Basic Information

Insect: Drosophila novamexicana
Gene Symbol: -
Assembly: GCA_003285875.3
Location: NW:5791210-5795566[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 29 1.1e-07 6.1e-06 25.9 1.1 1 23 144 166 144 166 0.98

2 29 1.6e-06 8.5e-05 22.3 3.8 1 23 172 194 172 194 0.98

3 29 0.046 2.4 8.3 4.3 1 23 200 222 200 222 0.97

4 29 2.1e-05 0.0011 18.8 1.4 1 23 228 250 228 250 0.99

5 29 3.9e-06 0.00021 21.1 0.2 1 23 331 353 331 353 0.98

6 29 0.00063 0.033 14.2 1.4 1 23 359 381 359 381 0.97

7 29 0.0081 0.43 10.7 5.3 1 23 387 409 387 409 0.97

8 29 0.0084 0.45 10.6 4.9 1 23 415 437 415 437 0.99

9 29 2e-06 0.0001 22.1 0.7 1 23 518 540 518 540 0.98

10 29 1.1e-07 6e-06 26.0 1.8 1 23 546 568 546 568 0.99

11 29 0.13 7 6.9 4.0 1 23 574 596 574 596 0.96

12 29 0.0084 0.45 10.6 4.9 1 23 602 624 602 624 0.99

13 29 1.2e-06 6.5e-05 22.7 0.1 1 23 714 736 714 736 0.98

14 29 0.00063 0.034 14.2 1.3 1 23 742 764 742 764 0.97

15 29 0.4 21 5.3 3.7 1 23 770 792 770 792 0.93

16 29 0.00073 0.039 14.0 0.6 1 23 798 820 798 820 0.98

17 29 1.2e-05 0.00063 19.6 1.5 1 23 901 924 901 924 0.97

18 29 0.00032 0.017 15.1 1.8 1 23 930 952 930 952 0.97

19 29 6.1 3.3e+02 1.6 2.9 1 11 958 968 958 980 0.72

20 29 0.015 0.82 9.8 8.8 1 23 986 1008 986 1009 0.96

21 29 5e-07 2.7e-05 23.9 1.3 1 23 1043 1065 1043 1065 0.98

22 29 1.9e-05 0.001 19.0 5.2 1 23 1071 1093 1071 1093 0.98

23 29 0.97 52 4.1 5.9 1 21 1099 1119 1099 1121 0.93

24 29 0.0015 0.08 13.0 7.4 1 23 1127 1149 1127 1150 0.96

25 29 1.8e-05 0.00094 19.1 1.5 1 23 1230 1252 1230 1252 0.97

26 29 0.034 1.8 8.7 3.8 1 23 1258 1280 1258 1280 0.88

27 29 8.6 4.6e+02 1.1 2.9 2 23 1287 1308 1286 1308 0.86

28 29 5.5e-05 0.0029 17.5 1.7 1 23 1314 1336 1314 1336 0.98

29 29 2.8e-06 0.00015 21.6 1.9 1 23 1416 1438 1416 1438 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	29	1.1e-07	6.1e-06	25.9	1.1	1	23	144	166	144	166	0.98
2	29	1.6e-06	8.5e-05	22.3	3.8	1	23	172	194	172	194	0.98
3	29	0.046	2.4	8.3	4.3	1	23	200	222	200	222	0.97
4	29	2.1e-05	0.0011	18.8	1.4	1	23	228	250	228	250	0.99
5	29	3.9e-06	0.00021	21.1	0.2	1	23	331	353	331	353	0.98
6	29	0.00063	0.033	14.2	1.4	1	23	359	381	359	381	0.97
7	29	0.0081	0.43	10.7	5.3	1	23	387	409	387	409	0.97
8	29	0.0084	0.45	10.6	4.9	1	23	415	437	415	437	0.99
9	29	2e-06	0.0001	22.1	0.7	1	23	518	540	518	540	0.98
10	29	1.1e-07	6e-06	26.0	1.8	1	23	546	568	546	568	0.99
11	29	0.13	7	6.9	4.0	1	23	574	596	574	596	0.96
12	29	0.0084	0.45	10.6	4.9	1	23	602	624	602	624	0.99
13	29	1.2e-06	6.5e-05	22.7	0.1	1	23	714	736	714	736	0.98
14	29	0.00063	0.034	14.2	1.3	1	23	742	764	742	764	0.97
15	29	0.4	21	5.3	3.7	1	23	770	792	770	792	0.93
16	29	0.00073	0.039	14.0	0.6	1	23	798	820	798	820	0.98
17	29	1.2e-05	0.00063	19.6	1.5	1	23	901	924	901	924	0.97
18	29	0.00032	0.017	15.1	1.8	1	23	930	952	930	952	0.97
19	29	6.1	3.3e+02	1.6	2.9	1	11	958	968	958	980	0.72
20	29	0.015	0.82	9.8	8.8	1	23	986	1008	986	1009	0.96
21	29	5e-07	2.7e-05	23.9	1.3	1	23	1043	1065	1043	1065	0.98
22	29	1.9e-05	0.001	19.0	5.2	1	23	1071	1093	1071	1093	0.98
23	29	0.97	52	4.1	5.9	1	21	1099	1119	1099	1121	0.93
24	29	0.0015	0.08	13.0	7.4	1	23	1127	1149	1127	1150	0.96
25	29	1.8e-05	0.00094	19.1	1.5	1	23	1230	1252	1230	1252	0.97
26	29	0.034	1.8	8.7	3.8	1	23	1258	1280	1258	1280	0.88
27	29	8.6	4.6e+02	1.1	2.9	2	23	1287	1308	1286	1308	0.86
28	29	5.5e-05	0.0029	17.5	1.7	1	23	1314	1336	1314	1336	0.98
29	29	2.8e-06	0.00015	21.6	1.9	1	23	1416	1438	1416	1438	0.96

Sequence Information

Coding Sequence: ATGGAATCCGcaataaaaatggaaatgccAGAGGAAGAGATAGACATAGTTCGGCTCGGGATGGATATAGAAGAATTGTTGAGCCCTGGGAATGAATTGCCCGAGGATCAAATGGAATACATGTCCGAAGATGAATGCAAAGCAAATACACCCATAGGTAATTTCAGTTCTCGGGATGTTAATCAAAGACAGTCTAGCCTACTGCTCGATAACACAAATCTAAGCAACAGCGAGCTTAGTGTCCGGTCCGAGCTGCTTGAAATAGAAAACTGGGAGCTGGCCGAGCAAGATAAAGATATAGGCTGCAGCAAAGAAGTAAAGGATAGTTTAAAAAACATTGAGGAGGAACAAACTGAACTAAGCTTACACAGCTACAAAGAATGCACTATTGCTGCTAACGAGCCTAAAATAGAtgctaacaaaacaaaatttatgtgcCCACAATGCCCAAAAGCCTATAAGAATAAATCTACCCTCAAATCGCACATTCGTACGCATACGTGCGAACGACCATTTCAGTGTCCACATTGCCCCAAAGCCTTTAAACAGTCCATGCATCTGCGCAACCACATATCTAATCATGAGGGGAAAGCTGCCTTTAAGTGTCCGCACTGCAGAAAATACTTTATAGAGAAAGCCAAGTACGATGAACACACGCGCTTTCATATTGGCCACCGGGCTTACAAATGTCTACACTGCCCAAAAATCTATACTACTATTTCAATGTTAAAAGAACACATTTTAACTCATAACGCAAATAACAGTGATGTAAATGTCCAGTCTGAACGGGTTGAAATAGAAAACTCGGAGCTGGCCGGGCAAGATAATGAAATAGGCTGTACCGAAGAAGTAAAGAATAGTTTAAAAACTATGAACGAGAAACAAGCTGAACCTAGCTTAAAAAGATACGAAGAATGCACCGTGAAGCACCAGGAAGTTTTCAATCCTCTTGCTGTTGACGAGCCTAGAATAGATGctaaaaagaaacaatttatatGCCCACAATGCCCAAAAGTCTATAAGAATATATCTAGCTTCAATGTTCACATTCGTATGCATTCGAGCGAACGACCATTTCAGTGTCCACATTGCCCcaaatcatttaaaatattcgGGATTCTGCGCTCCCACATATCTACCCATAAGGGGAAAACTGTCTTTAAGTGTCCTCACTGCAGAAAATTCTTTTCAGAGAAAGCCAAGTTCGATGAACACACGCGCTTTCATATTGGCCACCGGGCTTACAAATGTCTACACTGTCCAAAAATCTATACCCatattacatttttcaaaGAACACATTTTAACTCATTCCGCAAATAACAGCGATGTAAATGTTCAGTCCGAGCTgcttgaaattgaaaactcGAAGCTGGCCGAGCAAGATAATGAAATAGGCTGCAGCAAAGATGTAAAGGATACTGAAGTAACTATTAAGGAGGAACAAACTGAACTAAGCTCAAACAGCTACGAAGAATGCACCGTGGAGCGCTACGAAATTGGCAATCCTCTTGCTGTTGACGAGCCTAGAATAGATGCTGAAAAGGAACAATTTATATGCCCACAGTGCCAAAAGGCCTATAAGAATACATCTAGCCTCAATGTTCACATTCGTAAGCATTCGAGCGAACGACCATTTCAGTGTCCACATTGCCCCAAATCATTTAAAGTGTCCGAGAATTTGCGCTCCCACATATCTACTCATAAGGGGAAAACTGTCTTTAAGTGTCCTCACTGCACTAAATTCTTTTTAGAGAAAGCCCAGTACGATGAACACACGCGCTATCACATTGGCCACCGGGTTTACAAATGTCTACACTGTCCAAAAATCTATACccatattacattttttaaagaaCACATTTTAACTCATTCCACAAATAACAGTGAGGTAAATGTCCAGTCTGATCGGGTTGAAATAGAAAACAACGAGCTGGCCGGGCAAGATAATGAAATAGGCTGCAGCAATGAAGATAATGAAATAGGCTGTACCGAGGAAGTAAAGAATAGTTTGAAAAGCATTAAGGAGGAACAAACTGAACTAAGTTCAAACAGCTACGAAGAATGCACCGTGGAGCACCACGAAGTTTGCAATCCTCTTGCTGTTAATGAGCCTAGAATAGAtgataaaaagaaacaatttatatGCCCACAATGCCCAAAAGTCTATAAGAATATATCTAGCCTCAATGTTCACATTCGTATGCATTCGGGCGAACGACCATTTCAGTGTCCACATTGCccaaaatcatttaaaatattcgcGATTCTGCGCTCCCACATATCTACCCATAAGGGAAAAACTGTCTTTAAGTGTCCTCACTGCAGAAAATTCTTTTTAGAGAAAGCCGAGTACGATGAACACACGCGCTTTCATATTGGCCACCGGGCTTACAAATGTCTACACTGTCCAAAAATATTAGTTAATATTTCATCATTTAAAGCACACATTTCAATTCATCCCACAAATAACAGTGAGGTTAATGTCCAGTCTGAACGGGTTGAAATAGAAAACTCCGAGCTGGCCGGGCAAGATAATGAAATAGGCTGCAGCAATGAAGTAAAGGATAAGGAGGATATCATTGAAGAGGAACAAACTGAAATAAGCTTAGAGAACTACGAAGGATGCACCGCGGAGCGCTACGAAATTAGCAATCCTCTTGCTGTTGAGGAGCCTAGAATAGATGctaaaaagaaacaatttatatGCCCACAGTGCCAAAAGGCCTTCAAGACCAAATTTATGCTCACAAGTCACTTAAGTACGACGCATTCGGATGAACGACCATTTCAGTGTCCACATTGCCCGAAAGCATTTAAAAGATTCGGGATTCTCCGCTCACACGTATATACTCATAATAGGACAACTGCCTTTAAGTGTCCTCACTGCAGAAGATACTTTTTAGAGAAAGCCAAGTACGATGAACACACGAGCTTTCATGTTGGGCACCGGCTTTACAAATGTCCGCAATGTTCAAAAATCTGTACTCATTATACAAGGTTTAAAAACCACATTCGAATTCATCACGCAAACAACAGTGAGGGACAAACTGAACTAAGCTTCAAGAGCTACGACGAATGCACGACTGCTGTTAACGAACCTACAATAGatgctaaaaaaacaaaatttatatgccCACAATGCCCTAAAgcctataaatataaaactagCCTCAAATCGCACATGCGTACGCATACGTGCGAACGACCATTTCAGTGTCCACATTGTCCCAAAGCCTTTAAACAGTTCATGCATCTGCGCAACCACATTTATAAACATAAGGGGAAAACTACCTTTAAGTGTCCGCACTGCAGAAAATACTTTATAGAGAAAGCCAAGTACGATGAACACACGCGCTGTCACATTGGCCACCGGCTTTACAAATGTCCACACTGTTCAAAAATCTGTTCTGATCAGACAAGGTTTAAAAAACACATTCTAATTCATCACGCAAACAACAGTGAGATAAATGTCCAGTCCGAGTTGCTTGAAATAGAAAACTGGGAGCTGGCCGAGCAAGAGAATCAAATAGACTTCAGCAAAGAAGTAAAGGATAGTGAAGTTAACATTAAGGAGGAACAAACTGAACTAAGCTCAAACAGCTACGAAGAATGCACCGTGGAGCGCTACGAAATTGGCAATCCTCTTGCTGTTGACGAGCCTAGAATAGATGCTAAGAAGAAACAATTTATATGCCCACAGTGCCAAAAGGCCTGTAAGAATACATCTAGTCTCAATGTTCACATTCGTTTGCATTCGAGCGAACGACCATTTCCGTGTCCACATTGCccgaaaacatttaaaacgttCTGGATTTTGCGCTGCCACATATCTACTCATAAGGGGAAAACTGCCCTTAAGTGTCCCCACTGCAGAAGATACTTTTTAGAGAAAGCCAAGTACGATGAACACACGCGCTTTCATATTGGCCACCGGGCTTACAAATGTCTACACTgtccaaaaatatttactaCTATTTCATTCTTTAAAGCACACATTTTAATTCATCCCACAAACAACAGTGAGGTTGATGTCCAGTCTGAACGGGTTGAAATAGAAAACTCCGAGCTGGCCGGGCAAGATAATGAAATAGGCTGCAGCAATGAAGTGAAGGATAAGGAAGATATCATTGAAGAGGAACAAACCGAAATAAGCTTACAGAACTACGAAGAATGCCACGAGCGCCACGAAATTTGCGATCCTCTTGCTGTTGACGAGCCTAGAATAGATGctaaaaagaaacaatatttatgcCCACAGTGCCAAAAGGCCTTCAAGACCAAATTTATGCTCACAAGTCACTTACGTACGCATTCGAACGAATGA
Protein Sequence: MESAIKMEMPEEEIDIVRLGMDIEELLSPGNELPEDQMEYMSEDECKANTPIGNFSSRDVNQRQSSLLLDNTNLSNSELSVRSELLEIENWELAEQDKDIGCSKEVKDSLKNIEEEQTELSLHSYKECTIAANEPKIDANKTKFMCPQCPKAYKNKSTLKSHIRTHTCERPFQCPHCPKAFKQSMHLRNHISNHEGKAAFKCPHCRKYFIEKAKYDEHTRFHIGHRAYKCLHCPKIYTTISMLKEHILTHNANNSDVNVQSERVEIENSELAGQDNEIGCTEEVKNSLKTMNEKQAEPSLKRYEECTVKHQEVFNPLAVDEPRIDAKKKQFICPQCPKVYKNISSFNVHIRMHSSERPFQCPHCPKSFKIFGILRSHISTHKGKTVFKCPHCRKFFSEKAKFDEHTRFHIGHRAYKCLHCPKIYTHITFFKEHILTHSANNSDVNVQSELLEIENSKLAEQDNEIGCSKDVKDTEVTIKEEQTELSSNSYEECTVERYEIGNPLAVDEPRIDAEKEQFICPQCQKAYKNTSSLNVHIRKHSSERPFQCPHCPKSFKVSENLRSHISTHKGKTVFKCPHCTKFFLEKAQYDEHTRYHIGHRVYKCLHCPKIYTHITFFKEHILTHSTNNSEVNVQSDRVEIENNELAGQDNEIGCSNEDNEIGCTEEVKNSLKSIKEEQTELSSNSYEECTVEHHEVCNPLAVNEPRIDDKKKQFICPQCPKVYKNISSLNVHIRMHSGERPFQCPHCPKSFKIFAILRSHISTHKGKTVFKCPHCRKFFLEKAEYDEHTRFHIGHRAYKCLHCPKILVNISSFKAHISIHPTNNSEVNVQSERVEIENSELAGQDNEIGCSNEVKDKEDIIEEEQTEISLENYEGCTAERYEISNPLAVEEPRIDAKKKQFICPQCQKAFKTKFMLTSHLSTTHSDERPFQCPHCPKAFKRFGILRSHVYTHNRTTAFKCPHCRRYFLEKAKYDEHTSFHVGHRLYKCPQCSKICTHYTRFKNHIRIHHANNSEGQTELSFKSYDECTTAVNEPTIDAKKTKFICPQCPKAYKYKTSLKSHMRTHTCERPFQCPHCPKAFKQFMHLRNHIYKHKGKTTFKCPHCRKYFIEKAKYDEHTRCHIGHRLYKCPHCSKICSDQTRFKKHILIHHANNSEINVQSELLEIENWELAEQENQIDFSKEVKDSEVNIKEEQTELSSNSYEECTVERYEIGNPLAVDEPRIDAKKKQFICPQCQKACKNTSSLNVHIRLHSSERPFPCPHCPKTFKTFWILRCHISTHKGKTALKCPHCRRYFLEKAKYDEHTRFHIGHRAYKCLHCPKIFTTISFFKAHILIHPTNNSEVDVQSERVEIENSELAGQDNEIGCSNEVKDKEDIIEEEQTEISLQNYEECHERHEICDPLAVDEPRIDAKKKQYLCPQCQKAFKTKFMLTSHLRTHSNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -