Dnik013122.1
Basic Information
- Insect
- Drosophila nikananu
- Gene Symbol
- -
- Assembly
- GCA_008042635.1
- Location
- VNJV01007407.1:25350-30656[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0064 0.72 10.8 0.5 2 23 155 176 154 176 0.97 2 13 0.0017 0.2 12.6 4.8 1 23 400 422 400 422 0.98 3 13 3.4 3.9e+02 2.3 2.3 1 23 428 451 428 452 0.92 4 13 0.28 32 5.7 2.7 1 23 474 497 474 497 0.93 5 13 0.0039 0.44 11.5 3.9 3 23 813 833 812 833 0.92 6 13 0.041 4.6 8.3 1.4 1 23 839 862 839 862 0.98 7 13 0.0024 0.27 12.2 0.4 1 23 942 965 942 965 0.97 8 13 0.0023 0.26 12.2 0.8 1 23 1154 1177 1154 1177 0.93 9 13 0.016 1.8 9.6 4.5 1 23 1189 1211 1189 1211 0.98 10 13 5.2e-05 0.0059 17.4 0.8 2 23 1217 1239 1216 1239 0.95 11 13 0.0026 0.3 12.1 1.2 3 23 1248 1271 1247 1271 0.90 12 13 5.4e-05 0.0061 17.4 0.2 2 23 1277 1298 1276 1298 0.95 13 13 0.056 6.3 7.9 0.2 2 23 1304 1326 1304 1326 0.94
Sequence Information
- Coding Sequence
- ATGGCATTGAATAAACGGATTAACCCAAACCCGGACGCCCTCACGGGCGTCACGGAGTTGAACTACAAATTTGCGTGTCGCTGCTGCCTGAAAGTGGACGCCGAGCTCATTAAGCTAGAATCTGTGTCGGTGGCGCGTAGCCTGGACTCAGCCTGCGAGGAGGATAAGGTTTCGCTCCTGCGGTGCCTCCTCTTCTGCGTACGCGCTGAGAACGCGCCGGAGCTGCCGCCGTACATCTGCGTAGATTGCAGTACGAGTCTGCAGGTCGCCTACTACTTCCTTCAAAATGCAGTACGTGCCCACGAGATCCTTTGCCGCAAGCTGTGTCCTGGAAAGCTACGGAACGCGGAGGGCAAGCGCTACAATGGGGCTGTGGCCCAGCGCTTGCAACCATCGCCGTTTTCGAAGGAGGCGGCGACGACTTCGGGGGACAGGGCGAGGCCTCCGAAGACCATGCGGCAAGAGTGCCAGGTGTGTGGCGACATTTTTTTCAGTCGCATGGAGCTCAAACAGCACCTCCGACAGCACACAGacGGAATCTCTTACCACTGCAAGATGTGCAACTTCACCACGCTAAAACAGCGCCAGCTGCTAGATCACTACCGCTGTGATCACGCCATGACTTCCAGTCAGGCGGAGGAGCACGTTAAAGCAAGTCCACTCCCAGTATCCCCCATTAAGGAGGATGAGGTTAAGGCAGTGTGCACGCTTGAAGACATGGAGCTGCTTATACCCACGGTGCTCACGCCGGACGACTACGCACAGCCCACGATTGATTCGGAACAGCTGCGCGACCTCGAGCAGCAGTTGGCAGTCGGCATGGGCGACGCGGTGGCCGGAGTAGATAGCCTCACGTCCACATTGCCGCCCATGGACACGGCGCATAATGTCAGCATCGGGACGGAGTATCTCGTTCTGCCAGATGGATCCCTGCAGCAGATCAATGGAGGCGGCGTGGTCATTGAGTACATTGACGACAGCAAGCTgcagccaccgccaccgccacctccTCCCAATCCTCCTCATATCAACATAAACCTGCAAAATCTCCTCGGCCCCGAAAACGACGCTATGGATATCGATGTCAGCGAGCTAATCGTCGAGGATATGATGAAGATACAAAAACCCACCATTTCCACTGTTCCTCCCCACCAggccaagccaaagccaacAGTTGGCGGATCCCCAAACTACAAGCACAAGTGCAGTTTATGTCCCAAAACGTTCTGCTCTGTACCACGCCTAAAATCTCATCAGTTAACCCACAGCAATTTACCCAAGTTCTTCTGCGACCAGTGCGACTTCTACTCGCTGCGCAGTGTCGATCTCATCGAGCACTACAAAACAACGCACCACCGGGTGGATGAGAACGGTGTGACCAGCCAGGACCCAGCGCCGGGGTCGGAAGAGATGGGCGTCTATTCGTGCGACATGTGCCTCTTTGAGACACGCTCCTGCAGCCAGCTAAGGGTTCACTACACGGAGCAGCACGAGATTCAGCCCACGGAAGTGCAGCTGCGTCCTAGTTGGACAACCAATGGTGGCGATGGATTGAACAAAAAGGAGCTGCCATCGTCAGGCGGGCAGCCAGAAACCGCCGAACTGCCGGTGGCCATTAAATATCCGCCGCTAGTTGTGGATGCGCAGGTCCCAGTGGAAGTTCAAGTGCAAGTGCAACAGCAAATGCAACTACAGCAGCAAATGCAAGTGGAGCAACTACAAGTGCAGCAGCCAGTTCAAGTGCAGCATCAACAAGTGGTGGTCAACACACCAACAACGGTCATCACTCAGACGAGCAACAACGTAAATGTGCTGGTGGATACCACGCCGCTCTTCTATGCGTCCGCCGTTTCCAGTGCCGTGCAGGCAGAGCCAGTGCCGGTGCATACCATGCCAGTGCAGACCATACAAGTGCCGGTGCAGACCATACCAATGCTTCCAGCGGCTGTGGGGGAGCCCACCAACGAGAATAACAGCAATGCATTCGACATCCAAAATCCATTTCCACAAATCCCACCAGGCGATGAGCAGGTCAACGAACCCGTTCACGTTGAGCCAATTCCGGCGGCAAATACTTCCAATATTTCAATGTTTGGCGATATGCAGGATTTCATTGATAACACCGATGTGGCTGCTATATGCACGATACCAGCGGACGATATGCCCGTGGTGGATGGCGACGATATTGTGatcgataataataatatcagcCTGGACTTTGATGCCGAGAATCTGTTTGAGGAAttcgaggacgaggacgaggcgCTGGCAGAGGACGAAgaagacgaggaggaggaggaggaggatgacgCGGACAATGACGATGAGAATGACAACAACGATGCTGCCACAGATCAAAATCTTCTGCTTACCAGTGACGATGATGACGTGGACGACTTTGACGATGAGCAATCGAAGCATCTGCAAAAGCCCTACTGCATTCATTGCAACAAGAAGTTTACCAGCCAATACAAGTTCGAAAACCATATGTTTGTCCATCGGGGCCTAGCACCATATCGCTGCGAGCTGTGCACCAACCTCTACAACATGAAGCGCCTGCTTATCAGGCACTACAAGACCGTGCACAAGCGAATGCCTACCAGGGATATGGTCCAGGCCAAGGGCGATAAGGTACTGGTGGCCCGTACTAACATAGAGAAGCTGTATCTGGATTCCATCAAAAATCCCATGGTCATGTGTGCCAAGTGTCCCTTTGAGTGCGAGGCGGATGGAGAAATGCGAAAGCATCTGAATGCCCATCACGGCATTAATGATGGACTGTCGATTCATGCCAACGAGGTCTTCATAATACGCAAATTGCCGTTCGAGTGTCCGCGATGCATTCGATCGTTTGCTGCCAAGGGCACGCTCACCCGCCACCTGCAGCGCAGCCATTTGGTGGACACTATTATTGAGATGCAAACGCCGCATTCGTCggcggccaccaccaccatcacaacaacaacggccaCTATAGCCGGGCCAGTGGGAGATAAAGAATCTATTAAGGACGAGATGATAATGACGACAACGACGGCTGCTGCAGGCAATGAACTGAGAGGAAATCTGGATGATGGAAGAGCAGCGCCAGTAAAAAGGGAACTGGTCGTACCAGATGAGGATGTGGATCCGGTGACGTTGGACGCAGCCACTGCGGCGACTACAGCTGCCATAGCAGCAGCAATATCATCCGCATCCACATCGCCCAACGCAACAACAACCTTGGCGGCTTCCGGATCCAACCTATATCCCACTCCCACGCCGTTTGATTTCGACTATGACCTAATGGGCAGCGATGCGCAGCGATCCCAGGTCTCGACACCCACCTCCAATCCCCAGCTCAGGCCGTCCGGCAGTGGTCTGCTCAATGGCAGCGACAAACTACTGACCACCGCAGCCATGGCGCCCTTCCCGACGAAGGGTCTGCGCTCCACCAGACGGCCGGCCCATAGTTCACTACATGTGTGCAAGCTGTGCAACAAGTCCTTTGACGAGCTGGGCAAGCTGGTCAAGCACGAGATGGAGATGCACTCGAATACGGAGCCCTCGCGTTGGGGTTACCAGCACAAGTGTTCCATCTGCAGCACCAGCTACCGCACGCTGACACTGCTCAAGTTCCACATGCAGCGGCACGTTACTCGGAAGTCGCAGTGCAGGCTCTGCCCGAAAACTTATGCTACCAACGCGGAGCTTGAGAAACATATGAAGTTCAAGCATTGCCGCGAGAAGTTAATTGGCCCGTGTGGAATTCTTGGCTGCGGGAAGATGTTCGCCTTCAAGCATCATATGGTGCGGCATCAGAACGCCTCTCACCTGAAAGATCCCCTTATCTGCGAAATTTGCAATAAGCAGTTTGTGAACATGGCGCTCCTGAGAAAGCATATGATACTGCACAAGGGTATTTCAGCCAGGTGTCCCGAGTGCGACAAGCCATATTTGCGGCGCGGAAGACTTCTGAGTCATCTACTGAATATTCACAAGATACGCCTAACCGACGAAGAGACGACCGCCCTCATGAGCGGCACTAAAGAAGCCCCAAGCCCGTCACAAAGCTCGACGCAAAGTCAGCCGCAAAGCCGTAGGGGGCAACTGGGGCGCCGCAAGAACTTGAACATGAACGAAACGATGGTCAAGGAAGAGACGCATGCGGATCCGGTtacaacagcggcagcagttcTTTCCAAATAG
- Protein Sequence
- MALNKRINPNPDALTGVTELNYKFACRCCLKVDAELIKLESVSVARSLDSACEEDKVSLLRCLLFCVRAENAPELPPYICVDCSTSLQVAYYFLQNAVRAHEILCRKLCPGKLRNAEGKRYNGAVAQRLQPSPFSKEAATTSGDRARPPKTMRQECQVCGDIFFSRMELKQHLRQHTDGISYHCKMCNFTTLKQRQLLDHYRCDHAMTSSQAEEHVKASPLPVSPIKEDEVKAVCTLEDMELLIPTVLTPDDYAQPTIDSEQLRDLEQQLAVGMGDAVAGVDSLTSTLPPMDTAHNVSIGTEYLVLPDGSLQQINGGGVVIEYIDDSKLQPPPPPPPPNPPHININLQNLLGPENDAMDIDVSELIVEDMMKIQKPTISTVPPHQAKPKPTVGGSPNYKHKCSLCPKTFCSVPRLKSHQLTHSNLPKFFCDQCDFYSLRSVDLIEHYKTTHHRVDENGVTSQDPAPGSEEMGVYSCDMCLFETRSCSQLRVHYTEQHEIQPTEVQLRPSWTTNGGDGLNKKELPSSGGQPETAELPVAIKYPPLVVDAQVPVEVQVQVQQQMQLQQQMQVEQLQVQQPVQVQHQQVVVNTPTTVITQTSNNVNVLVDTTPLFYASAVSSAVQAEPVPVHTMPVQTIQVPVQTIPMLPAAVGEPTNENNSNAFDIQNPFPQIPPGDEQVNEPVHVEPIPAANTSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFEDEDEALAEDEEDEEEEEEDDADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIHCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVARTNIEKLYLDSIKNPMVMCAKCPFECEADGEMRKHLNAHHGINDGLSIHANEVFIIRKLPFECPRCIRSFAAKGTLTRHLQRSHLVDTIIEMQTPHSSAATTTITTTTATIAGPVGDKESIKDEMIMTTTTAAAGNELRGNLDDGRAAPVKRELVVPDEDVDPVTLDAATAATTAAIAAAISSASTSPNATTTLAASGSNLYPTPTPFDFDYDLMGSDAQRSQVSTPTSNPQLRPSGSGLLNGSDKLLTTAAMAPFPTKGLRSTRRPAHSSLHVCKLCNKSFDELGKLVKHEMEMHSNTEPSRWGYQHKCSICSTSYRTLTLLKFHMQRHVTRKSQCRLCPKTYATNAELEKHMKFKHCREKLIGPCGILGCGKMFAFKHHMVRHQNASHLKDPLICEICNKQFVNMALLRKHMILHKGISARCPECDKPYLRRGRLLSHLLNIHKIRLTDEETTALMSGTKEAPSPSQSSTQSQPQSRRGQLGRRKNLNMNETMVKEETHADPVTTAAAVLSK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00524667;
- 90% Identity
- -
- 80% Identity
- -