Basic Information

Insect: Drosophila nikananu
Gene Symbol: HIVEP2
Assembly: GCA_008042635.1
Location: VNJV01015521.1:65295-73437[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0011 0.13 13.2 0.2 1 23 249 271 249 271 0.98

2 8 0.00025 0.028 15.3 2.9 1 21 277 297 277 301 0.89

3 8 0.061 6.8 7.8 0.1 1 19 925 943 925 946 0.93

4 8 2.2e-06 0.00025 21.7 2.0 1 23 1649 1671 1649 1671 0.99

5 8 9.4e-06 0.0011 19.8 5.3 1 23 1677 1701 1677 1701 0.92

6 8 0.00011 0.013 16.4 2.6 2 23 2165 2186 2165 2186 0.97

7 8 0.00064 0.072 14.0 1.2 1 23 2192 2216 2192 2216 0.91

8 8 0.0021 0.23 12.4 2.7 1 23 2237 2261 2237 2261 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0011	0.13	13.2	0.2	1	23	249	271	249	271	0.98
2	8	0.00025	0.028	15.3	2.9	1	21	277	297	277	301	0.89
3	8	0.061	6.8	7.8	0.1	1	19	925	943	925	946	0.93
4	8	2.2e-06	0.00025	21.7	2.0	1	23	1649	1671	1649	1671	0.99
5	8	9.4e-06	0.0011	19.8	5.3	1	23	1677	1701	1677	1701	0.92
6	8	0.00011	0.013	16.4	2.6	2	23	2165	2186	2165	2186	0.97
7	8	0.00064	0.072	14.0	1.2	1	23	2192	2216	2192	2216	0.91
8	8	0.0021	0.23	12.4	2.7	1	23	2237	2261	2237	2261	0.92

Sequence Information

Coding Sequence: ATGGAAAATGCAAGCACCACAACAGCCAAGCATTACAAGACCGCAGGCAAACAGTACAAGACCAATAAGATGGCAGCCGTCAACAGCAGCTGCAATAGCAGCAAGGAGCCAGTGGCCATTGCCACAAACAACCATAGCAACACGCCCGCCACCGATGGACCCGCCCTCGGGGATTGCTCTAGCAATATTTCGAGGTATCTTCACAAGAAGTTTAAGCGTCTGGCCAGCACCACCGACGTCGAGAGCGGGAATGCCACGGCGAACGGTGGCCAATTGACCTCCGCTGATGCCGGTATGCGTACCACATCGCTGTCCTCAAATAGCTCATTGTCACCTCCACCGCCGACGGCTATGGTCGCCAATGGTCACCATTTGACCCAACAGCTAGCCCAGCAGCCTCAGCAGCCGGCCGCAGCCatcgccaccaccaccacacatGAATTCAGTGCCAATTTTGTAAATAGCAATCATGTCAATGCCATTGGTCATGAGGAGAGCAATAGCCACAAAGCGGCGTTGAATGCGAGAACGCGAACGCCGCTGACTaacagcagtagcagcagcagcggcagcaactaTGCGGCGAATGCCACCCTGTCGCCGGCAAACTTTGCCCAGCACCAGCAACTGACGCAGCCAACAGCGGGAGGCGCTGGGATCGCAGGCGGAGGCGGGATACCAGGCGCAGGTGGAGGCGGTGGAGCAGcactagcagcagcagcagccggcgaGAAAGCCGGACGCTATGTGTGCCCATTCTGCAATCTGATCTGTGCCAAGCCCtcggtgctggagaagcataTACGCGCCCATACCAACGAACGGCCATATCCCTGTGACACCTGCGGCATCGCCTTCAAGACCAAGAGCAACCTGTACAAGCACTGTCGCTCCCGGTCGCATGCGGCAAGAGCAAGGGGCTTGGAAGTGCCCGCCGATGCCGACGACGGGTTGTCCGATCAGGATGCTGAGCTGAGCAACAGCAGCTCGGAATTGCCAAGTCGCGCTGGTTCGCCATACGATGAGCCCATGAGTTCGCCCACACCCTCACCTTCCACACTGTCTGCGGCCAAGAGCGCCTACAtccagcagccgccgccactTCCGCAGCATATGCAACAATTGCCGCTGGGCTCGCCGGCTGCTGGCACCTTGCCGCCCACAACGGCGGACAATATCCATTCGGCCACTGCCCAGCATCGTCAGTCCATTGACTACAAGCCATATAAGCCCAAGTTCCATAATGCCTCCTTGTATGCCCCCGGCAGTGGCAAGGagcaacagctgcagcagcagcaacagatgcagttgcagcagcatcagcagcagcaacagcaacagcaacagcaacaacagcagcagcaccagcaacaccagcaatTGGCCCAGCAGAAGCTATCCATTCAGCTGCCATTGGTACAGCAGCAGCCATCGCTTGCACATCCCACGCTCTCGCCCAGCACacagatgaagatgaagaacCACATCAATTCGCACCAGCTTCAAATCCAGCTGCAGCACCAGTTGCATGCCCAGCAAACCCTCTTGGCCTCCATGCCGCCGGTGCCACCGGCCGGAGTCTATTACCTGGGACAGCCGCCCTACTATAACCAAGATCCAACAGCGGCGGCCATTCATCACAATGCTTTGGTCTTCCAGCaattgcaactgcagcagaTCCACCTGgcgcatcagcagcaacaacagcaacagcagcagcaacactcTCCTTTGGTAAAGCCCCCGCCCCCAATACAACAGCCACCAAGTCTTCCGCCTCAGCagCTGGTGCGAGCCAATAGTCAGGTTTCCAATGTGACACCAGccccggccacgcccacgccggCTGCCGCCGCCAATCTCAGCACTTTTGCCAGCTCCAGTGGTAGCATGCAAGTGAATGTGGCCAAGGTGCAGGAGCACATTTCCAAGTTGATCTCACAGAACGAGGCTATAGTGGAGAACAAGGAGATTCTGCTGCAGAAGAAGTACCCCAAGCAGCTGAATCGTTCCCGTAGCTTTAACAATGCCAATAGCACGAATCATGCGGCCaatgcggcggcggcattgcATGCGAACAGCAACAATAGCCACAATCTGAGTGCACAGATGCCGGAGCGAGAGACCAAGGTGAATTTGGCACAGGCCATAGtccagaaacagcagcaacagcagcagcagcagcagcagcagcagcaacaacagcagcaacaacagcagcaccaacttcagcagcaacaacagcaactgcagcagcaatcGGCGCTCGAACAGCAGCACTATATGTATGCActtcagcaacagcagcagcagcagcagcaggagagtcagcaacagcaaccacaacaactACTGGAGCCGCCAAATGGTTTAATTAAGCGGAATAGCTACAAGCCAGCATCAATCCCACCGGCACCTGtcaagcagcaacagcagcagcagctgccgccgccaccctcACCGCTGCCCATGCAGACGATGCAATATCGCCAGGATCCTGCAACGCCAGTGGCTAAAATGGACCAACCGACCACGGGTGTGCATGTGATGCCTTTGAACCTGTCAGCGAAGCCGAAGCCCGCCGTGATTACAGTACCCGTTAGCTCATTGTCGAACTGTAGTGTGCCGGCGACGCCCTCCACTTCGGCCGGTTCGTCGGGCAGCTCCAAGGCGGCACCACCGGCTggacaaattaataattcaatcaTCAAGAACCTGCTGTTGAATGCACGTGGATTGGCGGTCCCAATTGGCGAGGGCGACGATGCCGTTTACTCGTGCCCGATCTGTGCCAGCGAATTCCGCAGTGCGGACAAGCTGAAGCTGCACAACAGCACCTACTGCCAGGACGCGAGTTCCAGTGCTCCCATGAGTCCAGCCTCGTCGCCCTTCCGCTCTAACTCGATCTCGTTAAGTCTGCCGGAGCTGAAGAGTCACATGGCCAACTCGAAGAATCCGCTATCGCTGGCCAAGTTGGCCTGGTCGCAGCTAAAAACAAAGCGAAGCAGTTTGGTGGCAAGTCGCCTGAATGCAGCTCAGACGCCAGCGAGAACTTCAACTGTGACAGCTCCCACCGCAACTGCTCCTGCCACAactcttgctgctgctcctgccccgGCACCGGCACCTGCACCTGCACCGGTTCCTTCGAGCCTAGTTCCCGCGCCACAACTGCCCCTTGAGGGACTCCGCTTTGTGGATGCACCACTGCCATCGCCTGGTCCCCTGCTTGGCAAGACGCCCTTGGTGGACTATGCACAGCAGAATGCGCCACGCAAGGCTCAGGACTCGGTGGTCATTACGAAAATGCACGAAGATCGCCAGTTTGCCAGCTTGGATATCGAGGCTCCGCACGCCAAACGTGTGAAGTCCAGTGATTTGGCTGCATcggcttcctcctcctcgcaaGGCTTCTCCTTTCCCTTCACCAACCACAATACCAACAGCCTGCCTGAGCCGCAGCCCGTCAAGGAGGAGCGCCTGCGCAGGTTTACATCCTCAGGGGGAACAATGATTCCCATCTCGGAATGCCCCGACTTGGAGAACAGTCCCAAGATGATACGTACACCGTTGCTATCCGGTGGAAGCTTCCAGGAGGTTTCGGCCAAGGTAAACGATGCAGGATCCAGCAAGGAGCGCAAACGCTTGGCCCTCATCAGTGGAAGTGGACTGCTCGGCGTCAGTTCCGGTCCACAGCACTTTCAGTTTCCGCCCATCAACTCGATAACTGCCTTTAATCCGTTGACATTGCCACCGATGAGCGCTGGAGGCGAAAAGTCCACTCCCGTAACGCCCATTCCCTATGTGCCCGGGATTCCAGGGCCAGGAAGTCTGACTCCGCAGATGCCACTgcttccgccgccgccacagcagctgcagttgccGGTTCCTTCGGGCCGTGGACGTAGCCCGAATCGCAAGCAACCCAGTCCGCTCCTAATGGGAGCTGCCGTTGCTGGTGAACTCAAGGCTCTATCACCCTTTGGCGGAGTCCAGAATTTGCCCAGCGAATTCAGTCGCCAGCCACCAACTCCCGCCCAGAGGCAGGCGCTGCAGTGGAACAGCAAGGAGTCGACGCACAAGAAGGCGCCATTCAACTTTCTGCGGATGGCGGATAATGTCAAGGCCACCACAGAACCGGAAGTGCGACACTTTAATCTAGACAATGTGATTGCTGCGAAACAGTCAGAGGCGTCGCCACTGACACCACTCCACGTGGAGACACCCAATGGGAGTGCTGCGGAGGAAGCAAGTCAGAGTACCTCAGCCAAATCAAAGTTCCTGCGACCCACTAGCTTACCCCTGAAGCCGGGAACATTTACGCCAAAGCGTCATCATGGGATTACACCGACGGCCAACACCCTGCCGCTAATCTCGCCAGAGACCCCGCGTCCCTCCAAGTCCTGCGTGCAACTATACCTCAACGGCCACGCCTACACCTACTTGGGCCTCAAGTGCAGCACAAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACATGCTGTCGATGTATAGCGTGTGGCAGGTGTGCGAGGAGAACCAACCGCATCCCCTGGGATTCAAGCTGAAGAAGGTGATGTCGCTGTACGACTCCCGGCAGAGGATGCTGGGTAATGGCAGTTCCACCGCCATGGCTGGATCGGGAAAACTGAGCTACAATGTGGTCTCCTCACAGCAGACAGTGTGCTCCACATCAACGCTGGCCAGTGCCAGCTCCAGTGCCTTCTATCAGAATCAGCTGAAGACATCGCCCTCAGCAGTCACTGTGTCGGTTTTGAGCGAGGCCAATGTGGCGGCCAAGGCGAACGAGGAGGAGGCGCAGGCCAAGAAGCTGGAGACCAGTCCCTCGGGACAACCTCTAGTGGGTGGCTACGAGTCGCACGAGGATTACACCTACATACGGGGCCGGGGACGTGGCAGATATGTCTGCTCCGAGTGCGGAATCCGCTGCAAGAAGCCCTCGATGCTGAAAAAGCACATTCGCACGCACACGGACGTGAGGCCGTTCACCTGCAGTCACTGCAACTTTAGCTTCAAGACCAAGGGAAACCTGACCAAACACATGCAGTCGAAAACGCACTTCAAGAAGTGCATCGAACTGGGCATTAATCCAGGACCCATGCCTGCCGATGGTGAGTTCCTGGATGTGGACATGGACTTTGATCAGCAGTCGTCGACCTCGGCAGGAGGACGCACATCCTCAATGGCGGGAGAGTCTGATTCGGATGACTACAGCGACAATGAATCGGAGAGTAGTGACACTGACGAGTCCAAGTCCCGGTTGAAGGAGCACGAGGCAGCCAGGTGCCTGCTGTCGCTATCGATGACGCCGCCCATTCCACAGAGTGTGTCGCCATATCCTCAACTGCTACAGGACACACCTTTGCCAGCTGCTAGTCCCGCGAACAGCATCGGATCCTCGGGCTCTTTGCCCAAGCGTTTGGTGTGCTCATTTACCTCGCCGAAGCCACCGTTTGACTATCAGAAGCAGGAACAGTATTACTCCAATCCCGAGGAGTCTAAGCCTAAGCGCAGCGCGGCCAGCGAGGAGAGCGCTCCCATGGATCTGACTAAGCCGCGTGGCTCCATGTCCGCCGCGGTCTCGCCATCGCCAGTGCCAGTGCAGCCACCTGTGCACGATTTGCCCAAGTCGCAGGCCCAGCAAATGCACGATGTGATCTTCGGCAGCTCCGGCAATGAAAGTGGCTTTATGAAGACCTTGATCTCAGTGTCGGACAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCCAAGCACGAGGCCGAGGGCGAGGATGTTCTGCTGCAGACCTACATCAAGGAGCAGGCGCTGCATCATGCTAAGCGGAAGCAGAGTCAGTTCAGTGGCAGCTATCTAATCAATACCTTGTTCTCCACGACGTCCACGGTGATGagtagcagtagcagcagtAGTGGCAGTGGCAACCTGTTGACCACCAGCAGCCGACCAATTATGACCATTAATGAGGTGCCCAGCATCGAAGTTCATGAGGTAAAAACGCCAGAGGCTGTGGACTTGCCAGCCATACCTCCTGTGGTTGCTCAACCAACTCCAACACCCACCctcacgcccacgcccacaccTACTCCCATTCCTGTGAAGCTAGTCCAGGAAGAAAGCGAAGAGTCGGATCAGGAGAAGCCCATGGTAGAGCCCCATAATGCCAATCTGCCAGCTGCAGTGCAGCAGAAGGATGCCAATGATTTTAGCGGAGTCCTCGGGCATCCGCAGTCCGGAGGAGCCGCCACAGTGGTCACATCAACACCTGCTCCCGTGGCCGTGTCCTCGAACACGAACACGACTCAGCCCACGCAGCGTACCGTGATTGTGGGCGAGGATGGCTTCAAGAACTCCACGCCCAGCAGCAAGAGCAGTGATCTCCAACCGCATGTATCCTATGCCCGAGCAGTGCCAGTTCCAGCTCCCATTGCCAGCGATGTCCGGCCCACCTGCTCCATCTGCGCCAAGACGTTCCAGCGCCAGCATCAGCTAACCCTGCACATGAACATCCACTACATGGAGCGAAAGTTCAAGTGCGAGCCATGCAGCATCTCCTTCCGCACGCAGGGACACCTGCAGAAGCATGAACGTTCCGAGGCGCACAAAAATAAGGTGATGATGACGTCGACATTCGGCGTTCCCACCACCTCCAATCCACGGCCCTTCGAGTGCACCGATTGCAAGATCGCCTTTCGCATCCACGGCCACTTGGCCAAGCATCTGCGCTCGAAGACTCATGTCCAGAAGCTGGAGTGTCTGCAGAAACTGCCCTTCGGCACCTACGCGGAGATCGAACGCGCTGGCATCAGCCTCACAGAGATCGATACCAGTGACTGTGAGAACTCACTGATATCTCTGAAGTTGCTGGCCCAAAAGCTGCTGGAGAAGGATCCCAATAAGCTGAGCGGCTACACCACACCGTCCGGCATGATGCAGCTGGCCCAGGATCCGGCGAATCCTGCCTCGCAGGATAGTGCCTCCGAAGATGGATTCAGTGCCGCGGTGGCCATAGCCTCGGCCATTGCTTCGCTGGACAATGACAGTGCCGGCAATACACCGAAGCGGGCCAGCTCGATGTCCGAAGACGAATCGGTGGCCAATGGCCTGAATCACAACCTGAAGCGTCGTTTGCCCGGCAGTTTCAGCAGCACGGGTGAGGAGAGCGATAACCCAACCGAGGGCAATGGCGGCGAGAAACGTGCTCGTTCCAGCCAGGACCTACCGGTTGCGGTTCCCGTTGCTgcctcggcggcggcggcggccagcaACTGA
Protein Sequence: MENASTTTAKHYKTAGKQYKTNKMAAVNSSCNSSKEPVAIATNNHSNTPATDGPALGDCSSNISRYLHKKFKRLASTTDVESGNATANGGQLTSADAGMRTTSLSSNSSLSPPPPTAMVANGHHLTQQLAQQPQQPAAAIATTTTHEFSANFVNSNHVNAIGHEESNSHKAALNARTRTPLTNSSSSSSGSNYAANATLSPANFAQHQQLTQPTAGGAGIAGGGGIPGAGGGGGAALAAAAAGEKAGRYVCPFCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYDEPMSSPTPSPSTLSAAKSAYIQQPPPLPQHMQQLPLGSPAAGTLPPTTADNIHSATAQHRQSIDYKPYKPKFHNASLYAPGSGKEQQLQQQQQMQLQQHQQQQQQQQQQQQQQHQQHQQLAQQKLSIQLPLVQQQPSLAHPTLSPSTQMKMKNHINSHQLQIQLQHQLHAQQTLLASMPPVPPAGVYYLGQPPYYNQDPTAAAIHHNALVFQQLQLQQIHLAHQQQQQQQQQQHSPLVKPPPPIQQPPSLPPQQLVRANSQVSNVTPAPATPTPAAAANLSTFASSSGSMQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANSTNHAANAAAALHANSNNSHNLSAQMPERETKVNLAQAIVQKQQQQQQQQQQQQQQQQQQQQHQLQQQQQQLQQQSALEQQHYMYALQQQQQQQQQESQQQQPQQLLEPPNGLIKRNSYKPASIPPAPVKQQQQQQLPPPPSPLPMQTMQYRQDPATPVAKMDQPTTGVHVMPLNLSAKPKPAVITVPVSSLSNCSVPATPSTSAGSSGSSKAAPPAGQINNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADKLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVASRLNAAQTPARTSTVTAPTATAPATTLAAAPAPAPAPAPAPVPSSLVPAPQLPLEGLRFVDAPLPSPGPLLGKTPLVDYAQQNAPRKAQDSVVITKMHEDRQFASLDIEAPHAKRVKSSDLAASASSSSQGFSFPFTNHNTNSLPEPQPVKEERLRRFTSSGGTMIPISECPDLENSPKMIRTPLLSGGSFQEVSAKVNDAGSSKERKRLALISGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSAGGEKSTPVTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPVPSGRGRSPNRKQPSPLLMGAAVAGELKALSPFGGVQNLPSEFSRQPPTPAQRQALQWNSKESTHKKAPFNFLRMADNVKATTEPEVRHFNLDNVIAAKQSEASPLTPLHVETPNGSAAEEASQSTSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHMLSMYSVWQVCEENQPHPLGFKLKKVMSLYDSRQRMLGNGSSTAMAGSGKLSYNVVSSQQTVCSTSTLASASSSAFYQNQLKTSPSAVTVSVLSEANVAAKANEEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQLLQDTPLPAASPANSIGSSGSLPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSAASEESAPMDLTKPRGSMSAAVSPSPVPVQPPVHDLPKSQAQQMHDVIFGSSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVLLQTYIKEQALHHAKRKQSQFSGSYLINTLFSTTSTVMSSSSSSSGSGNLLTTSSRPIMTINEVPSIEVHEVKTPEAVDLPAIPPVVAQPTPTPTLTPTPTPTPIPVKLVQEESEESDQEKPMVEPHNANLPAAVQQKDANDFSGVLGHPQSGGAATVVTSTPAPVAVSSNTNTTQPTQRTVIVGEDGFKNSTPSSKSSDLQPHVSYARAVPVPAPIASDVRPTCSICAKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDPANPASQDSASEDGFSAAVAIASAIASLDNDSAGNTPKRASSMSEDESVANGLNHNLKRRLPGSFSSTGEESDNPTEGNGGEKRARSSQDLPVAVPVAASAAAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594759;
90% Identity: iTF_00594759;
80% Identity: -