Dnik001495.1
Basic Information
- Insect
- Drosophila nikananu
- Gene Symbol
- -
- Assembly
- GCA_008042635.1
- Location
- VNJV01006146.1:11155-16990[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0021 0.24 12.4 0.8 1 23 1317 1340 1317 1340 0.97 2 13 6.4 7.2e+02 1.4 0.2 1 23 1492 1514 1492 1514 0.91 3 13 0.00014 0.016 16.0 2.7 2 23 1517 1538 1517 1538 0.97 4 13 5.5e-05 0.0062 17.3 0.2 3 23 1546 1566 1544 1566 0.98 5 13 4.6e-07 5.2e-05 23.9 4.1 2 23 1573 1594 1572 1594 0.97 6 13 4.3 4.9e+02 1.9 0.4 5 23 1607 1625 1605 1625 0.96 7 13 1.1 1.2e+02 3.8 5.4 3 23 1632 1653 1630 1653 0.93 8 13 0.11 13 6.9 0.2 2 23 1664 1684 1663 1684 0.96 9 13 4.4e-05 0.0049 17.7 0.4 1 19 1690 1708 1690 1712 0.95 10 13 2.8e-05 0.0031 18.3 0.4 1 23 1720 1742 1720 1742 0.98 11 13 8.2e-05 0.0093 16.8 7.6 1 23 1748 1770 1748 1771 0.96 12 13 0.00017 0.02 15.8 6.5 1 23 1776 1798 1776 1798 0.98 13 13 0.0021 0.24 12.4 6.1 1 23 1804 1826 1804 1827 0.96
Sequence Information
- Coding Sequence
- ATGGTGGACAACAGCGTTCAGTGCCCCGTGTGCACCCTGTACCTGCATGCGGGAATGAATCTCTCCGATCACCTGGAGACTCATCCCAAAGAGCAGGTGATCAAGGCGCTGGTCCAGATGACGATTGTCGGAAGCGGTGGCAACAACAGCATGGGCAGTGCTCTGGCGGCCGCTATGATGTCAGGAGGCtcgggagctggagctgggggcggaggcggcggtgggTCTGATGGCGGAGAAGCCAGCATGGCAGATGATAAGACCGCATTCACATTGTCATCTCCTTGTGGCGATGTCAAACCAGTTGTGGCTAGCAGCCCGCCAGCGATGTCCAAAACCATATCAGCTGCAATACCCGTAGTGCCGCCAGCACCGCCGTTGCCGCCGCTCTCTTCCGCCAACGCTACACCCTCTTGCACATCCCCTTGTGCAAGTAgtagcaccagcagcagcagcaatttgAGCAATCCACCGATGAAAGCACTGAATTGCGCACCGCCCACGACTGAGGCGCGAGCCAACACATCCGCACATCCCACCATAAGCAGCGTGTCCACACTGTACCAGTCGTCGCTGGTCACTCCGGATTATCGCTTCaatcaccagcagcaacagcagcagcagtcgggCTTTGGGCGTGGTGTTGCTGGCACCAACGCAGCCACGCTGGTAATACCACAGGTTGCGCAGCAGCACTTCCTCACCAGccatcagcagcagggccACTTCacccatcagcagcagcagcagtcgcccCTAAAGTTTACCTACGCCACCGctttgccgccgccaccgccgctgcaGCTCTTTACGCAGCAACAGAATCAGCCGCCGACAGCCTCAACGCAGTCGCTGCAGCAACCTCACCAGAAACCACCTCCCGCCTACGGAGCCGCCATCAGTCAAATACGATCTCAGCACAACCAAATcaagcagcagccacatcaacagcagctgcagcagcagtcacAGCCACCCCACATGACCGGGCAGCACAACCTAACCCTGGCACCACCgacaccaacaacagcagcaggagtagCTCCTGCGATATCAACTGCAGCTGAGAAGCAGCCCAGTAAAGCGCATGGGGAGGTATTCCTGAATCCCcctccaccaccgccgccacaGCCACAGGCAACGACGGCATCGATCCACAGTATGGGGCAACATCAGCAGAATCATCAGGGTCACCCACAGTCTCATGTCCATCCGCATTCGCAACAGCAGACTCACCACCAGCAGTTGGCCCTATCACCCTCCTCAagattgcagcagcagcagtcactCAGCTTGCAGTCTTACGGTCCGGGTATGAGCAGCAGCTGTAGTTCCAGTTCTGCTTCCAACTCTGGATCCGTCGCTGGCAGTCGGGGCAATCGGCAAACCAACTCACCCTTTGGGGCACTGCTCAACGCAGCCGCGGCTGTGGCCTGCAACACGACGCCGGCCTCGACCAACGCCTGCTCGTCGGTTCTGCGCTTCGCGGAATCACCGGTGGCCCACTATCTGGAGAGGGAGAACGGCGACTTCATTGTCCAGGAGACGCCCAAGCATATTGTGGAGTGTGTGGAGAAGGAGGACGGTGAGTTCTCTGTGATCGAGCGCATTTACCAATCCCCGCCGAGTGTCTTGCACATACACGATGACGATGAGGACGAAGAGGatgaagaagaggaggaggaggacgacaaCGACCACGAAGCTCAGccagaggaggaggtggacgGGGACGATGAGCGGGAGGAGAATAGCCGCAGTCTCAGCCGCAGCCGGAATATGAACAAGACAACGAAAAAATCGCGGAAGGCCAAGCCCAAGCGAAGCTCCAAGCGCGTCTCGCACTTGGATGAGGAATTTATGAGCATTAGCAGTGGCTGCGAAAGTGAGACGGAAACGGAGCGCAAGCCTGAGTCGACGTCAACCGTTCCACCGCCGCTTTGCACAGGTCCCTCTACCagctctgccgctgctgcagccgccgccggAACGTCCAGCAATCTGGATACTCATTCCAATTCGGCCTCCAATTCCGCCTCGAACTCCACATCCACCACGACCAAATCCAAAAAGAATCGGATCACGGTGCTCAGCGATGTGCCGCTCAACATGAATGAGTACCTCGATCTAATGGGCAACATTGTGGCCTCCAGTCGCATTGGGGCAGGACGCCCCTTTGCCGCTGTGGTTCCCATTCCCCTCGTCAAGGTGGAGAAGGAGGAGCCCTTGGACGAGTACGACGACAGCGAGGCGCCGCAGCAGGAAGAGAAGAAGCCCAGCTTGGAGCACGGCACCACCAGCGTCATTCGCATGGCCAGCACAGTGGCTGTCACGACAACGACGCAGGTGACTGAAGAGGAATCCGTCGAGGATCTCAACGAGCCACCGCTCATGAAGGTCGAGGTGGAACCCAACACGATGTTGCTACCGCAGCGCTTCTCCACTCCCGCCCAGAGCCGCGGGCCCAAGAAATTAGTCATCAAACCAAAGGCAACAGCATCCGCACCAGCGACGGCgacgacaacaaaaaagacTGACACCTCTCcatcttcctcctcctccagcaacAACACATCCATATCAAAAGATTTGGGGCAGGTTCAGGTTAAAAGTGAGACTGTGGAGGCTCCAGcggcaaacagcagcagcagcagcattctGGAGAAGCACCTAACCACCAACCGCAACCAGATCCAGCAGCACCATTCGGCGgtcaatgatgatgatgcccgGGTGTTGCTGGAGTTTGCCAACTCCAAGCAACCGCCACCGGTGGCAGCGTCCAGTACCACGTTCGTGGTGAATGCCAGTACGGGATTCCCATCGGCAGGGTCCGTtttcgccagcagcagcagctctaaGCCGGCCTCAAAGCCTGGCGAGGAATACATTCTGCCGGACAACACCAACCTGGAGGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACGCCTCCTCAACGGTCCAGGTGCAGGCAGCGCTGCAGCCGCCGGACTTTAACTTCCTTTACCAGCAGACCACCAACACCGCCACCGCGGCTACCTATTCCTTTAATGCCTTCTCcaggcagcaccagcagcagcaacaacacggTGTAAGCGATGCCACCAATGCGGCCACCTTGGCCTCCTCTTCCAGCAATTCCATGGACCACGACTCGATGAATGCTTCCTTCCGTGTGGCCAAGACACAGTCGCTGCAGTGGTAccagcaggaacaggagaACGGTCCACAGATCCAGGCAGAAAGAGCAGGGGCCTCGGGGGTGTCCTCCAACCATAGCCACACGGATGTAGTCAGCCACCAGCCCACCAACTTCAATGCCGCCCTGGCGGCCGTCGATTGCTGCAGCGTTGCAGCAACGCTGGACGAGGAAGCCAAGTATCTGGACTTGGACACATGCAAGCGGGAGCAgttaagcagcagcagcaacctgcCCTCAGTCTCCGCCTCCACGTCCACCACCTCATCCTCGTTCGCCGGTGCCGGCACGGAGAGCAGTTTGGTCGGGGGCCTCAACATTCGCACGGATGAAAAGATGCCCGCCAAGGGTGAGATCTCCGAGCAGGAGAGCAACTGTGACATAGAAAACTCGTGGAGTGAGTCGGTTTATGGGGACATTTCGCAGCGGTACTTCAGGAACCAGTTCTCCGGAGGCTACAACCCTGAATGGCGACAGGACTACTACCCGGCTCAGGATCTCAGCGGCGGACAGGAGAGGGAGCAAAAGCGCTTCGACTTTAACGCGGTTGATGATGAGGCCTCGTCCAGCTCTAGGAAGAGCCAGCTAACGGATATCGTCCCAAGTGTGGCCACCTCCTCCACTTCCACGTCATCGGCTTTGCTGGCGGGTCCACCAATAGCTTCGACGTCAAGGGCTGCCGCTGAAGCGGcagcggaggcggcggctTCTCTCGCCCAGCGAAAAACACATCGCCGTAAGCTTTATAAGTGCCCCCATTGCGATACCATCTACGAGAAGCTCAAGGAGCGGAACGCCCACATGATTAGCGACCATAACTATGTGCGTCAAAATCGAAGACTCATCTGTACCCAGCAGGTCGGTCAACCGATGCTGCCCCAGCAGCATGcccagttgctgctgcaaacGGACGAGGCTGTGCATGAGGACTCAAAGGATGGCATTGTGAAGATCAAGCAGGAGCAGTGTTCGGATAAACCGGAAGTCGAGCAATTGGACCACGCCAATTCTGCTGAGCTGCTGTCGGATGTCAAGGATTCAGAGCTTCTGGGCATCGGCGGCGAGGGCGATGCGGACTTAGACGGCGATATTAAGCCACCTAGCCAGCTATTTGATAAGTCGCCCAcactgccgccgctggccaTGACAACGCCGGCAGCAAAGCTGGCGGCACTTTATCGCATGCTTATCGCCTACAATGAATCAAAACTGGGCCAGGAGCGCAACAACCTCAGCGAACTGGAGCAGAAGGCCATGGAGAAGTCCATCTTTCTTTGCTACGTCTGCCGCACCGACTTTCCCTCCGTTAAGCTTTACGACGCCCATCTTACCGAGCACCCGGCCGAGTGTTTTACCTGCGGCAAGAAGTTCTACCGCTGGAAAAACTTCTCCCTGCACCTGAAGCGGCATCTGGGCTGGAAGGAGTTCGGCTGTTACGTGTGCGACAAGAAGTTCGTGGTACGGAGCGCCCTCGTCGAGCACATGCGGATGCACACCGGCCAGACACCGCTCAAGTGCAAGATATGCGGGAAAAAATTCAAGCGCTACTCGAATCTGACGCAGCACCGCAAGCGCCACACCAAGGTGATGGTGCGGAAGAAGGAGTACGTGTGCCACTGTGGCGAGGTTCTGCCCTCAAAGGCGCGCTTCCTCTGGCACAAGGAGACGCACGACTTGAAGCCGAAATGCTGCCCTTATTGCTGCGACAGATTTGTGCACGCCAACTCCCTGCGCCGCCACATACGTCTGGCACACTCGGACAAATTTGACTACGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTCGCCAAGACATCGATCAAAGCCCACATGGCGACGCACTCGACGGAGCCGCAGTACGACTGCGCCATCTGCAACAAGAGCTTCTCCACAAAATGGAATCTCAAGATCCACTCGTGGGTCCACGCCAATCGGACGGCCAAGCCCTTTAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAACCACATCAACGCGCACAAGCAGATCAAGCCGTACACGTGCGAGTACTGCGGTTGCAAGTTCATCCGCAAGTACAACTACATGCGGCATCGTCGCGAGCACCACGGCACCAAGAAGTTCACCTGCGACCAGTGCGACAAGTCCTTCCATCGGCACTACTATCTGATCGAGCACCGGCGCATGCATACCGGTGAGCGACCGTTCACCTGCACCATTTGCGGCAAGAGCTCCACCACCAAGACCAACCATAACAAGCATCTGAAGATCCATCACTCGCGCGACCCCTTCACCGTGGAGGTCTAA
- Protein Sequence
- MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGSGGNNSMGSALAAAMMSGGSGAGAGGGGGGGSDGGEASMADDKTAFTLSSPCGDVKPVVASSPPAMSKTISAAIPVVPPAPPLPPLSSANATPSCTSPCASSSTSSSSNLSNPPMKALNCAPPTTEARANTSAHPTISSVSTLYQSSLVTPDYRFNHQQQQQQQSGFGRGVAGTNAATLVIPQVAQQHFLTSHQQQGHFTHQQQQQSPLKFTYATALPPPPPLQLFTQQQNQPPTASTQSLQQPHQKPPPAYGAAISQIRSQHNQIKQQPHQQQLQQQSQPPHMTGQHNLTLAPPTPTTAAGVAPAISTAAEKQPSKAHGEVFLNPPPPPPPQPQATTASIHSMGQHQQNHQGHPQSHVHPHSQQQTHHQQLALSPSSRLQQQQSLSLQSYGPGMSSSCSSSSASNSGSVAGSRGNRQTNSPFGALLNAAAAVACNTTPASTNACSSVLRFAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDEEDEEEEEEDDNDHEAQPEEEVDGDDEREENSRSLSRSRNMNKTTKKSRKAKPKRSSKRVSHLDEEFMSISSGCESETETERKPESTSTVPPPLCTGPSTSSAAAAAAAGTSSNLDTHSNSASNSASNSTSTTTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGAGRPFAAVVPIPLVKVEKEEPLDEYDDSEAPQQEEKKPSLEHGTTSVIRMASTVAVTTTTQVTEEESVEDLNEPPLMKVEVEPNTMLLPQRFSTPAQSRGPKKLVIKPKATASAPATATTTKKTDTSPSSSSSSNNTSISKDLGQVQVKSETVEAPAANSSSSSILEKHLTTNRNQIQQHHSAVNDDDARVLLEFANSKQPPPVAASSTTFVVNASTGFPSAGSVFASSSSSKPASKPGEEYILPDNTNLEVDEIVISSSSSYASSTVQVQAALQPPDFNFLYQQTTNTATAATYSFNAFSRQHQQQQQHGVSDATNAATLASSSSNSMDHDSMNASFRVAKTQSLQWYQQEQENGPQIQAERAGASGVSSNHSHTDVVSHQPTNFNAALAAVDCCSVAATLDEEAKYLDLDTCKREQLSSSSNLPSVSASTSTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNQFSGGYNPEWRQDYYPAQDLSGGQEREQKRFDFNAVDDEASSSSRKSQLTDIVPSVATSSTSTSSALLAGPPIASTSRAAAEAAAEAAASLAQRKTHRRKLYKCPHCDTIYEKLKERNAHMISDHNYVRQNRRLICTQQVGQPMLPQQHAQLLLQTDEAVHEDSKDGIVKIKQEQCSDKPEVEQLDHANSAELLSDVKDSELLGIGGEGDADLDGDIKPPSQLFDKSPTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKVMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00491690;
- 90% Identity
- iTF_00594723; iTF_00491690; iTF_00594001; iTF_00524572;
- 80% Identity
- -