Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: -
Assembly: GCA_035044305.1
Location: JAWNMF010000125.1:5053323-5056143[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0022 0.16 12.6 5.1 1 23 686 708 686 708 0.98

2 5 1.6e-05 0.0012 19.3 0.4 2 23 721 742 721 742 0.98

3 5 0.00023 0.017 15.7 1.4 2 23 750 771 750 771 0.97

4 5 0.0007 0.052 14.2 0.9 1 23 776 801 776 801 0.92

5 5 0.086 6.4 7.6 0.1 1 23 809 833 809 833 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0022	0.16	12.6	5.1	1	23	686	708	686	708	0.98
2	5	1.6e-05	0.0012	19.3	0.4	2	23	721	742	721	742	0.98
3	5	0.00023	0.017	15.7	1.4	2	23	750	771	750	771	0.97
4	5	0.0007	0.052	14.2	0.9	1	23	776	801	776	801	0.92
5	5	0.086	6.4	7.6	0.1	1	23	809	833	809	833	0.91

Sequence Information

Coding Sequence: ATGATGGACCGCAAGAAGGTGTTGGAATTGGACAAAATCTGCCGCCTTTGCATATCGGAGCGGAAGGAAATGCGCCCGTTATTCAGCGAAAAAGTGCCCGAAATGCTAATGGACTGCACCAGCGTACGCGTAGAGCCCACCGAGGGCTGGCCGGACAAGATATGCGTGCAGTGCGTTCATGCGGTCAGCCGAAATCATGCATTCAAAACGCTCGTCGAGCGGAGCGACAAAGAATTGCGCGAATATATTCAAGGCCTCACAGTGCGCATGGTCACCGATGAATCGTTGACGCCGCAGGAGCGCAAGCAGCAAAAGCTTCTGCTGcaaaaacaactcaaacagcagcaacaacagctcgaggagcagcaacaaatattaatgcagcaacagctgctgcaacaacaacagcaacagcagcaacaacattcgCCCATTTttgtgctgcagcagccgcaacaccaacaacaacaagtgcagctCAAGCCCAAGAGTAAATTGAAGCCACTGATGCGCAAGGGCGCCGCACGTCAAACGAAAAAGCAGCAGGAGATTGTGCAACTACTGCCAGAgccagcaccaccaccgccacctcCGCTGATaacccagcagcagcagcaacaacaacaacaacaacagcagcaacaacacataCAGCAGATGCAGCTGCCAACGCTGCAACCGGCGCCAACGCAACtgatgccaacaacaacacaacagcaaatCCTACTGCCGAATGGGCAGTTTATCACCACACAGATTGTGACTCCGCAGCTGGCGCAGATAATCAGTTCGCAGGCGACaacaaatgcgaatgcgaCGCAAGCTCAATTTCTGCCACAACTCCTGCAAGCGCCCAATGGTCAAACGTTGCAAATTGTCCAGCAACCGAATGGTACACAGACGGTACAGCTTGTCCAGCTGGTGCCACAGCGCACcatggcggcggcggctaCGGCAGCAACGgtgaccacaacaacaacggcggAGCTGTGTGCGGCGAGTGGAAATGGTGGCGCCTCTTTAGCCGATGCAGATGTTCATCTGCTGGACGATGGTGAAATGGTGGACGATGAGGAGCTGGATGAGGTGTATGAACAGCTCGATGGCAAGGGTCACACATTCGAGACGATTGTGCTGGACGATGATCAGCAGCAGGATTATCTcaaggagcagcaacagcagcagcagcatcatcaccaccatcatcatcatcaggtTCTCATCGACGAGGAGTTGACGCACAGCGACATCCAGGATCAGGAGCACGACCACGAACAAGAATTGgatcaggagcaggagcatGATGGTTATTTTGATGAGCAACTGATGCAGCACGAGGATGGCAGCGGCATTGTCAAACCggaggatgaggatgaagATAATTTCATCATTGAGGAAATCCAGCTCGATGATGAGGATATGCTTGACGATGGCGAGGGCGGTGAAATGGAGGGCGATGTGGATGATATGACGCCAGTAGATGAATGCGAATATATTACGGATGACCCGGAGCACGGTGGACTCGCCGGCGATGTCGATGATGAGCTGCACTATGCGATTATGGAGCCAACCGATGGCGATGTGAGTGCCAGCGATATTGAGCAGGCCTTCATCGATGTCgatgcacagcagcaacagttgcaggagcaacagcaacaacagctgcaggagcaacagcaacagttgcaggagcagcagcaacaacaatcaatggAACTGCAGAGTTTATCGCTGGAGAATGCAGTTGTTGAGTTTAGACAGGATACTCTGACGCTGCATGTGAACAGCACGCCAAGTCCCACGCCCAGTGCTGCCAAACGAACGcgtcgcaacaacaacaacaacaaccagcaacagcaacttgtgGAACAACCCTGCAATCATCAGCACAGTCCACCCACAATTAGCAGTAAACTTGCCGCAGCCAATTCACGCCAATTGGTGCAAACTGCATCGGTgattgcagcagcaggtgcGGATGATAATTACGAGATCGATGCGAATCTTGTGACGGAATTCATAAGGCAACACACGTCACCACTCGGTTCGGGTCGCTACATCTGCCACTTGTGCAGCACGGAGTTCCGGCAGTTCAAGGGCCTGCAGAATCACATGCATTCGCACACGAATTGGATACGGGCGAATTGCAAGAAGCAGCCGCAATGCGAGATCTGTTTGAAGAGTTTCAAGGGACCCGGCATGTTGCGCATGCACATGAAGACGCACGATGCGGAGACGAGTACGCCGGTGTGCAACATTTGTAATCGCACATTCAAATCGAAGGCGATACTGTATCGGCATCGGCAGACGCATCAGCAGCGTGCGTATTGCTGTGGTGTCGCCAATTGTCGCAAGAACTTCTCGAATGCGGCGAATCTGCGCTGGCACGTCGAGCGCAAGCATCCCGAGTGTGTGGAGCCCTTCTACAAATGCGGGGAATGTTCGACGTTATACGATAATATCGACGGGCTGCAGCAGCATGTGGAGACAACGGAtcatggcagcagcagtgtgGTCAATGAACAGCTAATTGCCACTGATTCAACGAAtgtgacagcagcagcggcggcggctgcagcagctgcatttaGCGGCGCCGTTAGCATTGTTAGCAACGCCACCGATATGTCCGATATGACCAGCATGATTGCTGCCGCTCCGAATGCATTGGGCGGTGGCACTGGTGGTCACACGGGGGACACACATGCCGTTGTCGTCGGCTCCTCCGGCGAGATGTATTTTGTGACGCAGGCGTAG
Protein Sequence: MMDRKKVLELDKICRLCISERKEMRPLFSEKVPEMLMDCTSVRVEPTEGWPDKICVQCVHAVSRNHAFKTLVERSDKELREYIQGLTVRMVTDESLTPQERKQQKLLLQKQLKQQQQQLEEQQQILMQQQLLQQQQQQQQQHSPIFVLQQPQHQQQQVQLKPKSKLKPLMRKGAARQTKKQQEIVQLLPEPAPPPPPPLITQQQQQQQQQQQQQQHIQQMQLPTLQPAPTQLMPTTTQQQILLPNGQFITTQIVTPQLAQIISSQATTNANATQAQFLPQLLQAPNGQTLQIVQQPNGTQTVQLVQLVPQRTMAAAATAATVTTTTTAELCAASGNGGASLADADVHLLDDGEMVDDEELDEVYEQLDGKGHTFETIVLDDDQQQDYLKEQQQQQQHHHHHHHHQVLIDEELTHSDIQDQEHDHEQELDQEQEHDGYFDEQLMQHEDGSGIVKPEDEDEDNFIIEEIQLDDEDMLDDGEGGEMEGDVDDMTPVDECEYITDDPEHGGLAGDVDDELHYAIMEPTDGDVSASDIEQAFIDVDAQQQQLQEQQQQQLQEQQQQLQEQQQQQSMELQSLSLENAVVEFRQDTLTLHVNSTPSPTPSAAKRTRRNNNNNNQQQQLVEQPCNHQHSPPTISSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEFIRQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCEICLKSFKGPGMLRMHMKTHDAETSTPVCNICNRTFKSKAILYRHRQTHQQRAYCCGVANCRKNFSNAANLRWHVERKHPECVEPFYKCGECSTLYDNIDGLQQHVETTDHGSSSVVNEQLIATDSTNVTAAAAAAAAAAFSGAVSIVSNATDMSDMTSMIAAAPNALGGGTGGHTGDTHAVVVGSSGEMYFVTQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00576648;
90% Identity: iTF_00577350;
80% Identity: -