Basic Information

Insect: Drosophila novamexicana
Gene Symbol: Kr-h1_1
Assembly: GCA_003285875.3
Location: NW:7612430-7631030[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0037 0.19 11.8 3.0 1 23 148 170 148 170 0.98

2 8 1.6e-06 8.3e-05 22.4 0.5 1 23 229 251 229 251 0.99

3 8 1.9e-05 0.001 19.0 2.3 1 23 257 279 257 279 0.98

4 8 3.6e-06 0.00019 21.2 3.1 1 23 285 307 285 307 0.99

5 8 3e-07 1.6e-05 24.6 1.3 1 23 313 335 313 335 0.98

6 8 0.0001 0.0055 16.6 1.4 1 23 341 365 341 365 0.99

7 8 0.53 28 5.0 3.7 1 23 371 393 371 393 0.94

8 8 8.2e-07 4.4e-05 23.2 0.6 1 23 399 421 399 421 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0037	0.19	11.8	3.0	1	23	148	170	148	170	0.98
2	8	1.6e-06	8.3e-05	22.4	0.5	1	23	229	251	229	251	0.99
3	8	1.9e-05	0.001	19.0	2.3	1	23	257	279	257	279	0.98
4	8	3.6e-06	0.00019	21.2	3.1	1	23	285	307	285	307	0.99
5	8	3e-07	1.6e-05	24.6	1.3	1	23	313	335	313	335	0.98
6	8	0.0001	0.0055	16.6	1.4	1	23	341	365	341	365	0.99
7	8	0.53	28	5.0	3.7	1	23	371	393	371	393	0.94
8	8	8.2e-07	4.4e-05	23.2	0.6	1	23	399	421	399	421	0.98

Sequence Information

Coding Sequence: ATGGTCTACTATCCCGCTAATCAGCTGCTTATAAAGACGGAGCAGCCCAGTCAGACGCAATTCTGCCTGCAGACGCCACTCACCGCAACGAGCGGTGGCGGCATTGGTGTTGCGCCACCTGGCGGTCAGCATGAGCACTACGAGCTATTGCAGACGCCGCAGCAGCGacaattgcagcagctgcaacagcagcagcagcagcaacagcaacaacagcaacagcaacagcaacttgcCAGCTATCAATTGGtcctgcaacaacaacaacaacaacaacataaaagtattacaacaacaacagcaacaactacagcagcagcagcaacaacaacaactgccacaCAGCAGCGCATCAAAACAGAGCTGCCCTTGGCGTATGGCTCAGCGGCGACAACTAAAACGCTTGCCACGCCCCGCAAGCCCAACATCAACAAGCCGCAGTTCAAGTGCGAGCAGTGCGGCATGACCTTTGGCAGCAAATCGGCGCACACCTCGCACACGAAATCGCACGCCAAGAATGCGGATCTCGCACTGGGCCTTAAGGGTGCCACAATgggcgccagcagcagctcgagcaGCTCCGGCATGCCGCCGATCGAGCTGAACGAGTCGGGCCTGCCGCTGGGCATACCCAAAAGTCCGACCATCAAGCCGCTGGCCAATGTGGCCGCCGGCGCCGATCCCTATCAGTGCAATGTGTGCCAGAAGACATTTGCGGTGCCCGCGCGTTTGATCCGGCATTACAGGACGCACACGGGCGAGCGTCCATTTGAGTGCGAGTTCTGTCACAAGCTGTTTAGCGTTAAGGAGAATCTGCAGGTGCATCGGCGCATCCATACCAAGGAGCGACCGTACAAGTGCGATGTGTGCGAGCGTGCCTTTGAGCATTCCGGAAAACTGCATCGTCACATGCGCATCCATACGGGCGAACGGCCGCATAAGTGCTCCGTCTGCGAGAAGACATTCAtacagtccggccagctggtTATCCATATGCGCACGCATACCGGCGAGAAGCCATACAAATGCCCGGAGCCCGGCTGCGGCAAGGGCTTCACCTGCTCCAAACAGCTGAAGGTGCACTCGCGCACCCACACCGGCGAGAAGCCCTACCATTGCGACATCTGCTTCCGTGACTTTGGCTACAATCATGTGCTCAAGCTGCATCGTGTCCAGCATTACGGCGCCAAGTGCTACAAGTGCACCATATGCGATGAGACCTTCAAGAACAAGAAGGAGATGGAGGCGCACATTAAGGGCCATGCCAATGAGCTGCCCGAGGATGAGGTGGAGgccgctgcagccgctgcagcagtcgcagttgccTCATCCATAGCCAGCAACTCggagagcagcaacaattcgCCGCCCAGCTCGCCGCCGGCTGTCAAAAAGCCGCGTCAGCCGCGCAGCATTaaggcagccgcagcagccgctgctgccgctgtggcagctgccagcGCAGCGCCGCTTTCGCCCGGCTCCATCTCATCCATATACTCGCCGGCCAGCAGTCAGGCCTCGACGCCGCCGCAATATCTGGCCACAACGGCGCCCAACGAGCCGGATGCGCTGAGTCGCGATAGCGGCGTCGCCAGCGCCCCTCAGCTGCTGTCCAGCTATGCGGACGAGGAGCTGCCCACGGACTTgagcatgcagcagcagcagccggcgccTCAAATGATCTACTATCAGCCACAGACGCCCAGTCTAGTGGAGCTGCAGCCCAGCACGCCCGCACCTGCGCCCTCCGGCCTGTCGGCGCTGCTGCAGGCGGCGAGCATGGCGCGAGACGAACACGCCGATGACAATGACAACGATGAGGATGTGCAGGTGGCTGCCTTGCAAATGATGCAGCTGCGACGCGGACATGCCGCCACGCCACAGTCCCAgccacaggcacaggcacagccccaatcccaatcccaatcccagcCCACGTTGCATGTCAGCGATCTGGCGGCCAACTATGATGACACGCACGAGGCGAATGTGCTCATCGAGCACTTCAAGCGCGGCGACTTGGCGCGTCATGGACTGCACAAGGGCTATGTGCCGGTGCCCATGTATGAATCTGCCCTGCCCAATGCGGACATAGTGCGTCGCGTTGAGGCGGCCATTGGACTGCGCTCCAGCACCGAATCGCCAGAGCGCAGCTCCTCGCCCGAAAGCGATTCCCTGATGATGGCCGATCGCAATGTGTTGACCCTGCCGCTGCGCAAGCGCAAGCACTACATGAACGAGGGCGAGGCCAGCAGCGTTGTTGgtggcggcgtcggcggcggcagcagcagcggcgccaaTAATAGTGCAGCGGGCGGCGTCAACGAGACGGTGGCAACAATAGCCACTGCACCAAATGCCACAACAGATGTTGCCGCCAATGCTGCCGGCGCCAAGGTGATGCGCATGAGCTCCGTCATCCAGTTTGCCAAGGCCACGTAG
Protein Sequence: MVYYPANQLLIKTEQPSQTQFCLQTPLTATSGGGIGVAPPGGQHEHYELLQTPQQRQLQQLQQQQQQQQQQQQQQQQLASYQLVLQQQQQQQHKSITTTTATTTAAAATTTTATQQRIKTELPLAYGSAATTKTLATPRKPNINKPQFKCEQCGMTFGSKSAHTSHTKSHAKNADLALGLKGATMGASSSSSSSGMPPIELNESGLPLGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCERAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGAKCYKCTICDETFKNKKEMEAHIKGHANELPEDEVEAAAAAAAVAVASSIASNSESSNNSPPSSPPAVKKPRQPRSIKAAAAAAAAAVAAASAAPLSPGSISSIYSPASSQASTPPQYLATTAPNEPDALSRDSGVASAPQLLSSYADEELPTDLSMQQQQPAPQMIYYQPQTPSLVELQPSTPAPAPSGLSALLQAASMARDEHADDNDNDEDVQVAALQMMQLRRGHAATPQSQPQAQAQPQSQSQSQPTLHVSDLAANYDDTHEANVLIEHFKRGDLARHGLHKGYVPVPMYESALPNADIVRRVEAAIGLRSSTESPERSSSPESDSLMMADRNVLTLPLRKRKHYMNEGEASSVVGGGVGGGSSSGANNSAAGGVNETVATIATAPNATTDVAANAAGAKVMRMSSVIQFAKAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508507;
90% Identity: iTF_00617072;
80% Identity: -