Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01000566.1:22759-38408[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0054 0.65 11.1 2.6 1 23 923 945 923 946 0.95

2 8 0.35 42 5.4 1.0 1 23 951 974 951 974 0.96

3 8 0.00051 0.061 14.4 0.4 1 23 1179 1202 1179 1202 0.95

4 8 0.002 0.24 12.5 0.8 2 23 1211 1232 1210 1232 0.97

5 8 0.016 1.9 9.7 0.2 1 23 1239 1262 1239 1262 0.96

6 8 1.2e-05 0.0015 19.4 1.4 1 23 1268 1290 1268 1290 0.97

7 8 2.2e-05 0.0026 18.7 0.4 1 23 1295 1317 1295 1317 0.99

8 8 1.5e-05 0.0018 19.2 2.7 1 23 1323 1345 1323 1345 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0054	0.65	11.1	2.6	1	23	923	945	923	946	0.95
2	8	0.35	42	5.4	1.0	1	23	951	974	951	974	0.96
3	8	0.00051	0.061	14.4	0.4	1	23	1179	1202	1179	1202	0.95
4	8	0.002	0.24	12.5	0.8	2	23	1211	1232	1210	1232	0.97
5	8	0.016	1.9	9.7	0.2	1	23	1239	1262	1239	1262	0.96
6	8	1.2e-05	0.0015	19.4	1.4	1	23	1268	1290	1268	1290	0.97
7	8	2.2e-05	0.0026	18.7	0.4	1	23	1295	1317	1295	1317	0.99
8	8	1.5e-05	0.0018	19.2	2.7	1	23	1323	1345	1323	1345	0.99

Sequence Information

Coding Sequence: atggcaacaacaaacccAAACACCAGCAGCTGGTGCATTTCCCGCAACGATGGCCTGCCCCAGGAGATTTGTCGACAGTGCAAGGCGCAGTTCATCATGGTGGCCAAGTTCCGGCGGCGTTGCGTGCGTGTTCAACAGCGTTTGCAGAACTACGCCCACAACATAGCCGTGCGCAAGGCACAGCCAGCGGCGGTGGAGCCACGGCAGCCCAGTGAATGCCCGGCCGAGGATTATCAGCATCTACCGGAGCGCAAGCGTCACCTGGTGCAGAACACACAGACGGAACCGGCACCGGAACTGGAGACGGGGCCAAAACAAGTCAAGACTGAGGTGCCGACACCACCGAAAATGCGACGCCTACAGCTGCGTGTGCGCAAGATGCGCATTGCCTCCATGCCAGCCAACAGGATTGAGACTGAGATCGAGGACTTGGAGCATCGTCCGACGATGCGCAGCGCCTCACAGCAGAACGAGTTGAGAGAGCGGACGCCGCAGCGGAACACCTGGAGGACGAAGGCGGCACGCAAACAGCTCTCCGAAACGTGGGCCAACTGCTCGACGGAGGAGCACCTGGCACAGAACTCACCACCAGCTCAGAGTTCGGAAACGGAAACGAGTGCAGGTCAAACTTCGCCGGAGCAGCTCAGCGATTTGTCCGTAAATCCCTGTCGCGGCTTTGAAAGCGAtggctgctcctcctccacctcctcctccacctccaATTTAAATTCGACCTGCAACTCCCCctcagcagaagcagcagcgacgcccaAACCAAATGTTAAACTCGAGTTTCCACCAAAGCGAGCTAGCAGCAAAAAACAGTTCGTGGTACTGCGACGTTTCCGTGCCAGCTCCGTGCCGCTCAAGCGGCCGAGACGCGTGCTCCAGCCGCGGGAGAAACAGAGAAGCAACAAGCCAAAGAAAGCGCGCACAGCTGAGGCAGTGGAGCAGCTGATAAACAGCTCGTCGGACGAGACGCCGCCCATCAGCAGCCCGGAAATTACCGCAGCGGAGCAGGAGGCCAAACTAGCCGAGCAGGAGGTCTCCCAGATTGAGCAAATGGAACTCAACGTTAAGGAGCAATCTTCGCCAGAATCAATTGACACTCAGGCGAATCTGGGTTCAATGGGAATGGAAAGCATATCAATAGAAGAAGCAATAAACGATGCAAAGGGAATGGAGGAGTACGAGCTAGCCATCACAAATAGAACATCAGATGCCAGCGAGGAGCTAATCTCCTCCAGCATGGAGCACAGGCAATCCCTGACGCCCGAAGTGCCGGCGGCTGAATGTGAAGTGGAGGTGGTGGGCGTGACAAATGAAGAGCAGGCGGAGAAGCTGACTGAAGAGTTGGCCGAGTTGCAGTCCGAGGAGTCCCAATCGGAGCTTCTAGTGAGCATACCTCTAGATGTGCTCGGCGAGGAGCTGCAGCGGAAGCTGTGCATAGAGTCACAGCCCGAAACGCCACTGGAGAACCAGCCCAAGGAGCCGACGGAGGCGGACGATGTGAACAACAATGCGAATGGTGAGAATTTTTGCCAGAGTGCCGCAGCAGATAGCTTCAATGCTGCTGCGGCACTCGAGACGCTACCAATTGAAGCAGAACCACCCAATGGAGGAGGGCCGTCGACGCCGAGCCACGACGACGACATGGACTCCCTGGAGCGGCTGGCCGCGTTGCAATCGCCCCAACATGAACGCAGCGAGGAACTGCAGCCGTTGCGGGCGCCGATCAATGCCAGCTCCATGGACTTTTTGGCCGAGTTCGAGAAGCACTGCGAGAAGACGCTCAAGCTGAAGACGACGGCGACCcaggaaatggaaatggaaatagcAACGGAAACAGAAgcggaactggaactggagcccaagcagcaacagcagcagcagcagctgccggtCGAGATAAACGATGTGGAGAGCACACTGCACGGCATACTCAACGAGATGGAGGACCAGCATATTTATACGCCTATCGATGAGTTTTTCACGCCCGCGGATTACGAACCGCCAGCGGAggtgccgcagcagcagcagcatcagcagcagcaacgagagcagcagcaacagcagcaggtgagGGAGGGGAACCTGTTCGACAGCAGCGATTTTAGCAATGAGCTGATTGGCTTCCAGAACGATGTGCCCTGCTTTCAAAATATCGCGACGTCTCAAGAGTCCAGAGAGAGTCTGCTGGAGCTGACGCAGTTGTTAAACGAGATCCAGCCGgctcagcagcaacagcagcaacagttgcagcagcatcagttgcagcagcaacaattgcagcagcaacagttgcaacagccacaactgcagcagccgcaattGCAGGAGGAAACTGTCAGCTATGAGGCACTGTATCAGACACCTCTTCCGCCCGTCACCACGCtgagcagcaacaagttgCAGCTGATACAGATGCAACCGCAGGAGACGCTGTGGCAGACGCAGCCAGCGGcccagcaaacaacaacaacacagctgCAATGGTCTGCGGTGGGCGGACTGGAGGCGATCAAGACGACAACGGCGACGCCGCTGGACAATCTGGAGGGCAATGGAACGACCACGTACTACATCAATGCCAGCGATCTTTATCCGCAAGCGGGCGAAATATTAGCCgctgtgccgccgccgccgccgcccgcccGCGGCCGTCCGCCCATGCTCAAGTGCCGCTTCTGCCAGAATGGGCCGCGCTTCTCGAGCAGCCTCGAATACAGTCGCCACATCATCGAGCTGCATCCGGCAATAGCGCCCTTCAACTGTCCGCACTGCCCGCTGGCTTTCTCCGGTCGGAGCAAGCGCAGCCAGCACATCCTTAGCCACCACTTGGTGCAGCAGTTCCACTGTGGCCAGTGCTCCCAAATGCTGCCCTCGCAGCGGGCACTCGACCTGCATCTGCAGCGATTCCACATGCCACTGCCCACGGAGACGACGAAAGGGACGGGGACGGCGACGGGTTCGGGTTCGGCGGGCGTTCGACTGGAGGAGGTGAAGCTGCaagtggccaacaacaacaatgagcagccaaaacagcagcagcaacacgtgCTGCATCAGCAAACATCTCCACATATGCCTGCTTTGGAAACAAGCCCGTCTCAGCCACGCAGAACGCGCATACTCTGCTGCCCGGACTGTGAGGACTGCTCGTCGGCGAGTGGACACCAGCATGTCGAGGAGCTCAGCAATTTGCAGACGCCGCCGACGGTGCTGACGCCGCCATCGACAATTGCATCGCTGCCgtcgccgcagccgccgccgctgcacaTAACGCTGCCCTCGCCGGAGCAATCGGAGCCGGACTCGACGACGGCCACGTTGCGGCAGTTCCGCAAACGCTGCATAGCCAATTGCACGAcggtagcagcaacagcagcaacaacagcaacaacaacaacagcagctactgctgctgcagcaacaacgctGCTAACAGCCGCCTCGCCGTCGCCGTCCTCGTCACCATCCTCCTCGACGATGGAAACAAGCAGCACAGTCCAGATGGGCAAACTGCGGAGCAGCCATCCGTGCGTCGTCTGCGAGAAGCGCTTCACCAACATCATTGCGCTACggaagcatcagcagctggcgcacGATTCGCAGACCACGATGCCCTGGGTGTGCTCGATCTGTAAGCGGGGCTATCGGAAGCGGACGGACATGGACAATCACATGAAGTCGCACGAGCCGAAGGGACGGCCGTATGAGTGCAACGAGTGTTGGGTGCGTTTTCCCGAATTGAAACAGTTGGCGATGCACAAGTTCACCGTCCATGAGCTGATCAAGCCGCACACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAGCGCGGCTTCGAGTGCGATGAATGCGAAGAGGCATTCGCATATATCAAAGATTTGCGCAAACATCGGCGCACCCACAACACCGAACTATTTTACAAATGCGATTATTGTCCACGCACGTTTCCACATTTTACGAGTTATAATGCGCATATAAATACCCACCTACCGCTGGGCGTGTTCATCAAAGACAAGATGCACAGTAGCGTGAGCAGCAGATCCGATAATCCATTGACGCCGGCAACAATCGAGGACTCCTCGCTGCCATTGACGCCGCTCAGCAACTGCAATgggaacagcggcagcggggAGGATTGTCCCAGCTCCGTGGAAATGATGGTAGAGAGCAGTGGAGCGTTGGCGCCATCGTTGGATATGATTGTCGATACGCCGTAA
Protein Sequence: MATTNPNTSSWCISRNDGLPQEICRQCKAQFIMVAKFRRRCVRVQQRLQNYAHNIAVRKAQPAAVEPRQPSECPAEDYQHLPERKRHLVQNTQTEPAPELETGPKQVKTEVPTPPKMRRLQLRVRKMRIASMPANRIETEIEDLEHRPTMRSASQQNELRERTPQRNTWRTKAARKQLSETWANCSTEEHLAQNSPPAQSSETETSAGQTSPEQLSDLSVNPCRGFESDGCSSSTSSSTSNLNSTCNSPSAEAAATPKPNVKLEFPPKRASSKKQFVVLRRFRASSVPLKRPRRVLQPREKQRSNKPKKARTAEAVEQLINSSSDETPPISSPEITAAEQEAKLAEQEVSQIEQMELNVKEQSSPESIDTQANLGSMGMESISIEEAINDAKGMEEYELAITNRTSDASEELISSSMEHRQSLTPEVPAAECEVEVVGVTNEEQAEKLTEELAELQSEESQSELLVSIPLDVLGEELQRKLCIESQPETPLENQPKEPTEADDVNNNANGENFCQSAAADSFNAAAALETLPIEAEPPNGGGPSTPSHDDDMDSLERLAALQSPQHERSEELQPLRAPINASSMDFLAEFEKHCEKTLKLKTTATQEMEMEIATETEAELELEPKQQQQQQQLPVEINDVESTLHGILNEMEDQHIYTPIDEFFTPADYEPPAEVPQQQQHQQQQREQQQQQQVREGNLFDSSDFSNELIGFQNDVPCFQNIATSQESRESLLELTQLLNEIQPAQQQQQQQLQQHQLQQQQLQQQQLQQPQLQQPQLQEETVSYEALYQTPLPPVTTLSSNKLQLIQMQPQETLWQTQPAAQQTTTTQLQWSAVGGLEAIKTTTATPLDNLEGNGTTTYYINASDLYPQAGEILAAVPPPPPPARGRPPMLKCRFCQNGPRFSSSLEYSRHIIELHPAIAPFNCPHCPLAFSGRSKRSQHILSHHLVQQFHCGQCSQMLPSQRALDLHLQRFHMPLPTETTKGTGTATGSGSAGVRLEEVKLQVANNNNEQPKQQQQHVLHQQTSPHMPALETSPSQPRRTRILCCPDCEDCSSASGHQHVEELSNLQTPPTVLTPPSTIASLPSPQPPPLHITLPSPEQSEPDSTTATLRQFRKRCIANCTTVAATAATTATTTTAATAAAATTLLTAASPSPSSSPSSSTMETSSTVQMGKLRSSHPCVVCEKRFTNIIALRKHQQLAHDSQTTMPWVCSICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPELKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFECDECEEAFAYIKDLRKHRRTHNTELFYKCDYCPRTFPHFTSYNAHINTHLPLGVFIKDKMHSSVSSRSDNPLTPATIEDSSLPLTPLSNCNGNSGSGEDCPSSVEMMVESSGALAPSLDMIVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567811; iTF_00547593;
90% Identity: -
80% Identity: -