Basic Information

Insect: Drosophila obscura
Gene Symbol: Paris
Assembly: GCA_018151105.1
Location: NW:8355467-8357300[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0012 0.075 13.2 1.6 1 23 116 139 116 139 0.96

2 12 2.6e-08 1.6e-06 28.0 1.3 1 23 144 166 144 166 0.99

3 12 0.0013 0.079 13.2 6.1 1 23 172 196 172 196 0.97

4 12 8.8e-05 0.0054 16.8 5.2 1 21 203 223 203 225 0.95

5 12 1.9e-06 0.00011 22.1 1.2 1 22 229 250 229 250 0.98

6 12 5e-08 3.1e-06 27.0 4.3 1 23 257 279 257 279 0.98

7 12 3.5e-06 0.00022 21.2 1.8 1 23 283 305 283 305 0.99

8 12 8.3e-06 0.00051 20.1 2.8 1 23 311 333 311 333 0.98

9 12 0.058 3.6 7.9 5.1 1 23 339 361 339 361 0.99

10 12 2.4e-05 0.0015 18.6 1.2 1 23 367 389 367 389 0.99

11 12 1.6e-06 9.5e-05 22.3 5.2 1 23 395 417 395 417 0.99

12 12 1.1e-05 0.00069 19.6 6.3 1 23 423 445 423 445 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0012	0.075	13.2	1.6	1	23	116	139	116	139	0.96
2	12	2.6e-08	1.6e-06	28.0	1.3	1	23	144	166	144	166	0.99
3	12	0.0013	0.079	13.2	6.1	1	23	172	196	172	196	0.97
4	12	8.8e-05	0.0054	16.8	5.2	1	21	203	223	203	225	0.95
5	12	1.9e-06	0.00011	22.1	1.2	1	22	229	250	229	250	0.98
6	12	5e-08	3.1e-06	27.0	4.3	1	23	257	279	257	279	0.98
7	12	3.5e-06	0.00022	21.2	1.8	1	23	283	305	283	305	0.99
8	12	8.3e-06	0.00051	20.1	2.8	1	23	311	333	311	333	0.98
9	12	0.058	3.6	7.9	5.1	1	23	339	361	339	361	0.99
10	12	2.4e-05	0.0015	18.6	1.2	1	23	367	389	367	389	0.99
11	12	1.6e-06	9.5e-05	22.3	5.2	1	23	395	417	395	417	0.99
12	12	1.1e-05	0.00069	19.6	6.3	1	23	423	445	423	445	0.98

Sequence Information

Coding Sequence: ATGAATCAAATGTGCAGAGTTTGCATGGCAGTGGCCGGACCATTCACGAACATTTTTGATGAGCCACGAAAAGGGGACACGGACACTCGCATCTCCGAGATGATATCAGAGTGCACAGGATACGTGGTTAGGCGTGGGGATTCGCTGTCTGAAAACATATGTCCGACTTGCCTGGAGGATGCAGTGAGGGCATTCAATCTGAAGAAGACCTGTAAGCAGAGCCATAAACTATTTTTCACACTGATGGAGGAGGATAAAGCAGAGGACAAGGATTCGCCACAGTCGGATAGTCCGAGCCAATTAAAACCCAATGAAGATGCTGGCCATAACATCTCTGAGCATCGCTTCAATTGCTCTTTCTGTACAAACTcatttgcaaaaaaatatcagCTATCTGAACACATCCTCAGTCAGCATGGGGAGCGGCCGTACAAGTGTCCTCAGTGCCCGAAGTCTTTCGCGACATCCAACAGTCTACGGTATCACATGCGTTCCCACGGAGACGACCGACCTTATCAATGCGCTCACCCTCACTGTTCAAAGTCATTTAAACTGAAATTCCAGCTTAATACACACAGCCGTACTCACAGTCCGAAAGAGCGACCGTATCAGTGTTCGGTCTGCTCCAAGTCCTTTAAGAATCTCGATAATtttaccacacacacacgttgcCACACAAAATCCTACAAGTGCACTCAATGCTCCAAAACCTTCTCACAAAAACCTTCTCTCAACGAGCACCTGCGTACGAGCGCTTGCAGGCAATTGCATCAGTGTCCACACTGCCCCAAGTCATATAAGCAACCATATCAACTGACCAAGCACATACGTTCCCACACCAGACCCTACAAGTGCACTCTCTGCCCAAAAGCCTTCTCCATAGAATGCAATCTAAGAGTACACCTGCGAACGCACACGGGGGAACGGCCCTTCCAATGCACCGAATGTACGAAATCGTTTAAACAAAAAGCCCAGCTGCACGGCCACCTCGTTACGCATACTGGTGTGCGACCGTTCAAGTGTACGCAGTGCGAAATGTCTTTTCTGAAAAGATGCAGCCTGCAAGAACATAACCGTACGCACACGGGGGAGCTGCCATATCAATGTTCCCACTGCCCGAGGGCCTTTGAAGTGGAAGAGTATCTGAAGACTCACCTACTTAGGCACAAGGGTAAAGGTCCATACCAATGCCCCGTATGCCCAAAGTCTTTTCCACACAAGTACAAACTACATAAACACAGCCGTACGCACTCAGACGATCGACCCCACCAGTGCCCCCACTGCTTAAAGTTTTTTAAGCGAAAAAACGATCTGAGCAATCACATGCGCTTACACACTGCAGAAGAAAAGACCCAACCTGGGGTGAAAAATAACAAACCAATTGAATCCCGAAAGCGCTTGCAGGCTGTAGAAGAAAAGACCCAACCTGGggtgaaaaataataaaccaaTTGAAGCCCGAAAGCGCTTGCACGCTGCAGAAGAAAAGACCCAACCTGGGGTGAAAAATAACAAACCAATTGAAGCCCGAAAGCGCTTGCAGGCTGCAGAAGAAAAGACCCAACCTGTGGTGAAAAATAACAAACCAATTGAAGCCCGAAAGGAAACGCTCGAATCTGGAGTGCAAACGTTTCAGAATgcttttataaattatttaagatAA
Protein Sequence: MNQMCRVCMAVAGPFTNIFDEPRKGDTDTRISEMISECTGYVVRRGDSLSENICPTCLEDAVRAFNLKKTCKQSHKLFFTLMEEDKAEDKDSPQSDSPSQLKPNEDAGHNISEHRFNCSFCTNSFAKKYQLSEHILSQHGERPYKCPQCPKSFATSNSLRYHMRSHGDDRPYQCAHPHCSKSFKLKFQLNTHSRTHSPKERPYQCSVCSKSFKNLDNFTTHTRCHTKSYKCTQCSKTFSQKPSLNEHLRTSACRQLHQCPHCPKSYKQPYQLTKHIRSHTRPYKCTLCPKAFSIECNLRVHLRTHTGERPFQCTECTKSFKQKAQLHGHLVTHTGVRPFKCTQCEMSFLKRCSLQEHNRTHTGELPYQCSHCPRAFEVEEYLKTHLLRHKGKGPYQCPVCPKSFPHKYKLHKHSRTHSDDRPHQCPHCLKFFKRKNDLSNHMRLHTAEEKTQPGVKNNKPIESRKRLQAVEEKTQPGVKNNKPIEARKRLHAAEEKTQPGVKNNKPIEARKRLQAAEEKTQPVVKNNKPIEARKETLESGVQTFQNAFINYLR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -