Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01000616.1:25332-27237[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.099 12 7.2 0.3 1 21 285 305 285 306 0.95

2 10 2.6e-06 0.00031 21.6 1.1 1 23 314 336 314 336 0.99

3 10 0.038 4.6 8.4 0.9 1 23 339 362 339 362 0.93

4 10 1e-06 0.00012 22.8 0.8 2 23 369 390 368 390 0.98

5 10 6.3e-07 7.5e-05 23.5 1.0 1 23 396 418 396 418 0.98

6 10 1.4e-06 0.00017 22.4 2.2 1 23 424 446 424 446 0.99

7 10 0.00076 0.091 13.8 3.7 1 23 452 474 452 474 0.99

8 10 0.00081 0.098 13.7 0.3 1 23 480 502 480 502 0.98

9 10 6.1e-05 0.0073 17.2 3.6 1 23 508 530 508 530 0.99

10 10 0.00028 0.034 15.2 0.1 1 23 536 558 536 558 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.099	12	7.2	0.3	1	21	285	305	285	306	0.95
2	10	2.6e-06	0.00031	21.6	1.1	1	23	314	336	314	336	0.99
3	10	0.038	4.6	8.4	0.9	1	23	339	362	339	362	0.93
4	10	1e-06	0.00012	22.8	0.8	2	23	369	390	368	390	0.98
5	10	6.3e-07	7.5e-05	23.5	1.0	1	23	396	418	396	418	0.98
6	10	1.4e-06	0.00017	22.4	2.2	1	23	424	446	424	446	0.99
7	10	0.00076	0.091	13.8	3.7	1	23	452	474	452	474	0.99
8	10	0.00081	0.098	13.7	0.3	1	23	480	502	480	502	0.98
9	10	6.1e-05	0.0073	17.2	3.6	1	23	508	530	508	530	0.99
10	10	0.00028	0.034	15.2	0.1	1	23	536	558	536	558	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATATGTCGCACTTGTTTAAGCCTCATGGGTCCATTTCTGTCCATTTACGACGGTGAAGCCGGCAGCTGTTTGGTCGATATGCTGCGCGAGTTCACCAGGACTAAGCCGCGTCGCGAAGATAATATGCCAGCCAGGGTCTGCCTGAGCTGCATCAGCGAAATCAATCACTGCTACTCGTTCAAGCTCAAATGCGAGAACTCGAACCGCACGCTGCGTCAGCTGCTGCCCAATGCGCTGCCCGAGGAGCCCGGTCAACTGACGACAGCCAAGCCCACGGTGGCCACGGCCGAGAGATCGGTGCAAACCAATATTGTGACTACAGTCACAGCTGAGGCGCAAACGGATGTGCTGGCTACAGCAGAACCCGGCCTGGAGCAGCCAGTGCTGGCAGAGGACCCACAGGAGGAGGCTGAGGGggaggacgaggaggaggaagaaTATGACTATGAATTTACCGAAGAGCAGGAGCCCGAATTGGCACCGTCCAAGGCCAGCGCCGAGAACATAATACTGCATGTGGAAAAGGACAACATTAAGTTCGAAACGGAAATGTTGTATAACAAAACCACAGGCGAGCTGGTCGAGCAGCCGGTGGAGACCGCTGCCAAGCAGAAGCAGTACAAATATCGTCTTgtcagcaatggcaacggtgACACATACATTGCCCCAGAGCCGGCCACAACCGAGCTGCCCACACGGAAGTCCGCCGCAAAACTGTCCAAGGaagaggagcagcaacagcctgAGTCGCAGTCAAcgtccaagcagcagcagcaaccaaagcCCGGCAACTTGAATGGAACGTCCGCAGGTGAATCGGATGAGCTGAAGGCCAAGTTTCACTGTGATCGCTGTAATGCGGGCTTCGCATTAGAGAAATCTCTGATCATACATCGGCGTCAGAAGGGTTGCACCCATCGCAATTTCAAGTGCAACGAATGCGAGCGGGTGTTCGTCTCAATGGATCACTTGACCGAGCACCAGGCCACCCACGGGACGTACATCTGCCAGGAGTGCAGCTTGCGCTGCGAGTCCATGGAGCAGCTGGGGAGGCATATGGTGCAGACGCACAAGCGCAATCTGCGCAATCAGTGTAATGTGTGCCAGAAGGtGTTCACCATGTTGTCCACGCTGCGGGATCACATGCGCATCCACACCGGCGAAAAGCCGTTTGTGTGCAATGTCTGCGGCAAGGGATTCACACAGAAGGCGAATATGCGCCAACACAAGATGCGTCACTCGGATATTAAGCGCTTCAAGTGCGAGCTGTGCAATCATTCGTTTGTAACCAAAGCGGAGCTGACGTCCCATGTGCGCACCCACACGGGCGTCAAGCCGTATCAGTGTGAGGTCTGCGCCTCCAGATTCACCACCAGCTGCTCTTTGGCCAAGCACAAGCGCAAGCACACCGGCGAACGGCCCTATGCCTGTGATCTCTGCCCCATGCGCTTCACAGCGCTCAACGTCCTCAAAAATCATCGACGCACCCACACGGGCGAACGACCCTACGTCTGTCCCTTCTGCTCGAAGAGCTTTACGCAACGCGGCGACTGCCAGATGCATCAGCGCACCCATCAGGGCGATAAGATCTACATTTGTCCCGTCTGCAGCGAGGAGTTCAAAACAATGAACGATATGCGTGCGCATCTGACGATGCACGAACAGGACGACAAGCGGCTGGTGCACTTCACCCTTCTGAGCAACAAGGAGAACGGCAATGCGGCGCTGGAGGAAGCCGACGAGGAATCAGACGCAACGGACATGCTGTAG
Protein Sequence: MDVEKICRTCLSLMGPFLSIYDGEAGSCLVDMLREFTRTKPRREDNMPARVCLSCISEINHCYSFKLKCENSNRTLRQLLPNALPEEPGQLTTAKPTVATAERSVQTNIVTTVTAEAQTDVLATAEPGLEQPVLAEDPQEEAEGEDEEEEEYDYEFTEEQEPELAPSKASAENIILHVEKDNIKFETEMLYNKTTGELVEQPVETAAKQKQYKYRLVSNGNGDTYIAPEPATTELPTRKSAAKLSKEEEQQQPESQSTSKQQQQPKPGNLNGTSAGESDELKAKFHCDRCNAGFALEKSLIIHRRQKGCTHRNFKCNECERVFVSMDHLTEHQATHGTYICQECSLRCESMEQLGRHMVQTHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQKANMRQHKMRHSDIKRFKCELCNHSFVTKAELTSHVRTHTGVKPYQCEVCASRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKTMNDMRAHLTMHEQDDKRLVHFTLLSNKENGNAALEEADEESDATDML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551023;
90% Identity: iTF_00567682; iTF_00598304; iTF_00541896; iTF_00588985;
80% Identity: -