Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: -
Assembly: GCA_035044305.1
Location: JAWNMF010000133.1:1804248-1807200[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00091 0.068 13.8 1.2 3 23 152 172 150 172 0.96

2 7 0.0049 0.37 11.5 0.9 1 21 178 198 178 199 0.94

3 7 0.019 1.4 9.7 2.4 2 23 531 553 530 553 0.94

4 7 1.4e-05 0.0011 19.5 2.0 1 23 645 667 645 667 0.98

5 7 4.4e-05 0.0033 18.0 5.7 1 23 673 695 673 695 0.98

6 7 0.00038 0.028 15.0 2.9 1 23 701 723 701 723 0.98

7 7 0.00037 0.028 15.0 0.1 1 21 729 749 729 750 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00091	0.068	13.8	1.2	3	23	152	172	150	172	0.96
2	7	0.0049	0.37	11.5	0.9	1	21	178	198	178	199	0.94
3	7	0.019	1.4	9.7	2.4	2	23	531	553	530	553	0.94
4	7	1.4e-05	0.0011	19.5	2.0	1	23	645	667	645	667	0.98
5	7	4.4e-05	0.0033	18.0	5.7	1	23	673	695	673	695	0.98
6	7	0.00038	0.028	15.0	2.9	1	23	701	723	701	723	0.98
7	7	0.00037	0.028	15.0	0.1	1	21	729	749	729	750	0.96

Sequence Information

Coding Sequence: ATGCACGAGGAAATTGTGATTAAAACTGAGGAAATTGATATTGATGATACAAAGATAAAGCTTGAGGTCGTTGAGGATGGGCCAACATTGAAATTGTCGTGcgCTGGCACCTTTATGAAAATAATCGAGGAGCGTCCGAATATGATAACGGTGCCGGTTCACGACTGCAAATCTGAGGACGAGCTGAAATTCATTGCGAGCCTCGGCACTTTCGATCAGCAGCAAAAGTTATTTGTGACGTCAACGGCTGAGAGTGCTGCCTCTCTTGGcgcatttgcatgcaaagTGTGCAGCTTTACGTGCGAAAATGACTTATCGCATGCTTCGCATCAGAACAACCATCAGCTAAATCGCCATTTCTGTTGCCATGGCTGTGGCGAGTGGTGTAACACGCTCGAAGAAATCCAGGAGCATGAATATCGAAAGCATGCGGATGGAGTTAACAACTCCAACTGCAGGATCTGTCAGTTGGAGTGTACGGATGCAGCCAATCTGTCGAGGCACATGAGCAGTCACTTCTATGTGCGTCGTTTTGTGTGCTCCATTTGTCGCCGGCATTTTGAGACACGCCTGGAATTACAACTGCATCGGCAGAACGGCAATAAGCTGTGCGGTCAGCTCGAATATGCGGATATGCATGGAAACATCGGTCAGCTGGTGGCGATCAGTAAATTGGATACGACACTGCCAGCTGAGCGGTTCTGTGATATAGAAATTAAATCTGAGCCGATGGACGTAGAGGACCAGCTTCCAActggtattattattaaaacggAGCCACAGTCGCAAGCAGCTGAGTTAAATTCCACTGGCCACGATCACAGCCGGGCCCGAAACAGCCTAGCTGGACAATTGCGCAGCAAATTGCGCTTGCCCATAATAAAGAAACCGCCGAAAGAGGAATGTATAGTGGAGGAGAAACCAAGAGCCCCTGTGACTAAATCAAACATTGTGCCCACTGGTAAACTGATACCTTTTGCAAACTCTACAGCATCACAGAATCACTCCAACATTTTATGGCCAAAGCAATCAGACAAGCAGACCTCAAGTATTTTGAAGAACATTTccaaacccaaaacaaatgtttccGCCAACGTCGTAAAGATAATGCAAAGTAATTGCATGGTGATTAAAGTGCTGCCAAACAAAAAGGTAATAAAGCTGGCACCCACCGCAACGGGTAACACTACGAATAGCTTCAACATAGGAGggaaaataattacattgcCAAGCTCCATGTCGATAAGTTCGGGACTTCAAAGCTCGACGGCTGGCCAAACCCCATCTGCTCTTACTTCGCGACAAGCGGCCTCATTGACATTGCCCATTAATCGAAATTCTCATTTGAATGCTATTAGTTTGTTTGAGAGTTTGCCAGAGTCTCGCAAGATCATTACAGATATCCAGAATCAGATACGCAACATAGAGCAAACGCTGCCACTGCCAGGCAGTGTGCTGCAACCGAAAAACACAAGCACCAAAGTTGAGTTGCCTGCGCAGCTTCAGATGCTTCGACTGCCGCTCACCAAGGAGAGTAATCTGAAGGTACGTCAATTGCGCAACGCATATCCTGATCATCGCTTTCACTGGGAATGTCCGACCTGTGCGCGCTGTTTCGAACAATTTGCGGCATTCTGCAAACATTTGACAGTCTCGCACGACATCGCAGAGGCGAAGTTTGAGCACATGTCAGTGGAGGTCAAGTCTTATAAGAAAGGCATTTCGTTGATTTCCACAACTGTAGAAGCGACAGTTCCTGTAGTGTCAGATACAATAAATACGTCTCCATTAAATTATTCTGCTGATCCAGATCCTGTGCAGGATGCAGGGGCAGCTGCTCCAGCAACTGTGGCATCTGAAATTGCAGATCCTGAGCCAATCTTACCGACCACAGCGGCTACTAGTGTAATCCCCCAATCTTGGTATTCTCGATATAAATGCGACGATTGCTCAAAGTGCTTTACCACTATGGGTGGGCTGCGCATCCACAAGATGATTCACACCGGCGAGTTGCCACATAAATGCAACTACTGTGAGAAGCGTTTCCGCACTCCTGGCCAGGTGCGTGTCCATCATCGCAGGCACACTGGCGAGAAACCATTCAAATGCAAGGTGTGCTCACTGGATTTCACACATCGCGAAACGCTCATCTCGCATCTCTCGCGTCACATTGGCATGAAGCGCTACAAGTGCTACGGTTGTGATAAGAACTTTATTGTTGTCAGTGGATTGCGTGCCCACCGCCGTTTACGTCCTGACACGTGCGGCAAGGTCAAGTTTACAGCTCGCGCACACGGGCCGCGAGTTCGCGTAATACGCGGCGAAGTCGTCTTCGAATCCCATCCTGAGCACAATGGCTACTTGCGCAGCGAGGACCCTTTAAACATAATGTCTGAGATGATTCATGCCAAAGAACCGTCTGTGGCCAATGAGTCCAGCTAA
Protein Sequence: MHEEIVIKTEEIDIDDTKIKLEVVEDGPTLKLSCAGTFMKIIEERPNMITVPVHDCKSEDELKFIASLGTFDQQQKLFVTSTAESAASLGAFACKVCSFTCENDLSHASHQNNHQLNRHFCCHGCGEWCNTLEEIQEHEYRKHADGVNNSNCRICQLECTDAANLSRHMSSHFYVRRFVCSICRRHFETRLELQLHRQNGNKLCGQLEYADMHGNIGQLVAISKLDTTLPAERFCDIEIKSEPMDVEDQLPTGIIIKTEPQSQAAELNSTGHDHSRARNSLAGQLRSKLRLPIIKKPPKEECIVEEKPRAPVTKSNIVPTGKLIPFANSTASQNHSNILWPKQSDKQTSSILKNISKPKTNVSANVVKIMQSNCMVIKVLPNKKVIKLAPTATGNTTNSFNIGGKIITLPSSMSISSGLQSSTAGQTPSALTSRQAASLTLPINRNSHLNAISLFESLPESRKIITDIQNQIRNIEQTLPLPGSVLQPKNTSTKVELPAQLQMLRLPLTKESNLKVRQLRNAYPDHRFHWECPTCARCFEQFAAFCKHLTVSHDIAEAKFEHMSVEVKSYKKGISLISTTVEATVPVVSDTINTSPLNYSADPDPVQDAGAAAPATVASEIADPEPILPTTAATSVIPQSWYSRYKCDDCSKCFTTMGGLRIHKMIHTGELPHKCNYCEKRFRTPGQVRVHHRRHTGEKPFKCKVCSLDFTHRETLISHLSRHIGMKRYKCYGCDKNFIVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIRGEVVFESHPEHNGYLRSEDPLNIMSEMIHAKEPSVANESS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00620147;
90% Identity: iTF_00497693;
80% Identity: -