Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: -
Assembly: GCA_035044305.1
Location: JAWNMF010000240.1:4950973-4955507[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00053 0.039 14.6 0.9 1 23 213 235 213 235 0.97

2 26 0.00062 0.046 14.3 2.8 2 23 242 263 241 263 0.97

3 26 0.016 1.2 9.9 0.8 2 23 294 315 293 315 0.96

4 26 0.0065 0.48 11.1 2.4 1 23 390 413 390 413 0.94

5 26 0.2 15 6.4 0.6 2 22 423 443 423 443 0.96

6 26 3 2.2e+02 2.7 0.4 1 20 452 471 452 473 0.91

7 26 1 76 4.2 0.6 2 23 499 520 498 520 0.96

8 26 0.012 0.89 10.3 0.7 1 23 594 617 594 617 0.96

9 26 0.0089 0.67 10.7 0.1 1 22 626 647 626 647 0.95

10 26 0.0032 0.24 12.1 4.3 1 23 656 679 656 679 0.97

11 26 6.5e-05 0.0049 17.4 0.4 2 23 693 714 692 714 0.97

12 26 2.1e-05 0.0016 19.0 5.4 1 23 720 742 720 742 0.98

13 26 0.14 10 6.9 1.3 1 23 881 904 881 904 0.95

14 26 0.028 2.1 9.1 2.2 1 22 911 932 911 932 0.95

15 26 0.41 30 5.5 0.4 1 20 941 960 941 964 0.86

16 26 5.9e-05 0.0044 17.6 1.6 1 23 988 1010 988 1010 0.97

17 26 0.00016 0.012 16.2 1.1 1 23 1017 1039 1017 1039 0.98

18 26 0.12 9.1 7.1 0.0 2 21 1066 1085 1065 1086 0.94

19 26 0.039 2.9 8.7 4.0 1 23 1131 1154 1131 1154 0.96

20 26 0.0067 0.5 11.1 1.5 1 23 1191 1214 1191 1214 0.96

21 26 0.014 1.1 10.1 3.1 1 23 1241 1264 1241 1264 0.97

22 26 1.4e-05 0.001 19.6 0.1 2 23 1285 1306 1284 1306 0.95

23 26 4.6e-05 0.0034 17.9 2.9 1 23 1312 1334 1312 1334 0.99

24 26 4.2e-06 0.00031 21.2 2.3 1 23 1340 1362 1340 1362 0.97

25 26 2.9e-07 2.1e-05 24.8 2.6 1 23 1368 1390 1368 1390 0.99

26 26 0.0005 0.037 14.6 0.3 1 22 1396 1417 1396 1420 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00053	0.039	14.6	0.9	1	23	213	235	213	235	0.97
2	26	0.00062	0.046	14.3	2.8	2	23	242	263	241	263	0.97
3	26	0.016	1.2	9.9	0.8	2	23	294	315	293	315	0.96
4	26	0.0065	0.48	11.1	2.4	1	23	390	413	390	413	0.94
5	26	0.2	15	6.4	0.6	2	22	423	443	423	443	0.96
6	26	3	2.2e+02	2.7	0.4	1	20	452	471	452	473	0.91
7	26	1	76	4.2	0.6	2	23	499	520	498	520	0.96
8	26	0.012	0.89	10.3	0.7	1	23	594	617	594	617	0.96
9	26	0.0089	0.67	10.7	0.1	1	22	626	647	626	647	0.95
10	26	0.0032	0.24	12.1	4.3	1	23	656	679	656	679	0.97
11	26	6.5e-05	0.0049	17.4	0.4	2	23	693	714	692	714	0.97
12	26	2.1e-05	0.0016	19.0	5.4	1	23	720	742	720	742	0.98
13	26	0.14	10	6.9	1.3	1	23	881	904	881	904	0.95
14	26	0.028	2.1	9.1	2.2	1	22	911	932	911	932	0.95
15	26	0.41	30	5.5	0.4	1	20	941	960	941	964	0.86
16	26	5.9e-05	0.0044	17.6	1.6	1	23	988	1010	988	1010	0.97
17	26	0.00016	0.012	16.2	1.1	1	23	1017	1039	1017	1039	0.98
18	26	0.12	9.1	7.1	0.0	2	21	1066	1085	1065	1086	0.94
19	26	0.039	2.9	8.7	4.0	1	23	1131	1154	1131	1154	0.96
20	26	0.0067	0.5	11.1	1.5	1	23	1191	1214	1191	1214	0.96
21	26	0.014	1.1	10.1	3.1	1	23	1241	1264	1241	1264	0.97
22	26	1.4e-05	0.001	19.6	0.1	2	23	1285	1306	1284	1306	0.95
23	26	4.6e-05	0.0034	17.9	2.9	1	23	1312	1334	1312	1334	0.99
24	26	4.2e-06	0.00031	21.2	2.3	1	23	1340	1362	1340	1362	0.97
25	26	2.9e-07	2.1e-05	24.8	2.6	1	23	1368	1390	1368	1390	0.99
26	26	0.0005	0.037	14.6	0.3	1	22	1396	1417	1396	1420	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATGTTTGTCGCACGTGTGCGTTGCAAGATGACAACTTGTTGGCGCTGGCAACGCGTAGTGAGAAATACGCAAAGAAAAGTATCTGCGAAATGCTGCACGAATTAACACAAAACgatCCACTGCTGGAGCATACAGATGATAAGCTACCGCAGCATTTGTGCGGTCAGTGCTTGAGCCAGCTGGAAGCAGCTTATGCATTTGTGCTGCAAGCCCGCGAGGCGCAggagcaactgttgctgcagctaCGCAAAGGATTGCAAACACAGTGCCTGGACGAAACACCTATCGACATAAGCATAGAACTCATCAAAATCGAAACAGACATTGACCTAGCTGCGTACACGGCTGACGCAGTTGATGCTGAGTTTGAGGAGGAGCGGGAGAAGCAGGTTGTCTTAAAATGTCTGCCGGAAACTGATAGCGATAGTCAGGATAATGTGAAGGACCATGACGTTAAGGTCCAAACCCTGCAACTGCGGCGCAGTGCTCGGCGAGCCAAACTGAGCACAGACAGCGAAAATGAGTCAATCTCTGAGCAGATGCAACCGTTGCCTGTTAAACGTGGACGCGGTCGTCCCCGACGTGTGGCCAAGAGGGAGACAACCACCAACGAGGATGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACTTTCTCCTGGTATCGCGACATGCAGCGCCATGCACGCATCCACTTCGAGCAGGCGGGCATTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGACAAGTACATGACCCATCTGCGATCACACACAAAGCACGTGGCCACAGACAGACTGCAACGGAGCAGCGAGTGGCGCTACGCGGAGCGTCTATACAGCTCCGGCAGATTAATGCGTGTGGAGTGCAAACTGTGCGGCATGAGTTGCCAGCGCATTCGGGAGTTGCGCGACCACCTGGCGAGTCATGTTCACATTGAGACATTGTGGAATCTCAGCCTGGACAACGATGTCATTCGGGAACAGTTTGGCAGCCAATCGGATTTGCAGCAAATCAAGGAACAGGTCTGCACGCAAATTGCCAAAGGTCGTGAACAACTGGAGAATTACGGCGCCGTGGTGAATGCCTACGGTTATGAGCTGTGCCTCAGCGACtcggatgaggaggaggatgaggagctGGCTGGAAAATATCAGTGTCTGCGCTGCAATGTCAACTTTGCACGCAAGCATCAATTCGTGCGTCACACGCTCGAGGAGCACACGGACAGAAGTGAAACCCCTTTGGAACGCTGCAATATCTGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAGCAGCATCAACGCACGCAATGCCTCAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAGCATGCATGCAGCTGGCTGCAACATGATCTGCAGCAGGAACTGCAGCACCGGcatcaggagcagcagcaggcacctCATCGCCAGATCCAGTGTTGCCTGTGCAATGAACGACCCAGCAGCATGGCTGCCCTACGCTCTCATTTACTCACTCATCGCGATGGACACACGGACATCGATCCGCATCAGCAGTCTGCCTTCTTTCGCACCTATTACCAGGATGACGGCGTCAGCAGCCTGTCGGAGATCAGGGCACGCATCGCTGGCGACTTTGAGGCGCAGCTTTATGGAAGATATTTCAATGCGTGTACGGACAGCGGACAGGAACTGGACTTCAACGACTCCGACATGGAGTGGAGCGATGCGCCCGCTCTGCATAGCTGTGCCGTGTGTGGCGAGAGTAGAATCCGCCTCAATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATTGAGCTGGCGGACAGACTGCCTCACGTCTGTTCAGATTGTGGATTGGGCTATGTGGCCGagtcgctgctgcagcagcatcgtCGTCGCATCTGCGCCAAGCTGCATGCCAAGTACCAGTGTCCACATTGCAGTCAGCGGTTCTATTGGCACTCCAACTACGAGCGGCACATTCAGGTGCAACATCCTGCGGAGAGGCAGCAGGGGCAGGAGAAGAGCAAGCTTCAGTGCAGCGAGTGCGATAAGGTGTTCATCTGGCCTAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGCGTCCACTGCGATCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCATATGCGGATGCACGGCGAGCTGCCGACGTCGTCTCTCGgtgagcagctgcagcgcatGCCGACGGTCTTGAGCCAGCTGTGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCAGCACACGAAGATCTCCGATTTGCGAACGCATTTGACTAGCCATCAGTTGAGACTGTGTTTGGCCGAGGAGCGAGGCATCGCAAACATTTGTCGTGCTCTCTATCCGGAGCTGAACACGCCATTGAATCAGCAGGCATTGATCAAGCGCATCCAGCGGGATTTGGGCAAtgaactggagctggagagATTTGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGATTCGGATTGTGCAGCAGAAACCGAACGGAGTTGCATGGAACGCGGTTACAGCTGTGAACTGTGCCAGGTGCAGGTGATGCGCAAACATCAGCTCTATGCCCACCAGCTGGAGAAGCACACGTGGCACCAGACGACGCACGTCTGCAGCCACTGCCAGGCGAGATTCGTGAATGAGCAGCTGCTGGACCATCACTATCGCACTCTCTGCCGCAATGCCCAGCGGCGTTTCCTGTGTCGCAAGTGTCCGTTGCGCTTTCGATGGCGCGATAATCTCAAGCTGCACAATGGTGTGGCGCATCAGGAGCGAGGGAATGTGGAACAGCACTCCAATGTGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTATGACTGTGTCGAGTGCAAGCGTagcttcaaaatgcaaaaggatCTCACACGGCACACCTTGATGCATGCCCAGGAATCGAGCATCTATCGGTGTCGCTGGTGCGCTCGACGCTTCTATCGCGAGTCGAATCTGCTGCAGCACATCGAGCGCCATGGCATCAGCGCCGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGTCGTCATCCACACGGCCCGAAGTGCATCAAGTGTCGCGTGTGTGAATTATCCTTTGGCAGCATTGCGGCACTGCGCTCGCATCTGCAATCGTCGCCAGTTGGCACTCATCATCCGATTGAGTCCATGGCCAACTATTCGATCACCAATCAGCTGGGTTACGAGCTGCACCTGGACGACTCAGAAACGGATGAGGAAGCCAAGCCGGTGGGCACCCCGGCGCATTACACGTGCGGCATGTGCCAGCTGCGTTGTGTGCGCAAGTTTGagctgcatcagcatcagcaggcCATGCATCGTCTGGAGCGCATCGCCGATGGCTGCGATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTCAAGTGCTCTAAATGCAGCTACAAGTTTATGTGGCAATCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAGGAGTTGACTACAAAAACATCAATGCCCAAGGCCGTGCCCGACATTGCCAACGCCGAGTGCCACATCTTCCAATGTGGTCAGTGTCCCAGTAAATACAATCGCAAGGATCGCCTCACCGCTCATGTAAAAAAGTGTCACACAGCTGGCTCAACTGCGTCAACAAAAGCGCCAGCGGTTGCCAAGCAGCAGAAAAGTTTCCTGTGCGCATTCTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATACGTCGGCACACCGGCGAGAAGCCGTTTAAGTGTGATTACTGCGACATGGCTTTTCCGCGCTCCTCCGATCTCCAGTGTCATCGACGCACTCACACCGGCGAACGGCCACACATCTGCACCGTCTGCAAGAAGGGATTCGCTCGCTCCTacaagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACACTCCACATCCGGCGCCACACGGGCGAGCGACCTTATCAGTGCAATACGTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGAATGCAGAATGGCCACTATGAGACGGAAGTGGGTCAATCGAAAGTTGACTAA
Protein Sequence: MLPTNVCRTCALQDDNLLALATRSEKYAKKSICEMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVLQAREAQEQLLLQLRKGLQTQCLDETPIDISIELIKIETDIDLAAYTADAVDAEFEEEREKQVVLKCLPETDSDSQDNVKDHDVKVQTLQLRRSARRAKLSTDSENESISEQMQPLPVKRGRGRPRRVAKRETTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGIVCEHCGKKFLRKDKYMTHLRSHTKHVATDRLQRSSEWRYAERLYSSGRLMRVECKLCGMSCQRIRELRDHLASHVHIETLWNLSLDNDVIREQFGSQSDLQQIKEQVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEDEELAGKYQCLRCNVNFARKHQFVRHTLEEHTDRSETPLERCNICQIGFVCAKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACSWLQHDLQQELQHRHQEQQQAPHRQIQCCLCNERPSSMAALRSHLLTHRDGHTDIDPHQQSAFFRTYYQDDGVSSLSEIRARIAGDFEAQLYGRYFNACTDSGQELDFNDSDMEWSDAPALHSCAVCGESRIRLNQLLQHQQSQHIELADRLPHVCSDCGLGYVAESLLQQHRRRICAKLHAKYQCPHCSQRFYWHSNYERHIQVQHPAERQQGQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECVHCDRKFHRKDGLKSHMRMHGELPTSSLGEQLQRMPTVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLRLCLAEERGIANICRALYPELNTPLNQQALIKRIQRDLGNELELERFVSITNEAGIELSLDSSETDTDSDCAAETERSCMERGYSCELCQVQVMRKHQLYAHQLEKHTWHQTTHVCSHCQARFVNEQLLDHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNGVAHQERGNVEQHSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRESNLLQHIERHGISADQLPYAEALLNASRHPHGPKCIKCRVCELSFGSIAALRSHLQSSPVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPVGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQSNLVQHIQLQHPSSEELTTKTSMPKAVPDIANAECHIFQCGQCPSKYNRKDRLTAHVKKCHTAGSTASTKAPAVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQNGHYETEVGQSKVD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -