Dobs005209.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila obscura
Gene Symbol
Paris
Assembly
GCA_018151105.1
Location
NW:5211006-5213079[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3.1e-08 1.9e-06 27.7 7.1 1 23 143 165 143 165 0.99
2 15 3.5e-06 0.00021 21.2 4.0 1 21 171 191 171 192 0.96
3 15 1.5e-06 9e-05 22.4 2.5 2 23 200 221 199 221 0.98
4 15 0.00021 0.013 15.7 6.9 1 23 227 249 227 249 0.99
5 15 0.0044 0.27 11.5 0.7 1 19 255 273 255 273 0.97
6 15 3.9e-07 2.4e-05 24.2 1.1 1 23 283 305 283 305 0.99
7 15 5.7e-07 3.5e-05 23.7 4.9 1 23 311 333 311 333 0.99
8 15 8.2e-06 0.0005 20.1 2.0 1 23 339 362 339 362 0.98
9 15 4.7e-07 2.9e-05 24.0 6.8 1 23 368 390 368 390 0.99
10 15 6.1e-07 3.7e-05 23.6 2.5 1 23 396 418 396 418 0.99
11 15 1.1e-05 0.00069 19.6 4.1 1 23 424 446 424 446 0.98
12 15 2.2e-05 0.0014 18.7 1.8 1 23 452 474 452 474 0.99
13 15 2.5e-07 1.6e-05 24.8 4.2 1 23 478 500 478 500 0.99
14 15 5.5e-07 3.3e-05 23.8 4.2 1 23 506 528 506 528 0.99
15 15 0.016 0.98 9.7 8.7 1 23 534 557 534 557 0.90

Sequence Information

Coding Sequence
ATGTGCTACATTTCGAGCTTCACAGTTCTATTTTCAACACAAAATAGTCGtgaacaaaaattgtatttgcaaTTCATAAaagtttgGAAAATGGAGGAACTATGCAGAGTTTGCATGGGAACGTCTGAAGCCTTCACAAACATTTTCGATGAGACAGAAAAGTGGGACACTTGCATTGGTGACATGATTGCCCAGTGTACCGGGTACGTGGTTAGGCGAGGTGATTCACTACCAGAAAACATATGTCCGCCTTGCCTTGAGGATGCTGTGAATGCATTCAATCTTATAAAAACCTGTGAGCAGAGCCATCAACTCTATTTCACCCAGATGGAAGAGGATAAGGAAAAAGATCTATGTGATAAACTTGAACAGGAAGATTGGCAAAAgtcaaaaagaggaaaaaatgATAAGGAGTTGGATCTTCTGTTTAAGTGTACTCACTGCTCGAAGTCTttcaaaagaaaatacaatttgcAAAATCACATTCGTACGCACACCGGTGAAAAACTTCACCAATGCTCTCACTGTTCCAAAACCTTTGATCGAAAATCAAGTCTTCAAAGTCACATACGTTATATCACTGGGGAGCGACCCAACAAATGTTCCCACTGCTCAAAATCATTCGTAAGCATGAGCGCACTGAAGGTACACATCCGTACACATACCGGGGAACGACCCTATAAGTGCTCCTACTGCTCAGACTGCTTTAAAAGTAAAAGCGAACTTACAGTGCACATCTGTAAGCACACGGATGAACTACCCTACCAATGCCCACAATGCCTAAAGTCATTTAAGCTAAAATCGATTCTCCGAAGACACTGTCCTGCCCACACGGCGGAGAGACTTTACAAGTGTTCTGACTGCTCAATGTCCTTTATTAGTCAAAGCAAGCTCAAAATGCACATCCGTGTTCACACAGGGGAAGAGCCTTACCAATGCACCCACTGCCTCAAGTCATTTAAGCGACAGGCTAATCTCAAGAGACACAGTCGTATCCACACGGGAGAGAAACCTTATAAGTGTTCTAAATGCTCAAAGTGTTTTGCCATTGGCTCCAATCTCCAGGTTCATATCCGTCGATGGCACTCAGATGTACGACCCTACCAGTGCTCTCACTGCTCGAAGTCGTTTACAGAAAAATCTCATCTCAAGATACACATCCGTAAACACACTGGGGAGCGACCGTACAAGTGTTCACACTGCTCCAAGTCCTTTACTCGAAACGGACCTCTCAAGATTCACATCCTTACGCACACGGAAGGATTGCCCTACAAATGCACCGACTGCTCGAAGTCATTTCAACTAAAATCCCAACTCCAAAAACACACCTTTACGCACACAGGTGAACGACCGTTCAAATGCTCCGACTGCTCAAAGTCATTTCTACAAAAATTCAAACTTATTGCACACATCCGCTCTCACACACGACCTTACAAATGCTCCCACTGCTCGAAAGGCTTTATAGACAAATCCAATCTTAAAAGACATACCCTTACGCACACGGATGAAAGACCCTACAAGTGCTCCCACTGCTCGAAATCATTTCAAGAAAAATCGAATCTCAGGGTACACATCCGTTCTCACACAGGGGAGCGTCCTTTCAAGTGTGCCCACTGCTCAAAGACATTTCGATACAAAAACAATAGCTACAAAAGACACATGCGCACTCACAAAAACACTAAAAAGAGTGCCACTCCGGCAGTCTTTGAGATCACATCCGCAAGATCGCTGAGAAAGGATGATTCGATTGCGCTAACTGCAGAACGCGATTTTTAA
Protein Sequence
MCYISSFTVLFSTQNSREQKLYLQFIKVWKMEELCRVCMGTSEAFTNIFDETEKWDTCIGDMIAQCTGYVVRRGDSLPENICPPCLEDAVNAFNLIKTCEQSHQLYFTQMEEDKEKDLCDKLEQEDWQKSKRGKNDKELDLLFKCTHCSKSFKRKYNLQNHIRTHTGEKLHQCSHCSKTFDRKSSLQSHIRYITGERPNKCSHCSKSFVSMSALKVHIRTHTGERPYKCSYCSDCFKSKSELTVHICKHTDELPYQCPQCLKSFKLKSILRRHCPAHTAERLYKCSDCSMSFISQSKLKMHIRVHTGEEPYQCTHCLKSFKRQANLKRHSRIHTGEKPYKCSKCSKCFAIGSNLQVHIRRWHSDVRPYQCSHCSKSFTEKSHLKIHIRKHTGERPYKCSHCSKSFTRNGPLKIHILTHTEGLPYKCTDCSKSFQLKSQLQKHTFTHTGERPFKCSDCSKSFLQKFKLIAHIRSHTRPYKCSHCSKGFIDKSNLKRHTLTHTDERPYKCSHCSKSFQEKSNLRVHIRSHTGERPFKCAHCSKTFRYKNNSYKRHMRTHKNTKKSATPAVFEITSARSLRKDDSIALTAERDF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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