Dnik008830.1
Basic Information
- Insect
- Drosophila nikananu
- Gene Symbol
- -
- Assembly
- GCA_008042635.1
- Location
- VNJV01003408.1:10106-11458[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 6.6e-05 0.0074 17.1 1.2 2 23 168 190 167 190 0.96 2 9 0.00032 0.036 15.0 0.2 1 23 197 220 197 220 0.97 3 9 0.006 0.67 10.9 0.7 1 23 227 252 227 252 0.93 4 9 9e-07 0.0001 23.0 0.9 1 23 264 287 264 287 0.97 5 9 0.0061 0.69 10.9 5.7 1 23 304 327 304 327 0.94 6 9 0.002 0.23 12.4 1.3 1 23 342 364 342 364 0.97 7 9 3.2e-06 0.00036 21.2 0.2 2 23 370 392 369 392 0.94 8 9 0.00043 0.049 14.5 3.4 1 23 398 420 398 420 0.95 9 9 5.8e-06 0.00065 20.4 2.5 1 23 426 448 426 448 0.98
Sequence Information
- Coding Sequence
- ATGCTGCGGAATCTAACCCGGGAAACCGCCAGGGAGCACTGCCGCACCTGTCTGCTCAAGCTAGACTTAGAGCGGGGGGCAGACAGTTTCCAATCAGACGCCCTCCCAATCAGCCCGGAGCTGCAACAGTTGCTCGATATAAATCTCTTGTTGGATCGGAAGCCAGAGAACGCAGCGGAGAAAGAGCAGTCGTGGTGGCCCCGAGAACTGTGCCCGGAATGCCTCGAGCTAATCCGTAACTTTGAGAGGTTCCGCACCAGAGCGGGAGAATGCCGTCAAAGGTTGCTGCAAGTGctcaagaaggaggaggaggaggatcaaGATCAGGAGCCGAATTTCGAGGTGGTTTACCAGGACCTAGACGGTCTAAGCCACAATCAGGAGTCGCTGCACAGTCTGGAGCCACCGGAGCCCGATCCCGACCCCGATCCCATAGATGAGCCAACCGCACAGCCCGTGAAATGCGGAGAAAAGGCCGCGAGAAGTGCGAGGAACAGCCTCAAGTGCCCGGTGTGCCGGCACAGCTTTGCCCACCAAATCACCTTGGCAGCCCACGTCCGGAAGGTGCACGAGGGCAGCAAGCGACCCTTTCAGTGCGATCAGTGTGAAAAGGCCTACAGCTTCATGGGCGGCCTCTACACGCACATTCGAGAGGTGCACACGCCGCTGGAGCGACGGCATCCCTGCGACCAGCCGGGCTGCGAGCGCGTCTACACCAGCCGCATAGCCATGCAGAAGCACAAGCGGCTGAAGCACAGTCCGCGGGAGCGAGACAGCGTCCCGCGCAAGTTCATCTGCGAGCAGTGCGGCGCCAGCTTCAATCAATCGGCCAATCTGAAGTACCATCGTCGCACGAAGCATCCGACGGAGGACGAGCTGGCCGCCAAGGAGGGCGGCAGCGGGGAGCGCCACTACTGCGACATCTGTCAGAAGGAGTTTCACTCGCGCTACACACTACGCTATCACACGCTGCAGCAGCATGCCACCGCTAACGAGGATGGGAGCGGCCAGGACGTGCTGCCGCACGAGTGCCAGGTGTGCGGGCGCCGGATGGCCAAGAAGTTCATGCTGCTACAGCACATGCTGATGCACTCCAGCGACAAGCTGCCCTGCGAGCACTGCGGTCGACGTTTCGCCCGACGCTTCGAACTGGAAGCCCACGTCCGGGCGGTTCACCTCAAGCTCAAGCCCTTCGCTTGCCGCCACTGTCCGGAGAGCTTTGCCTCCCGCAAGACGCTGCGGCACCACGAGTACATCCACACGGGCGAAAAGCCGTATGTGTGCGGCACCTGCGGCCAGGCCTTCCGGCAGCAGACGTGCCTCAAAAATCACCGCAAGGTGCACGACAAGTAG
- Protein Sequence
- MLRNLTRETAREHCRTCLLKLDLERGADSFQSDALPISPELQQLLDINLLLDRKPENAAEKEQSWWPRELCPECLELIRNFERFRTRAGECRQRLLQVLKKEEEEDQDQEPNFEVVYQDLDGLSHNQESLHSLEPPEPDPDPDPIDEPTAQPVKCGEKAARSARNSLKCPVCRHSFAHQITLAAHVRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHTPLERRHPCDQPGCERVYTSRIAMQKHKRLKHSPRERDSVPRKFICEQCGASFNQSANLKYHRRTKHPTEDELAAKEGGSGERHYCDICQKEFHSRYTLRYHTLQQHATANEDGSGQDVLPHECQVCGRRMAKKFMLLQHMLMHSSDKLPCEHCGRRFARRFELEAHVRAVHLKLKPFACRHCPESFASRKTLRHHEYIHTGEKPYVCGTCGQAFRQQTCLKNHRKVHDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00488841;
- 90% Identity
- iTF_00524584;
- 80% Identity
- -