Basic Information

Insect: Drosophila niveifrons
Gene Symbol: PRDM1
Assembly: GCA_035046325.1
Location: JAWNOC010000052.1:9194579-9198926[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3e-05 0.002 18.4 2.5 1 23 895 917 895 917 0.99

2 5 9.1e-06 0.00059 20.1 5.1 1 23 923 945 923 945 0.98

3 5 1.9e-06 0.00012 22.2 4.3 1 23 951 973 951 973 0.98

4 5 0.00063 0.041 14.3 2.4 1 23 979 1001 979 1001 0.97

5 5 0.00011 0.007 16.7 0.1 1 22 1007 1028 1007 1028 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3e-05	0.002	18.4	2.5	1	23	895	917	895	917	0.99
2	5	9.1e-06	0.00059	20.1	5.1	1	23	923	945	923	945	0.98
3	5	1.9e-06	0.00012	22.2	4.3	1	23	951	973	951	973	0.98
4	5	0.00063	0.041	14.3	2.4	1	23	979	1001	979	1001	0.97
5	5	0.00011	0.007	16.7	0.1	1	22	1007	1028	1007	1028	0.96

Sequence Information

Coding Sequence: atgcaTGGACTTCATCAGCAtccacagcagccgcagtcggCGTCGCAGTCAACATCAGCGCAGCCAACGCCAGCCAGCATGAAGACAGCGAGCAAtgtccagcaacaacaacaacaacaacagcagcagcaacaacaacaacacatagCCATACAGCATCCACATGCGcatgcacacgcacacgcgCTAGCAAATCATCATCCACACCATCCACACCATCCACATCATCCACAACACCATGCGCATCCACAGCACGCTGCCAAGCTGTTGCGTCGCTcgcgcagtcgcagccgcagtcgcagcccAACGCCCGACGGCAGCCAAGACTACGATGTGACGCGCATGCGTGAAGAGGACTTTGAACGTTTGGCCGTTTATTTGGTGCCCGATGTGCAGGCAGAGCGAGGGTTGCCCAATCGGGCGGATAAAACGCTGCCGCGCAGTCTGACGTTAAAGTCCTCGATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTGATACCGCGTGGCACACGCTTTGGCCCTTTCGAAGGCATTCCAACCTCAAACTATCCAAATGATAAGAATAAGGCGCGATATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGATGATTACTATTATTTGGATGGCTCGGATCGCTCGCAGTCCAACTGGATGCGTTACGTGGCCTCCGCCTACAGTCTGCAGGTGATGAATCTTGTCGCCTGTCAGCATCAGGAGAACATCTATTTCTATACCACCCGCGATATTCTGCCCAACGAGGAACTGATGGTCTGGTACTGCAAGGACTTTGCCAGCCGCCTTGGCTACGATGTGGATCCCGAGCGCACCATTTTCGGTGCCTGCAAGCAGGACGTAGATGTGGAGgatgaggacgaggacgatgaACTGCCGCACAAGAAACCGCACTATGCCATGCCCGCTGCACCCGAAATTCCCGCCGAGGTGGCCGTCAGTCACATTACCTATGTGATGGGACTGCATCTGCCAGGCGCTGCACCCGCACCCGCTTCCTCAACCGCTGCCGCTCCCACTTCGGCTGCCTCCACGCAATGCTGCCGTCGCGGCAGTCCGCCTGCGCATGTCAGcaccacgacgacgacgccggcGACGACCCAAAGCGCACATCCGCACATACAGCATAGTCGACATGCGTCGGTCATCATCGGACAGGATCGTTCGCCGCTGAACAGCTGCAGTGACAAGGATAACGTCAACTCGGCGGTCTCGGAGCATCATTACGAACATCAGCTGACGCCGCAGGATGGCAGCGTGCGTTCGGTGCGCTCCGATGAGGGTTATCATAGTAACGAGTGCCAGGAGGATGGTCTGACGCCGCCCGAGGACTCGAGTGACAGCGAGAGCGAGCACAACTATGTGCTGGACTGCTCCAAGAAGGCGATTGCCCCGAAGGAAACGGTCATTGCGCAAGCACAAAAACCGAGCAGTGTGACGCCCCCAGCGCCCAGCACACCGCCACATGCGGCCACGCCCAGCAGTTGTCAGCCGGAAGCGGACAAGAACGAGTACCGCAAGTTCAAGGTAAAGATGCCGTTGAAGTACGAGTTCAAGAACAAGAGCTGCGTGAAGCAGGAGCCTCTCAAGGATGTCGACGAACATCTGGCGCCCACAGCGAGTCTGGAGGATGAGGAGCTACATGAACTGCAtgcggcagctgccgctgAGGATGCGCTTTGTCCTCCTAGCACAACTACCACACTGGGTGAGGAATCCACGCTGATGGAGCCAACGAACTCGCAGCCTGCGTCCTCGACGGTCATTGTGTTGGAGCACAATCGCACGATTGTGCCGCTAAGTAAACCCTACTATGAGGCTGATCCGCCCGCATTGGCCGGCGAGCGTTATGTGCGCTTTTCGCAGCCCAGTTCGAGCATCTTGGAGACCATACTGACCAGTCAACATCGTCTGGAGgcggcagcagccgctgccaaTGCGTGTCGTCAGGCAAATGCCGCAACGCCGCCACCAACTTCACCCACTGAGATGGCCTACAGCTACAAGAAGTCGCAGCGCTATGGCAACGCCGTGAGTCCCGACTCCAGCTCGAATCTGGGACAGTCGCAGGAGCTGGCGGCGCCGCTGCCCGATCAGGAATTGTCTCTGAGACGAGAGACACTGATCAAGGGAGAATGCGCGGCTCTGATTAAGGGTGAATGCTCGCCACCGCCCCCAACgtcgcatcatcatcacaatGTCATCTATTCCCCATCCCGCTCGCACTACGAGCCCGGAGCGCATTCGCCCAACTATGCGGGCTATGCTGGCTACCCGGGAGCACAATCGTTGCATGCGGCCACCTCAACGTTCCATTCGCCCCCGCACAGCTCGCATTCGCCCTTCGACCGGCAGTCGAATGCTTCAAGCGGCGGCGGTTCGGCATCGAATCTGCATCTGCTGCAGAGCAGCACACAGATGTTGAATCATCCGTTGATGCAACCCCTGACGCCGTTGCAACGTCTGTCCCCCTTGCGCATTTCGCCACCGAGCAGCCTCAGTCCCGATGGGAATTCGTGTCCGCGCAGCGGAAGTCCGCTGAGTCCCAACTCGTTGGCATCGCGTGGCTATCGCTCGCTGCCGTATCCGCTGAAGAAGAAGGATGGCAAAATGCACTACGAGTGCAATGTGTGCTGCAAGACTTTCGGTCAGCTGAGCAATCTTAAGGTGCATCTGCGCACGCATTCCGGGGAGCGTCCGTTCAAGTGCAACGTGTGCACGAAGAGCTTTACGCAGCTGGCGCATCTGCAGAAGCATCATTTGGTGCACACGGGCGAGAAGCCGCATCAGTGCGACATCTGCAAGAAACGCTTCTCGAGCACCTCGAATCTGAAGACACATCTTCGACTGCACAGCGGCCAAAAGCCTTACGCCTGCGACTTGTGTCCGCAGAAGTTCACGCAATTCGTGCACCTGAAGCTGCACAAGCGATTGCATACGAATGATCGGCCTTATGTGTGCCAGGGCTGCGACAAGAAGTACATCAGTGCGTCAGGGTTGCGCACACACTGGAAGACCACCAGCTGCAAGCCGAACAATCTGGAGGAGGAGCTGGCCATGGCCGCAGCAGCGACTTCCGAGTGTCTAGACAAAGACTTGCCGGAGCCGGACTCTCGTGAGGCTTAcgaacagctgcagcagcacatGCATCCAGGACATGCGGTGCACCCGAGTCTGCGGCATTTGACGGGCGGTCAATCACCGCCTCGTCTTATACCGCTCGGCAGCAACGCGCAGCCGCCGCATTTGCATATGCCACAtcctcagcagcaacagcagcagcagcaacagtcgcaacagcagcagcaaccatcaGCTGGCCACTTGTTGCAGCCACCGCCCATGCTGCTGACCACAGCGCCCAATGCGCCACATcatctgcaacaacagcagcagcagccaacggagcatcagcagctgcagcatttgGGCCCAGCCGCGCATCATTTGTCCCCCAAATCGCTGAAGCAGGAGGCTGGCTATCTGCATGGCCACGGACACGGCCACGGACATGGTCACAGTCATGGTCATACTCATGGACTGGGACATGGACATGGTCATGTGCAGGCGCAGGAGAATCGACCCTCGGTCATTGAGTCCTCCAATCAGCCCATGATCATTAAGTGCACGTAG
Protein Sequence: MHGLHQHPQQPQSASQSTSAQPTPASMKTASNVQQQQQQQQQQQQQQHIAIQHPHAHAHAHALANHHPHHPHHPHHPQHHAHPQHAAKLLRRSRSRSRSRSPTPDGSQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLQVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVEDEDEDDELPHKKPHYAMPAAPEIPAEVAVSHITYVMGLHLPGAAPAPASSTAAAPTSAASTQCCRRGSPPAHVSTTTTTPATTQSAHPHIQHSRHASVIIGQDRSPLNSCSDKDNVNSAVSEHHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVTPPAPSTPPHAATPSSCQPEADKNEYRKFKVKMPLKYEFKNKSCVKQEPLKDVDEHLAPTASLEDEELHELHAAAAAEDALCPPSTTTTLGEESTLMEPTNSQPASSTVIVLEHNRTIVPLSKPYYEADPPALAGERYVRFSQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQSQELAAPLPDQELSLRRETLIKGECAALIKGECSPPPPTSHHHHNVIYSPSRSHYEPGAHSPNYAGYAGYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLQQHMHPGHAVHPSLRHLTGGQSPPRLIPLGSNAQPPHLHMPHPQQQQQQQQQSQQQQQPSAGHLLQPPPMLLTTAPNAPHHLQQQQQQPTEHQQLQHLGPAAHHLSPKSLKQEAGYLHGHGHGHGHGHSHGHTHGLGHGHGHVQAQENRPSVIESSNQPMIIKCT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00553931;
90% Identity: iTF_00553931;
80% Identity: -