Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: Kr-h1
Assembly: GCA_004149445.1
Location: SCDR01001409.1:16694-22891[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0038 0.46 11.6 3.0 1 23 214 236 214 236 0.98

2 8 1.6e-06 0.0002 22.2 1.5 1 23 310 332 310 332 0.99

3 8 2e-05 0.0024 18.8 2.3 1 23 338 360 338 360 0.98

4 8 4.2e-07 5.1e-05 24.0 2.8 1 23 366 388 366 388 0.99

5 8 1.3e-06 0.00016 22.5 1.1 1 23 394 416 394 416 0.98

6 8 0.00011 0.013 16.5 1.4 1 23 422 446 422 446 0.99

7 8 0.55 66 4.8 3.7 1 23 452 474 452 474 0.94

8 8 8.5e-07 0.0001 23.1 0.6 1 23 480 502 480 502 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0038	0.46	11.6	3.0	1	23	214	236	214	236	0.98
2	8	1.6e-06	0.0002	22.2	1.5	1	23	310	332	310	332	0.99
3	8	2e-05	0.0024	18.8	2.3	1	23	338	360	338	360	0.98
4	8	4.2e-07	5.1e-05	24.0	2.8	1	23	366	388	366	388	0.99
5	8	1.3e-06	0.00016	22.5	1.1	1	23	394	416	394	416	0.98
6	8	0.00011	0.013	16.5	1.4	1	23	422	446	422	446	0.99
7	8	0.55	66	4.8	3.7	1	23	452	474	452	474	0.94
8	8	8.5e-07	0.0001	23.1	0.6	1	23	480	502	480	502	0.98

Sequence Information

Coding Sequence: ATGACCGATTTCCCAATGAACGATATCTTGAGATCGTTCAGAAAAATGCGAATGAATAAAAGCTCGGGTCAAGGCAGCCATTTGATTCCacatcataatcatcatcatcaccaccatcatcatcatccacagcagccgcagaaCTATCAACATTATCAACAGCCGACAGTGCAACAGTCCAAAGAcctaaagaaaattattaaaattatcaaaaagaacctaattaagcaaaaaattacgcATTCATCCACAACCAACATGGTCTACTATTCCGCCAACCAGCTGCTTATAAAGACGGAGCAACCCAGCCAGGCGCAGTTCTGCCTGCAGGCGCCGCTTGCCGCGACGAGCGGAGCGCCACCTAGCGGCCAGAACGAGCAGTACGAGTTGCTGCAGACgccgcagcagcgccagctgcaaatgcagcagcagcagcagcaacaacaacagcaacaatatcaaTTGaacctgcaacagcaacaacagcaacaacatgaaagtattacaacaacaacagcggcatcagcggcagcagcaacaacaacaacacagcagcGCATTAAAACAGAGCCGCCGTTGACCTTTGGCCCCTTGGCGAGCACATCGAAGCCGGCCGCCGCGGTTCGCAGCAAGCCGCAGTTCAAGTGCGAACAGTGCGGAATGACCTTTGGCAGCAAGTCGGCGCACACCTCGCACACAAAATCGCACGCAAAGAACGCGGATCTGCTGCTGGGCCTCAAGGGCAGCAcctccagcagcaacagcagcagcaacagcagctccatctccaattacaacaacaacaacgccaacgtCAACGCCAACACGCCGCCCATCGAGCTAAACGAGGCGGGACAGCCCCTGGGCGGCATTCCCAAGAGTCCGACCATCAAACCGCTGGCCAAtgtcgccgccggcgccgatCCCTATCAGTGCAACGTTTGCCACAAGACATTCGCGGTGCCCGCGCGTCTGATCCGGCATTATAGGACGCACACCGGCGAGCGTCCGTTCGAGTGCGAGTTCTGCCACAAGCTGTTCAGCGTCAAGGAGAATCTGCAGGTGCATCGGCGCATCCACACCAAGGAGCGGCCGTACAAGTGCGACGTATGCGGCCGTGCGTTCGAGCATTCCGGCAAACTGCATCGCCACATGCGCATCCATACGGGCGAACGGCCGCACAAGTGCTCCGTCTGCGCCAAGACCTTTATTCAGTCCGGCCAGCTGGTGATCCACATGCGCACCCACACCGGCGAGAAGCCGTACAAATGCCCGGAGCCCGGCTGCGGCAAAGGCTTCACCTGCTCGAAACAGCTCAAGGTGCACTCGCGCACCCACACCGGCGAGAAGCCGTATCACTGTGACATCTGCTTCCGTGACTTTGGCTACAACCACGTGCTGAAGCTGCACCGCGTCCAGCATTACGGCGCCAAGTGCTACAAGTGCACCATCTGCGACGAGACCTTCAAGAACAAAAAGGAGATGGAGGCCCACATCAAGGGCCACGCCAACGAGCTGCCCGAGGACGAAGTGGAggcggctgcagcggcagccgcgGCTGCAGCGACAGCGGTCTCCACGGTATCCACCTCCACCTCGTCCATAGCGAGCAATTCggagagcagcaacaattcgCCGCCCAGCTCGCCGCCAGCGTTGGCCAAGAAGCCACGCCAGCCACGTGGCGCCAAAGCAGCGaaggcaacagctgccgccaCATCCTCGCCACTCTCGCCCAGCTCCGTTTCGTCGGTTTACTCGCCGTTGAGCAGCCAGGCCTCGCCCCAATATCTGGCCGCATCGGCGCCAAACGAGCCGGACGGACTGAGTCGGGACAGCGGCGTCTCCAGCGCCCAGCTGGTGACCAGCTATCCGGATGAGGAGCTGCCCACGGATCTgagcatgcagcagcagcaacagcagcagcagccagcgatGGTCTATTATCAGCCCAGTTTAATGGagctgcagccacagccaaCGACAGCCGGACAGATCATTGATCCCGCGCTGCTCGAGGCGGCCAGAATAGCCCGGGGCGATCAGGACGCTGACGATGAGGACGTCAAAGCGGCCGCCTGGCAAATGGTGCAGCTGCGACGGGGTCATGCGGCGACGCcacagccccagccccagccccaaccccaaccccaaccccaagtccaaacccaaacccaacaaccacaaccacaagcacaagcacagCAGGAGCCACAGCAGCCGGCGCTGCTGGTCAGCGATCTGGCGGCCAACTACGATGACACCCACGAGGCGAACGTGCTCATCGAGCACTTCAAGCGCGGCGATCTGGCGCGTCATGGACTCCACAACGGCTATGTGCCGGTGCCCATGTACGAATCTGCCCTGCCCAATGCGGATATTGTGCGTCGCGTCGAGGCGGCCATTGGACTACGGTCCAGCACGGAATCGCCGGAGCGCAGCTCGTCGCCGGAGAGCGACTCCCTGATGATGGCCGATCGGAATGTGATGACGCTGCCGTTGCGCAAGCGCAAGCACTACATGAACGAGGGCGAGGCCAGCAGTGTGGGGGGCGGCAGCGGTGCCGCACACGGCGCCGGCGATGCTGCCTcaatagcagcagctgcagcggcggcggcggcggcagcggcaagcGGCGCAGATGGCGCCAACGCTGGCGGCGCAAAGGTGATGCGCATGAGCTCGGTTATCCAGTTTGCCAAGGCCTCGTAG
Protein Sequence: MTDFPMNDILRSFRKMRMNKSSGQGSHLIPHHNHHHHHHHHHPQQPQNYQHYQQPTVQQSKDLKKIIKIIKKNLIKQKITHSSTTNMVYYSANQLLIKTEQPSQAQFCLQAPLAATSGAPPSGQNEQYELLQTPQQRQLQMQQQQQQQQQQQYQLNLQQQQQQQHESITTTTAASAAAATTTTQQRIKTEPPLTFGPLASTSKPAAAVRSKPQFKCEQCGMTFGSKSAHTSHTKSHAKNADLLLGLKGSTSSSNSSSNSSSISNYNNNNANVNANTPPIELNEAGQPLGGIPKSPTIKPLANVAAGADPYQCNVCHKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCAKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGAKCYKCTICDETFKNKKEMEAHIKGHANELPEDEVEAAAAAAAAAATAVSTVSTSTSSIASNSESSNNSPPSSPPALAKKPRQPRGAKAAKATAAATSSPLSPSSVSSVYSPLSSQASPQYLAASAPNEPDGLSRDSGVSSAQLVTSYPDEELPTDLSMQQQQQQQQPAMVYYQPSLMELQPQPTTAGQIIDPALLEAARIARGDQDADDEDVKAAAWQMVQLRRGHAATPQPQPQPQPQPQPQVQTQTQQPQPQAQAQQEPQQPALLVSDLAANYDDTHEANVLIEHFKRGDLARHGLHNGYVPVPMYESALPNADIVRRVEAAIGLRSSTESPERSSSPESDSLMMADRNVMTLPLRKRKHYMNEGEASSVGGGSGAAHGAGDAASIAAAAAAAAAAAASGADGANAGGAKVMRMSSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00588996; iTF_00567757; iTF_00496021; iTF_00598325;
90% Identity: iTF_00567757;
80% Identity: -