Dniv002130.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila niveifrons
Gene Symbol
-
Assembly
GCA_035046325.1
Location
JAWNOC010000020.1:6616892-6625928[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.074 4.8 7.8 0.4 1 23 592 614 592 614 0.96
2 7 0.36 23 5.6 0.6 2 19 619 636 618 637 0.97
3 7 6.7e-06 0.00044 20.5 0.3 1 23 643 665 643 665 0.99
4 7 0.0034 0.22 12.0 4.2 1 23 675 697 675 697 0.98
5 7 0.0008 0.052 14.0 0.1 2 23 704 725 703 725 0.95
6 7 1.2e-06 8e-05 22.8 1.3 1 23 731 753 731 753 0.98
7 7 9.3e-05 0.006 16.9 3.5 1 23 759 781 759 781 0.98

Sequence Information

Coding Sequence
atggccagcatcaacatcaacaacaacaacatcatcagcattagCAGCAGTAtaacaaatgcaacacaagcaacagcaacaacaacaacaacgctgcCATCGCTGTttaacggcaacaacaacaacaacaacatctgcaacactggcagcagcaacaacaataataacaacaacaacaacaacgtaaaCGTTGCCGCCAAAGATATGGACGGACTGATTGCCATCAATGATAGCGCATTATCGCAACAAATCGAATTTATACTACAAGATGCTCCCATGGAGCAGGATgacgagcagcaacagttgcagctgcaacagcagctccacATGGCGGCGTCCAAGCTCGACAACCACCCACcgacaacaaatgcaacaataacgacaacagcaacaacagccacagcagcaaccacaacaaacaacagcgcTTCCCCatacattaacaacaacagcatcatcagcaacaacaacaacacgaacaacaacagcaactgcagcagcaacagcaatcacagcagcaacaacagtctAAGCGTTGAACATgatcaacagcaactgttgctgcaacaacatcgcgcacaacagcagcagcaacagcaacatcatctgCTCAATGGACGTCGCATCATTATACAATCAACAACTTGTGGCAGCGGTGGCAACTCTGTTCTCTCGGCCAGCGACATTAAGGAGGAGCAACTGGAGcaagacgatgacgatgatgatgaacagcagcatcagcaacagcacataacgcaacagcagcatcatcatcatccgcatccgcatcatCAGCGTCTTCATCATGCAGACGAGGACGATGAgggcgaggaggaggaggaagaagatCCCGAATTGAACGATGAGAATCTGCAGGACATTGAGGAGGAGGCGCAGGCAGCCGAAGCCGATGAGGAGCCCGAAACGGCGGCAACCACACATTTGCAACATACGCAAACGCATCTGCATCATCATCcgcatcatcaacagcagcaacagcaacatcatccacaccaacagcagcagcagcaattgcaacagcagcagcagcaacaacaacaactgcagcaacatttgcagACTCAGGTGAAGTTGGAGCTGAATGAGCTGCCCGATGACGAGGAGGACGATGaggaggacgaggacgaggatgAGCACATGGCAACGCAGTCGACAAcagcgcaacaacagcaactcgagacgctgcaacagcaactggagtACACGACGGGGACACAGCAGCTGGTGTTGCCAGCCGGAAGCATTGTGAGCACCACAACGCGCGCTTTGGCGGTGCCTGTGTCGGAGGCAGCATTGGTGCAGCTGCAACGTCGTCCCGTGTACATCAGCAATGCGACAATGAGCAGTTTGGCTGGTGCCACATATGTGCGAATGCCGGCAGCGGCGGTGATTAGTCGCAGTCCGATGACGGTGCTCAATGTGGTGCAACAGACGGGCGGACCGACGGCTCAGCTTATATTgcaggcggcggcagcagcagcagcgccacagcagcaacagcaatcaactgctggtgcagcagcaaccgctgcagcaacgacagcagcaacagttgctacGCCATCGCCCAGCAATGAGCAACAATTGGCGGCCATAGCgcttgcccagcagcagcagcaacaacaacagcaacaacaacagcaacaacaacagcagcagcagcaacaacagcagcagcagcagcagcagcaacatcatcagtcCATTAAACCAGCGCCAGCCACAAGCAATGTGGCAACATCGACGACCAGCTATCAGTGCATGGAATGCGTGGAAAAGTTCGATTCGAAGGAACTGTTTGACATCCATCGCAGCGGGCACGCGAACAACATGAAATGCGCCATCTGCAACATGGTCCTCAAATCGCTGAAGAACTATGAGAAGCATTGTTTGCGCTGCAAGCCCTACGAATGCCAGATCTGTGGACGTGTTGTCCGCTTTCGTCCCAATTTCATCAAGCATATGCGCGTCCACACCGGCCAACAATCGGAGcggcacaaatacaaatgcgagGTCTGCCACAAGGAGTTCATGAGCTTTGAGTACTTCAAGGTCCACAAGAAGATCCACAACGAGAATGTGAATCTCACCTGCGAGATCTGTGGCAAGGTGTTCAGTGCCCTCGCCTCATTGCGCGGCCACTCCAAGCTCCATTCGGGCGTCAAGCTGCACAAATGCGATGTGTGTGGCAAGGGCTTTGGACAGCGCTACAATCTGAAGATTCATGCGCGCACACACACCGGCGACTTTCCCTTTGAGTGCAAAGTGTGCAAGAAGAAGCTGCACACGCAATCGTCGCTGCAGACACACATGCAGGTCCATCTGCGCGATCAGCCCAAGAacggtagcagcagcaacagcagcagcaacaacaacaacaacaacaatagcagcagtagcagcagcaacaacagcgccgccagcagcaacaacaacagcagcagcggcagcaacaacaacaacaatgcagcaaCTGTTAAAATCGAACCCgatttgcagcagcaacatcaccaacaccaacagcagcagcagcagcaacagttgcagtcaCATGAAATGGAGCTGGACGAACAGTCGGGCTTGAGTGAGGATGAACACgatggtgttgttgctgctgtcgctgtggcTGGTTCGCTGCAGAATTCGTTGACCAATAACAATCGCTTAACCaccggcggcggcggcgaggATTCCTCAAATGAATCCTCCTCGAATGCCTCGCTACAACAGCCGCACTCGAATTCGGCCAGTTCATCGCAACActcgcaacagcaacaacagcagcagcagcaacaacaacaacaatatattgTTGCGCCGCCGCGTTCAATTGTCATCAAGAACTatatgcaacaacagcaacaggcaccGGTGATAGATGCCGCAAGCGGTGGCAATTGCTCGAGTGTGCTGCACACACAGGTCATACAGAGCGGTGCaggcaccagcaacagcaatggcaacggcaacggcaatcaCATcaacagtcacagcagcagcaacaccagcagccagaacagcagcagcaacagcagcggcagtggcGGCAACACAAACAGTAGTCAGCATGGCAACAGCATGCACAGCATCAACAATGGCCACACgaatcacagcaacaacagcagcagcggcagcattgttgctgccgcaacagcagccacgGTTGCTGGCAGTGCGGCGAGCAGCAATCTGGCTCAGCAGTTGCTGCGCAAAACTCCCATCATACACTCGACGGGCACGCTAAGCTCAGCGTTGGCCAGCGTTGTTCAACAGACGGGCGTTGGTTCGCCGGCGCaatcgccatcatcatcatccacatcGTGTTCCTCCTCCACCGTGCTGGTGTCCAAGGCGACGGGAGTGCCGCTATCGATTGCCTCATCGGCGGCACTGGGCGGCTCCACAATAATACGCAGCACGCGCAaccatcatcaacagcagcagcagcagcaacaggcggcGGCGCAGAGCAATCAGCAACGTGTTGTCGcgggacaacaacagcaacagcagcgtaaTAACCACCGAAATCACCACCGACGTCGTCATTTGGCGGACAtggatgacgatgatgatgatgatgatgatgacgatgacaatgaTAATGAGGATGAGACGAgcgtgcaacaacaaatgcgtgcagttgctgctgcaaccaCAAACggacatcatcagcaacagcagcagcagcaacagttgtcaCAGCACTCGTCGAATCATAATCATAGTCACAgtcatcaacatcagcaacagcaacaacaacaagcgaacaatcatcagcagcaacagcacaacagcaacaaccatcagcagcagcagcagcaacatgcgttgcatcatcatcatcatcatcaccatcatcacaATCATCACAATCAtttcgatgatgatgatgacgatgagaaATCATCACCGTCCCTGGCAACAGCCGCAATCATCAAAGTCGAACCGAATCTCTATTCATCCGGATCGGGTGACAATTCCAACGATATGTTCATCAAGGAGGAGGTGATGTTTGAAGATTCCGCTGCACCGCATTCACCACAATCGCCGCCCAGCTCGAAATTTCGTATCTCGAATTTCGACAGCGATCTCGTCGATGATCATGTCGATCTAAATCATTCGCTGCCACCGTACGGTAATCTCTTTGAACCGCACTCAATACGCGACAGCATCCCAGTGCAATTGTATcccgatgacgatgatgatttTCGCTTGGATCACAGTTCGCTGGGTGGCCTACACAATACATCGTCGTCGACCACCGATGGGGATTTCATCAAAAAGGAATGGGTCTATGGCAGTGCATCGAGTAGTTATGCCATGAATGGTAAATTCGATGATGATAGCGATGCTCTCTGCGATGCCGccaatttcatttacaattaa
Protein Sequence
MASININNNNIISISSSITNATQATATTTTTLPSLFNGNNNNNNICNTGSSNNNNNNNNNNVNVAAKDMDGLIAINDSALSQQIEFILQDAPMEQDDEQQQLQLQQQLHMAASKLDNHPPTTNATITTTATTATAATTTNNSASPYINNNSIISNNNNTNNNSNCSSNSNHSSNNSLSVEHDQQQLLLQQHRAQQQQQQQHHLLNGRRIIIQSTTCGSGGNSVLSASDIKEEQLEQDDDDDDEQQHQQQHITQQQHHHHPHPHHQRLHHADEDDEGEEEEEEDPELNDENLQDIEEEAQAAEADEEPETAATTHLQHTQTHLHHHPHHQQQQQQHHPHQQQQQQLQQQQQQQQQLQQHLQTQVKLELNELPDDEEDDEEDEDEDEHMATQSTTAQQQQLETLQQQLEYTTGTQQLVLPAGSIVSTTTRALAVPVSEAALVQLQRRPVYISNATMSSLAGATYVRMPAAAVISRSPMTVLNVVQQTGGPTAQLILQAAAAAAAPQQQQQSTAGAAATAAATTAATVATPSPSNEQQLAAIALAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQSIKPAPATSNVATSTTSYQCMECVEKFDSKELFDIHRSGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRVVRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALASLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKVCKKKLHTQSSLQTHMQVHLRDQPKNGSSSNSSSNNNNNNNSSSSSSNNSAASSNNNSSSGSNNNNNAATVKIEPDLQQQHHQHQQQQQQQQLQSHEMELDEQSGLSEDEHDGVVAAVAVAGSLQNSLTNNNRLTTGGGGEDSSNESSSNASLQQPHSNSASSSQHSQQQQQQQQQQQQQYIVAPPRSIVIKNYMQQQQQAPVIDAASGGNCSSVLHTQVIQSGAGTSNSNGNGNGNHINSHSSSNTSSQNSSSNSSGSGGNTNSSQHGNSMHSINNGHTNHSNNSSSGSIVAAATAATVAGSAASSNLAQQLLRKTPIIHSTGTLSSALASVVQQTGVGSPAQSPSSSSTSCSSSTVLVSKATGVPLSIASSAALGGSTIIRSTRNHHQQQQQQQQAAAQSNQQRVVAGQQQQQQRNNHRNHHRRRHLADMDDDDDDDDDDDDNDNEDETSVQQQMRAVAAATTNGHHQQQQQQQQLSQHSSNHNHSHSHQHQQQQQQQANNHQQQQHNSNNHQQQQQQHALHHHHHHHHHHNHHNHFDDDDDDEKSSPSLATAAIIKVEPNLYSSGSGDNSNDMFIKEEVMFEDSAAPHSPQSPPSSKFRISNFDSDLVDDHVDLNHSLPPYGNLFEPHSIRDSIPVQLYPDDDDDFRLDHSSLGGLHNTSSSTTDGDFIKKEWVYGSASSSYAMNGKFDDDSDALCDAANFIYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509396;
90% Identity
iTF_00554021;
80% Identity
-