Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: Kr-h1
Assembly: GCA_035044305.1
Location: JAWNMF010000252.1:5004274-5008915[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0045 0.34 11.6 3.0 1 23 204 226 204 226 0.98

2 8 1.9e-06 0.00014 22.2 0.5 1 23 289 311 289 311 0.99

3 8 2.3e-05 0.0017 18.8 2.3 1 23 317 339 317 339 0.98

4 8 5e-07 3.7e-05 24.1 2.8 1 23 345 367 345 367 0.99

5 8 3.7e-07 2.7e-05 24.5 1.3 1 23 373 395 373 395 0.98

6 8 0.00013 0.0095 16.5 1.4 1 23 401 425 401 425 0.99

7 8 0.65 49 4.8 3.7 1 23 431 453 431 453 0.94

8 8 1e-06 7.5e-05 23.1 0.6 1 23 459 481 459 481 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0045	0.34	11.6	3.0	1	23	204	226	204	226	0.98
2	8	1.9e-06	0.00014	22.2	0.5	1	23	289	311	289	311	0.99
3	8	2.3e-05	0.0017	18.8	2.3	1	23	317	339	317	339	0.98
4	8	5e-07	3.7e-05	24.1	2.8	1	23	345	367	345	367	0.99
5	8	3.7e-07	2.7e-05	24.5	1.3	1	23	373	395	373	395	0.98
6	8	0.00013	0.0095	16.5	1.4	1	23	401	425	401	425	0.99
7	8	0.65	49	4.8	3.7	1	23	431	453	431	453	0.94
8	8	1e-06	7.5e-05	23.1	0.6	1	23	459	481	459	481	0.98

Sequence Information

Coding Sequence: atgactGAACGCACCAATGAGAAAAAGACTTGGACAGCCCAGCCGAATTGGATAAAGGATGCACTCAACAAATCCGGCACGGAATTGGTGGATATATCGAAGACCAAAACTAAAGcagcacaaaagaaaacaaatggaaatgATTCATTCACAACCAACATGGTCTACTATCCCGCTAATCAGCTGCTTATAAAGACGGAGCAACCCAGTCAGACGCAGTTCTGCCTGCAGGCGCCACTGACTCCAGCGACTGGTGGCGGCATTGGCGTTGCGCCACCTAGCGGTCAGCATGAGCACTACGAGCTGCTGCAGACGCCACAGCAgcgactgcagctgcaacagcagcagcagcaacaacaacagcaaattgtcAATTATCAACTggcactgcaacaacaacaactacaacatgATAGtattacaattacaacaacaacaacaggagcagcaacaatagcagcaacaacagcagcaacaacaacagcaacaacaacaacaacacagcagCGCATTAAAACTGAGCTGCCTTTGACGTATGTGGGCGCTGCTGCCACAACGCAGGCGGTCACAGTTGCCACGATCCGTAAGCCGAACGGCAACAAGCCGCAGTTCAAGTGCGAGCAGTGTGGCATGACCTTTGGCAGCAAGTCGGCTCACACCTCGCACACAAAATCGCATGCCAAGAATGCTGATCTCGCCATGGGTCTGAAGAGTGTCGCCAATGGTGgcgcctcctcctccacatcttccatctcctcctcctcctctgcACCTATTGAGCTGAACGAGGCCGGTCTGCCGCTGGGCATACCCAAGAGTCCGACCATCAAGCCGCTGGCCAATGTCGCCGCCGGCGCCGATCCCTATCAGTGCAATGTGTGCCAGAAGACGTTCGCGGTGCCCGCCCGATTGaTTCGCCATTATAGGACGCATACGGGGGAGCGTCCGTTCGAGTGCGAGTTCTGCCACAAGCTGTTCAGCGTCAAGGAGAATCTGCAGGTGCATCGACGCATCCACACCAAGGAGCGGCCGTACAAGTGCGACGTGTGCGGTCGGGCATTCGAGCACTCCGGCAAACTGCATCGCCATATGCGCATCCATACGGGCGAACGGCCGCACAAATGTTCCGTCTGCGAGAAGACCTTCATTCAGTCCGGCCAGCTGGTCATCCACATGCGCACGCATACCGGCGAGAAGCCCTACAAGTGCCCGGAGCCCGGTTGCGGCAAGGGATTCACGTGCTCCAAGCAGCTCAAGGTGCACTCGCGGACGCACACGGGCGAGAAACCGTACCATTGCGACATCTGCTTCCGGGACTTTGGCTACAATCACGTGCTGAAGCTGCATCGGGTGCAGCACTACGGCGCCAAGTGCTACAAGTGCACCATTTGCGACGAGACCTTCAAGAACAAGAAGGAGATGGAGGCGCACATCAAGGGCCATGCCAACGAGCTGCCCGAGGATGAAGTGGAggcggcggtggcagcagccggcgttgcaactgcaaccagtGGCGGCTCCTCCTCGTCCATGGCCAGCAATTCggagagcagcaacaattcgCCGCCTAGCTCGCCGCCGGCGGTGAAGAAACCACGTCAGCCACGTGGCTCTAAAGCTGCAACAGTTTCAGGTGCTTCTGCTGCCGGTGCTTCCACTGCGCCGCTCTCGCCCAGCTCTGCATCGTCCACATATTCGCCGGCGAGCAGCGCTCTGGCCTCACCGCCACCAGCACAATATGTAAACAATATCTCAGTCAGCGAGCCGGATGCACTGAGTCGGGACAGTGGCGTCGCCAGCGCCCAACTCCAGCCCAGCTATGCGGATGAGGAGCTGCCCACGGATCTGAGCATGCAACAGCCGCCGACGCAGTCGCCCATGATCTACTATCAGTCACAGTCCAGTTTAGTGGAGCTGCCGGCAAGCACAAGCACGACCAATCCTGCAGTTCCGCCCACTCCTGGCCTCACCATCAATCCCGCGCTGCTCGAGGCGGCCAGTTTGGCGCGACGCGACAACAGCGAGGACAACGACGAGGATGTTCAGGCGGCGGCCTGGCAAATGATGCAACTGCGACGTGGTCATGCAGCCACGCCCATAGCCCAGCCTACGCCCACGCCTATGTCCACTGCAACACCGCCGCCAACCCAAAGCCAGCCCACGTTGCACGTCAGCGATCTGGCGGCCAACTATGACGACACGCACGAGGCGAACGTGCTCATCGAACACTTCAAGCGCGGCGATCTGGCGAGGCATGGACTCCACAAGGGCTATGCACCGGTGCCCAAATATGaATCTGCCCTGCCCAATCCGGATATTGTGCGTCGCGTCGAGGCTGCGATCGGCCTGCGCTCCAGCACGGAGTCGCCGGAGCGCAGCTCGTCGCCGGAGAGCGATTCACTGATGATGGCCGATCGGAATGTGATGACGCTGCCGCTGCGCAAGCGCAAGCATTATATGAACGAGGGCGAATCCAGCAGTGGAggcggctgcagcagcggcggcggcggtggtggtggtggtggcaacaacaatgcaacagGTGCTAACGATGGCGCCACAACGAGTGGCATAACGGATGCGGCGAACAATGCCGCCGGCTCCAAGGTGATGCGCTTGAACTCTGTCATCCAGTTTGCCAAGGCCTCGTAG
Protein Sequence: MTERTNEKKTWTAQPNWIKDALNKSGTELVDISKTKTKAAQKKTNGNDSFTTNMVYYPANQLLIKTEQPSQTQFCLQAPLTPATGGGIGVAPPSGQHEHYELLQTPQQRLQLQQQQQQQQQQIVNYQLALQQQQLQHDSITITTTTTGAATIAATTAATTTATTTTTQQRIKTELPLTYVGAAATTQAVTVATIRKPNGNKPQFKCEQCGMTFGSKSAHTSHTKSHAKNADLAMGLKSVANGGASSSTSSISSSSSAPIELNEAGLPLGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGAKCYKCTICDETFKNKKEMEAHIKGHANELPEDEVEAAVAAAGVATATSGGSSSSMASNSESSNNSPPSSPPAVKKPRQPRGSKAATVSGASAAGASTAPLSPSSASSTYSPASSALASPPPAQYVNNISVSEPDALSRDSGVASAQLQPSYADEELPTDLSMQQPPTQSPMIYYQSQSSLVELPASTSTTNPAVPPTPGLTINPALLEAASLARRDNSEDNDEDVQAAAWQMMQLRRGHAATPIAQPTPTPMSTATPPPTQSQPTLHVSDLAANYDDTHEANVLIEHFKRGDLARHGLHKGYAPVPKYESALPNPDIVRRVEAAIGLRSSTESPERSSSPESDSLMMADRNVMTLPLRKRKHYMNEGESSSGGGCSSGGGGGGGGGNNNATGANDGATTSGITDAANNAAGSKVMRLNSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508507;
90% Identity: iTF_00528218;
80% Identity: -