Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: Znf574
Assembly: GCA_035044305.1
Location: JAWNMF010000166.1:1870948-1873218[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.036 2.7 8.8 0.4 2 23 338 360 337 360 0.96

2 10 3.3 2.4e+02 2.6 0.2 6 23 370 387 370 387 0.97

3 10 3.3e-05 0.0025 18.4 0.4 1 23 393 415 393 415 0.98

4 10 1.1e-05 0.00083 19.8 0.3 1 23 428 451 428 451 0.97

5 10 0.00013 0.0094 16.5 1.2 1 23 459 482 459 482 0.97

6 10 2e-05 0.0015 19.0 1.1 3 23 490 511 488 511 0.92

7 10 0.0011 0.08 13.6 0.5 2 23 523 545 522 545 0.97

8 10 4e-05 0.003 18.1 3.6 1 23 552 575 552 575 0.93

9 10 2.6e-06 0.00019 21.9 1.2 1 23 581 603 581 603 0.98

10 10 6.1e-05 0.0046 17.5 1.4 1 23 609 632 609 632 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.036	2.7	8.8	0.4	2	23	338	360	337	360	0.96
2	10	3.3	2.4e+02	2.6	0.2	6	23	370	387	370	387	0.97
3	10	3.3e-05	0.0025	18.4	0.4	1	23	393	415	393	415	0.98
4	10	1.1e-05	0.00083	19.8	0.3	1	23	428	451	428	451	0.97
5	10	0.00013	0.0094	16.5	1.2	1	23	459	482	459	482	0.97
6	10	2e-05	0.0015	19.0	1.1	3	23	490	511	488	511	0.92
7	10	0.0011	0.08	13.6	0.5	2	23	523	545	522	545	0.97
8	10	4e-05	0.003	18.1	3.6	1	23	552	575	552	575	0.93
9	10	2.6e-06	0.00019	21.9	1.2	1	23	581	603	581	603	0.98
10	10	6.1e-05	0.0046	17.5	1.4	1	23	609	632	609	632	0.97

Sequence Information

Coding Sequence: ATGGCAGCCTGTGTGCTATGTTTCGACTGCTGCAAGACCGGCGAGTCGTACAAGATATTTTCCGAGGCCGGACTGCGgctcaaaatttgcaaaacaataaacaaacatttttggctggagTTGAGCAGCGCAGCGGGAGGCGAACGCGAGGAAATTTGCCACCAGTGCTGGCAGGTCGTGAGCaactttaacaaattatacGAGCGCGTCTACAACTTGCACCAGGAGCGCCTCTGTGATGTGAAGAACGTGACGATTGAGTTCTGTGACGAAGCGGAGGCAGCAAATCCTCTAGCCTTTGGCGGTGAGTTGGATGCACTGGCCGAGGATTTCTTTCCGTCCGGCGATGTCAAGGTGGAGGTGAACGAACTGGAACCACTGCCAAAGCTCGAAATGCTCGATGAACCAGTGGTCGAAGAGCAGAGCAGGGCTTCCAAACGTACCAGTGCCGAGCGTTCAGCTACTAAGAGGCGCATCAAAAACGAGCAGCTTACCATCTCCAGTGACTCGGATGGGGACATTCCCCTAGCCGAGTTCCTCGATctaaaaacaactgcaaagccagcagcagcagcagcatcgccGCTTATTGGAAGACAGTTGCGAAGAAGCACTCGACGTGGTCGCCGAGAGAAAACCCCATCGGAATCGCCTGCAATCAGCCTGAAAAAGGAATCGGAATCTGATGATGCGGACcctgatggtgatgatgataataatgataatgatcaGGATATGGACTTTGTGGCCGCAGAAGCAGTGCTGGGCACTGAGGACAGTGCTAGTTCCAGCGAGAGCAGTGACAGCGACTCTGGCGACAGTCTGCCCGATGTTGAACCGGAGGAGCGCTATGCGGAGATACCCAAACGGGTTGTAGTCAAGCCCAAAAAGTATCGGAAGCGTCCGAAGCCGCTGGTGGCGCCGGTGCGCATGAGTCGCGATGATCTCGCCAAGCGGCGGGCGCAGCAAAAGAAATACGATGAGattatatttgagtttttcaaGAAGCTGCCATGTCACGTGTGCAATCTGTTGGTGCCCAATTTCGGAGACATGCGTCGCCATCTGCGTATGTCTCACAACATCGAGAGTGGCTTCATTGCCTGCTGTGGTCGCAAGTTTCACATACGCAGGGGTCTGGCTGAGCATGTACTGGTCCACAATAACCCGGAGCACTTTATGTGCACTTCGTGCGGTCGCGTCTTTCAGGACTCCAAAACGCTGGAGGCGCACGAACAAACGCACACGAATCCCCTGGCGGATGCGAAGGATAAACGCATTTATCCGTGCGACAAATGTCCGAAGACCTTCACCACAAAGGCAGCCGTCGAGTATCACATCATGTCTAAGCATGTGCCCAAGTCGGACTTTAAATACACCTGCCCCGAGTGCAATAAGAAACTGCCCACAGAGCGGAAGCTGAAGGAGCATCGACGATATATGCACGATCCAGAGACGGCAATAATTTGCGACAAGTGCGGCAAAACGCTGCGTACCCAGGCCAATCTTAAGAAACACCACGAACTTGAGCATTCCGATGAGCCACGCCCCAAACCGGATCCCGTGCAGTGCGAGATATGCGGCACCTGGTTGCGCCATTTATCCGGCCTCAAGCAGCACATGAAAACGGTGCACGAACCGCCGTGTGGCGAGCATCGCTGTCCCATCTGCGACAAGACATCGACTAACTCCCGAGCACTCAAGCGGCACATTTACCACAATCATCAGTGCGAGAGAAAGTTCCGCTGCACCATGTGCGAGAAGGCCTTCAAGAGGCCACAGGATTTGAGAGAGCACACATCGACGCACACGGGCGAGGTGTTGTACACCTGTCCCAACTGCCCGCAGACGTTCTTCTCGAATGCCAACATGTACAAGCATCGCCAGCGATTGCATCGCGCCGAATGGGAGGCGGATCGTAAGAAACCACTACCACCCAACATAATGCAGCAGGCAGCCATGAAAAAGCGACAGGGCAGCAAGGCTGCCGCTCCCACGCTGTTCCTCCAATCCGCAGAGCCCTCAACGGCACCAGCTGCCCAGAAGCCGGAatcgcaacagcaaccacaacaacaacaacaacaacaactgcattag
Protein Sequence: MAACVLCFDCCKTGESYKIFSEAGLRLKICKTINKHFWLELSSAAGGEREEICHQCWQVVSNFNKLYERVYNLHQERLCDVKNVTIEFCDEAEAANPLAFGGELDALAEDFFPSGDVKVEVNELEPLPKLEMLDEPVVEEQSRASKRTSAERSATKRRIKNEQLTISSDSDGDIPLAEFLDLKTTAKPAAAAASPLIGRQLRRSTRRGRREKTPSESPAISLKKESESDDADPDGDDDNNDNDQDMDFVAAEAVLGTEDSASSSESSDSDSGDSLPDVEPEERYAEIPKRVVVKPKKYRKRPKPLVAPVRMSRDDLAKRRAQQKKYDEIIFEFFKKLPCHVCNLLVPNFGDMRRHLRMSHNIESGFIACCGRKFHIRRGLAEHVLVHNNPEHFMCTSCGRVFQDSKTLEAHEQTHTNPLADAKDKRIYPCDKCPKTFTTKAAVEYHIMSKHVPKSDFKYTCPECNKKLPTERKLKEHRRYMHDPETAIICDKCGKTLRTQANLKKHHELEHSDEPRPKPDPVQCEICGTWLRHLSGLKQHMKTVHEPPCGEHRCPICDKTSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAAMKKRQGSKAAAPTLFLQSAEPSTAPAAQKPESQQQPQQQQQQQLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00616353;
80% Identity: -