Basic Information

Insect: Drosophila niveifrons
Gene Symbol: -
Assembly: GCA_035046325.1
Location: JAWNOC010000041.1:482055-486827[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0011 0.069 13.6 2.4 1 23 137 159 137 159 0.98

2 15 6 3.9e+02 1.8 3.5 1 23 165 188 165 188 0.95

3 15 8.4e-05 0.0055 17.0 1.1 1 23 386 408 386 408 0.98

4 15 1 65 4.2 2.3 1 23 414 437 414 437 0.92

5 15 0.31 20 5.8 1.4 1 23 463 486 463 486 0.92

6 15 0.0012 0.078 13.4 1.9 3 23 756 776 755 776 0.92

7 15 0.048 3.1 8.4 1.4 1 23 782 805 782 805 0.98

8 15 1.5 1e+02 3.6 1.1 2 23 842 863 841 864 0.90

9 15 0.0043 0.28 11.7 0.8 1 23 885 908 885 908 0.97

10 15 0.033 2.2 8.9 0.6 1 23 1148 1171 1148 1171 0.90

11 15 0.00053 0.035 14.5 4.2 1 23 1184 1206 1184 1206 0.98

12 15 0.00084 0.055 13.9 0.1 2 23 1212 1234 1211 1234 0.89

13 15 0.0027 0.18 12.3 3.0 2 23 1241 1265 1240 1265 0.90

14 15 0.094 6.1 7.4 0.1 1 23 1270 1292 1270 1292 0.96

15 15 0.0027 0.17 12.3 0.6 1 23 1298 1321 1298 1321 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0011	0.069	13.6	2.4	1	23	137	159	137	159	0.98
2	15	6	3.9e+02	1.8	3.5	1	23	165	188	165	188	0.95
3	15	8.4e-05	0.0055	17.0	1.1	1	23	386	408	386	408	0.98
4	15	1	65	4.2	2.3	1	23	414	437	414	437	0.92
5	15	0.31	20	5.8	1.4	1	23	463	486	463	486	0.92
6	15	0.0012	0.078	13.4	1.9	3	23	756	776	755	776	0.92
7	15	0.048	3.1	8.4	1.4	1	23	782	805	782	805	0.98
8	15	1.5	1e+02	3.6	1.1	2	23	842	863	841	864	0.90
9	15	0.0043	0.28	11.7	0.8	1	23	885	908	885	908	0.97
10	15	0.033	2.2	8.9	0.6	1	23	1148	1171	1148	1171	0.90
11	15	0.00053	0.035	14.5	4.2	1	23	1184	1206	1184	1206	0.98
12	15	0.00084	0.055	13.9	0.1	2	23	1212	1234	1211	1234	0.89
13	15	0.0027	0.18	12.3	3.0	2	23	1241	1265	1240	1265	0.90
14	15	0.094	6.1	7.4	0.1	1	23	1270	1292	1270	1292	0.96
15	15	0.0027	0.17	12.3	0.6	1	23	1298	1321	1298	1321	0.96

Sequence Information

Coding Sequence: ATGGCGAGCAAGCGATTGAAAATAGATGACATGCCTGTGGATTATAAATTTGCCTGTCGCTGTTGCCTAAAATCCGAGGCGGAGTTCTTCAAGCTGGACGCTCTAACCGAGGCTGGTTTAATAGACGACAACAATGGGCACTCCATAAAAATACCTCTAATACGCTTGCTATTATTCTGCATGCGTACCGAAAATCTGCCTGAGCTGCCGCAATATATTTGTGCTGATTGTAGTAAGAGCTTGCAAATTGCTTACTTTTTCATACAAAACGCTCAAAAGGCTCATGAAATTCTCTGTCGCAAATTGTGCCCTGGCAAGATAACGAAGGCGACAACGCGATTCAATGGTCAACCACCCCTAGAGCTGTATAGCGGGGATAATGTGAAGCCCTCAAAGTCTTCTGTTCGCCACGAATGCAAAATCTGTGGCACCATTACTAGTAGTCATCTGGAACTCAAGCAACATGTTCGCATGCATTCTGAGCAAACGCGTCATTCATGCAAGTTGTGCAAATTCGTGACGTTTAAGCAGCGACAGCTTCCTGAGCATTATAGGAAAGCGCATGGCTTAACGGTTGCTCAAATAGATCAGCAGTTGAAAATGCGCAAATCCTTGCAGGCGGCTATGTCCTCAACAAATGCGACATCATCAAGACAAGCGAGGGCAAATGATGATGCACAGGTGAAGGTGTGTACCCTGGAGGATATGGAGTTGCTGATTCCCACTGTACTGACTCCTGAAGACTTCTCGCAGCCTCAACTGGACGCGGATCAACTACGTGATATTGAACAACAGCTGGGGAACTCAATAGATGGGAGTAATTCCGCCGTCTTGCCGAATGATGATCCGACGGGTGGTATCTCGAATATGAGTATTGGGGCGGAGTTTCTTGTCATGCCCGATGGGTCGTTGCAGCAAGTGCACGGTGGTGCTGGGGTTGTCTTTGAGTACATCGATGACAGCAAAACCCCACAGCAAATAACGACAAATGTCACGACAAACGTAAGTCTGCAGAACTTACTGGATGACTCCAAGCCGGATGTAACGTACAGTGCAAAGGATATTGAAATGAACTTTCCCATCGGAGATTCATTGCCACAAATCACTGTGAAACCAAAACTTCGACCAGGTCCAGGATCGACGAGTTTAATGAAGCATAAGTGTAATCTGTGTCCCAAAGTATTTCCCACAATTGCACGCCTTAAATCTCATCAATTAACTCATAGTCATTTACCCAAGTTTTATTGCGATCAGTGCTCTTATCACTCGTTGCGCAGCTCCGATCTCATCAAGCACTATACAGAGGAGCATAAGTCTTCCATTGGCGATAGTAAAATTCACGTCGAGAAATCCTTGCAGTCGCGGTCAATGGACAAAAGTCGGATCTACTCCTGCGACATGTGTTTGTTTGAGACACCAAGTAGTGCCCATCTAAGATCGCACTATAGTGATAAGCACATGATACAGCCAAGTGACATCCAACTGCGTCCCAGTTGGTCTAACGACACCAAGGATAAGGGATGCAGCTCATCGCATTTGCCTCTTGGTATTACATATCCATCAACAATCACTGAatcatcgacaacaacagagtCGACTACAACGGTACAGGAGCTACAACCTGCTCAGCCGACAACTTCAGCTGCGGTTATGCCTGGTGGCGATATAAACGTTGTTGTGGATGCCAGCTCGTTATTCCATGCTGCtggagcagcaacatcaacagcgacaagtacaagtacaacaacatcaacagaaCCAACTGAGGATGTCTCTGgagcatttgaaatattccCGGAGCAATCTTTATCGAAATCCATAAGAACTACACCGAGAAAAGTCGATTTAAGTGGCATTCTGCCTGCTGTCAGTGCTTCTACTACTGCTGGTGGTGGTAATAATATTGGTGTTGTTACCACAGCAAATCCAAACAATTCCATATTTGGAGACATGCAAGATTTCATTGACAACACCGACGTCGCAGCCATTTGCACTATACCAGCCGACGATATGCCTGTCGTTGATGGCGACGATATTGTGATTGATAACAATAATATGAGTTTGGATTTCGATGCAGAGAATTTGTTTGATGACTTCGAGGAGGACGTGGAGGTGGGTgaagatgaggatgaggatgatcCCGAGAATGAAGATGAGAATGAAAACAATGACGCGGCTGCCGATCAAAACTTGCTACTTAccagtgatgatgatgatgtcgatgACTTTGATGATGAGCAATCGAAGCATCTACAGAAACCATATTGTATCTATTGCAACAAAAAGTTTACCAGCCAATACAAGTTTGAGAATCATATGTTTGTACATCGCGGACTGGCGCCATATCGATGTGAACTCTGCACCAATCTGTACAATATGAAGCGTCTGCTCATACGCCACTACAAAACTGTGCACAAGCGCATGCCGACGAGGGATATGGTTCAGGCCAAGGGCGACAAAGTTACAGTGGAGCGCACAGCGATCGAGAAGCTGCACGTCGGTGTGAATAAGCCTCCCATTTTGATGTGCGCCAAGTGTCCTTTTGAATGCGAAGTGGAGGGTGAGATGCGAAAGCATCTCAATGCTCATCATGGCATTAACGACGGCGTCTCAGTGCATGCCAACGAGGTGTTTATCATACGCAAACTACCTTTTGAGTGTCCTCGGTGTATTCGCTCGTTTGCCGCAAAACGCACGTTGACTCGCCATTTGCAGCGAAGTCATTTAGTAGACACAATCATTGAGATGCAGGCGCCTCAATGGACAACCAGttcagcggcaacaacaacaaccactatGACGTCTACAACTGCCTTGCCGAAGAATGCACCATGTATTGTTGCTGAGATTGATACTGACGGCGATGgtgatggcgatgacgatggtCATGGCGATGGCAGTGGCAATGAAAAAAGCGCGATGACATTGAAAAATGATCTTTGCTCATCGCcgtgtgcaacagcagcagacaacatAGTGATAAACAGTGACACAGGAATTGAATCGGATAATGAGGATATTGACAGTAAATCGTTGACCTCAACACCAACGTCAGGATTCGcaacaactaccacaacaGCTGACACAAATGATGCTAAcgatgataaacaaaaaacaactgcaGAATCTTCGACTTTAACTTCAACCTCCCAGATAACGTCGGAATCACCGACATCACcgctaacaacaacatcaacaacaacagcgcttGAAAAAACACCGACAACATCAACACTTTTCCCAACCCCCACGCCATTTGATTTTGATCTGGATTTCATAGAAAATGGTGCGCATAGCAATCCGCTTAatagcagcaacgacaacttTAACGTTTTGCCCATCACTGGACAATTGCTAAATAGCACAGATAAACTACTAACAGCAGCATTGGAACCGTCACCAGTTAAAGATCTTCGCTCCAGGTTACCCCAAACTCCAATTTTTGTATGCAAACAATGCAATCAGACATTTGACGAATTGAGTAAAATGTTGCAGCATGAATTGGAGCAACATTCCAGCGGCATTGTATCGCCGCGTAACGTTTATCAGCATCAGTGTAAAGTCTGTAACACAACATATCGCACAGTGACGCTCTTAAATTATCACATGAAAAGGCATGCTCCTCGCAAAATTCCATGTAAGCAATGTGCCAAAGAGTTCTCAACGAGTGCTGAGCTAGAGAAACACGTGGATGCCGAGCATCGTACAAACACGGCCTTAAAATGTGGCATCGATGGCTGCGCAAAGACTTTTAATTACAAGCATCATCTTAAGCGACACCAGACAGCCTCCCATACGCGTGTGCAATACATATGTCCCGAGTGCGGACGCGATATGTTAACCAGTCTTCTTTTAAGAAACcacataaaaatgcataaggGCACACATTCCTACAAGTGTCCGAAGTGTGTTCGGACTTATATGCGATCCGGACCCTTTCAAAGACATGCGCTGCGTGAACATAAATGGGATCTTACTGAGGAtgagttaaataaaatgtatagcGTGAATGAATCCACACCTCCGATCAAAATTTGCGAACTAAGTTCGCATGATGTTGAAAACGATACTTCTGATTAA
Protein Sequence: MASKRLKIDDMPVDYKFACRCCLKSEAEFFKLDALTEAGLIDDNNGHSIKIPLIRLLLFCMRTENLPELPQYICADCSKSLQIAYFFIQNAQKAHEILCRKLCPGKITKATTRFNGQPPLELYSGDNVKPSKSSVRHECKICGTITSSHLELKQHVRMHSEQTRHSCKLCKFVTFKQRQLPEHYRKAHGLTVAQIDQQLKMRKSLQAAMSSTNATSSRQARANDDAQVKVCTLEDMELLIPTVLTPEDFSQPQLDADQLRDIEQQLGNSIDGSNSAVLPNDDPTGGISNMSIGAEFLVMPDGSLQQVHGGAGVVFEYIDDSKTPQQITTNVTTNVSLQNLLDDSKPDVTYSAKDIEMNFPIGDSLPQITVKPKLRPGPGSTSLMKHKCNLCPKVFPTIARLKSHQLTHSHLPKFYCDQCSYHSLRSSDLIKHYTEEHKSSIGDSKIHVEKSLQSRSMDKSRIYSCDMCLFETPSSAHLRSHYSDKHMIQPSDIQLRPSWSNDTKDKGCSSSHLPLGITYPSTITESSTTTESTTTVQELQPAQPTTSAAVMPGGDINVVVDASSLFHAAGAATSTATSTSTTTSTEPTEDVSGAFEIFPEQSLSKSIRTTPRKVDLSGILPAVSASTTAGGGNNIGVVTTANPNNSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFDDFEEDVEVGEDEDEDDPENEDENENNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVTVERTAIEKLHVGVNKPPILMCAKCPFECEVEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQWTTSSAATTTTTMTSTTALPKNAPCIVAEIDTDGDGDGDDDGHGDGSGNEKSAMTLKNDLCSSPCATAADNIVINSDTGIESDNEDIDSKSLTSTPTSGFATTTTTADTNDANDDKQKTTAESSTLTSTSQITSESPTSPLTTTSTTTALEKTPTTSTLFPTPTPFDFDLDFIENGAHSNPLNSSNDNFNVLPITGQLLNSTDKLLTAALEPSPVKDLRSRLPQTPIFVCKQCNQTFDELSKMLQHELEQHSSGIVSPRNVYQHQCKVCNTTYRTVTLLNYHMKRHAPRKIPCKQCAKEFSTSAELEKHVDAEHRTNTALKCGIDGCAKTFNYKHHLKRHQTASHTRVQYICPECGRDMLTSLLLRNHIKMHKGTHSYKCPKCVRTYMRSGPFQRHALREHKWDLTEDELNKMYSVNESTPPIKICELSSHDVENDTSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00553910;
90% Identity: iTF_00553910;
80% Identity: -