Basic Information

Insect: Drosophila niveifrons
Gene Symbol: -
Assembly: GCA_035046325.1
Location: JAWNOC010000070.1:2679307-2683254[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00043 0.028 14.8 0.1 1 23 169 192 169 192 0.96

2 14 0.0017 0.11 12.9 3.1 2 23 241 263 237 263 0.89

3 14 0.065 4.2 7.9 0.8 1 23 352 375 352 375 0.92

4 14 0.25 16 6.1 3.2 2 23 424 446 423 447 0.95

5 14 0.0034 0.22 12.0 0.5 1 23 512 535 512 535 0.88

6 14 7.9 5.1e+02 1.4 0.0 2 13 554 565 553 570 0.81

7 14 0.00072 0.047 14.1 3.3 2 23 586 608 586 608 0.96

8 14 0.0011 0.071 13.5 0.1 1 23 705 728 705 728 0.95

9 14 0.00011 0.0073 16.6 0.2 1 23 789 812 789 812 0.92

10 14 0.0012 0.079 13.4 2.2 2 23 862 884 861 884 0.97

11 14 0.0019 0.13 12.8 2.0 1 23 977 1000 977 1000 0.92

12 14 0.055 3.6 8.2 1.5 1 21 1052 1072 1052 1073 0.95

13 14 1.1 74 4.0 0.1 2 23 1127 1151 1126 1151 0.83

14 14 1.7 1.1e+02 3.5 0.6 1 16 1169 1183 1169 1193 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00043	0.028	14.8	0.1	1	23	169	192	169	192	0.96
2	14	0.0017	0.11	12.9	3.1	2	23	241	263	237	263	0.89
3	14	0.065	4.2	7.9	0.8	1	23	352	375	352	375	0.92
4	14	0.25	16	6.1	3.2	2	23	424	446	423	447	0.95
5	14	0.0034	0.22	12.0	0.5	1	23	512	535	512	535	0.88
6	14	7.9	5.1e+02	1.4	0.0	2	13	554	565	553	570	0.81
7	14	0.00072	0.047	14.1	3.3	2	23	586	608	586	608	0.96
8	14	0.0011	0.071	13.5	0.1	1	23	705	728	705	728	0.95
9	14	0.00011	0.0073	16.6	0.2	1	23	789	812	789	812	0.92
10	14	0.0012	0.079	13.4	2.2	2	23	862	884	861	884	0.97
11	14	0.0019	0.13	12.8	2.0	1	23	977	1000	977	1000	0.92
12	14	0.055	3.6	8.2	1.5	1	21	1052	1072	1052	1073	0.95
13	14	1.1	74	4.0	0.1	2	23	1127	1151	1126	1151	0.83
14	14	1.7	1.1e+02	3.5	0.6	1	16	1169	1183	1169	1193	0.75

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACATCCATGTTTTCGGCTGATTTTGAGGAGGGCGATGATGTGATTGACAATTATAATATTGGTAACAACGCAGACGAGTTTATTGgggaagaagaggaggagcaaGAGGCTGATATCGATGAGATAGACGAAGACAGGGAAGTGGAGCAGGACAGGGAGGAGAGAACGCGAAAGCAGAAGGGAAATGAGCCCGATGATGATGCGATATTTGATTTCGAAATGGAACCCATTATTAGCATTGCTGAACCGGAATTGGAACCACCTGTGCGTCGCGAAACTGTCGCCTTGGTACCACCAATGGCAACCGCTGGGCCACCGGTGCGTGGCGTGCACCGTCAGTCGCTTCCCGCATCGTTTGGTTCCTCGTTGATGCCACGAGGAGGGTCTGTGGTGGCAGCAACACCGCCAACACGTCCAACAACATCGCAGATCAATGCCACCGATGAGAATGGCGTACCCATTAATTATGAATTGGGTGTCATTTACATTTGTCCCGCATGCGGGGCGGAGTATCGACAGCAGGACATGTGGAAGCGACACATGAACCAGATGCATCAGTATAACACACGCAAGGGTCTCAATTTTGTGGCCATTGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGAATTGCGATGCACAGTCGAGAGAATCTCTTGAAACACAAGTTTACACATTTGCCGTATCGTTGCACTAAGTGCTTCATCTGTAAACGAGAGTACAAATACAGGCAGGACCTAATGGTGCATCTGCGCATGGTTCACTGCGACGAGGTGGTGACCATGATGCGTGATGGCGACACTAGTGCGGGGCGTAAGACACGTGTGCGCGAGCCACGCACCGAGCAACCAAGAGCGCCGAGctacgacgatgacgacgttAAGCATGTGGAGCTAGTGGAGACAGAGGCGGATGCTATTGCTGCTGGAGAAGAGGTGGAGGAAAAGAGAAAGCATTGTAATCCAGCGGCGTCTGGCAATGGGAGCTGTGTGAGCAGTGCTGCTGAAATCTGCGAAGATTACATACACTATATGTGTCCTGACTGTGGAAACGATTGCGACACTCACGCACAGTGGAGTCAGCACATTGAATTCGTTCATGATTATGTCAGCAGACGAGGCCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTGGAGTGCAAGCAGTTTGTCATACCAAACACAATCAAGAGTTTACGAGCTCACAAATTTAGCCACTTGTCACAACCTAATTGGATGCGCTGCAAATTGTGCTATAAAGGCTACAAGGAGCACCAGGAGCTGGTGATCCATCTGCTTAAGCAGCATCACTTGGAGACATTAATGCCCGACGCCGAGGAAACGGATGAACCCCTGTGTAGTATCAGTGGCGGTGAAGTGAACGGCGAAGATAAATCTGCAACTGGCAATGACGGCGAGGAGGAATCGATAGCCCATTGGGACGAAGCACCACGTCGCGGCGGACGTATCAGCAGCGACGACATGTACGAGCCACACATTGACTATTTGTGTCCACAGTGCGGTCGTGAGTTCATCGAGAAGAAACACTGGCGAACACATGTCGTTCAAGTGCATGGCATGAACGATCTGAGCAAGTTGAACTTTGAGGTGATCAACGATCGTCAGCTGAAGTGCACAGAATGCGAGAAAATTATTACGAATGCATATGGCATACAGAATGCACAGCAGCACCGCATTACGCACTTGCCATACAAGGCCTATGCTCGCTGTCGAAAGTGCCATAAATCGTACACAGATCGCAAGGGGTTGGTCAAGCATTTGGCCACATATCATCGTGTTGGCTACGAGCCACGTAAAGCGGCTGCTGGAGCCGTATCCAGTAAGGTGCAGACGCCGCGTAAACAAATTGTCACCGTGGGAAATGAAACCTATGAGATTATCTATTTGGATGAAGAGCAATCGTCGCCAGGCAATAGTAACGTTAACGAAGAGAATGATTTTGGCGAACAGATGCAggcagatgatgatgactacGCCATCAGTAGTACTAATTATAGTAACAACAGCAGTCGTCAACTGTCATCAACTACCACGCCCACTCACTTTCATAATCCAAATCGTTACAAGTGCGTTGATTGCGGCTCGCTGTTTCCAACGCAGGCAGCGCTCAAGTCGCATATTAGCGAGGAGCATGATTTTATGGATACGCATTATAGTGCCAAAAAGTTCGACAACCCTGAACTGACTGATGAGTCAGCTCAGGTCCCGGCTTCAGCTTCCGTTCAAGCGGCTACAACAAAAACGTCTCCAGGTGCTAAGAAGTCATCACTATTGAATCCATCTGGCGCTTCAACTATTGAACAAAACTATATCTTCTTGTGCCCATCATGTGGCAAGGCTTACAAGACGCAGTTCGAGTGGCGTCGCCACATAAACGATGCTCACAATTTCGACAAACGTCAATACTTAAATATGCGCCAATTGGACAAGTATCGTTATCAGTGCACCCAGTGTAAAGATATTGTGAGCAGCTCGAAGCTAAAGGGTCTACAGGATCATCACTTTCGCCATCTGCCCTATCGCCTCTATCTGAAATGTCTCGTCTGCGGCACTTGCTACAATCACAAGCCGAACATCGCGGCTCATCTGCGTACGCGTCACAACATCTACGAACGTGATACGCCATGGCGTGAATTACAGCCGAAGCCACAGTACAACTATGTGATAATGAAAGACAAGgataaagagaaagaaaaggaagGTGGTAGTGGAATTTCCTTTAAGTCATCGTCGCCGATACCTGCCAGTAGCAGTAGCTGTAATGCAGGGCGTTCTCTAAAGCCGCAGCCAGGCGTACTGCCCACTCGACCCGCTGGACTGAATACGCTGGAGGACAGCATTTCATATCACAATGCTGTGGACTTGGATTTCATTACATACTATTGTCCTAAGTGCAATAAGAACTTTGATTCGCATGCGTTCTGGCGCAAACACATTGTTGAGCAGCACAATTACAACAGTCGTCAGGGTCTCAATTTTCGTCAGATCGATATTCATCATTATTTGTGCCTGGAATGCTACAAGCGTGTTACAGTTACCCACACCAAGGGTGCCATTGGTCAGTTGCAGTCCCATAAGTTCCGGCATCTGCCCTATCGATCCTTCAAGTGCCTGACCTGCAATGGCGAATTTGTGCGCAAACAAATGTTCTTCAAACACCTGAATCGTGATACAAATCGCTGCGACAACAAGCCTTTGAGTGCCCAGGAGACGGACGACGATGGTGTAGAGCCTACCGAGAGTTTGGTTAGCGGCGGTGGAGAAGATTGTTTAGTCCCAGCTGCTGCTAGTGCTTTAAACGAAGTTGATCCCGCTGCTTATCGCCTGATATGTCCTCAATGCGGTGATAACTTTAAGACAACCAGCAAAGGGCTATGGCGTGAACATATAAACATCTATCATGGCCTGGGCAAGCGAGAGCAGCTGCATATGCGCAAGATAGGCGAGGATCTTTATCGCTGCACAGACTGTGACGAGCAATTACAATCAAAGCATTTGCGGGTGCTGCAGGAACATCGCTTTCGCCATTTGCCCTATGCTCCGTACATTCGGTGTCAGGTgtgcgaaaaacaaaaagatgaaCTAGGTCTTGGAGCTGTTGCAGCTGGACTGCACAGTATGATCGAGTTACAGCAACACATTCGAGAGAAGCACCCCGAGTTGGCTAAGGGTGATGAGCGAATAGAATCGCTGTtagacgatgatgacgatgacgactaTCAGCATACGAACGATAAGACAGCAGGCAATGGACGATATATGCCGCTACCACCGCATTTACTAGACGACGATGGGGATGATGTGGAATTTGAAGATCAGTATCTACTAGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDDVIDNYNIGNNADEFIGEEEEEQEADIDEIDEDREVEQDREERTRKQKGNEPDDDAIFDFEMEPIISIAEPELEPPVRRETVALVPPMATAGPPVRGVHRQSLPASFGSSLMPRGGSVVAATPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCFICKREYKYRQDLMVHLRMVHCDEVVTMMRDGDTSAGRKTRVREPRTEQPRAPSYDDDDVKHVELVETEADAIAAGEEVEEKRKHCNPAASGNGSCVSSAAEICEDYIHYMCPDCGNDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKSLRAHKFSHLSQPNWMRCKLCYKGYKEHQELVIHLLKQHHLETLMPDAEETDEPLCSISGGEVNGEDKSATGNDGEEESIAHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLSKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAAAGAVSSKVQTPRKQIVTVGNETYEIIYLDEEQSSPGNSNVNEENDFGEQMQADDDDYAISSTNYSNNSSRQLSSTTTPTHFHNPNRYKCVDCGSLFPTQAALKSHISEEHDFMDTHYSAKKFDNPELTDESAQVPASASVQAATTKTSPGAKKSSLLNPSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVIMKDKDKEKEKEGGSGISFKSSSPIPASSSSCNAGRSLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQETDDDGVEPTESLVSGGGEDCLVPAAASALNEVDPAAYRLICPQCGDNFKTTSKGLWREHINIYHGLGKREQLHMRKIGEDLYRCTDCDEQLQSKHLRVLQEHRFRHLPYAPYIRCQVCEKQKDELGLGAVAAGLHSMIELQQHIREKHPELAKGDERIESLLDDDDDDDYQHTNDKTAGNGRYMPLPPHLLDDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556790;
90% Identity: iTF_00556790;
80% Identity: -