Dnov003737.1
Basic Information
- Insect
- Drosophila novamexicana
- Gene Symbol
- -
- Assembly
- GCA_003285875.3
- Location
- NW:3479855-3482794[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 6 4.4e-06 0.00023 21.0 0.8 1 23 245 267 245 267 0.99 2 6 1.6e-05 0.00085 19.2 2.3 1 23 273 295 273 295 0.98 3 6 2e-06 0.00011 22.0 1.3 1 23 454 476 454 476 0.98 4 6 5.3e-05 0.0028 17.5 4.9 1 23 482 504 482 504 0.98 5 6 0.8 42 4.4 2.5 1 23 510 532 510 532 0.98 6 6 0.0014 0.073 13.1 2.0 2 23 569 590 568 590 0.97
Sequence Information
- Coding Sequence
- ATGTATTGCGGCAAGGGCATGGAGCTTGCGTCCGCTGGCTGCGCTGACTGCTGCAGCGACTGCGCCAGCGCGGCGCCCACTTGCTGCACTGCTTCGGGCTGCTGCGATGCTGCCTGCTGCGACGTCAATtgtcagctgctgccgccagaTGCCAATAATTATGAATACCACGAGCCGGAAGAGAACTTTGTGTCCATTGACGATGCCAAGATAAAGAGCCTGCTGCTCCAGATcggaaagcagcagcagcagcagcaggagctgcgacgccagcagcagcagctgcgacgccagcagcagcagcagcagctgcgacgccagcagcagcagcaacaacagattATCGAACTTTTGGACGATGATGAGACTAGCGTGGAGCAGCCGCCGCCAATGTTAATTAGCGCAGCGCACAGCTTAAATCCACGGAAACGCCTTTTGaccgaaaaacaacaaatagccAAGAAACTGAAGCAGCGACAACATCGAATTGTGGCCCGGATTGAGCTAAGCGACAGCGAATCCGAGACGGAAATGCCGGAGCCAGCACCGAACAGAGATAGCGAAGAGAATTTGCCTTTGGCTACTGTCAGCTGCGAGCTAGTGGAACCAACGCAGATCATTGAGCTGCCGTCGGACGAGGAGGAGCAGTTCCAGCAGCGGAAACCGCCAGCTAAGGCAGCGCCCCGCAAGCGGCCACCGAGACCCTATATAAAGCGACGCGGCCGGCACTTCTATCAGTGCCAGGCATGCGGCAAGAAGGTGCAGTCCAATTACAATCTGCGTCGCCACATGATGATCCACACAGGTGAGCGACCCTTTCCCTGTGATTTGTGCGAACGACGCTTTCGCGAGTTCAGCGACCTCAAGAAGCATCGCCGACGACACATGAACGATCCGCGCTATATATGCATGATCTGTCGCTTGCATCCGCCCATGGAGCAGGACTCAACGCGCTGTGCGGAATGCGAGGGCAAGAATCTGCTACTAGGACCGCAGGACTGTGATGATGTGGAGACTGAAAAGGTGGCGGACGAAGAGGCGGAACAAGAGCTGGATCAGGAATCggaccaggaccaggaccaggAATTTGTCGTGGAGGAGCATAACGTAAATAAATTTACGTCTTTACCCGTGGCAACCGTATTGGCTTCACGGCCGCCCACGCTGCTGGTTACGCTGgtgcccacgcccacgccagCCCCAGCCCTACCAGTTAGTGCACCTAtagccacacccacacccgTCCCGCCGTCACGTCCACCATTGccgcgcagctgcagcagcgccaactCCTCCTCCTCGCTTAGCAACGATGTGGCGCCAAGGAGGCTGGCCAGAAATTCGCGCAATCGGCGCTCCTATCCGTGCCCGTTGTGCCAACGTCCGTTCGGCACGCGCCACAATCTCAAGCGGCACTACATGATCCACACCGGCGAGAAGccattcagctgcagcaagtGCCGCAAGCCGTTCCGCGAGTGCTCTACCCTCAAGAAGCATATGGTGACCCATGTGCGCGAACGCTGGTACAAGTGCCTCAGGTGTCCCGCCAAGTATCAGGATTATTTGCACTACACGGAACACAAGGCGACCCATGGCCAGAACACGCAGCTGGAGACGGACACAAATGGTCGCCGCAGACAACGTTCATCTGAGAGCGaggatggcgatggcgatggcgatagCTCTGTGGATGATTGGCTGGAGTGCTGCGAGTGCCAGCTACGTTTCACCCAACTGGATGCCTACACGGAGCATCTGAAGAAGCACGACCTGGAGCTGTATGGCCTGAGTGTCGACGATCTGGACGATGAGGATCAGGATGTAGATGTGGCCTAA
- Protein Sequence
- MYCGKGMELASAGCADCCSDCASAAPTCCTASGCCDAACCDVNCQLLPPDANNYEYHEPEENFVSIDDAKIKSLLLQIGKQQQQQQELRRQQQQLRRQQQQQQLRRQQQQQQQIIELLDDDETSVEQPPPMLISAAHSLNPRKRLLTEKQQIAKKLKQRQHRIVARIELSDSESETEMPEPAPNRDSEENLPLATVSCELVEPTQIIELPSDEEEQFQQRKPPAKAAPRKRPPRPYIKRRGRHFYQCQACGKKVQSNYNLRRHMMIHTGERPFPCDLCERRFREFSDLKKHRRRHMNDPRYICMICRLHPPMEQDSTRCAECEGKNLLLGPQDCDDVETEKVADEEAEQELDQESDQDQDQEFVVEEHNVNKFTSLPVATVLASRPPTLLVTLVPTPTPAPALPVSAPIATPTPVPPSRPPLPRSCSSANSSSSLSNDVAPRRLARNSRNRRSYPCPLCQRPFGTRHNLKRHYMIHTGEKPFSCSKCRKPFRECSTLKKHMVTHVRERWYKCLRCPAKYQDYLHYTEHKATHGQNTQLETDTNGRRRQRSSESEDGDGDGDSSVDDWLECCECQLRFTQLDAYTEHLKKHDLELYGLSVDDLDDEDQDVDVA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00475484;
- 90% Identity
- iTF_00551122;
- 80% Identity
- -