Basic Information

Insect: Drosophila niveifrons
Gene Symbol: BCL11A
Assembly: GCA_035046325.1
Location: JAWNOC010000063.1:10382286-10398459[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.027 1.7 9.2 2.4 1 23 292 315 292 315 0.95

2 6 2.6e-06 0.00017 21.8 1.0 1 23 784 806 784 806 0.97

3 6 0.012 0.8 10.2 4.7 1 23 812 834 812 834 0.99

4 6 1.2e-06 7.5e-05 22.9 3.2 2 23 1124 1145 1123 1145 0.97

5 6 1.5e-05 0.00098 19.4 3.3 1 23 1151 1173 1151 1173 0.99

6 6 2.8e-05 0.0018 18.6 0.4 1 22 1181 1202 1181 1202 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.027	1.7	9.2	2.4	1	23	292	315	292	315	0.95
2	6	2.6e-06	0.00017	21.8	1.0	1	23	784	806	784	806	0.97
3	6	0.012	0.8	10.2	4.7	1	23	812	834	812	834	0.99
4	6	1.2e-06	7.5e-05	22.9	3.2	2	23	1124	1145	1123	1145	0.97
5	6	1.5e-05	0.00098	19.4	3.3	1	23	1151	1173	1151	1173	0.99
6	6	2.8e-05	0.0018	18.6	0.4	1	22	1181	1202	1181	1202	0.97

Sequence Information

Coding Sequence: atgtacaacaaaatGCTGTCAATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCCACAGAGAACGATGCTGTCGCCGCACAGGACATCCTGACGTGCGGTGCCTGCCAGAAGACCTTCGCACTGTCGGACATCGTCCGATTCATACAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCCAGACAACACAAGCGCCTAGCATGGATCGCGATGCTGATGAGGGACGTCCGCTGAGTCTCGTCAATCGTCGTCCTTCTATATCGGCGCCCATCACAAATGCCGCACGCAAATCGGCGCCCGTTGGCAGCGCCACAGCGCCAGCAAGTGGACAGtccgcagcagccgcagcagcagcggtggccacagcagcagccgcagcagctgcagcggcggcagcagccacagcggcAGCGAGCGGTTCACGCATCCACACACCGCCACCAAGTCCGGCGGATCTGTTGGCCGATGGCGCCAGCAGCACACCCAAACGCCTCGTAGACGAGAATGACAATACAACGCCGAAGGCAGACCTCGAGCAATCGGAGCAGGCGCACATTGGTCGCAGCGACGATTGTCACTTGGATGACGatgccaacgacaacgacaacgacaatgacaatgacaatgacgtTGACAAGCCAAAGGTCAAGCAGGAGCCAACGTATGCTgacgatgaagatgatgagcaggagcaacagcacgTTGAGCTGGACActgagcaggagcaggagcaggcaACGGCAGCAGTTGATGCTGATGTCGATGCTGATTGCCAACAGCCGCTGGCGAAGCGACCCAAAATGGAGCTGGTCGATGCGGAGGCCAACACAGTGCATACAGAGCCCAGCAACTACACGTGCTCGACGTGCAAGACCCGCTACACATCGGCGTGGCGCTTGATTCAGCACGTGCAACACTCGCATGGCGTCAAGATTTACGTGGAGTCGAGCGGTGGCGCCACACTCACTGTGGCCACACCAGCCGCACTCAATGCCGCAGCCTCGGCTGCTGCgaatgccagcaacaacaacaacaacagtggcagcagcaaccacagcagcccCAATCGCAGTCTCagtccaacagcagcagcggctgccgcagccgccgcagcagcagcagccgcagcagctgtgggcgtgccgctgccgttgcatGCGCTGATGGCGCAGGCAGTTGCCTCGCAGTCCGTCTCGCCGGCGGccaagcgcagcagcagcaatcacaacaacagtagcagcagcagcagcaacaacagcagcagcaaccacaacaacagcagcaatcacaacaacacagcagcaattgcagcgaacacaagcagcggcagcagcagcaatgccaGCGTCAGCAGCCACTCTCCCAcacagcaactgctgcagcagcaacagcgtgcacaacagcaacaccagcagcagcagcaacaacagcaacagcagcagcagcaccaacaacaacagcagcagcagcagcaacagagcatGGCCACGGCAATGGCGGCAGGTATGCGGCATCATCCGCTGCTGGCGCCGCCAGAGGCGATGCACCCGAATCCGTTCCAGCTGCTGCGCATGCCGCTGCCCCCAGCGCTGGCCCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTCTTCGGTCGTCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTGAGCGAACAGTTTCGCCATCATGGCTTCAATCtggctgccgccgccgccgctgcccaGGCGCAGTTCAATGCcgccagcaaccagcagcagcagcagcaaccaactcCTGGTGTTGCCGTCAATGTTCCTAATCCCGTCGAGCAACGGCCGCCgtcaagcaacagcagccagcgtGGCTCAGTGCCGCCTGCCTCGTTGCCGCCCCCATCGCTCAgctcgcagcagcagcagcaacaactgcagcagcagcagcagcagcaacagcagcaaacacaaccccagcaacagcagccacaacaatcCGCAGTGAGTCCGGCCAGCCTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGTGGCGCCCGTTACACCGCGTCCTCACTCCCTGACGCCACCCGAGAAGCCGGAGAATGGCAACGCCAACAACTTGACCCTACCCAGCACTCCGCGTTCGGCCAGCACGCCACCGCATAGCAAGCCACAAGCAGCGGGAgcggcagcaaccacagccGGGGATGAGATGGAGGCGAATTGCTTTGCCTGCGGCTACTGCGACAAGAAATTCCGGTTCGAGAACAATCTGATCATACATCAGCGCACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAATGCTCGCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGTCCCACCGCCGAGGGACAcgacggcggcagcagcaatggtGGCGATAACAATCAGGACGGTCACGATGGCGGCAGCAATGCGGACTCGCTCGAAACGAACGAGGCTGACAACGACGATGATCCCAATCCCGATGAGACCGACGAGGAGTTGAACGACGAGGACGTCGATGGTGATGCCGAGGGTGAGGGCGAAGATGAGGACGAGGATGAGCTCGAGGATTGCGATGATGTTGACTACGAAGCCGAAGATCTGAGCGTGAACAATCGCATCGATGGCAAGAGCCAGAGTCCCAAGACCACCAGCTCCGGTGCCACCTCGCTGGTCGGTGAGCTGATGGACAAGTTCGGACTTTCGAACATCGCCCAATACTCCGAAGCGTACAAGCAGGCGCTGCAGGAGTCGGGACGCAAAGAGGCCGCCGCTGTcgcagctgccgcagccgctgcagcCGCCGCTGCTGGCGTGGACAACAATAATCGCGGTGGCTCAGGAGGTGCGGGCGCAGCTGGTGGAGGCTCCGCCGGAGGCAACGGCGCTCAGCCGCTGTCGGACAAACTGAACGGTTTGCCGGTTGCGGCGTTGAGACTGCGCGACGAGTTCGCCAAGAACTGCAACATGTTCCAGCCACAGCCGCAAGATGCACCCACAGCCGCCCAGGTGCCGCTCTTCAATCCCTTCCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAGATGGACGGCGGCGACTGGTGGGGCATGTCGGCCCTCCACCGCAACGAGGCGCTCTTCGAGAACTTGAAACTGAAACCCTTGGGCCTGGGCGGCGCCAACTCGCTGCTCCAGGGACCGCTGCTGAAGAAGGAGAGCCGCCAGCGGAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACGGTGCATCGTCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGTCGCACCGGCAAGGACGTCTACCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCTACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAAAGCAGCCGCCGCTGCGGCGAATGCGGCCAacgctgtggctgctgcccaagctgccgctgccgctcaACAGTTGCAGGCAGCGGCCcaggctcagcagcagcagcagcaacagttgccgaCGCCGTCGCAGCTGTCGCCCGCCTGTCCCATGGGCGTGGCAGTCGGTTTCCCGCCCCAGTTCGGTACGATGGGCGGACACAATCTGTCGCTGCCGGGTAGCGTGAGTGGGGACAACGATTCGAACGCCTCGTCCAGCCTGCCAGCGCACTCGATCTCCCTCAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCQTTQAPSMDRDADEGRPLSLVNRRPSISAPITNAARKSAPVGSATAPASGQSAAAAAAAVATAAAAAAAAAAAATAAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADLEQSEQAHIGRSDDCHLDDDANDNDNDNDNDNDVDKPKVKQEPTYADDEDDEQEQQHVELDTEQEQEQATAAVDADVDADCQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESSGGATLTVATPAALNAAASAAANASNNNNNSGSSNHSSPNRSLSPTAAAAAAAAAAAAAAAAVGVPLPLHALMAQAVASQSVSPAAKRSSSNHNNSSSSSSNNSSSNHNNSSNHNNTAAIAANTSSGSSSNASVSSHSPTQQLLQQQQRAQQQHQQQQQQQQQQQQHQQQQQQQQQQSMATAMAAGMRHHPLLAPPEAMHPNPFQLLRMPLPPALAQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNAASNQQQQQQPTPGVAVNVPNPVEQRPPSSNSSQRGSVPPASLPPPSLSSQQQQQQLQQQQQQQQQQTQPQQQQPQQSAVSPASLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSVAPVTPRPHSLTPPEKPENGNANNLTLPSTPRSASTPPHSKPQAAGAAATTAGDEMEANCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPTAEGHDGGSSNGGDNNQDGHDGGSNADSLETNEADNDDDPNPDETDEELNDEDVDGDAEGEGEDEDEDELEDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAAAGVDNNNRGGSGGAGAAGGGSAGGNGAQPLSDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPTAAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQLPTPSQLSPACPMGVAVGFPPQFGTMGGHNLSLPGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: iTF_00472584;
80% Identity: -