Dniv001966.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila niveifrons
Gene Symbol
RREB1
Assembly
GCA_035046325.1
Location
JAWNOC010000020.1:4895408-4902977[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.035 2.3 8.8 0.8 1 21 259 279 259 281 0.93
2 13 0.00033 0.021 15.2 0.2 1 23 291 313 291 313 0.98
3 13 8e-05 0.0052 17.1 7.3 1 23 319 341 319 341 0.98
4 13 0.2 13 6.4 2.5 2 20 566 584 566 586 0.93
5 13 0.0083 0.54 10.8 0.1 1 23 742 764 742 764 0.97
6 13 1.2e-05 0.00079 19.7 0.7 1 23 774 796 774 796 0.99
7 13 0.00082 0.053 13.9 2.0 1 23 802 825 802 825 0.97
8 13 0.0029 0.19 12.2 2.0 1 23 1080 1103 1080 1103 0.95
9 13 8.5e-05 0.0055 17.0 0.3 2 23 1458 1479 1457 1479 0.97
10 13 0.14 9.3 6.9 6.3 1 23 1485 1508 1485 1508 0.97
11 13 1.9 1.2e+02 3.3 3.8 1 23 1642 1665 1642 1665 0.85
12 13 0.0083 0.54 10.8 0.5 3 23 1728 1748 1726 1748 0.96
13 13 0.0014 0.089 13.2 4.8 1 23 1754 1776 1754 1776 0.99

Sequence Information

Coding Sequence
atGCTGGCCacacaaccacagcaacaacaacaaaacacagcgacagcagcaacagttgctgccgcagcagcagcagcagcgacaacaacaacaacagttgcccaCAGCGATGATGCGCATAGCTTTGatggagagcgagagcgagagcgacgCGATTCGACGACATCAGAATCATCGCTGGAGCATCTCGATTTGGGACGCACACCAAAGaaactgagcagcagcagcggagcGCCGCAGCCGACGTCGACGCCACACGAGacatcgacgtcgacgtcagcgGCGACGTCATCACGCAAACGCAAActgcgacaacagcaacaacagctacaacaacaaatgtccgatgaagaacaagagcaaaaacaacagcaacaaatgcagcTGGAGACAACAGCGtcgcagcgactgcgacacaAGCAGCGACGCAACGTCACAGCGAGCGCTAGCATCGTTGTCGATTACAGCGCCAGCGGCGACGCGAGTTCGCTGCGCAAAAAGTTTCGTCtcaatcgcagcagcagcagcagcggcaacgcaGCCGCCAATGGCGATCTCTCCGAATCGGGCTTCGTCGATGgcagcagcgccaacagcGGCTATTTGCTCAGCAgtagcagcggcagcgcagTCGCCGCCGCAGTCGccgtagcagcagcagcgcagcaacagcagcagatgtCATCGAGCAGCTCAGGCGGATCATCGCCACAAGGCGGTTTGAGTTTGTCGAGCGCCGAGTCGGGAATTGGCGCTGGCGATGAGCACATGAAATACTTGTGCCCCATCTGCGAAGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAATTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCGAAGGTGCTGTCGTCGGCCTCATCGCTGGATCGTCACGTGCTTGTGCACACTGGGGAGCGACCCTTCAACTGCCGCTATTGCCACCTGACATTCACAACGAACGGCAACATGCATCGTCAcatgcgcacacacaaacagcatcagcaacagtcacagcagcaatcacaacagcagcagcaacagtcacagcagcagcagcaacagtcatccgcacagcagcaacagttgcagtcacagcagcagcaacagcgacgtcatcaacagcaacatgcgACAACAGCTGCAAGTGGAGCGCAGCTGACAGCGGGGCGAGCGGAGAGCTATGAAAGCGATGCCAGCTGCTCGACGGATGTCTCGAGTGCAGCgagtcacagcagcagcagcagcaaccacagcagcagccaacgttccctccacaacaacaacaataacaacaacagcaagttgagtaacaacaacaacgagctaAACTTGGAGCTGGAGAACAAACAGCGACGCCACAAActcatcagcaacaacaacaacaacgaagaagCTTCGGAGCAACCACAGCTGAAATCCGAAGCAGAGGAcaatgatgaagatgatgatgtggGCAGCGAatcggaggaggaggaggaagtaACACAAGTGATCACAAGCACACCCGATGTGGCCACACTGCTGGCGAGCTCCTCCCGCTCGGGGGGCACAACACCGACGCAGTTGCTCTCGCTCAGTTGTCCGGCGTGTGCGGCAGATGAGTTTGAATCGTTGCCGGCGCTGTGCCAGCATCTGGATGCCCAGCATGCGGATATACCGGCGAAGTGTCGCGAATGCGATGTCATCTTTGCCAGCCATCGTCAGCTGCAGACGCACAGCTGTCGCATGcaactgttgccgctgctcgGCGCCAGCTCATCCCCGTTGCACAAGCACGAACATGACGATGAGGAGAACAATGATGTTGCTCACGATGTtgatggcgatgatgatgatgtggcgGAGGAGGCTAgagcgcaacaacagcacagcgAACGCGATGATTTCTTTCAGCAACTGTATCTCAAGGGTAAATCCTCAGCGTTggcacaacaccaacaacctTCTTTGCCCTCTCCGATCAAACACGAACCCTCGACGAATGCAAACGATAGCCGACAGGATTTGGCCGACATTCAGAGCATACTGAACATGACCAGCTCCAGTTGCACCTCGAGTTTTCTGCGCAACTTTGAGCAATCGGTGAACACGCCCTGCTCCAGTCAATACAGCCTCGACGGTCGCGATGGCGATGAGGAGGCACAGGATGCATTCACCAGCGAATTTCGACGCATGAAACTGCGCGGTGAATTCCCCTGCAAACTCTGCACCGCCGTCTTTCCCAATCTGCGTGCCCTCAAGGGTCACAATCGTGTCCATCTCGCTGCCGTCGGTCCCGCGGGTCCCTTCCGCTGCAACATGTGTCCCTATGCCGTGTGCGACAAGGCCGCCCTAGTGCGTCACATGCGCACCCACAACGGGGATCGTCCCTACGAATGCGCTGTGTGCAACTATGCGTTCACCACGAAGGCGAACTGTGAGCGCCATTTGCGCAATCGTCATGGCAAAACGAGTCGCGAGGAGGTCAAGCGTGCCATACTCTATCATCCCGCCGAGGATGCCAGCTGCGAGGATGCGAAGTCATCCTCGGGTCAACAGGAGCTCGCCGAGCTCAGCTATCGCTCGGcaacgccgccgccgtcgtcggAGTCGACGAGCTCACAGCTCAAGCACATGTTGCTCGCGGCCGAGGCGCCGAAGATACAGGTGAAGAGTCTCGATCAGTTGGTGGAGAAGCCAGCGGCAGCCATGGATCTCAACATGGATGTGCTCGATCTGAGCAAGAAGCCAACGTTGTTGGCTCAGGAGTTGCTCGAGCAGCGCGAACGtgagcgggagcgggagcgtGAACGGGAGCGGGAGCGTGAACGGGAGCGTGAACGCGAACAcgaattgctgctgcaacagcagcaacagcaacaacaacagcagcaacaacaactttttggcGCTGGCGAGGCGGCCACACAGTATATGCAGCAATTGTTTAGGAATCTCATGTTCCAGCAATCGCCGGGATTTCCCTTCTTCGGTTTCATGGCGCCACCGAACacggcagccacaacagcagcagccacaactgACAAATCTaacgccacagcagcagcagcaacagcagcagccgctgctaCGCCTCTTGGACTGCCACTGCCCCTGCCGAATGTGGGCGTACCGGTGCCAGCGGGCGGACCCGTCAAGATGGTCATCAAGAACGGTGTGCTAATgccgaagcagaagcagcgtcGCTATCGCACCGAACGTCCCTTTGCCTGCGAACATTGCTCGGCACGTTTCACGCTCCGCTCCAACATGGAGCGTCATGTGAAGCAACAGCATCCGCAGTTCTACGCCCAACGTCAGCGCAGCGGACATCATGTGATGCGCGGACGTGCCGCATCCTCAAgtgccgcagccgcagcagcagcagcagcggcagcagcagcagccgccgcagcagcagccatgaACAACCtaagtcaacagcagcaacaacaacattcgcATCATGCGCATCATCCGCACATCTCGGATCAGGTGAAGTACGCGATACTCGCACAACAGCTGAAGGCGCGCAAGGATACGGATCTGTTGCAGCAGGCGCTGGCACATGGCTCGAGCAGTGTTGTGGCTGGCAACGCCACAAACAATGCGCTCTTGCACTTTGGCTACAAAGCTgccaacagcaatggcaatggcaatggccagAGCAACGGACATCATGCGGCGACGctcaacgatgacgatgagccACCGAAGTTGATTATCGACGaagacgatgaggatgagttCGATGAGGTAGAGGATgaggacgatgacgacgacgtcgaggAGGAGTTAGATGAGCAGGagcaacagtcacagccacCGCAGCAACAGCCGGAGGATCAGGCTGAGCCCGAACTCATCGAGGAGTCCACCCCACGCAGCTCTACGCCCATTGTGGCCGCCAAAAAGGTTGCGGAGACCATACTCGAGCAGGCCATCAAGGCGGGCAGCAAATCCGATGCAGCGACGCTCTCCAAGACTCCTCCGCCAGTCACACCCACACCCTCAACACCTCCCGCACCGCATTCGATGAAAACCCTAATCGCTCAAGCCGAGTCCGTGGCGAAATCGTTGAAGGAAGTGGCCAGCTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGTCGAAGCTGGTGGACAACGCCACCAGCAATCAGGTGTCGTTCAATAGCTATTTTCGCCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTTTAGTTGCCTCGGGCAGTGCCAGCGAGAGCAACAACTCCGGCACCGAAGATgtgaccagcagcagcagcagcggcaacgaaCCGAAAAAGAAATCCGCCTACAGCTTGGCCCCGAATCGCGTCAGTTGTCCCTACTGTCAGCGCATGTTCCCCTGGAGCAGCTCGCTCCGGCgccacatactcacacacaccggCCAAAAGCCGTTCAAGTGCTCCCATTGTCCGCTGCTCTTCACCACCAAGAGCAACTGTGATCGCCATCTGTTGCGCAAGCACGGCAACGTCGAGTCCGCGATGAGCGTTTATGTGCCCACCGAGGACGTTAGCGAACCGATACCGGTGCCCAAGTCCGTTGAGGAGATCGAACTGGAGGAGCAGCGACGTCGCAAGGCCGCCGAAGCCGAGTTGGAACGCGAACGGGAATTGGAACGTGAGcgggaacgggaacgggagCGGGAACGCGAAAGGGAGCGTGAACAGGAACTGGAGCGTGAACGGGAGCGGGAGCGACGTCAGTTGGAGCAGGAGCGcgaacaacagcagctcatTCAACAGCTGGTCAGTCAGCAAATggccgcagcggcagcagcagccgcagcagccgctCTCAATGGGGAGACTGCAAGCTCAGCGGGAGCTCCGGGCGCAGGCGAGGCACAAGGCAGCGATTTGCCCTACAAGTGTCATCTGTGCGAATATTCATTTGCGGAGCGTTTGCAGTGCTTGGATCACAtcaagcagcagcatgcaCAGGAATTTGCACTGCTGCTCGCCAAGGGCGCCATCGAAACGGAAAGTGGAGatctgcaacagcaacagcagctgcctcctcctcctcctcccgcCCCTGCGCCCGCTTCCGATGAGGAAAACAGCGCCACAAATCCGTCGTCACGCAACAAATATCCCGACTACAGCAATCGCAAAGTGATCTGCGCCTTTTGCGTTCGTCGCTTCTGGTCCACCGAAGATCTGCGTCGCCATATGCGAACCCACTCGGGGGAACGTCCGTTCCAATGCGACATTTGCTTGCGCAAATTCACGCTGAAGCACAGCATGTTGCGGCACATGAAGAAGCACAGCGGACGCAGTCACAACGGCGAGCAGGGACAATCCGATTGCTCCGATGATGAGCAGAGCGCTCTCAACAGTCCGCCCAGCACTCCTAAtcccacacacaacaacaacaacaacaacaatactagcaacaacaataacaacaacaacacttgccacaacaacaataacaaacagagCTTGCGTCTGCCCAAGTTGCATGAGCTCCTTGATAAGGCAAACGAGTGGCGCGAAAGTCATCTCGGTGAGCACAAGGAGAACATTGGCGAGGCCAGCAAAccttcgtcgtcgtctgtgGCCAGCGGTGATCTGATTGGCAATCTGCTCGGCATCAGCGATCAGGGCATACTCAACAAGCTGCTCTCCTCCGCCGATGAGGCAGCCAAGCTTCTCGGTGTGGACAAGTAA
Protein Sequence
MLATQPQQQQQNTATAATVAAAAAAAATTTTTVAHSDDAHSFDGERERERRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHETSTSTSAATSSRKRKLRQQQQQLQQQMSDEEQEQKQQQQMQLETTASQRLRHKQRRNVTASASIVVDYSASGDASSLRKKFRLNRSSSSSGNAAANGDLSESGFVDGSSANSGYLLSSSSGSAVAAAVAVAAAAQQQQQMSSSSSGGSSPQGGLSLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQSQQQSQQQQQQSQQQQQQSSAQQQQLQSQQQQQRRHQQQHATTAASGAQLTAGRAESYESDASCSTDVSSAASHSSSSSNHSSSQRSLHNNNNNNNSKLSNNNNELNLELENKQRRHKLISNNNNNEEASEQPQLKSEAEDNDEDDDVGSESEEEEEVTQVITSTPDVATLLASSSRSGGTTPTQLLSLSCPACAADEFESLPALCQHLDAQHADIPAKCRECDVIFASHRQLQTHSCRMQLLPLLGASSSPLHKHEHDDEENNDVAHDVDGDDDDVAEEARAQQQHSERDDFFQQLYLKGKSSALAQHQQPSLPSPIKHEPSTNANDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAILYHPAEDASCEDAKSSSGQQELAELSYRSATPPPSSESTSSQLKHMLLAAEAPKIQVKSLDQLVEKPAAAMDLNMDVLDLSKKPTLLAQELLEQREREREREREREREREREREREHELLLQQQQQQQQQQQQQLFGAGEAATQYMQQLFRNLMFQQSPGFPFFGFMAPPNTAATTAAATTDKSNATAAAATAAAAATPLGLPLPLPNVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSSAAAAAAAAAAAAAAAAAAAMNNLSQQQQQQHSHHAHHPHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVVAGNATNNALLHFGYKAANSNGNGNGQSNGHHAATLNDDDEPPKLIIDEDDEDEFDEVEDEDDDDDVEEELDEQEQQSQPPQQQPEDQAEPELIEESTPRSSTPIVAAKKVAETILEQAIKAGSKSDAATLSKTPPPVTPTPSTPPAPHSMKTLIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEAELERERELEREREREREREREREREQELERERERERRQLEQEREQQQLIQQLVSQQMAAAAAAAAAAALNGETASSAGAPGAGEAQGSDLPYKCHLCEYSFAERLQCLDHIKQQHAQEFALLLAKGAIETESGDLQQQQQLPPPPPPAPAPASDEENSATNPSSRNKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRSHNGEQGQSDCSDDEQSALNSPPSTPNPTHNNNNNNNTSNNNNNNNTCHNNNNKQSLRLPKLHELLDKANEWRESHLGEHKENIGEASKPSSSSVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00553919;
90% Identity
-
80% Identity
-