Dniv011742.2
Basic Information
- Insect
- Drosophila niveifrons
- Gene Symbol
- -
- Assembly
- GCA_035046325.1
- Location
- JAWNOC010000063.1:2036197-2039111[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.41 27 5.4 0.4 2 23 125 147 124 147 0.95 2 13 0.18 12 6.5 0.4 2 23 156 178 155 178 0.93 3 13 3.7e-08 2.4e-06 27.6 2.0 2 23 194 216 193 216 0.96 4 13 0.0063 0.41 11.1 9.1 2 23 483 504 483 504 0.97 5 13 1.2e-06 7.9e-05 22.8 2.8 1 23 510 533 510 533 0.96 6 13 0.00035 0.022 15.1 0.8 1 23 538 561 538 561 0.96 7 13 0.00015 0.0097 16.2 4.6 1 23 579 601 579 601 0.96 8 13 0.042 2.7 8.6 3.8 1 23 606 628 606 628 0.97 9 13 3.3e-05 0.0022 18.3 1.7 1 23 634 656 634 656 0.95 10 13 0.00033 0.022 15.2 0.7 1 23 662 684 662 684 0.98 11 13 3.5e-07 2.2e-05 24.5 2.7 3 23 692 712 691 712 0.99 12 13 2.3e-08 1.5e-06 28.2 1.0 1 23 718 740 718 740 0.99 13 13 1.7 1.1e+02 3.5 5.3 1 19 745 763 745 768 0.88
Sequence Information
- Coding Sequence
- ATGAGCAAATCACCCGCATTGCCCGACAACACGATGACTCAATACGGCGGCGACTTTGATGCGGAGCGCGTGTGTCGCGTTTGCCTGCGAGAAGTGGGCGACTTCTACTTTATCTACGATGAGGCGCCCGTGGAGCAGGGCGCCAACATTGCCCAGATCCTCAACGAGTGCACGCGATACACGTGCGAGCGCTACGACAAGTTGCCGCATCACATGTGCGACACCTGCATCAAGGCGGCCTGTCAAGCGTATCGCTTTAAGCGCGACGCTGAGAAATCGTATCGCTCCTTGGTCGCGATGCTGGGCAGGACGCCAGCATTGAAGCCGAACAGCAGCGAGGTCTGCACACAGACCGAACAGCTGGCCATGCTGCAGTGCGGCATGTGTAGCGAACAGTTCTTGAATGCGCTCGAGTTGCGTTTGCATCGCAAGCGACAGcataagcaacagcagctggagcagctgcagtGTCAGGTGTGTGCGGCACAGTTCCAGCAATTCCGCCAGCTGCGCACACATCTCATCGAGCAGCACAATCAGCCGTCCACATCGCCGCTGCTGCGCCGGCGACCGCGTCTCGAGTGTGGCGACTGCAAGCGCGTCTTCAGTCGACGCGATCATCTGCAGCGTCACATGCGCACAGTGCACAAGGAACGCGATGGTGTCGACGAGTTGGAAGGGGAGCGGTCAATGCACACTCCATGGCCAGCCATCGATGAAGCAACTATGCAAAGCGGCGATGAGCTGGAATCGGCCGCTGTGCTGCTTAACAACTGTGCTGCTGACGATGAGGAGGAGCAGCATGGTCAAGAGCGGGATCCACAGAGTGCGTATCAGAGTCACACGAATCCCATATCGAGCAACGAGGAGGCggatgacgacgacgagctTGAGGCAGAGGCCAAGCAAACGCTGTGGCTGCAAATCAAGCCAGAACCGGAGCTGGAGCTTAATGTGGATGTGGATAGGGATGCGGATGACAAGCGTCGCAAAAAGCCCCAAAGCAAGCAGCAGAAAGAGCAGGAGCAGGTTGAAGGAGCGCATGTGAAAGAGGAGCAGGAGCTGCTGCCCATTAAGCAGGAGCGTCAGCGCAAGGATAGCGTGCAGCAGctggaggcggaggaggaggaggaggacgcGGAGCAGTACGAGGAAGCGCTGCACAGCTctgagggggaggaggaggaggcggaagACGAAGAAGAGGTAGAGGAAGAGGACGACCAAGAAGAAGAGGCCGATGAGAGCGACTTGGAGGAGCTGGACGATGAGGAGGAGAAGCCAAGCTCGGCAAGCGCCGAGACAAAAGTGCAAATTGTGCGCGAATATTTGCAACAGCCAGGCGTAGCAAGCGGAACAGGAACTCAATCGAACTCAGCTGGGGGCaaacagcgacgtcgacggcggAACAAGCAAACAATCGATGCGCAACCAAATCCGGAGAATCGCTGCGACATTTGTCAGCGCACCTTCTCCCGCCACTGCCATCTGTTGCGGCACAAGCTGTCGCATCTGGAGAAGAAGCCGCACAGCTGTCCCCATTGCCCCAAGGCCTTTGCACGCAGCGATCATCTGAAGGCGCATGTCCAGAGTCTGCACGGCAGCAAGGAGCACAAGTGTGTGCTATGCGAGGCGGCCTTCACACGCTCCGATGCCCTCGAGCGGCACAAGCTGAGCAAACACAATGGCGAGGGACTCGATGCCAATAGCGAATTGAAGTTGCAGCTCAGCGAACACACCTGCGAGTATTGCGCCAAGCGTTTCTCCAGTAAAACCTATTTGCGCAAGCACACGCTGCTCCACACCGAGTTCCTCTATGCGTGCAAGAGCTGCGACGAGACGTTCAAGGAGCGCCAGCAGCTGCGGTGCCACGAGAAGACGCACACCGGCCAGCGGAACTTCCTCTGCTGCATCTGCGGCGACAGCTTTGCGCGCAACGATTATCTGCGCGTCCACATGCGGCGCCACAATGGGGAGAAGCCCTACAAGTGTCGCTACTGCATCAAGGCGTTTCCGCGTGCCACCGATCTCAAGGTGCACGAACGCTACCACACGGGCACCAAACCCAATCTGTGCAACACGTGCGGCAAGAGCTTCCATCGCGCCTACAATCTGACCATACACATGCGCACACACACCGGCGAGCGTCCGTACAAGTGCGACCAGTGCCCGAAGAGCTTCAGCCAGAGCAACGATCTCAAGGCGCACATTCGACGCCACACCGGCGAGCGCTACAAGTGTCCGCATTGCGATGCCTACTTCCTGCAACTGTATCACATGCGCAACCATTGCCTCAGCGTCCACAACAAGCACATCGAGACGAAGACGGGACGCCTGCAACGCACCGGGCTGCTCGATGAGCCAACGCACTCGCATTTGACCACTGTTGTGATGCCGCCAGCGtcgaccacaacaacaacaactgtggcaacggcgacgacaacaacgttGGCTACTGTGCCATtgccagcggcagcggcagccacgCCCCTTGTGCACTCGCCCGTCGGCTACAACACATCGTCGCCGGCGGTGGCGACAGTGCAGGATGGATTCGCCAGCAATGTGGCTCCGTCTCCGTCGCCGACGACACCAACACCTTTTGGCGCCTTCAACATAACGCCAGTTGTGATGGCGCATCTCATGTATAACCATGGCGGACAACAGGACAGCCAGCAGAGCAATGCCAGCAATGGCAGCGAACGTGCAACGGGCAAATAG
- Protein Sequence
- MSKSPALPDNTMTQYGGDFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKLPHHMCDTCIKAACQAYRFKRDAEKSYRSLVAMLGRTPALKPNSSEVCTQTEQLAMLQCGMCSEQFLNALELRLHRKRQHKQQQLEQLQCQVCAAQFQQFRQLRTHLIEQHNQPSTSPLLRRRPRLECGDCKRVFSRRDHLQRHMRTVHKERDGVDELEGERSMHTPWPAIDEATMQSGDELESAAVLLNNCAADDEEEQHGQERDPQSAYQSHTNPISSNEEADDDDELEAEAKQTLWLQIKPEPELELNVDVDRDADDKRRKKPQSKQQKEQEQVEGAHVKEEQELLPIKQERQRKDSVQQLEAEEEEEDAEQYEEALHSSEGEEEEAEDEEEVEEEDDQEEEADESDLEELDDEEEKPSSASAETKVQIVREYLQQPGVASGTGTQSNSAGGKQRRRRRNKQTIDAQPNPENRCDICQRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGSKEHKCVLCEAAFTRSDALERHKLSKHNGEGLDANSELKLQLSEHTCEYCAKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRCHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSVHNKHIETKTGRLQRTGLLDEPTHSHLTTVVMPPASTTTTTTVATATTTTLATVPLPAAAAATPLVHSPVGYNTSSPAVATVQDGFASNVAPSPSPTTPTPFGAFNITPVVMAHLMYNHGGQQDSQQSNASNGSERATGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00472490;
- 90% Identity
- iTF_00472490;
- 80% Identity
- -