Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: HIVEP2_1
Assembly: GCA_004149445.1
Location: SCDR01000534.1:40573-50728[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0002 0.024 15.6 2.9 1 21 135 155 135 159 0.89

2 7 0.029 3.4 8.8 0.2 1 19 352 370 352 373 0.93

3 7 1.8e-06 0.00022 22.1 2.0 1 23 1138 1160 1138 1160 0.99

4 7 7.6e-06 0.00091 20.1 5.3 1 23 1166 1190 1166 1190 0.92

5 7 0.00011 0.013 16.4 3.1 2 23 1644 1665 1644 1665 0.97

6 7 0.00052 0.062 14.3 1.2 1 23 1671 1695 1671 1695 0.91

7 7 0.0017 0.2 12.7 2.7 1 23 1716 1740 1716 1740 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0002	0.024	15.6	2.9	1	21	135	155	135	159	0.89
2	7	0.029	3.4	8.8	0.2	1	19	352	370	352	373	0.93
3	7	1.8e-06	0.00022	22.1	2.0	1	23	1138	1160	1138	1160	0.99
4	7	7.6e-06	0.00091	20.1	5.3	1	23	1166	1190	1166	1190	0.92
5	7	0.00011	0.013	16.4	3.1	2	23	1644	1665	1644	1665	0.97
6	7	0.00052	0.062	14.3	1.2	1	23	1671	1695	1671	1695	0.91
7	7	0.0017	0.2	12.7	2.7	1	23	1716	1740	1716	1740	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCATGTGGCTAGCAGCGCATCCAGCGTGGCCAcaaccaccaacaccaccagcagcagcagcaacaatagcagcagcaacaacagcagcagcaacactgtGGTGCCAGCCAGCGCTGatgcggcagcagctgttgcagcagccgcCATTGTCGATTGGACGAACTCAAACAATTTGCGCtatttgcacaaaaagttTAAGCGCTTGGCCAGCACCACCGAACCGGAGACGGGCGATGTGGTGCGCACCACATCGCTCTCCTCGAACAGCTCGCTgtcgccaccgccgccgccgccgtcgtcgtcggcgtcggcgtcggttGCGCCGTTGGCCAATGGACACATGACGTTGCTGCTGGCTAAAAATGAATTCACGCACACCAACGAGCGTCCGTATCCGTGCGACACCTGCGGCATCGCCTTCAAAACGAAGAGCAACCTCTACAAGCACTGCCGGTCGCGCTCGCACGCGGCGCGCAGTCGCGGCTACGATGTGCCCGCCCACGAGGCGGACGGCATGTCCGATCAGGACGGCGACGGCGAgctgagcaacagcagctccgaGCTGCTAAGCGTCGAAGTGCTGAGTCGCGCGGATTCGCCTTTTGACGAGCCGATGGCCTCGCcgacgccatcgccatcgacGCTGTCGGCTGCGAAGAGCGCCTACTTGCAACAGCCGCCGTTGCCGCAGCAcatgcaacagctgccgctgggCTCGCCCGCTGCCGGCACACTGCCGCCCGCCACCGCCGACACGCTCCACTCGGCGACGGCGCAGCATCGCCAATCGTTCGACTACAAACCCCAACAGACGTCGATCACAGCGACCGCAGCAGCGCTGCCTgcgcctgccacgcccacagcgacACCGACGCCCACTGCCAATCTGAGCAGCTttgccagcgccagcggcggcatGCAAGTGAATGTGGAGAAGGTGCAGGAACACATCTCGAAGCTGATCTCACAGAACGAGGCCATCAATCTGCTGCTGAACGCACGCGGACTGGCCGTCCCAATTGGCGAGGGCGACGATGCCGTCTACTCGTGTCCCATCTGCGCCAACGAGTATCGCAGCGCCGACGAACTGAAGCACCACAACAGCACCTACTGCCAGGACGCGAGCAGCAGTGCACCGATCAGTCCGGCCTCCTCGCCCGGCACCAAGTTCTTTCGCTCCAATTCCATATCGTTGAGCTTGCCGGAGCTCAAATCGCACATGGCCAACTCCAAGAATCCGCTGTCGCTGGCCAAGCTCGCCTGGTCCCAGCTGAAGACGAAGCCCAGCAGCCTGGTCCTGAGTCGCCTAAGTGCGGCGCAGTCGCCGGCGCGcaccgcaacaacagcaacagcagcgagcagcagcagcagcagcagcggcaacaacaactgtaacaacaacaacagcagcagcaacaccccagcaacagttgcagctgccatTCCGCCCAGCATCGATGCGGGCGTCGCTCTGCGCTTTGTGGACGCGCCGCTGCCATCGCCGGGTCCGCTGCTCGGCAAGACGCCGCTGGTGGATTATGCGGCGCCGCGCAAAGCGCCCGATGCCCAAGTGGTGATCACCAAAATGCACGAGGATCGGCTGGAGAATACCATCGGTGAGACGGCCGCCAAGCGACCAAAGCTGAGCAGCGACATTGCCagctccagcgccagcgccagcgccagttcGTCCTCGTTTGCGGGCGTTCAGCTGCTCTTTGGCGGCAATCAGGAGCTGCATGCTGgtgccgtcgccgccgccgctggcatTTTCGGCACCAAAGAGGAGCGTCTGCGTCGCTTCACCTCCTCCGGCGGCACCATGATACCCATCTCCGAGTGCCCCGACCTGGACAAGAGCCCCAAAATGATACGCACTCCGCTGCTCTCCGGCGGCAGCTTCCAGGAGATGTCGCCGCGCATCAGCGACAGCAAGGAACGCAAGCTGGCCAACAATGGCTACCTGCTCAGCGCCGCCGTCGCGAACAGCGCCAATCACTTTCAATATCCGCCCATCAATCCGATTACCGCCTTCAATCCGCTCACACTGCCAAGCCTAAGTGGCGGCGACGCCTCCGGCAAATCGATACCGTACGTGCCCGGCATACCGGGTCCGGGCAGCCtctcgctgctgccgccgccgccgcagcagctgccgcgcGGTCGCAGTCCCAATCGCAAGCAGCCCAGTCCCAATCCGAACCTGAATCCCAATCCGAATCCAAATCCCTTGCTGGCCGCTGCTGAGGCGCCGCTCAAGTCGCTGTCGCCCTTCGGCGGCGTTCAGAATTTGCCCAGCGAATTCAGTCGCCAGCCGCCGACGCCCGCCCAGCGCAATGCGCTGCACtggaccaacaacaacaacagcagcaacagcagcagcaacaacaacagcagcaacaacaacaacaacaacaacaacaacaacagcagcagcagcaacaacaacaacaagctggaAACGTTGATCAAAAAGGCGCCGTTCAATTTCCTGCGCATGGCGGATAATGTGAAGAGCGCGGAGGAAGTGCGTCACTTCAATTTCGATAGTGTGCACAAAACGCAGGAggcgctggcgccgctgcaCGTGGAAACGCCCGAggagacaacagcaacagcagcagcagcagcaacaatcacagtaacaacaacaacaacaacaacaacagcagcagcaacaagtgccAAATCCAAGTTTCTGCGACCCACCAGCTTGCCACTGAAGCCGGGCACATTTACGCCGAAGCGTCATCACGGAATCACACCGACCGCGAATACCCTGCCGCTGATCTCGCCGGAAACGCCGCGTCCTTCCAAATCGTGCGTGCAGCTGTATTTAAATGGCCACGCCTACACGTATCTGGGACTGAAGTGCAGCACGAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCGTCGTATGTGGCCGGAATGCACAAGCTGTCGATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTCGGCTTCAAGCCGCGACAGGTGATGGCCCTCTACGATTCCCGGCAGAAAATGCTCGGCGCCGGCTGCTCGACGGCCATGGCCGGCGCCGGGAAGCTGCACTATGCGCTGGTCAGTGCCCAGCAGACggtcagcagctgctcgacaaCGGCCAACGGGCAGAACAAGTTCTACCAGCatcaacaacaccaacaacaccatcagcagcagcagcagcagcagcagcagcagcagacacaaCAGTCGCCCAAACAGCCGCCGGCAATTGGAGCGCTCAGCGAGGCGAACGTGGCGGCCAAAGCCAGCGAGGAGGCGGCCGCCAAGAAACTGGAGACGAGCCAACTGCTCGTCGGTGGCTACGAATCGCACGAGGATTACACGTACATACGGGGACGCGGACGTGGCCGTTACGTGTGCTCCGAGTGCGGCATCCGGTGCAAGAAGCCATCCATGCTGAAGAAGCACATACGCACCCACACGGACGTGCGTCCGTTCACCTGCAGCCACTGCAACTTCAGCTTCAAGACCAAGGGCAATCTCACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAGTGCATCGAACTGGGCATCAATCCGGGTCCGATGCCAGCCGATGGCGAGTTCCTCGATGTCGATGTGGAGTTCGATCAGCAGTCCTCGACATCCGCCGGCGGACGCACCTCCTCCATGGCCGGCGAGTCCGACTCGGAGGATTACAGTGACAACGAGTCCGAGAGCAGCGACACGGACGAGTCCAAGTCGCGCATGAAGGAGCACGAGGCGGCCCGCGgtctgttgtcgctgtcgatGACGCCGCCGATACCGCAGAGCGTGTCGCCGTATCCGGCACAGCTGCAGGATGCGCCCGTGCCGGCGGGCAGTCCGGCGAACAGCATTGGCTCCTCGGCGGGCAGTGCGGCCGGCGGATCGCAGCCGAAGCGTTTGGTCTGCTCGTTCACGTCGCCAAAGCCGCCGTTTGATTACCAGAAACAGGAACAGTATTACTCGAATCCGGAGGAGTCGAAGCCCAAACGGGGCGTGCCCAGCGATGAGAGCAGCGCACCGATGGACCTAACCAAGCCGCGCAGCCTGACCAGCGGCAACGTGGCGCCTTCTGAGCAGACGCTGCCCAAATCGCAGGCACAGCAGATGCGGGACGTGATCTTCGGAGCGGGCAACAACGAGTGCGGGTTCATGAAGACGCTGATTTCGGTGTCGGACAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCGAAGCGCAAAAGCGACGGCGAAGATCTCCTACTGCAGACATACATCAAggagcaggcgctgcagcatGCCAAGATGAAGCAGAGCCAGTTCAGTCGCAGCTACCTGGtgaccagcaccagcagcagcaccaccaccaccatcagcaCCACCATCAACACAACGCCCATTGTCAGCAGCTGCCTGCCCAAGCCAACCATGATCATCACAGAGCTGCCCAGCATCGAGGTGCACGAGGTGAAGACGCCCGAGCCGCCAGCGGCCAATTCCGCCGACGGAGAGAGCGAAGAGTGCGACGAAAAGCTAAACACCGAAACGGAGCTGCCCGTCAAGTTGGTGTCGGTGCTGCCGGTTGCCAAGTCGCCGCCACACAATGCCAATTTGCCCGCTGCAGTGCAGCAGCCGGATGCGACCGATTTCAGTGGCgtgctgagcagcagcagcagcagcaacaacaataacaacaacaatgggagTGGAGGCAGTGCAGCCTCAACGGCCGCACGCACCGTCATCGTCGGCGAGGAGGGCTTCAAggcgacgccagcagcaacaacagcgacaccaacaacaacgtcgaCGAGCAGCGCCGGCGAGCCGCTAACCGGCAGCTATCCGGGACGCGTggtggcgccgccgccgccgccaattGCCAGCGATGGGCGGCCCACGTGCGTCCTGTGCAACAAGACGTTCCAGCGCCAGCATCAGCTGACCCTGCACATGAACATCCATTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGGACGCAGGGCCACCTGCAGAAGCACGAACGCTCCGAGGCGCACCGCAACAAGGTGATGATGACGTCGACTTTCGGGGTGCCGACCACATCGAATCCGCGTCCGTTTGAGTGCACCGACTGCAAGATCGCGTTTCGCATACACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACGCACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCGTTCGGCACCTATGCGGAGATCGAGCGGGCCGGGATCAGTTTGACGGACATCGATACCAGCGACTGCGAGAATTCGCTCATCTCGCTGAAGCAGCTCGCCCAGAAGCTGCTCGAGAAGGATCCGAACAAGCTGAGCGGCTACACAACGCCATCGGGCATGCTCCAGCTGTCCGCGGAACCGCCAGCCGCCGGCCAGGACAGCGCCTCCGAGGACGGCTTCAGTGCGGCCAACAGCGCCGCCGCCTCGGCGATCGCCTCGCTGGACAACGACAGCGCCGGCAACACACCGCAGCGGGCCAGTTCCATGTCCGAGGACGAGACGCTCACCAACGGACTCGGCCACacgcacagccacagccagagtcacagccagagccagagtcagagtcaCGGGCACAGCTTGAAGCGTCGCCTGCCcggcagcagctacagcagcaacggcgacgAGAGCGACAATCCTCTGGAGagcagcgtcggcgtcggcgtcggcgagAAGCGCGCCAGGAGCAACACCAACGAGCTGACAGCGCTGCCGGTGGCTGCGTCCGCGGCGACGGCCAGCAACTGA
Protein Sequence: MTLQHVASSASSVATTTNTTSSSSNNSSSNNSSSNTVVPASADAAAAVAAAAIVDWTNSNNLRYLHKKFKRLASTTEPETGDVVRTTSLSSNSSLSPPPPPPSSSASASVAPLANGHMTLLLAKNEFTHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARSRGYDVPAHEADGMSDQDGDGELSNSSSELLSVEVLSRADSPFDEPMASPTPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPATADTLHSATAQHRQSFDYKPQQTSITATAAALPAPATPTATPTPTANLSSFASASGGMQVNVEKVQEHISKLISQNEAINLLLNARGLAVPIGEGDDAVYSCPICANEYRSADELKHHNSTYCQDASSSAPISPASSPGTKFFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTATTATAASSSSSSSGNNNCNNNNSSSNTPATVAAAIPPSIDAGVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENTIGETAAKRPKLSSDIASSSASASASSSSFAGVQLLFGGNQELHAGAVAAAAGIFGTKEERLRRFTSSGGTMIPISECPDLDKSPKMIRTPLLSGGSFQEMSPRISDSKERKLANNGYLLSAAVANSANHFQYPPINPITAFNPLTLPSLSGGDASGKSIPYVPGIPGPGSLSLLPPPPQQLPRGRSPNRKQPSPNPNLNPNPNPNPLLAAAEAPLKSLSPFGGVQNLPSEFSRQPPTPAQRNALHWTNNNNSSNSSSNNNSSNNNNNNNNNNSSSSNNNNKLETLIKKAPFNFLRMADNVKSAEEVRHFNFDSVHKTQEALAPLHVETPEETTATAAAAATITVTTTTTTTTAAATSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPRQVMALYDSRQKMLGAGCSTAMAGAGKLHYALVSAQQTVSSCSTTANGQNKFYQHQQHQQHHQQQQQQQQQQQTQQSPKQPPAIGALSEANVAAKASEEAAAKKLETSQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSEDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPAQLQDAPVPAGSPANSIGSSAGSAAGGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPSDESSAPMDLTKPRSLTSGNVAPSEQTLPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRKSDGEDLLLQTYIKEQALQHAKMKQSQFSRSYLVTSTSSSTTTTISTTINTTPIVSSCLPKPTMIITELPSIEVHEVKTPEPPAANSADGESEECDEKLNTETELPVKLVSVLPVAKSPPHNANLPAAVQQPDATDFSGVLSSSSSSNNNNNNNGSGGSAASTAARTVIVGEEGFKATPAATTATPTTTSTSSAGEPLTGSYPGRVVAPPPPPIASDGRPTCVLCNKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTDIDTSDCENSLISLKQLAQKLLEKDPNKLSGYTTPSGMLQLSAEPPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLTNGLGHTHSHSQSHSQSQSQSHGHSLKRRLPGSSYSSNGDESDNPLESSVGVGVGEKRARSNTNELTALPVAASAATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -