Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01000198.1:88075-90610[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.025 3 9.0 4.0 1 23 274 296 274 296 0.98

2 11 1.9e-06 0.00023 22.0 0.3 1 23 302 324 302 324 0.99

3 11 0.00019 0.023 15.7 4.2 1 23 330 353 330 353 0.97

4 11 0.31 38 5.6 3.8 1 20 359 378 359 381 0.95

5 11 0.0077 0.92 10.6 1.7 1 23 387 409 387 409 0.97

6 11 0.00034 0.041 14.9 0.8 1 23 415 437 415 437 0.98

7 11 0.00011 0.014 16.4 1.9 1 23 445 468 445 468 0.97

8 11 0.0036 0.43 11.7 0.4 3 23 476 496 474 496 0.97

9 11 0.2 23 6.2 4.8 1 23 502 524 502 524 0.98

10 11 0.00011 0.014 16.4 2.0 1 23 530 553 530 553 0.95

11 11 5.3e-06 0.00063 20.6 0.5 3 23 569 589 568 589 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.025	3	9.0	4.0	1	23	274	296	274	296	0.98
2	11	1.9e-06	0.00023	22.0	0.3	1	23	302	324	302	324	0.99
3	11	0.00019	0.023	15.7	4.2	1	23	330	353	330	353	0.97
4	11	0.31	38	5.6	3.8	1	20	359	378	359	381	0.95
5	11	0.0077	0.92	10.6	1.7	1	23	387	409	387	409	0.97
6	11	0.00034	0.041	14.9	0.8	1	23	415	437	415	437	0.98
7	11	0.00011	0.014	16.4	1.9	1	23	445	468	445	468	0.97
8	11	0.0036	0.43	11.7	0.4	3	23	476	496	474	496	0.97
9	11	0.2	23	6.2	4.8	1	23	502	524	502	524	0.98
10	11	0.00011	0.014	16.4	2.0	1	23	530	553	530	553	0.95
11	11	5.3e-06	0.00063	20.6	0.5	3	23	569	589	568	589	0.99

Sequence Information

Coding Sequence: ATGTCAAACCGTACGCGCGACTCCGAATCAGAGGACTTGCAGtcctttttattaaattttcacaagGAAATCGAGGATGGTAGCGTCGATGGCAAGGATGTCAAACCACCCGATGATGATGCcgaggaagaggaagaagaagagcaagagGACCAGGACGATAATGATGACGAATTCTTTATTGACGACGAAGGCAACTGTTATATTAAGACCACGGCAAAGAAGCAACAAGAACTCAAAAAGAAACTCACGTCACAAGCAACCTCAAAGGCGGCGTCGGCACAAGAACCAATCGCAATACGCAGCGCTACCCGTGCTGCCAGCAGCTCAACTTCTAAGGGTATAACCCTGCGTCCAGCCAAAACCAAATCGTATTCATCGCCGCAAAAGACGGCCAAAGCAATTAACATACGTCCCGCTCCTCCGAAGAGAACGCCCCCTAAGACGACTTCGACACCAGTTAGCATGTCCAAAGCTAATCTACGTTCAACAGATGTCAAGACTTCTGCCAAGGCAGTAAGAGAGGAATCTGAGTCAATGCCTCAGCACAGTAAGGTAGTGATAGAGAAAGTGGAGGAATTCGAAGAACTTGTGGATGATCCAAGTGGCGTTGATGAAACTGCGATATCCATTGACGAATCGGAACTAACTCTCGGAAATGACGATTCACTCGAGAGCAAAAATGAGTCAGATGGTAAGGTCTACGAATTCGACGACAATATAGCCAATATGTCCGCCAAGTCGGATGTGGACTTTGTGCTCAGCGGCAATCAATATAAGCTGAAACCGGTGGCGACCAACTCGGAAGGAGCGCAGAAATACGCCTGCTCCCATTGCAGCTACACGACCAATAAAAAATTCCTAATCTCACGCCACGTGCGCACGCACGGCGCGGAACGGTCATTCAAGTGTTCTATATGTGAGCGCGGCTTCAAGACCAACGTAGGCCTGATCAATCATATCAACACGCACATGGGCAACAAGCCGCACAAGTGCAAACAGTGCGACAGCAAGTTCACGACCAGCGGCGAACTCGTACGCCACACACGCTACAAACACACCAAGGAAAAACCGCACAAGTGCACCGAGTGCAGCTATGCCAGCGTCGAGCTAACCAAGCTGCGTCGCCACATGACCTGCCATACGGGCGAGCGTCCATACCAGTGTCCGCACTGCACGTACGCCTCGCAGGACATGTTCAAGCTGAAGCGTCACCTGGTCATTCATACGGGCGAGAAAAAGTTTCAATGCGACATATGCCTGTCACGCTTCACACAATCCAACTCCCTCAAGGCCCACAAACTCATCCATAGTGTGGCGAACAAGCCGGTGTTTCAATGCACCCTGTGCCCCACAACATGCGGCAGAAAGGCTGACCTGCGCACCCACATGACCAGCATGCACGCCTCGGATAAGCCGATCGCGTGCAAGCGCTGCGGCCAGCAACTGCCCGATCGCTATCAGTATAAGCTGCACATTAAGTCGCACGAGGGCGAGAAATGCTACAGTTGCAGCTACTGCTGCTATAGGACCATATCCCAGCGGCATTTGGAATCGCACTTGCTTATACACACGGACTCGAAGCCCTTCAAGTGCGACTTGTGCTCACAAGAGtttcgacagcagcagctgctgcgtcgTCATAAAAATCTTATGCATGATGAGGGCTATAAGAAGCCGAAGCCGCGCGAAAAGGTGCACGGCTGCCCAGGCTGCGCACGTGTCTACACGCACAAGGGAAACCTAATGCGCCACATGGAAACACACGATGATGAGCTAAATGTGCGCGAGGCGAAGCTTAGGCTTAAGCTGGGCCGGAACGTACGCCTGCGACCGGACGGCAGCGTTGTCAATGTGGGCAGTAGCAGCGTCGTTGATGAACTTGGCATTAGCGAAGCCATTTCCTTTGATGAGCAATTCGAGATTACTGAGCTAGAGGAAGTGGATgaggtggaggaggaggaggaacagCCCAGAGTAATTGTTGAGGAAACGTTTACGAAACCCACCTCTAGAACgaaagagcaaaacaaaacggtCGTATCAAAGGACCGCGAGCAGAGCTCGTCCAGTAAACCAATCATTATAAATCGCCAGTTGAAAGCTCCCCGTGGGCATCGGAAACTAACAGCTCAGGCCGGCACATTCCGCATCAAGGAGGAGCCAGATGCCAACGAATTTACCGTAGAGATACAGGGTGAAGATGATCAGTTTATGGTCGTTCAGCTAGTTGACGATAATAACGAAGTTGTAATCAAGCGTGAGCCCAAGATCAATGCCAACAATTGTTTTGGCTTCGAGGACGAAGCCGATGCAGAGTACGATGAGTATGTTGAGCCCGTAGCCGAGGTGGACGCCACATCCCAGGAGTTTCTACAGCTAATGGACATGATTGAACAGGATTCGTAG
Protein Sequence: MSNRTRDSESEDLQSFLLNFHKEIEDGSVDGKDVKPPDDDAEEEEEEEQEDQDDNDDEFFIDDEGNCYIKTTAKKQQELKKKLTSQATSKAASAQEPIAIRSATRAASSSTSKGITLRPAKTKSYSSPQKTAKAINIRPAPPKRTPPKTTSTPVSMSKANLRSTDVKTSAKAVREESESMPQHSKVVIEKVEEFEELVDDPSGVDETAISIDESELTLGNDDSLESKNESDGKVYEFDDNIANMSAKSDVDFVLSGNQYKLKPVATNSEGAQKYACSHCSYTTNKKFLISRHVRTHGAERSFKCSICERGFKTNVGLINHINTHMGNKPHKCKQCDSKFTTSGELVRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHLVIHTGEKKFQCDICLSRFTQSNSLKAHKLIHSVANKPVFQCTLCPTTCGRKADLRTHMTSMHASDKPIACKRCGQQLPDRYQYKLHIKSHEGEKCYSCSYCCYRTISQRHLESHLLIHTDSKPFKCDLCSQEFRQQQLLRRHKNLMHDEGYKKPKPREKVHGCPGCARVYTHKGNLMRHMETHDDELNVREAKLRLKLGRNVRLRPDGSVVNVGSSSVVDELGISEAISFDEQFEITELEEVDEVEEEEEQPRVIVEETFTKPTSRTKEQNKTVVSKDREQSSSSKPIIINRQLKAPRGHRKLTAQAGTFRIKEEPDANEFTVEIQGEDDQFMVVQLVDDNNEVVIKREPKINANNCFGFEDEADAEYDEYVEPVAEVDATSQEFLQLMDMIEQDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598347;
90% Identity: iTF_00547529;
80% Identity: -