Basic Information

Insect: Drosophila niveifrons
Gene Symbol: -
Assembly: GCA_035046325.1
Location: JAWNOC010000052.1:34372827-34377051[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.27 18 6.0 5.3 2 23 358 380 357 380 0.96

2 18 0.13 8.6 7.0 0.1 1 23 387 412 387 412 0.94

3 18 0.024 1.6 9.3 1.8 2 23 423 444 423 444 0.93

4 18 5.6 3.7e+02 1.9 3.0 2 17 455 470 454 481 0.75

5 18 0.1 6.7 7.3 0.5 3 23 514 534 512 534 0.88

6 18 0.00037 0.024 15.0 0.2 1 23 542 565 542 565 0.98

7 18 8.9e-05 0.0058 17.0 0.3 2 23 570 591 569 591 0.97

8 18 0.61 39 4.9 0.1 1 20 599 618 599 620 0.93

9 18 0.00015 0.01 16.2 0.6 1 22 639 660 639 663 0.90

10 18 0.0032 0.21 12.1 1.3 1 22 668 689 668 689 0.95

11 18 0.19 12 6.5 0.5 1 23 708 733 708 733 0.95

12 18 0.057 3.7 8.1 2.0 2 23 749 771 748 771 0.93

13 18 0.078 5.1 7.7 0.7 3 23 778 799 777 799 0.93

14 18 0.0026 0.17 12.4 0.5 2 23 803 825 802 825 0.96

15 18 9.2e-05 0.0059 16.9 2.4 1 23 831 853 831 853 0.98

16 18 0.021 1.4 9.5 0.4 1 23 857 880 857 880 0.93

17 18 3e-05 0.0019 18.5 1.0 1 23 886 909 886 909 0.97

18 18 0.0006 0.039 14.3 0.6 1 23 913 941 913 941 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.27	18	6.0	5.3	2	23	358	380	357	380	0.96
2	18	0.13	8.6	7.0	0.1	1	23	387	412	387	412	0.94
3	18	0.024	1.6	9.3	1.8	2	23	423	444	423	444	0.93
4	18	5.6	3.7e+02	1.9	3.0	2	17	455	470	454	481	0.75
5	18	0.1	6.7	7.3	0.5	3	23	514	534	512	534	0.88
6	18	0.00037	0.024	15.0	0.2	1	23	542	565	542	565	0.98
7	18	8.9e-05	0.0058	17.0	0.3	2	23	570	591	569	591	0.97
8	18	0.61	39	4.9	0.1	1	20	599	618	599	620	0.93
9	18	0.00015	0.01	16.2	0.6	1	22	639	660	639	663	0.90
10	18	0.0032	0.21	12.1	1.3	1	22	668	689	668	689	0.95
11	18	0.19	12	6.5	0.5	1	23	708	733	708	733	0.95
12	18	0.057	3.7	8.1	2.0	2	23	749	771	748	771	0.93
13	18	0.078	5.1	7.7	0.7	3	23	778	799	777	799	0.93
14	18	0.0026	0.17	12.4	0.5	2	23	803	825	802	825	0.96
15	18	9.2e-05	0.0059	16.9	2.4	1	23	831	853	831	853	0.98
16	18	0.021	1.4	9.5	0.4	1	23	857	880	857	880	0.93
17	18	3e-05	0.0019	18.5	1.0	1	23	886	909	886	909	0.97
18	18	0.0006	0.039	14.3	0.6	1	23	913	941	913	941	0.87

Sequence Information

Coding Sequence: atgtCGAAAGAAAATTCCGAAAGCAGCCCTAGCTGCCTGCATTGCAGAGTGCACGATTCAAAACAGACATTTCATGAGATCTTCGACGATGTGGGCATTGATATCGAATTGCCAAATTTACTGGCCaagtattttcaattgagTGTCAAACCCGATCCAAAAAAACAGCAGTTGTTGTGCCTAGAGTGTGTGAATACGCTAATTCGATTCTTCGACATCGACGAACTGCAAAGAGAACAGGATGCGGCAAACGCTGCCAAGAAGGATAAGACAGTCGGTAAAAATGAAGCCAAGACCGCAAGTGAGACATCAACGCCAACTCCCGCCAGGGTTGAAGCGAAGCCTGCAAAAAAACAGACGCCACCAGCGGCTAAAGCCAAAATTGAGCCCAAAAAGGAAGTCGCTAAGTTGCCGGTCAAGCCAAAGCCTGCTCCGCCTTCGGCACTGGCTCCGACTGCAGCGCCTGCAGCTGTAACTCCTCCACAGTCAGAGGAGTCCGTTGCTGTGCGCATTAGCAAAGGAAAAACATTGACTGTGACACCAAAACGTATAGAGATCAAGCCCAAATCGAAGGCCAGTCTAGAGAAACCAGTGGGCAAGCGAGGCAGCTCCAAAGAAGCTGATGCAGGGGAACAGGAGCAGATAGGCGCACTGCTACGCGACATTTTCGGAGAGGAGAAATTGGTGGCCAAAGAAAAACTCATTGAAATAGCAGAAGCAGTGCAGCGGTCGGAGAGCATCGACAACGATGAGCAGAAACAGTTGGAGGAAAAGGTACAAgaggaggagcagctgctCAAGGAACCGGACAATCCAGATGCAGACGAGCTGGAGTTTCTGCTTGAGGGTGACTCCTCGGATTTGGATGTGCCGCAATTGAAGACAGAGAAGCGCTCTTCACAAGATACAACACAATCCcaaaacgaaagcgaaagcgagaATGAAACCCACAAAGTTGAGCCCTTCAACTTTGTCTTAATCAGGGAATCCGACGACGTTGGAGATCTCTATGAATACCTTTCGACTGTGGTGAAGACCTGCTTTGAGACCTTGTCCTTTGACTGGGCCACCGTCTGTCAGCATTGCTCGCTGAAGTGCAGCAAATTTGAAACTCTGTTGAACCACATGCTGAAGTCTCATCAGCTGTCTGGGCAGCAGTTCAAGTGTCCCATTGGTGGCTGCGACAAGCAGCTGCGTGGACGCAAATTCCTGGCCATGCACTTGGTTGTAATGCACGCTCCAGTAGCTGAaATACCAATTTATGGCAGCTGTCCGGAGTGCAACCTGACTTTCTcgaatattttgcagtacAACAAACACTCTTGCGCCCATGTGATCAAAAAGCGTCGTGGCATTCGCTTGTATTGCGAAATGTGCGGCCTGGAGTTTCCCTCCTGGAAACGCTTCAACTTTCACAATCAATTCCATTTGGAGCGACATCGACCACGCGCCTGCTTTGTGTGCGATTATGCGGACAACAACATCGATGAGCTCTTTCAGCATTTGCACTACTCCCATGAACCGGAGGGTTCACTCTTTTGCGATCTCTGTGATCGCACTTTCCGTGATGCTACCATCTTTGCAGATCACAACAAATCCCATACGAATGCTACCACCAACACGTACACCTGCGGCGAGTGCAACGCTAACTTTGATACACGCGGTCGTCTCAATGGTCACATGCGCATCACGCATGGCACTGTCATCAGTTGTGAGATGTGCAATCGCGAATTTGCCACCGAAGCCAGTTACAACGTTCACATGAAGAAACATTTGATCATCGAACGCGAAGTGCATGTATGCAACAATTGTGGTTTGCTTAGCGAGAGCAATGATAAGATGACGGCTCATATCGAGAATGAGGATTCGGTTTGCTTTGGCGCCGATATCTATGTGGAACTTCTAAGAGATGCCTTCGTCTGCGAATACTGTTCCACTTACTACAAGACAAAGTCGGATTTGCGTGCTCATCGCGAATCGGGTGTGCACAAGGATGGTGTCTTCAGTTGTCAGCCGTGTGGCAAGGAGTTTAACGACATGAAATTGTATCGTCATCACATGCGCACTTATCAATTGCAGCGCGCAGATGTGGCACATCGCAAACTAGAGATTTGCCTGTACTTTATGTGTGACTATGAGgATTGCATTGAGTCGTACATCAGTTGGAATTCATTGTATACACACAAGCGACGCACTCACGATCTGGCCGAGAAGCTGGATGCCAAGCCAAAGGCCGATGAATGGATCTGTCAATTTTGCCAGAAGCAGTGTCGCTCCAAAATGTCACTCTCGGTGCATGTGGCACGCAGTCACAACAACAACAACGTTGCTTGCAAGCTGTGCAGAGCTTCTTATAAAGATGACGAGGCTTTGAAGAAGCATCATGCTTACTGGCACGAACCCGTCGAGTGTTCGTTGTGCTTCAAGGTTGTGAAGAATCGACGCAACTTTGACACACACATGAATGTGGTGCACTCGGATAACAAGCGTTATTCTTGCAGTGTTTGCCAAAAGGGTTTCTATCACAAGAGCGAAATGGAAGCGCACAAGCGActgCATAATCAATCGTATAGCTGCGAGAAATGCAGCTTCATTACAAGGAGTAAGAAATCGCTGGCTGTTCATGTGCTTGGTCAGCATTTCAGACGCTTTGCCTTCGAGTGCAAGCAGTGCACTAAACGCTTTGGCCGTCAACAGGGCTTAACCAATCACATTTTGCGAGTGCATGCCACGAAATTCACATGTCGCGATTACCTCGAAGGCGGCTGCAGCAGAGCCTTCAACACATCGGCACATCTGACGGTGCATGTGCGCAAGgtgcacaacagcagcattagTGTGAGTGACGATGTTGAGGATGAGGCCGTGGATTTGCAGCCAGAGGAGGAAGTGCAGCAGGAGGAGCAAGAGCAGCAATCAACAAGAAAATCAAAGCGACAGAGAACAACACCATCTTCTCCATTGCAAAAGAAGCGTTGCGTACGTTTGAGTAACGACACTCTGATCGAATTTATAAATGCCGAATCGAAGGAGGAGGATCAGAAAAACGCTACAGACTCGGAGATCTTCGAAGAGTTGCAGGAGAGCAAAGCCAACATCTTGCCACCGAAGCGAAGGAAAAGACAGTTGTAA
Protein Sequence: MSKENSESSPSCLHCRVHDSKQTFHEIFDDVGIDIELPNLLAKYFQLSVKPDPKKQQLLCLECVNTLIRFFDIDELQREQDAANAAKKDKTVGKNEAKTASETSTPTPARVEAKPAKKQTPPAAKAKIEPKKEVAKLPVKPKPAPPSALAPTAAPAAVTPPQSEESVAVRISKGKTLTVTPKRIEIKPKSKASLEKPVGKRGSSKEADAGEQEQIGALLRDIFGEEKLVAKEKLIEIAEAVQRSESIDNDEQKQLEEKVQEEEQLLKEPDNPDADELEFLLEGDSSDLDVPQLKTEKRSSQDTTQSQNESESENETHKVEPFNFVLIRESDDVGDLYEYLSTVVKTCFETLSFDWATVCQHCSLKCSKFETLLNHMLKSHQLSGQQFKCPIGGCDKQLRGRKFLAMHLVVMHAPVAEIPIYGSCPECNLTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCDYADNNIDELFQHLHYSHEPEGSLFCDLCDRTFRDATIFADHNKSHTNATTNTYTCGECNANFDTRGRLNGHMRITHGTVISCEMCNREFATEASYNVHMKKHLIIEREVHVCNNCGLLSESNDKMTAHIENEDSVCFGADIYVELLRDAFVCEYCSTYYKTKSDLRAHRESGVHKDGVFSCQPCGKEFNDMKLYRHHMRTYQLQRADVAHRKLEICLYFMCDYEDCIESYISWNSLYTHKRRTHDLAEKLDAKPKADEWICQFCQKQCRSKMSLSVHVARSHNNNNVACKLCRASYKDDEALKKHHAYWHEPVECSLCFKVVKNRRNFDTHMNVVHSDNKRYSCSVCQKGFYHKSEMEAHKRLHNQSYSCEKCSFITRSKKSLAVHVLGQHFRRFAFECKQCTKRFGRQQGLTNHILRVHATKFTCRDYLEGGCSRAFNTSAHLTVHVRKVHNSSISVSDDVEDEAVDLQPEEEVQQEEQEQQSTRKSKRQRTTPSSPLQKKRCVRLSNDTLIEFINAESKEEDQKNATDSEIFEELQESKANILPPKRRKRQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00553861;
90% Identity: iTF_00553861;
80% Identity: -