Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: BCL11A
Assembly: GCA_004149445.1
Location: SCDR01000096.1:213403-231804[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.022 2.7 9.2 2.4 1 23 301 324 301 324 0.95

2 6 2.2e-06 0.00027 21.8 1.0 1 23 771 793 771 793 0.97

3 6 0.01 1.2 10.2 4.7 1 23 799 821 799 821 0.99

4 6 9.6e-07 0.00012 22.9 3.2 2 23 1094 1115 1093 1115 0.97

5 6 1.3e-05 0.0015 19.4 3.3 1 23 1121 1143 1121 1143 0.99

6 6 2.3e-05 0.0028 18.6 0.4 1 22 1151 1172 1151 1172 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.022	2.7	9.2	2.4	1	23	301	324	301	324	0.95
2	6	2.2e-06	0.00027	21.8	1.0	1	23	771	793	771	793	0.97
3	6	0.01	1.2	10.2	4.7	1	23	799	821	799	821	0.99
4	6	9.6e-07	0.00012	22.9	3.2	2	23	1094	1115	1093	1115	0.97
5	6	1.3e-05	0.0015	19.4	3.3	1	23	1121	1143	1121	1143	0.99
6	6	2.3e-05	0.0028	18.6	0.4	1	22	1151	1172	1151	1172	0.97

Sequence Information

Coding Sequence: atgtacaataaaaTACTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCACTCCGACTCCACAGAGAACGATGCGGTCGCCGCGCAGGACATCCTCACGTGCGGCGCTTGCCAGAAGACCTTCGCGCTGTCGGACATTGTCCGCTTCATTCAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCACCACCCAGGCGCCCAGCATGGATCGCGATGCCGATGAGGGTCGGCCGCTGAGCCTGGTAAATCGCCGTCCCTCGATATCAGCGCCGATCACAGGCCGCAAATCGGCACCGGTTGCCGTGGCGCCACCGAACgccgcagcggctgcggcggcagcggcaacggcagcggcaacggcagcggctgccGCGGCAGCTGCCGCCAGCGCTGCGAGCGGctcacgcatacacacaccgCCGCCCAGTCCAGCGGACCTGCTCGCCGACGGCGCCAGCAGCACGCCCAAGCGCCTCGTCGATGAGAACGACAATACGACGCCCAAGGCGGACGGAGAGCCGCTGACCACGGCACCGCTGGAGGCCTCCAGCGGCAGCGCGCACAgccccagccacgcccactcggAGCAGACACAGCCGCAGCTGGCGTCGcggccgtcgccgtcgccggaCTGTGCGCTGAACGATGACAAGCCAAAGGTGAAACAGGAGCCGTACGCCGACGACGACCTGCCccaggacaacaacaacgaggacGAACAGCCcgaccagcagctgctgaccccaaccccaaccgcAAATCAAACCGCAACCGAGACACAGCAGCCGCCCGCGGCGGACGAGTGCCAACAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAGGCGAACACGGTGCACACAGAGCCCAGCAACTACACGTGCTCCACCTGCAAGACCCGCTACACCTCCGCGTGGCGCCTCATTCAGCACGTGCAGCATTCGCACGGCGTCAAGATCTACGTGGAGGCGGGCGGCGGCGCCACTTTGACCGTGGCCACGCCCGCCGCCCTCAACGCGgccgcaacggcagcggcggcgaacGCCAGCGCCCTCAGTCCCGCTCGCAGCCTCAGTCCGACCGCGgttggcgtcggcgtcggcgtcccATTGCCGCTGCACGCGCTGATGGCGCAGGCCGTGGcctcgcagtcgcagtcggcgtcggcgtcgccagcgccaaagcgcagcagcagcaacagcagcgccgccgcctccaTGGGCGGTGCAGGAGGCGTGGCCTCGGCCaacacgagcagcagcagcagtgcgagcagcggcagctcgcccacacagcaactgttgcaggtgcgtgcacaacagcaacaccagcagcaccagcagcaacagcagcagcagcaacaacatcagcagcagcaacagcagcagcagcagaacatgGCCACAGCGATGGCGGCGGGCATGCGTCACCatccgctgctggcgccgccgGAGGCGATGCACGCGAATCCGTTCCAGCTGCTGCGGATGCCGCTGCCCCCCGCGCTGGCCCAGGCCAATGTAGTTCCTAGCGTGGCGCCGCTCTTCGGCCGCCCCTCGCCCGCCGACCACTATCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGGCACCACGGCTTCAAtctggccgccgccgctgccgctgcccagGCGCAGTTCAACGccagcaaccagcagcagcagcagcagcaaccgttGCAGGCGGTTGCTGTCAACGTTCCTAGCGGCATCGAGCAGCGGCCGCCctcaagcaacagcagccagcgcgGTTCCGTTCCGCCTGCCGCACTGCCACCGCCCTCGCTCagctcccagcagcagcagcaacagcagcaacaacagcagcagcagcagcaacaacagcagcagcaacaacagcaacagcagcagcaggctgctgccGTCAGtccagcaactgttgctggtgccGCGCTGAATTTGGAGCCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCGGCGCCGACGCCGCGCCCCCACTCGCGCACACCGCCCGAGAAGGCCGCCGAGAATGGCGGcagccaccaccagcagccgcCGAGCACGCCCCGCTCGGCCAGCACGCCGCCAACgggcgccggcagcggcgccaACATCAGCGCCAATGTCAGCGCCGACGCGGAACGGAGCGCAGCGGAGCTGGAGGCGAGCTGCTTTGCGTGTGGGTACTGCGACAAGAAGTTCCGGTTCGAGAACAACCTGATCATCCACCAGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGATTTTGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGTCCCGCCGAGGGACacgacggcggcagcagcaatggcgGCGACAACAACCAGGACGGACACGATGGCGGCAGCAATGCCGACTCCCTGGAGACGAACGAGGCGGACAACGACGACGATCCGAATCCGGACGAGTCCGACGACGAGCTGAACGAGGAGGACGCCGATGCCGATGGCGATGCTGATGGCGATGGCGAGGACGATGACGAGGATGAGCTGGAGGATTGCGAGGATGTCGACTATGAGGCCGAGGATCTGAGCGTCAACAATCGGATCGACGGCAAGAGCCAAAGCCCCAAGACGACCAGCTCGGGCGCCACCTCCCTCGTCGGCGAGCTGATGGACAAGTTCGGGCTCTCGAACATCGCCCAGTACTCGGAGGCGTACAAGCAGGCGCTGCAGGAGTCCGGCCGGAAGGAggccgccgctgttgccgccgccgcagcagccgccgctgccgttgacaacaacaatcgcggcggcagcagccgcgACCCCGCCGGCGCCGACAAGCTGAACGGGCTGCCGGTGGCGGCGCTGCGGCTGCGCGACGAGTTCGCCAAGAACTGCAACATGTTCCAGGCGCAGCAGCCGGACGGGCCCGCCCAGGTGCCGCTCTTCAATCCGTTCCCGAATCCGTTCGAGCTGTCCAAGCGCATGAAGATGGACGGCGGCGACTGGTGGGGCATGTCCGCGCTGCACCGCAACGAGGCGCTATTCGAGAACCTCAAACTGAAGCCGCTGGGCCTCGGCGGCGCCAACTCGCTGCTGCAGGGCCCGCTCCTGAAGAAGGAGTCGCGCCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCACCGGCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAACTGTGCAGCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACCCACGGACGCACCGGCAAGGATGTCTATCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGcaaagcagccgccgccgctgccaatgCGGCCaatgctgttgccgccgcccaagcggccgctgccgcccagcagctgcaggcggccGCTGCccaggcacagcagcagcagcagcaccaacaccaacaccaacagcagcagcagcagcaacaacagcagcagcagcaacagttgccaacGCAGTCGCAGCTGTCGCCGCCCTGCCcgatgggcgtggccgtgggcTTCCCGCCGCAGTTCAACGTCGGCCACAATCTGTCGCTGGCGGGCAGCGTCAGCGGGGACAACGATTCGAACGCATCCTCCAGCCTGCCCGCGCACTCCATCTCCCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKILSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVAVAPPNAAAAAAAAATAAATAAAAAAAAASAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADGEPLTTAPLEASSGSAHSPSHAHSEQTQPQLASRPSPSPDCALNDDKPKVKQEPYADDDLPQDNNNEDEQPDQQLLTPTPTANQTATETQQPPAADECQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEAGGGATLTVATPAALNAAATAAAANASALSPARSLSPTAVGVGVGVPLPLHALMAQAVASQSQSASASPAPKRSSSNSSAAASMGGAGGVASANTSSSSSASSGSSPTQQLLQVRAQQQHQQHQQQQQQQQQHQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQANVVPSVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNASNQQQQQQQPLQAVAVNVPSGIEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQAAAVSPATVAGAALNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAAPTPRPHSRTPPEKAAENGGSHHQQPPSTPRSASTPPTGAGSGANISANVSADAERSAAELEASCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGHDGGSSNGGDNNQDGHDGGSNADSLETNEADNDDDPNPDESDDELNEEDADADGDADGDGEDDDEDELEDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGGSSRDPAGADKLNGLPVAALRLRDEFAKNCNMFQAQQPDGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAAQAQQQQQHQHQHQQQQQQQQQQQQQQLPTQSQLSPPCPMGVAVGFPPQFNVGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547608;
90% Identity: iTF_00567767;
80% Identity: -