Dniv013456.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila niveifrons
Gene Symbol
H15
Assembly
GCA_035046325.1
Location
JAWNOC010000068.1:9963947-9981340[+]

Transcription Factor Domain

TF Family
T-box
Domain
T-box domain
PFAM
PF00907
TF Group
Unclassified Structure
Description
The T-box encodes a 180 amino acid domain that binds to DNA. Genes encoding T-box proteins are found in a wide range of animals, but not in other kingdoms such as plants. Family members are all thought to bind to the DNA consensus sequence TCACACCT. they are found exclusively in the nucleus, and perform DNA-binding and transcriptional activation/repression roles. They are generally required for development of the specific tissues they are expressed in, and mutations in T-box genes are implicated in human conditions such as DiGeorge syndrome and X-linked cleft palate, which feature malformations [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 7.5 1.1e+04 -4.0 0.6 114 126 61 73 33 90 0.54
2 3 6.8 9.6e+03 -3.8 1.8 72 88 188 204 167 224 0.47
3 3 4.9e-73 7e-70 234.5 0.0 1 182 293 486 293 486 0.96

Sequence Information

Coding Sequence
atgcttttaagcAATCAACCGGCAAACACAAAGCCACAGCAGCCGTCGCCGACACCGCCACAAAGCTTCAAATcgaagctgcagcaacaaatcgcaacagcagcagctgccgctaACGCCGTaacagccgcaacagcaacaacaaatattgcCAACGGTCacagcaatcacaacaacaacaacaacagcattatcaatcatcatcatcaccaacatccacatcatcatcatcagcttcaCCATCATCAGCATAATATTTCCTTTGCCACGGATTTCTCAATTGCCGCGATTATGGCGCGCGGCGGAAACGCCTCAAGCAGCCGCGAGCCATCCGAAAGGAGTTTGAGTCCGCTGTCTGTGGAGCGCTATTCAACGCAGGATGCGGACGATGATGTTGACGTTGATGTGGTCGACTGCAGTGACTCGgaaacgccaacgccaacggcagcggcaacagcagccgcagcagcgacggcagcagcagcggcggcggcagcagcagcagcagctcagcagcATGCACGTCATGCATTGCGTGttgcacaacagcaacagcagcagcagcagcagcagtcgaggcaacagcaacagacacaTCCCCATCAACATGCAACGCCAAACaagcaacgccaacaacacaatcaacaacacaacaacagcaaatcgaGCAGCCATCGAGGGCGTGTTGCTGCCACACCAACTGCAGCTGGAGtcggagctggagctggagttggagctggtGCTGGCAGCACGCCCTCTCCGCCCCCCAGCGAGCTGCACGCTGAAGACGAGCGCCTGTCGCCTGAGGAGCCTGCGCAGCTGCCCACGCCCAAAATTCTGGGTTCGTGCAATTGCGATGATCTCATGCCCGTGCAATGCCATCTGGAGACAAAGGAGCTGTGGGATAAGTTCCATGAGCTGGGCACCGAAATGATCATCACCAAGACGGGCAGGCGCATGTTCCCCACGGTGCGTGTTAGTTTCTCGGGCCCATTGCGGCAGATACAACCACCGGATCGTTATGCCGTACTGCTGGACATTGTGCCGTTGGATTCGAGACGCTATCGGTATGCGTATCATCGCAGCTCGTGGCTGGTGGCTGGCAAAGCGGATCCGCCGCCGCCCGCTCGCATTTATGCACATCCCGATAGTCCCATAAGCCCAGAGGCGTTGCGCAAACAAGTCGTCTCCTTTGAGAAGGTGAAGTTGACAAACAACGAAATGGATAAGAGCGGACAGGTCGTGCTGAATTCTATGCATCGGTATCAGCCACGCATTCATTTGGTTCGTTTAAGCCATGGCCAAAGCATACCCGGCAATCCCAAGGAGCTGCAGGATATGGATCATAAAACGTTCGTATTCCCAGAGACGGTATTCACAGCCGTGACGGCCTATCAGAATCAATtgattacaaaattgaaaatcgattCGAATCCGTTTGCAAAAGGATTTCGCGATTCGTCGCGTCTGACTGACTTTGATAGGGATCCCATGGATTCATTCTTTTTCGATCAACATATGCGCGCTGCCCCATTGCGTTTCTTTCCGGATCCGCTAATGTCACAACTAACGCCACAGGAAGCCGACGCCGCTTCGTTGGCGCTGCTGGAGAAGGCGCGTCAgcatttgcaaatgtttgGCCGCTCACCGTACACGGAAATGTTGCTGCCCCATCTGTATCAACGTGCCGCACCGCCAGccccgccgccgccgccgccctcAGCCCTGGGCGCCTTTCAGCTGggcatgtggcagcaacagtggcCACAGTTGACCGCCGGTTTCCTTGCCAGCGCCAATCAGCAAGCGGCcttcgctgctgccgctgctgctgcagctggcgcCAGTCGAACGCCACCACCCACAATAGCAGGAGGCGGCGGGGGGGGAGGAGTTGCGCCAGGAGCTGTTTCAGCACCTCCCGcgcctgccacgcccacatcgTCGTGCGGCTCGGCGTCGCCGGATTTGCGCATCAAGACGCAGCTGGCGCACTATCCGCAACGCTTCAGTCCGTATCAGGTGCCACAGCATCCGCAGTCTGCCACATCGCCGGCGCCATCAACACGCGCCGAGAGTCCCTAA
Protein Sequence
MLLSNQPANTKPQQPSPTPPQSFKSKLQQQIATAAAAANAVTAATATTNIANGHSNHNNNNNSIINHHHHQHPHHHHQLHHHQHNISFATDFSIAAIMARGGNASSSREPSERSLSPLSVERYSTQDADDDVDVDVVDCSDSETPTPTAAATAAAAATAAAAAAAAAAAAQQHARHALRVAQQQQQQQQQQSRQQQQTHPHQHATPNKQRQQHNQQHNNSKSSSHRGRVAATPTAAGVGAGAGVGAGAGSTPSPPPSELHAEDERLSPEEPAQLPTPKILGSCNCDDLMPVQCHLETKELWDKFHELGTEMIITKTGRRMFPTVRVSFSGPLRQIQPPDRYAVLLDIVPLDSRRYRYAYHRSSWLVAGKADPPPPARIYAHPDSPISPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGNPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMDSFFFDQHMRAAPLRFFPDPLMSQLTPQEADAASLALLEKARQHLQMFGRSPYTEMLLPHLYQRAAPPAPPPPPPSALGAFQLGMWQQQWPQLTAGFLASANQQAAFAAAAAAAAGASRTPPPTIAGGGGGGGVAPGAVSAPPAPATPTSSCGSASPDLRIKTQLAHYPQRFSPYQVPQHPQSATSPAPSTRAESP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00601809;
90% Identity
iTF_00589554; iTF_00472371; iTF_00509108; iTF_00537521; iTF_00614196; iTF_00520640; iTF_00595254;
80% Identity
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