGGATCTCGTTCATGTATGATCCCGACCTGCCAAGCTGCCTATGctcgttttgtttgttcgACTTGAATCAGGCAGTCGTGTTCCGAAATCGCGTTCGGGCTCAGGCGGACtttctgctgcagcagcaacttcCCAGCAGGTCCACGACTCCGTCCGAAATGCCAGTATGCTACATACCAGATAGTGACGAGGAGAATGAGCAAGCACAAGCCGTTGATGGTTTGGATAATGAACAGGACGTGTCGACGGATGATGTTAATGTTTCCCATGATGAAAACGAAGACTTGTTTAAGGGATTCCCAGAATCCGATCAGGATTCCGACACCCATTCCCCGGCTCCGAGTATGCAAGGAGAAGAGCTGGACGAAAACCAGGCACTATCAATCCACATACTAGATAGTGACGAGGAGAATGAGCAAGAAGAAATAACCGCCGCCGACAACATGGTTACGGATATGCTAGAGGAGCTGGAAGCAAATGGGTCCGACGACCAAACACCTGATGCGGCACAGGATGATGACTCTCTGATGGCGAGTCTGGAAAAGGGGTTGGCAGGAAGATCTGATTTCGACGAAACTGATGCTGCCGAGACACCGCAAGTTGCTGCGTTGCTGATTGCGAGTCTGCAGAAGGATTTAGGATATGCTAATGCTGGCAGTGATACCGAAAATATCATCGAGACGCCGAAACGCTCTAACAAAAAGCCTAACCCCAATCTTCCAACTTCTAAGAATGTTAATAAGCCCAATCCTTTGCCCGCTAACAGCGTTGGCAAGCAACGCTGTTTGGCAGAGAAGAAGATGGCTAAATGCGGAGTTTGCAGCAGGATGCTTGGTTCTTCCCATGCGTTAAAGTGCCATATGCGAACACACACGGGCGAGCGACCATACATGTGTCAGCACTGTTCTAAACAATTTGTGACTGGAGGCAATAAAACCCGTCATGAAagAATTTGCCTCGGCCAAACTACAACGGACCCAACGGACACGGCCAAGACACCATTACAGTGCCAGCGCTATTTGCATTACTATTCGTCTTTAGCCAACAAAAACCGTAATGAAagCAAAACGTTTGCGGGTCCCTCGGAACTAAGTCGCCATATACGAGTGCACACGGCCGAGAAACCGTTCACGTGTAAATACTGCTCCCGTTCGTTTGCAGATCGAAGCTCCAACATACGGCATGAAAGAACTCATACAAATGAACGGCCCTTTGCCTGCTCAACATGTGGCAAGTCCTTCTCCTATTCTAATGTCCTGAAGAACCACATGTTAACTCACACGGAGGAGATGGCTTTCTTgTGTCTGCCGTGTAATAAAACCTTTCCCCGTAAGCACCAGCTGGAGCAACATCTTGCCACAATAGCCCACCAGCAAGCTGTGAAAGCGCCCAAACCGATACGAAATAGGCGATATACCACGCGTATATGA
Protein Sequence
MPEYMLCRICLTEDLSSDGMTPLFDEQNVECPELVRKIEEIGSIKLAPLQDMVSMLCFNCVDTLTIAHKFRELCQASEQAFSDNIVKAEMKCEPTDDPPSMEEHHIEYIYEAASEFIDADGDIELDTMLEERLEDGIAEAEATYGDMNVVEEVDDNDLLLENASDSDYEPSERFRKPKIRKTRLAKRGRGRPRNSTAENGQEKAPGVCRSNEEPTNIMCEICGNIYSKRAALNIHMRRHLAEKPFECEICSKTFAGPSELNRHIRVHTGEKPFTCKYCSRSFADRSSNIRHERTHTNERPFACSTCGKSFSYSNVLKNHMLTHTGEKPFLCLPCNKTFSRKHQLEQHIGTMTHQQTMRAHQTNEALRGTSELYYIKMPFTCRGCGGDIFNTTAKNIFHMENEQMLSNLQAVSGISFMYDPDLPSCLCSFCLFDLNQAVVFRNRVRAQADFLLQQQLPSRSTTPSEMPVCYIPDSDEENEQAQAVDGLDNEQDVSTDDVNVSHDENEDLFKGFPESDQDSDTHSPAPSMQGEELDENQALSIHILDSDEENEQEEITAADNMVTDMLEELEANGSDDQTPDAAQDDDSLMASLEKGLAGRSDFDETDAAETPQVAALLIASLQKDLGYANAGSDTENIIETPKRSNKKPNPNLPTSKNVNKPNPLPANSVGKQRCLAEKKMAKCGVCSRMLGSSHALKCHMRTHTGERPYMCQHCSKQFVTGGNKTRHERICLGQTTTDPTDTAKTPLQCQRYLHYYSSLANKNRNESKTFAGPSELSRHIRVHTAEKPFTCKYCSRSFADRSSNIRHERTHTNERPFACSTCGKSFSYSNVLKNHMLTHTEEMAFLCLPCNKTFPRKHQLEQHLATIAHQQAVKAPKPIRNRRYTTRI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-