Basic Information

Insect: Drosophila novamexicana
Gene Symbol: salm
Assembly: GCA_003285875.3
Location: NW:9662949-9671009[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.1e-06 0.00011 22.0 1.7 1 23 341 363 341 363 0.98

2 8 3e-05 0.0016 18.3 3.5 1 23 369 391 369 391 0.98

3 8 2 1.1e+02 3.1 2.5 5 23 633 651 630 651 0.84

4 8 3.1e-08 1.6e-06 27.7 0.2 1 23 657 679 657 679 0.98

5 8 0.00093 0.049 13.6 0.9 1 23 689 711 689 711 0.98

6 8 0.019 0.99 9.5 0.1 2 23 916 938 916 938 0.95

7 8 1e-05 0.00053 19.8 5.0 1 23 1069 1091 1069 1091 0.96

8 8 8e-08 4.3e-06 26.4 0.7 1 23 1097 1119 1097 1119 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.1e-06	0.00011	22.0	1.7	1	23	341	363	341	363	0.98
2	8	3e-05	0.0016	18.3	3.5	1	23	369	391	369	391	0.98
3	8	2	1.1e+02	3.1	2.5	5	23	633	651	630	651	0.84
4	8	3.1e-08	1.6e-06	27.7	0.2	1	23	657	679	657	679	0.98
5	8	0.00093	0.049	13.6	0.9	1	23	689	711	689	711	0.98
6	8	0.019	0.99	9.5	0.1	2	23	916	938	916	938	0.95
7	8	1e-05	0.00053	19.8	5.0	1	23	1069	1091	1069	1091	0.96
8	8	8e-08	4.3e-06	26.4	0.7	1	23	1097	1119	1097	1119	0.98

Sequence Information

Coding Sequence: ATGTGTTCAATATTTCGCAACCGCATCAATTACCGAAGCACAGGTACGCGCAGTGGCTCCTCTAATGGTGGCAGCTCGGTAGGTGCAGACACTACAGGCGACAGCAGTCTGCTAGCCAAGGAGCTGAATGCGGACAGCAATAACAACGGCAGCGCAGCTGACGAAATGCCGGAGCCGGAGGCGGCGTTACAGCTAGAATCGGAGACATCGTTGCCCTGCGCTGACCAGCCGGAGAACAGTAATGAGGCGCTGGATTTATCGGTTATCTCCGGCAGCCGGTTGCCTACAAGCGGGCACGTGGCACTTGAAGCTTTACAACATACCAAAGTGGCGGTGGCACAGTTTGCAGCCACTGCGCTGGCGGGAACGACTGATCCAAATGATCTGGCTATGGTGCAATCGACGATCTTCAATGTACAGCGGCAGCATctgatgcagctgcagctcatccAGCACCTACAGAGTCAATTGAAGCGGGCGGGTGGCGTGGTAGCTGCGCTGAGTAGGCCGGGTCAAAGTTATGCTGAGCCTGAAGACGAAGAAGACGAGGAGGACGAGGaggagccgccgccgccgccgctaaATCCTTCCAAAGAGCAGCCGAAACTAAATGGCGAGGAAGCAGAGATTGATCATGAAAGGCTGGAGGAGAGTTCAAAGACTGATGAACAGGAAATGTCAATGGAAATAGAGGCAATATCCAATGAGTGCAATAGGGAACGAGAGGTGCTCCTCACCAAAATAGAACGCGAGCGTGAAATTGAGGTTGAGGCCGAACGCGAGCTGGAGAGTGAATATAAACCGATAATGTGCGACATCAGCTCTAGTCTGGCATCCAGTATCATCACCAATCACGACCCACCGCCGGCGCCCAATGAGCCCAACTGCCTGGAGATGCTGCAACGCCGTACAGAGGAGGTGCTGGACTCGGCGTCGCAGAGCTTGCACGCCGCCCAAATGCAGGAGGAATATTCGGAATATGCCTCCAAGGAAGCACAGAGTCGTGGTGAGATCTTCAAGCATCGTTGCAAGTATTGTGGCAAGATCTTCGGCAGCTACTCGGCCCTGCAAATACACCTGCGATCCCACACCGGAGAGAGACCCTTCCATTGCAACGTATGTGGCAGCAAGTTTACCACCAAGGGAAATTTAAAGGTGCACTATCAACGCCACACGCAAATCTTTCCTCcaatgctgctgccgcctgtGGTCAACGGGGGGCCACCGCCGGCAACGCCCGAGCAGTTTGCCGCTCTGCCACCTATTCGTTTACCCTTTGTGACGCCAGCGCCCCTGGCACCGCCTCCGCCGCCTACCGTAGGTCAACCCAGCGGGGATCACACACcattggagcagcagcagcaggagccaCAGTCGCTGGCAATGTCGGGACATCTACAGCAGGCCGAGGATCTAAGCAAGCCGGCCAGAGAGATGTCGCACTCTCCCATGCAACCCGCGCAGACATCCAAGTCCCTGCCCGAACGGAGCAGAAATCAAAGTGCAACGGAATCTGTCCAGCCGCCGGTAGTTTTCACCGAGAAACAGGAAAAGGATAAAACGAAGGACAGTCCAAAGCCAACAACGCCGCCGACGACGGCGAATCGCCGAAACGGCAGCGTACGTAAACGTCAGACGAGCAATGCGGGTAGTCCGCCCGGAGATGATCGCGAACATCCCGAGCATCTACAGATGGCCAAGCTGGTGCGACGCTCTTCGGCCAGTCGCGATGGGACTGTGGCACTGCCAGGCGAGTACTCGTTGGCTCAGATGGAGCGCATCATTGACAAGTCGTGGGAAGATCTCATTGAGATAGATAAAACATCGGAGACGTCAAAGCTTCAGCAGCTGGTTGACAACATCGAGAACAAGCTGACCGATCCGAATCAGTGCATTTTCTGCCAGAAGGTAATGTCCTGCCGCAGCTCACTGCAGATGCATATACGCACTCACACTGGCGAGCGACCTTTTCGCTGTAAGATCTGCGGACGCGCATTCGCCACTAAGGGCAACCTGAAGGCGCACATGAGCATACACAAGATAAAGCCACCCATGCGCAGTCAGTTCAAGTGCCCAGTATGCCACCAAAAGTTCTCCAACGGCATCATCCTGCAGCAGCACATTCGCATCCACACCATGGACGACGGCAGCGGCAATCAAGGCCAtggtcagagtcagagtcagagcaTTGGGCTTGGTGATGCTGAGCGCTTGGGTATTGAGGATCAGAATTCAAACAAGTCGCTAGGCACCTCAGACACTTTGGACTTCTCAACCACTATTTCAGACCACTCTGGCCAGCGCTCGGAGTCTTCGCAAGGAGGCGATTTCGACGAGTTCATGACCATGGACAGCACTGACGATTCGCGTGACAATTCAAGTGCAGCCACGGCCACGCTTCTTGACAGAGATAGAAGGACTGGCCACGATGACGACCGCTCCAGATCGGATTTAGAAGGTGGTGGTCGTGAAAGCACCAGCGGCGAGATGCCTGCAATGGACCTTTCATCGCCATCTTCGTCGTCGGCGGCAACAGCGGCTGCGGCGAGGCTCTTTGGCGTCGGTAACAGTACAACAGCTGTTGGTACTGGAGCCCTACCGATGCTTGGCATGCCGATGCCTCCGAATCTGTTGCTGATGGCGGCGGCGCGCGATGAGATGCACGCGCTAGGGCAAACGCATGCCAAGTTTCCGCTGCTGCCCTTCGGACCGCTCGGATTAATGGGTCTGCAGCCGCCCCCAAATGTGTGCAATTTGTGCTTCAAGATGCTGCCCAGCCAGGCTGCCCTGGAAACTCATCTACAGAACGAACATGCCAAAGAAATGACGGTTCCTTCCGCCCGAGCCCACTCCAACGAAACTATATCACCGTATGGGGCAAAGctCACTCTCAATCCAAATCTGTTTGCAAAGAAGCCGAAGCAATCGCAGGAGATGGCGCCAGCGGAGCCAGTCACGCCATCGGCGGCACCTATTAAAGAGGAGCCTGAGTCCGATCGGCTGCTAGTCGACGAGGGTGGCGATAACGCTTCAAATACGGCCGCTACCAACTATCAGCACGAGACAGCCGCCGATGCGGAGCAGTCTCTGATGAAGATGCAGTTGCATGCTCATCGCTTTCCAGCTAGTCCGCTGGACTTTCAGCAAGCACTTATGTCGGCAGGCCCGCCTAGCTCTAGCCTCGATCCGCCGGTTAACAACAAGCACTTCTGCCACGTCTGCCGACGCAATTTCAGTTCTAGCTCAGCGCTGCAGATTCACATGCGCACTCATACCGGGGATAAGCCCTTTCAGTGCAATGTCTGTCAGAAGGCCTTTACCACTAAGGGTAACCTTAAGGTTCATATGGGCACGCATATGTGGACAAATCCTACATCGCGTCGGGGCCGCCGTATGTCCCTAGAGTTACCGATGCGCCCTGGACCTGCACCGGGCGCTGCACATGGAGCGCCTTCTGCTGAACAGGAGTTCATGCAGCGCCGACCGGAACTCTTTTTTCCCTATCTGCCACCTTTCTTCAACGGAATTCCACCCAAGCCCGGTGAATTAAGCCCTGGCGCGTTTACCAACATACCTCCACCGCACTTTGCAAATGGAGCCAAGTATCCATATCCGCCAGGTCTGCTGAGTTTTCCAAACTTCTTAGGTGGCGCTGGTCTTCATCACCAGTATGCCCATGGAGTGGAGCGAAGTAACAGCAAGTCACCAACGTCGGAGCCGGCGCAGAGCCCTGCATCTCGCGAGGATGACGGAGCTTTAAGTAATACCATCTGGCATCCACTGAGCAGTATCAAGATggaaaacaatcaaaatgaGAGCATTGGCAATCAGAGCGAGAAGGAGCAGGAAGATAATGGAGGCGTGGATGTAGACGCCGAACCTGAGGCAGGAGCCGAGGAGTCGGAATTCCAAGGCGTTGAGAAATAG
Protein Sequence: MCSIFRNRINYRSTGTRSGSSNGGSSVGADTTGDSSLLAKELNADSNNNGSAADEMPEPEAALQLESETSLPCADQPENSNEALDLSVISGSRLPTSGHVALEALQHTKVAVAQFAATALAGTTDPNDLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAGGVVAALSRPGQSYAEPEDEEDEEDEEEPPPPPLNPSKEQPKLNGEEAEIDHERLEESSKTDEQEMSMEIEAISNECNREREVLLTKIEREREIEVEAERELESEYKPIMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFHCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPVVNGGPPPATPEQFAALPPIRLPFVTPAPLAPPPPPTVGQPSGDHTPLEQQQQEPQSLAMSGHLQQAEDLSKPAREMSHSPMQPAQTSKSLPERSRNQSATESVQPPVVFTEKQEKDKTKDSPKPTTPPTTANRRNGSVRKRQTSNAGSPPGDDREHPEHLQMAKLVRRSSASRDGTVALPGEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGNQGHGQSQSQSIGLGDAERLGIEDQNSNKSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATLLDRDRRTGHDDDRSRSDLEGGGRESTSGEMPAMDLSSPSSSSAATAAAARLFGVGNSTTAVGTGALPMLGMPMPPNLLLMAAARDEMHALGQTHAKFPLLPFGPLGLMGLQPPPNVCNLCFKMLPSQAALETHLQNEHAKEMTVPSARAHSNETISPYGAKLTLNPNLFAKKPKQSQEMAPAEPVTPSAAPIKEEPESDRLLVDEGGDNASNTAATNYQHETAADAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPSSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPAPGAAHGAPSAEQEFMQRRPELFFPYLPPFFNGIPPKPGELSPGAFTNIPPPHFANGAKYPYPPGLLSFPNFLGGAGLHHQYAHGVERSNSKSPTSEPAQSPASREDDGALSNTIWHPLSSIKMENNQNESIGNQSEKEQEDNGGVDVDAEPEAGAEESEFQGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00475377;
90% Identity: iTF_00617065;
80% Identity: -