Dobs001439.1
Basic Information
- Insect
- Drosophila obscura
- Gene Symbol
- -
- Assembly
- GCA_018151105.1
- Location
- NW:458957-462376[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 5.1 3.1e+02 1.8 0.9 2 23 127 149 126 149 0.92 2 13 0.0047 0.29 11.4 4.3 2 23 176 198 175 198 0.95 3 13 6.4e-05 0.0039 17.3 3.1 2 23 205 227 204 227 0.96 4 13 0.01 0.63 10.3 9.1 2 23 477 498 477 498 0.97 5 13 1.2e-06 7.1e-05 22.7 1.2 1 23 504 527 504 527 0.96 6 13 0.0006 0.037 14.2 0.3 1 23 532 555 532 555 0.93 7 13 5.8e-05 0.0036 17.4 5.5 1 23 573 595 573 595 0.96 8 13 0.00098 0.06 13.5 1.1 1 23 600 622 600 622 0.97 9 13 3.1e-05 0.0019 18.3 1.7 1 23 628 650 628 650 0.95 10 13 2.2e-05 0.0013 18.7 0.7 1 23 656 678 656 678 0.98 11 13 3.2e-07 1.9e-05 24.5 2.7 3 23 686 706 685 706 0.99 12 13 2.3e-08 1.4e-06 28.1 1.1 1 23 712 734 712 734 0.99 13 13 0.35 22 5.5 3.4 1 19 739 757 739 762 0.89
Sequence Information
- Coding Sequence
- ATGGCCGCCTCCGCGTCCGCCCAACCAGTGCCGGCGGGCGGCAGCTTCGATTTCGATGCTGAGATTGTCTGCCGCATTTGCCTGCGCAGTGTAACGGTGGGCGAAGAGATGCACTTCATCTACGACGAGGCGCCTGTGGAGCAGGGAGCCAATCTCGCCCAGATACTGAACGAGTGCACGCGCTACACCTGCGACCGATTCGACGACAAGATGCCGCTTAAAATGTGCGAGCTGTGCATCAAGGCGGCCCGCCACGCCTTCCGTTTCAAGCGGGATGCGGAAAAGTCCTATTGCTCCCTGATGGCGCTGCTCGGACGCCcgctcaacagcagcagcagcagcgacgtgTGCACCCAAACAGAACAGGTGGCCCTTCTGCCCTGCGAGATGTGCCATGACCAGTTTTTGAACAGCCTGGAGCTGAGACTACATCGGAATAGGGTGCACAAAACCAGGGACAGCGGCActggcaccagcaccagcaataGTGCTGGTGCCAGTGAAGGTGCGGTGGTCCAGCAGCTCAAGTGTAAGTTCTGTCCGCAGCATTTCCCGCATCTGCGCCAGCTTCGCACGCATCTGGCTCGGAGTCATAACCAAACGGAGCGCCTCCAGTGTCCCCACTGCCAGTCAGCCTTCACCCGGCGGGACCATATGCTTCGTCACATACGCAACATACACAAAAAGGAGGCAGACAGCGCCAGGCCGCTGGAGGACGAGGCAACAATGCAGAGCTCTCCCGGGGATGAGCTCGTTTCGGCCGAGGTATTGCTGAACGAGGACGAGAATGACGAGGGCAATGCCTACCAGTGCAATATCAATCCCATATCCagcaacgaggaggaggacgaggtcAATGACGAGGAGGCCAAGAAGGAGCTGTGGCTGCACATCAAACCGGAGCCCTGCCTAGAAGCCGAGGATCTCGATCTGCAGCTCGAGAAGAAGCTGCGCCGGCGGAAAGAGAAGACTGAAACCGAGGAGCGGCAGACCTCCACCGATGCCGCCGCTGTCAAGGATGAGCCTTTGCCCAGCACAgacaccgccgccgccgcccagcCGACGCTGCACATCAAAGAGGAAAGCCAGACGGCAGCTGGCAGCGTGGATGAGGATCAAGGTCGTGATGAAGATGACTTCATAGAAGGTTCCAGCCGGCCTGGCGGGCAGGTGGAGCTGCCCCTCAGTGATGatgcggaggaggaggaggagtacgagtatggggatgaggatgaggatgaggagagCGACTTGGATGACGAGGAgcacgatgatgatgatggagatggagatgcagaGGAGGATGATGCCCCCCCCGGAGACATGGACAAATCCAAATTGGAGATCGTGAGAGATTATCTGAGGAAAAGCAAGCCCCTGAAGCGACGGCGTCGCAACAAACAGAGCGGCGAGGCCAATCCGGAGAATCGCTGCGATGTATGCCAGCGGACATTCTCCCGCCACTGCCACCTGCTGCGGCACAAGCTCTCCCACCTGGAGAAGAAGCCGCACAGCTGCCCGCAGTGCCCCAAGGCATTTGCACGCAGCGACCACCTCAAGGCCCATGTCCAGAGCCTGCACAGCAACAAAGAGCACAAGTGTACGCTGTGCGAGGCCGCCTTTGCCCGTCCCGAGGCCCTCGAGCGGCACAAGGTGAGCAAGCACAACGGTGAGGGCCTGGAGGCGGGCAACGAACTGAAACTCCAGCTGGCGGAGCACACCTGTGAGTACTGTTCGAAGCGTTTCTCCAGCAAAACGTATTTGCGCAAGCACACGCTGCTCCACACCGACTTTCTGTACGCCTGCAAGAGCTGCGAGGAGACCTTCAAGGAGCGCCAGCAGCTGCGCGAGCACGAAAAGAGCCACACCGGGCAGCGCAATTTTCTGTGCTGCATCTGCGGCGACAGCTTTGCCCGCAACGACTATCTGCGTGTGCACATGCGGCGGCATAATGGCGAGAAGCCGTACAAGTGCCGCTACTGTGTGAAGGCCTTTCCCCGGGCCACCGATCTCAAAGTTCACGAGCGGTATCACACGGGCACCAAGCCCAATCTGTGCAACACGTGCGGCAAGAGCTTCCATCGGGCCTACAACCTAACGATCCACATGCGCACCCACACGGGCGAGCGGCCGTACAAGTGCGACCAGTGCCCGAAGAGCTTCACCCAAAGCAACGACCTCAAGGCCCACATCCGGCGGCATACGGGCGAGCGGTACAAGTGTCCGCACTGCGATGCCTACTTTCTGCAGCTGTACAACATGCGCAACCACTGCCTGAGCGCCCACAACAAGCATATTGAGACGAAGACGGGTCGCCTGCAGCGTACAGGCCTCCTCGAGGATGGCACTCAATCCCACCTGACCACTGTCGTGATGCCTCCCGTTCGCTatcagtcgtcgtcgtcggggGGGCCGGATCATCCCAGCCAGATGGAGCAACAAATGGGTGCGCCGGTGGCTGCAATGGGCACGGGGATCGAGAGCTCGTCCGCCAACATCATTCATCATCATTCGCATTCGTCGCCAGAGGCCGCCTCGGCGTACAATGCCTCGCCCGTGACCACAGGGGCTGTgcccacaacaacagcaacgtcGGCGGTGACCACTCTAGATGGTGCCGCCTATGCACCGGCCCCGGCACCGCCAGCACCTGGGAATGCAGCACCCTTTGGGGCCTTCAATTTTCCACCCGTCGTTATGGCGCATCTAATGTACAATCATGCTGGTGGCAGCCAGCACAGTCAGAGCGGCAGTGAGACTGGCAaatag
- Protein Sequence
- MAASASAQPVPAGGSFDFDAEIVCRICLRSVTVGEEMHFIYDEAPVEQGANLAQILNECTRYTCDRFDDKMPLKMCELCIKAARHAFRFKRDAEKSYCSLMALLGRPLNSSSSSDVCTQTEQVALLPCEMCHDQFLNSLELRLHRNRVHKTRDSGTGTSTSNSAGASEGAVVQQLKCKFCPQHFPHLRQLRTHLARSHNQTERLQCPHCQSAFTRRDHMLRHIRNIHKKEADSARPLEDEATMQSSPGDELVSAEVLLNEDENDEGNAYQCNINPISSNEEEDEVNDEEAKKELWLHIKPEPCLEAEDLDLQLEKKLRRRKEKTETEERQTSTDAAAVKDEPLPSTDTAAAAQPTLHIKEESQTAAGSVDEDQGRDEDDFIEGSSRPGGQVELPLSDDAEEEEEYEYGDEDEDEESDLDDEEHDDDDGDGDAEEDDAPPGDMDKSKLEIVRDYLRKSKPLKRRRRNKQSGEANPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHSCPQCPKAFARSDHLKAHVQSLHSNKEHKCTLCEAAFARPEALERHKVSKHNGEGLEAGNELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFKERQQLREHEKSHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLEDGTQSHLTTVVMPPVRYQSSSSGGPDHPSQMEQQMGAPVAAMGTGIESSSANIIHHHSHSSPEAASAYNASPVTTGAVPTTTATSAVTTLDGAAYAPAPAPPAPGNAAPFGAFNFPPVVMAHLMYNHAGGSQHSQSGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00474649;
- 90% Identity
- iTF_00603504;
- 80% Identity
- -