Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: L
Assembly: GCA_004149445.1
Location: SCDR01001157.1:4005-13253[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9e-06 0.0011 19.9 2.9 1 23 167 189 167 189 0.98

2 17 0.31 37 5.6 6.2 1 23 195 217 195 217 0.97

3 17 1.5e-07 1.8e-05 25.5 3.2 1 23 223 245 223 245 0.99

4 17 1.1e-05 0.0013 19.6 0.4 1 23 251 273 251 273 0.99

5 17 0.011 1.3 10.2 0.2 2 23 347 371 346 371 0.92

6 17 0.00071 0.085 13.9 0.2 2 23 402 424 401 424 0.95

7 17 0.094 11 7.2 0.4 1 23 502 524 502 524 0.95

8 17 0.067 8.1 7.7 0.1 2 23 532 553 531 553 0.91

9 17 0.00021 0.025 15.6 0.2 1 23 561 585 561 585 0.94

10 17 4.4 5.3e+02 2.0 0.9 2 23 621 643 620 643 0.94

11 17 0.0022 0.27 12.3 1.1 1 23 707 730 707 730 0.97

12 17 0.0057 0.68 11.1 1.6 2 23 911 933 910 933 0.96

13 17 0.1 12 7.1 0.1 1 23 939 961 939 961 0.92

14 17 1.2 1.5e+02 3.7 1.2 2 23 969 990 968 990 0.93

15 17 0.35 42 5.4 1.2 1 23 1089 1111 1089 1111 0.94

16 17 0.027 3.2 8.9 0.0 1 23 1121 1143 1121 1143 0.95

17 17 0.00067 0.08 14.0 2.0 1 23 1148 1170 1148 1170 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9e-06	0.0011	19.9	2.9	1	23	167	189	167	189	0.98
2	17	0.31	37	5.6	6.2	1	23	195	217	195	217	0.97
3	17	1.5e-07	1.8e-05	25.5	3.2	1	23	223	245	223	245	0.99
4	17	1.1e-05	0.0013	19.6	0.4	1	23	251	273	251	273	0.99
5	17	0.011	1.3	10.2	0.2	2	23	347	371	346	371	0.92
6	17	0.00071	0.085	13.9	0.2	2	23	402	424	401	424	0.95
7	17	0.094	11	7.2	0.4	1	23	502	524	502	524	0.95
8	17	0.067	8.1	7.7	0.1	2	23	532	553	531	553	0.91
9	17	0.00021	0.025	15.6	0.2	1	23	561	585	561	585	0.94
10	17	4.4	5.3e+02	2.0	0.9	2	23	621	643	620	643	0.94
11	17	0.0022	0.27	12.3	1.1	1	23	707	730	707	730	0.97
12	17	0.0057	0.68	11.1	1.6	2	23	911	933	910	933	0.96
13	17	0.1	12	7.1	0.1	1	23	939	961	939	961	0.92
14	17	1.2	1.5e+02	3.7	1.2	2	23	969	990	968	990	0.93
15	17	0.35	42	5.4	1.2	1	23	1089	1111	1089	1111	0.94
16	17	0.027	3.2	8.9	0.0	1	23	1121	1143	1121	1143	0.95
17	17	0.00067	0.08	14.0	2.0	1	23	1148	1170	1148	1170	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagattCAAGCCACCAAGGAGATTACAAATAACGATATGTACAGCACGCACACCTCCTCCAGCTACTCGCCAAGCATCTCCGATGGCACTTTGACGCCCAATTCGATGCcgcagctggcggcgcaggGCGACGAGTCCACGGCGGAGACGAAGGCGAATGGGGAAGCTGTGTCCGCCACAggggaggagcagcagcagcagcaacagcaggagccAATTAGGCCAAAGCGGCCGGCACAtttgcatcatcatcatcaccatcattatcatcatcagcaggcGCTAAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGATGCGAAATTGCTAACTGGAACAGGATCGGGCGGCGCAGGACAACCCGGACACAATGCAGCGGGAGCCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGCCGTGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGaGCCATGCCGAACATTTGCCGTTCAAGTGCGAATACTGCGCCAAGTTGTTCAAACACAAACGCTCCCGAGATCGCCATAAGAAGCTCCACACGAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCGGCTTTCTCCAGAAGCGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAACCGTTCCAGTGCAGCATGTGCAATCGCGGCTACAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCGGCCATTTTGGCGGCTGGCGGTAATCCGAACGCACTCAACTACAGTCCCAGATCGACGGGATCCGCCTCGATATCGAGCAATGGCAGCCTGCACAAGCGCCGATATGCGCTGGCTTTGGCCACCGACAGCAGTCCGAGTCGCCTCGATTTTCCGAAACGGGCGCGTACCCAGCTGgcggctgccacgcccactccgaCACCGCTGCTGCGCTGCAGCTACTGTCCCAAGGTGACGGAGTTCACCAGCCTGGAGCAGTTGAATGCGCATCTGCAGAGCGTccacgagcagcagcagccgcagcagcagcagcagacgccacCAGCCGATGGCGATGGGTGCGTCGTGGAGCAGGCGGCGAACGGTTTTCAGCTGAGCTGCGAATATTGCACGATGAAATTTGTGAATATTGCCGCGCTCTTTCAGCACATGCGCGGCACACACCTGGACCGGCTGAGCAGTCCGAACTCGTATTACGAGCACTTCAATCGCTTGGCCACGGCTGGCACGTTCAGTCCCCGTTTGGCGGTGGAGATGCCCAAGCACATCAAACAGGATGCGGATGCGAAATTGGAGCAACAGGAGCTGCCAACGGATttgagcagcaacaagcgGCGTCCGTTGACGCCGCAGCCAGCATCagtgccagcgccagcgccagcgccacctGGCGTCTTCCTCTGCAACCAGTGCAATGCCGGTTTGCCGGACTTTGAGAGCTTCCGCAATCATCTGAAATCGCACATCGTGGAGGGCATGCAGCTGAGCTGTCCGCACTGCGGCCTCAATCTGCCCGAGCAGGGCGAGTACGAGCGGCACGTGGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAattgcagcgccagctgcggcAAGTCCTACTCGAAGGcggaggagctgcagcagcatctgctgAGCGAGCAtgtccagcagctgctgaagtGCGTCCTCTGCTCGGAGCTGTGCGAGAATCGGATGTCGATGCAGCTGCACTTGGCCTGCGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTGTTTCGCAGCGATGCCGAGTTCCATGTGCACGTCAAGACGCGACATCAGCTGGgcggacaacaacagcaacagcaacgggagcgagaacgggagcgggagcgggaacaGCAGcgggagcaacagcagctgagtGGCGGCGGGCCATCCTCGAATCCGCTGCAGTGCATGTTTTGTCGCGTCGTTTGCGCCTCGGAGCTGGAGATGCATTTCCATTTGGCGGCGCATGCGCGACAATTTCGCTGTCCCAGCTGCCCGGAGACATTTCACGTGGAGTTCCTGCTCGATCGGCATATGCAGAGCCAacacggcggcggcggcggcggcggcaccatCAAAGGAACCAAGGAACCGGGCGCGGCTGCCGCCAGCATGGGCAGTCTCTATGTGaatgcgctgctgccgccgctggcagcggccgctgctgctgccgccgcggcgacaaacaacaacagcagcctgcACATCGACTACAACGTGGCGTTCAAGGGCCTGTTCGGTGGCggcaatgccacgcccacaaatcCACAAGCCAAATTCTATAGTCCGCTGCAGGTGGACACCAAAGCGGCGCAGCAGGCGCCACATCCGGCGCTGATGTACGGCCTGAGTCAGCGCTATTTAATGGAAATGTACGCGGCCAAAGCGAATTCGCCGGCAACAAGCGGAGCCGAGTTGCCACCACAAGCGCCGCCCAATGTGGCAGCTgccgttggcggcggcggcggcggcggcggcagcgctgccaactaCAGTTGCGGGATGTGCGAGCGTCAGGATTTGCGCAGCGAGGCCGAATTGCATTCGCACCGGAAGCTGGCGCACAATCTGAAGACGGGCGTCAGTCTGAGGTGTGCCTACTGTTCCGGCAATTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGTCACAATTCGAGCGGCAAGCACAAGTGTCTCATTTGCGATGAGATCTTCCCGTCGCCCGCGATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGACAGTCCGGCAAATGCGCCCATTGCGGCCACCAGCTGGAGCATGTGGCCGCCTTCCGGGCGCATCTCGGCGAGCACGGCAACGATGGCAATCTGCCGATGGCCTGCATCTGTTGCCGGCAAACGCTTCACTCGGAATTCGAGTTGAGCCTGCACGCCAAATTCCACACGAAATCGTCGCCGGGCTGCGGCAGCCTCCAGGAACCGGTCTGTGCACTGTGCCTGGAACCGCTGCCAGGCGCCGGTGAGACGGCCAAATTGTGCGACAAATGCTGCCGCAAACACAACTTAAATGGCAAGCGACACAAGGAACCAGCCACCCTGGTGCTGGCACCAAGCACGAAGACAACGAGCACGGCTGCCTATTTGGAGCACCGTTGCAATCTGTGCAAGCTGATACTGCCGCACGCCCAGAAGCTGCAGGAGCATCTGGTGGAGCACACATTCGCCGGCACCGAGCAGCGCGGCTTCAATTGTTACATCTGCTCGGCGGTGTTCACAGCGCCCGCCGGCCTCCTCAGCCACATGGGGGAGCATGGGGCGCGGCCCTACGATTGCAATCTGTGCACCGAGAAGTTCTATTTTCGGGCCGAGCTGGAGCACCATCAGCGGGCGCACGAGCTGCGACAGCAGACGACCAAACAGGAGACTGAGATCAGCTCCGCGGCCAGTTCACCGATGACGCCGACGAGTCCACTGCACGCGGTTAAGCAGGAGCTATACGAATCGGAGCCGGGCACATCGCCCAGCGGTGAACCGGCTGCCGGCGACGAGGAGGAGTACATCGAGGTGGAGCAAGTGCCGCAGGAGACACAACGAACGGGAGAGCTGCTCAGCACcgaacgcagcagcagcagcgcctaa
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSMPQLAAQGDESTAETKANGEAVSATGEEQQQQQQQEPIRPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLLTGTGSGGAGQPGHNAAGAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALATDSSPSRLDFPKRARTQLAAATPTPTPLLRCSYCPKVTEFTSLEQLNAHLQSVHEQQQPQQQQQTPPADGDGCVVEQAANGFQLSCEYCTMKFVNIAALFQHMRGTHLDRLSSPNSYYEHFNRLATAGTFSPRLAVEMPKHIKQDADAKLEQQELPTDLSSNKRRPLTPQPASVPAPAPAPPGVFLCNQCNAGLPDFESFRNHLKSHIVEGMQLSCPHCGLNLPEQGEYERHVVAHFLISSSEFNCSASCGKSYSKAEELQQHLLSEHVQQLLKCVLCSELCENRMSMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGQQQQQQREREREREREQQREQQQLSGGGPSSNPLQCMFCRVVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGGGGGTIKGTKEPGAAAASMGSLYVNALLPPLAAAAAAAAAATNNNSSLHIDYNVAFKGLFGGGNATPTNPQAKFYSPLQVDTKAAQQAPHPALMYGLSQRYLMEMYAAKANSPATSGAELPPQAPPNVAAAVGGGGGGGGSAANYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSSPGCGSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRHKEPATLVLAPSTKTTSTAAYLEHRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHMGEHGARPYDCNLCTEKFYFRAELEHHQRAHELRQQTTKQETEISSAASSPMTPTSPLHAVKQELYESEPGTSPSGEPAAGDEEEYIEVEQVPQETQRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00541932;
80% Identity: -