Basic Information

Insect: Drosophila novamexicana
Gene Symbol: -
Assembly: GCA_003285875.3
Location: NW:10310580-10314838[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.13 7 6.9 2.3 1 23 57 79 57 79 0.96

2 8 0.0019 0.1 12.6 0.7 2 23 116 137 115 137 0.96

3 8 0.021 1.1 9.4 1.4 1 21 143 163 143 164 0.94

4 8 0.75 40 4.5 2.5 2 23 516 538 515 538 0.93

5 8 6.5e-06 0.00034 20.4 1.2 1 23 666 688 666 688 0.98

6 8 1e-06 5.3e-05 23.0 3.6 1 23 694 716 694 716 0.98

7 8 0.00035 0.019 15.0 2.9 1 23 722 744 722 744 0.98

8 8 0.00028 0.015 15.3 0.1 1 21 750 770 750 771 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.13	7	6.9	2.3	1	23	57	79	57	79	0.96
2	8	0.0019	0.1	12.6	0.7	2	23	116	137	115	137	0.96
3	8	0.021	1.1	9.4	1.4	1	21	143	163	143	164	0.94
4	8	0.75	40	4.5	2.5	2	23	516	538	515	538	0.93
5	8	6.5e-06	0.00034	20.4	1.2	1	23	666	688	666	688	0.98
6	8	1e-06	5.3e-05	23.0	3.6	1	23	694	716	694	716	0.98
7	8	0.00035	0.019	15.0	2.9	1	23	722	744	722	744	0.98
8	8	0.00028	0.015	15.3	0.1	1	21	750	770	750	771	0.96

Sequence Information

Coding Sequence: ATGAAAATCATCGAAGAGCGGCCAAATATGATAACGGTGCCGGTGCATGACTGCAAATCCGAGGATGAGCTTAAATTCATAGCGAGCCTCGGCACGTTCGATCAACAGCAAAAGTTATTTGTGACGTCACCTTGTGAAAATATTGCCCCGGCCGACACTTTCGgtgcatttgcatgcaaaatttGCAGCTTTACGTGTGAAAATCATCTGGCGCTGGCCTCGCACCAGATTAACCACCAACTAAATCGACATTTCTGTTGCTATGGATGCGGCGTCTGGTGCAACACACTTGAGGAGATTCTGGAGCACGAATTTCGCAAGCATGCGGGCGGTTTAAATGGATCAAGCTGTAGGATTTGTGAGTTGAATTGTAGCGATGCCGCAAGTCTGGCCAAGCACATGAGCAGCCACTTTTATGTACGCCGTTTTGTCTGCGCGGTATGTCGCCGGCATTTTGAGACGCGCCAGGGATTGCAGCTGCATCGGCAGCACAGCAAGGAGGTGTGCGGTCAGGTCGAATATGCTGATATACATGGCAATGTTGGCCAATTGGTGGCGGTCAGCAAGCTCGACGCCAAATTGCCTGAGGAACTGGCATGTGATGTTGAAATTAAAACGGAGCCGCTGGAAGCCGAAGAGCAACAGCCGGAAACAGAGCATGAGCAGGAAATGGCGGATATTGTTATCAAAACAGAGCCGGAGTTCGAAGCAGATGAGTTGAGCTTTGGCCAGGATGCCAACTGGATGAACAACAGCCTTGCAGGACAACTGCGCGGCAAATTGCGTTTGCCTGCAATACAGAAACCAATAAAAGTTGAAACTGTAACGAGCGCTGAAACACCAACGGCTGCACCCCCAACCATACAGTttgtGCCCGCAGGCAAATGGAAGCCTATACCAATACCTAACACGAATGCATCGGTAAAGCtgccaaacattttaaagCCCAAAAAAGGCAATAATCagcagaaaaatattttgaaaaagaaCGTCTTGCAATCGTTGAAAAACAAGCCAAATATTGCAGCCAACATCTTAAAGGTATTGCCCAGCAATTGCATGCTTATCAAATTGCCGCCAAACACCAAGATAGTTAAAATAGCGCCAAGCCCGACGAGCGTCAATACGAATAGCTGCACCATTGGCAGCAAGATTATTACACTGCCAAGTGCCATGTCCATAAGCTCAGTTTCCGTTGGTTCCAAGAACCACTCGGTCGCCACAGTTCCAAGCCCAACTGCACCCAGTACGCCACAAGCAGAAGGCACACAAAAGGCGGCCATAAATCGCAACGCTTACTTTAATGCCTTAAGCTTATTCGAGAGCTTGCCCGAATCTCGCAAGATCATCACAGAATTCCAAAATCAAATACGCAGCATAGAGCAGACATTGCCACTGCCCGGCAGCGTATTGCAAACGCCCAAGAGAAACAACAATCTAGTGTTGCCATCGCAGCTGGAGGTGCTTCGGCTGGCTCCCACCAAATCGAGCAATGTGAAAGTGCGTCAATTGCGCTATACGTATCCCAATCATCGTTTTCACTGGGAGTGTCCCAAATGTGCGCGCTGCTACGAACAGTATTTACCATTCTGTAACCACATGACCCAAGTGCACGGCATAGCGGAAGCAGAGTTCGAGCATATAAAAGTGGAGGTCAAGACTTACAAGAaATTGAATTTATCCAAAATGTCTCCAGCCACAAGTCCAATAGAGATGACCCCAGCTGCGCCTACTACAGCTGCGGAAGCTCCTGTGATTCCAGGTGCTGCAGAACCAACTGCAGCTTCTACTGAGCGAGCTCCAGAAGCGTCTACAGTAACAGGACCAGATTCTGTAGTTGAATCAGCAGAAGTAGCTCCTGTAGAAGCCGTTTCTCTCTCTTCTGCAAAGCCAACTCCTGTAGCACCTGTGGCGCCTGCAGCTCTTGCGTCAACGCCACCCGCCTCAGCTCCTGCTAAGTCAACACGACCAGCTCCAATTGTTCGTCCTGCTCAGTATCAGTGCGAGGATTGTTCCAAGTGCTTTACCACTGTGGGTGCCCTGCGTATCCACAAAATGATCCACACTGGGGAGCTGCCGCATAAATGCAACTACTGTGACAAACGCTTTCGTACACCCGGCCAGGTGCGCGTCCATCAGCGCCGGCACACAGGTGAAAAACCATTCAAATGCAAGGTTTGCTCGCTGGATTTCACACATCGCGAGACTCTCATCTCCCATCTGTCGCGTCACATTGGCATGAAACGTTACAAGTGCTATGGTTGTGACAAGAACTTCGTGGTGGTCAGTGGATTGCGCGCACATCGCCGTCTACGACCAGATACGTGCGGCAAGGTCAAGTTTACGGCACGTGCACACGGTCCCCGAGTTCGTGTTATACGAGGCGAGGTCGTTTTCGAATCGCATCCCGAGCATAATGGTTACTTACGCAGTGAGGATCCTTTGAACATTATGTCTGAGATTAATCAGGCCTCCAAAGAATCATCTGTTGCTTCCGAGTCTAGCTAA
Protein Sequence: MKIIEERPNMITVPVHDCKSEDELKFIASLGTFDQQQKLFVTSPCENIAPADTFGAFACKICSFTCENHLALASHQINHQLNRHFCCYGCGVWCNTLEEILEHEFRKHAGGLNGSSCRICELNCSDAASLAKHMSSHFYVRRFVCAVCRRHFETRQGLQLHRQHSKEVCGQVEYADIHGNVGQLVAVSKLDAKLPEELACDVEIKTEPLEAEEQQPETEHEQEMADIVIKTEPEFEADELSFGQDANWMNNSLAGQLRGKLRLPAIQKPIKVETVTSAETPTAAPPTIQFVPAGKWKPIPIPNTNASVKLPNILKPKKGNNQQKNILKKNVLQSLKNKPNIAANILKVLPSNCMLIKLPPNTKIVKIAPSPTSVNTNSCTIGSKIITLPSAMSISSVSVGSKNHSVATVPSPTAPSTPQAEGTQKAAINRNAYFNALSLFESLPESRKIITEFQNQIRSIEQTLPLPGSVLQTPKRNNNLVLPSQLEVLRLAPTKSSNVKVRQLRYTYPNHRFHWECPKCARCYEQYLPFCNHMTQVHGIAEAEFEHIKVEVKTYKKLNLSKMSPATSPIEMTPAAPTTAAEAPVIPGAAEPTAASTERAPEASTVTGPDSVVESAEVAPVEAVSLSSAKPTPVAPVAPAALASTPPASAPAKSTRPAPIVRPAQYQCEDCSKCFTTVGALRIHKMIHTGELPHKCNYCDKRFRTPGQVRVHQRRHTGEKPFKCKVCSLDFTHRETLISHLSRHIGMKRYKCYGCDKNFVVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIRGEVVFESHPEHNGYLRSEDPLNIMSEINQASKESSVASESS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00475497;
90% Identity: iTF_00506403;
80% Identity: -