Basic Information

Insect: Drosophila niveifrons
Gene Symbol: -
Assembly: GCA_035046325.1
Location: JAWNOC010000062.1:7085269-7090651[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.1e-07 6.9e-06 26.2 1.8 2 23 139 160 139 160 0.97

2 9 2.9e-07 1.9e-05 24.8 1.5 1 23 166 188 166 188 0.98

3 9 1.2e-07 8e-06 25.9 1.1 1 23 194 216 194 216 0.98

4 9 7.5e-07 4.9e-05 23.5 0.7 1 23 222 246 222 247 0.95

5 9 0.00012 0.0075 16.6 3.0 1 23 252 274 252 274 0.97

6 9 0.00041 0.027 14.9 3.3 1 23 280 303 280 303 0.98

7 9 0.00018 0.012 16.0 2.7 1 23 309 331 309 331 0.99

8 9 4.2e-06 0.00027 21.1 0.8 1 23 336 358 336 358 0.98

9 9 0.0057 0.37 11.3 0.3 3 23 366 389 364 389 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.1e-07	6.9e-06	26.2	1.8	2	23	139	160	139	160	0.97
2	9	2.9e-07	1.9e-05	24.8	1.5	1	23	166	188	166	188	0.98
3	9	1.2e-07	8e-06	25.9	1.1	1	23	194	216	194	216	0.98
4	9	7.5e-07	4.9e-05	23.5	0.7	1	23	222	246	222	247	0.95
5	9	0.00012	0.0075	16.6	3.0	1	23	252	274	252	274	0.97
6	9	0.00041	0.027	14.9	3.3	1	23	280	303	280	303	0.98
7	9	0.00018	0.012	16.0	2.7	1	23	309	331	309	331	0.99
8	9	4.2e-06	0.00027	21.1	0.8	1	23	336	358	336	358	0.98
9	9	0.0057	0.37	11.3	0.3	3	23	366	389	364	389	0.94

Sequence Information

Coding Sequence: ATGGACACTATTTGTAGGCTGTGTTTTCAGACAGCGACGTTATTCCAAGTGCCCGGCTATAGCATACCAACGTGCGTGCGCTGCTCGGAACAGTTAACGAGCAATTCAAACTTCCATCAAACGGTGCGAGGAGTGCAGGATGCAGGCGCCGCTGCTTCTGTGGCGGCCGTTGCAGtagccgctgccgctgctgcctcGACGGCGGCAAATGACGCCACCGATGCGGTGGCAGCACAGTTGACAAATGgcaatgctgttgctgctgttctacaattacagcagcagcaacaacaacaacagcagcagcaacaacaacagcagcaacagcaacaattgcaatcatCGAGTTCTTCCGAGAATCTCCAATCGCAGGACGATTCAGAAGATGTGGATCTGATATTCAACGAGGAGGGCTCCTGCCCGCTGTGCAACAAGACCTTCTCGCGCAAATCCTCGCTCATGACGCACATACGAAATCATTCAGCGGAGCGCAAGTTTGTCTGCAGCTATTGCCACAAAGGCTTTACGCAGGCAGCAAATTTGCGAAACCACGAGCGCATACACACAAATGATCGACCATATCAGTGTGTCGATTGCGGCAAAACGTTTACCCAAATCACAAATTTGAACAATCACCGACGATTGCATACGGGCGAACGACCATTTGTATGTAACGAGCCGGAATGCGGACGAAGCTTTGCCCAGGTCACCAATCTGAACAATCACATGAAGTCACACCACAAGGTGCAGCAATACTGCTGCAACGTGTGCAGCAAGAAGTTCACACAGGTCACCTCACTCAATCAGCATCTGCAAGCGCATGCCGGCGTCACCGGCTATTATTGCCCCCGATGTCCGGAGAAGAACTTTAAGCTACAATCGCAGCTGCATACGCACATGAAGACGCATGGTTTGGCGTTTCCGTACGAGTGCAGCAAATGCGATGAGAAATTTCTGCAACAATCACATCTCGATCAGCATTTGAAGATGCACGACGagttcaaattcaaatgcgacATTTGCCCCAGTAGCTTTAATCAGGAGTCGCTGCTCAAGAAGCATGTGCAGCGCCATGTGGAGGGTCGCTACTTGAACTGCCCGGTGGCCAATTGTGCCGAATCGTTTGCGGTGCGACAGCATCTATCCAAGCATTTGCTCACCAATCACTCGCATCACGAGCTGCCGCCACCGAAGCGCTCCAAAAAGACGATCACACTGCAATCGCCACAGCAACCGCTCGCCATGATTGGACAGCCGCTATCGTTGCAACACACGACGGGGCAGCGTGGTCGACCGccgaaaaacaagaaagccgcattggcagccacagcaattaAGATCGAGATCAATGAGCCGTTGCACAGTCAGCACATTATCAGCAGTGCCAGCGGCCTATCCATACAGCAGCAGATCAATCAgcacatgcagcagcagcaacaacaacagcaacagcagcaacaacaacaacagcagcagcaacatcttcATTTGCCAATGGGCCAAACGGTCAAGGCGCGCTTTATacccacaaaataa
Protein Sequence: MDTICRLCFQTATLFQVPGYSIPTCVRCSEQLTSNSNFHQTVRGVQDAGAAASVAAVAVAAAAAASTAANDATDAVAAQLTNGNAVAAVLQLQQQQQQQQQQQQQQQQQQQLQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCSYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCSKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECSKCDEKFLQQSHLDQHLKMHDEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLNCPVANCAESFAVRQHLSKHLLTNHSHHELPPPKRSKKTITLQSPQQPLAMIGQPLSLQHTTGQRGRPPKNKKAALAATAIKIEINEPLHSQHIISSASGLSIQQQINQHMQQQQQQQQQQQQQQQQQQHLHLPMGQTVKARFIPTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533229;
90% Identity: iTF_00572743;
80% Identity: -