Basic Information

Insect: Drosophila nigricruria
Gene Symbol: zld
Assembly: GCA_037075265.1
Location: JBAMCI010000107.1:13364671-13369587[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.24 18 6.2 0.1 2 23 285 307 284 307 0.93

2 6 0.0045 0.32 11.7 2.9 1 23 546 570 546 570 0.92

3 6 0.0073 0.52 11.0 4.0 2 23 1403 1425 1402 1425 0.95

4 6 0.49 35 5.2 3.4 1 22 1431 1452 1431 1453 0.75

5 6 0.0016 0.12 13.1 4.4 1 23 1460 1483 1460 1483 0.92

6 6 3.8e-05 0.0028 18.2 6.6 1 23 1489 1511 1489 1511 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.24	18	6.2	0.1	2	23	285	307	284	307	0.93
2	6	0.0045	0.32	11.7	2.9	1	23	546	570	546	570	0.92
3	6	0.0073	0.52	11.0	4.0	2	23	1403	1425	1402	1425	0.95
4	6	0.49	35	5.2	3.4	1	22	1431	1452	1431	1453	0.75
5	6	0.0016	0.12	13.1	4.4	1	23	1460	1483	1460	1483	0.92
6	6	3.8e-05	0.0028	18.2	6.6	1	23	1489	1511	1489	1511	0.97

Sequence Information

Coding Sequence: ATGGCGAGCATAAAAAGTGAAATGCCGCCACTGCACGCGGCAGAGGCGCtcgctgccagcagcagcagcagcagcagtagcggcCCAACTGatagcggcggcggcggcacagcagcaactgcagcagcagccgcagcagcaacaactgcagcagcagcagcaacaacaactgcatcggcagcaactgttgctggtgGCAGTGCGCCAGCAACGCCGAATGCGAATGCAACAATCAGCGCCGCCGCCGACTCGAGCGATAATCAGCCAGGTACGCCGCAACCAACAACACAGCAACAATCGCTGATGACTGTCgaagcacagcagcaacagcaacaacaacagcagcagcaagcatcGGGCATTACGCATCAGCCATATGCAACGCATCACATGTACGCAGCAGCCCAACAGCAACCACCTCAACAGCAGCTCTACGGCGGACTCTATGCCAGCgacatgcaacagcaacaacagcagcagcagcagagctaCGCGGCCAGCAGCTACATCAACAGCTACGAGCAATTctatcagcaacaacagcagcagcagcagcagagcgcAGCTGACTATGGCGGCGCCTATGTGGACTACAGTAAGGCCTCGGCAGTGCGCTATCATCCGTATTTGCAGCAGCCAACGTCAGTGCTGCCCACGGCTGTGgcggcagcaactgttgctgccgtcGAAGATGCCACTggaacagcagcggcagcagtcacgacaacagcagcagcaagtgtTGCTGCTATGAGTCCGCGTgtcgtcagcagcagcagccccacCTCCACCTCATCGCATCTGCAATTGAgcagtgccacgcccagttCGCCGGGAGGCGGCTGCAAGTTGCAGTGCAAGAAGTGCGGCATCTTGAACACAAACGAATCGGAATTGCAGGAACATATTGCCAACGTGCACGGAGAATCGCCATACGGGAGCAGCGGCTACGCCAGCTCGCCCTACATCAAGGAGGAGATGCCAATGCCGACGCCGACAGCAGTGGccgcggcagcagcagcagcggcggcagccaGCGGTGAATTGCTCGACTTGGACTCACAGAAGATGGTCTATCatcagcaactgttgcagcagcagcagcaacaacaccaccaccatcaacagcaacagcagcagcagcatcaacagctgcATCAACACGACGCTGTTGTTGCCGGCCTGCCCTTGGCATTGCCCGATCCATTGCACTCGATGCAGTCGATGCAGCAACGCGCGCTGCACAGCTGGGAGCAACAAGCGACGCCCACCGAGGGATTGCCGGCGTATATGCAACCGCTGCTGGAGAAATCGCCGCACTATTACGGCTCGCCCAAGCAGTCGCCGTATCATCCGTCGACGGTGGTGAAGCAGGAGTATGCCTTGATCAAATCGGAATATGCCGATTCGCAGCATTATGTGGACAAGTCCTTCGATCCGACGGCAGCGGAAGTGACCACCAGTCCGGCGGAGTTTCCCAGCACCACGACTACAGATGGCAACGCCGTAGGTGGCAACGCTGGCACAGCATATCGCGGCTTCGAGCCGCCCAGCTCTAGCTCGGTGCTGCCCGCCAATAGCCTAACAGCCAAGGCCGCCACCTGGAAGTCGAACGAGGCGCGTCGCCCCAAGACCTACAACTGCACCGCGTGCAACAAGTGGTTCACCAGCTCAGGGCATCTGAAGCGCCACTACAATACGACGCTGCACAAGAATGCGGTGAAGTCGAGCGGCCAGCCGGATCCGGCAACGCTGCCCATCTCTGCCCATCATCATCCCGCACGTGATCCCGTCACGAAGACCAGTCGACGTGGCAatgcggcagcagctgcagcagcagcagcggcggcggcagcagcagcagctgcggctgccacACAGGAACCGCCAGCTGTGGAGCCGCCCAGAAGTCCGCCGGACTACGGGGGAGGTGGCGGCGGTGTTTGTGGAGCGACGGGCGTGCAGGTGGGCGCCGCCATGTCGCAGTACTCGGCCTCGCCGTCGCCCAccgctcagcagcagcagcaacaattgatTGCCAGCAATGGTTATGCCaatggccacgcccactatCATGGCCACTACAAcatccagcagcagcagcagcaacaagtgcAATCGACGACAAACGCTTCACCACAGCATgctaatagcaacaacaacagcagcagcagcaacagcagcagcagcaacaacaacaacaattccgTTTTGAACGGTCACCCAAACGGGCTAGCAGGTCCCTCCGCcccaatcaacaacaacaacaacaacaacacacaaatgCCGTCCTCCCAAATGAGGGGCCtgctgaacaacaacaacaacaacaacaacaaaataacaacaatcaacaacaacacaacaacaacaacaatagccacAACTATAAAAGTCGAGCAAATGGAGGACAGCAGCAACTCAGCAATGGTCATGGAtcaggagcaggaggaggagcagcagcagcagcagcagcaacaacagcagttggaggagcagcaacagcagcaacacgtCTTGCTGCAACATCACCCACTGGAGCAACAGGAGCAGGTCAGCTATCTGTTGTCGCGGCCCtatcacagcagcaacagcaacagcagcaccaccatcaccaccaccagcaccaacatcagcagcagcaacagcaacaacaacagcagcagcagcaacagcaactcgcCGCCTATTATttaccaccaccaccagcagcaacaactgccgccgcagcagcagcagctgcagccgctgcagcagcagcagcaactggaacaggagcagcaacaccaaTCGCACCACCACCAACTGTTGCAGGCAATGGATTTCTCGCGCAcccagccgctgctgccgccgccgcctatGGCAGCGCTGCTGCCGCCTATAACAATGGACTACAACATGCTGGCTTTGgatatgcagcagcagcacagcaatatgctgcagtgcagcagcatcagcacgCCGCAGCAGCCGTTGCTGCCGGTCACTATTACCACCACGCCCATCCACACGCCCATCCCCATGCACACCCAcacgcccatgcccatgcccatggcCATCCACACGCCcaccacccacacccacacgcacATCAATATGGACATGGAATGCACCactatgcagcagcagcagccgcagcagcactACCTGGCACCACAGCCGCTGTCgccgctgccgcagccgctgcagccgcaacaactgttgctggtggacagcaacagcagcagcagtcacagCAGCAGTACGGCCAGCAGCCATAcgcccaacagcagcagcagcagcaaccacaacagcagcaacaacatcagcagcacagcagcaacggcgGTGGTGGGGGCACaaacagcagtagcagcagcaacatcatcgccaccgccgccacacatcatcaccagcagcagcagcaacatcatcagcagcagcagcaacatctccaacaacagcagcagcaacatctccagcagcagcaacagcagcaacaacatcctGCCATGCTATCAGCAACTGCCGCCGGTGCTGGAGCACACAATGAGCTATCACACTATTATTGGTAATGAGCCGGGCCACTACGACACCTACACGACCAGCGACGGTCATCAGATACTGCAGCTGATGCCGGCTGCCTCGCTCTTTGCGCCCTATGCGCCGCTGTCGCCCTATTCGGTGGCTGCGCAACGCTCGCCGCAGGAGGGAGACTTGCCGCCAGTGCATACGCTAACAAATGCCTTGCAGGCGCAGCAGGaggcgcaacagcagcaacaacaacagcagcagcaacatcagcagcataCGACCTTAACGCTgttggccacgcccacgccgtATTCGCCCACAGTGAGCAGCTCGCGTGCAACGCCAGCTTTGGAGCTGGACATGGTGTCGCTCatagcacagcagcagcagcacgaatACGAGCAATATCAGTTGCAGCAGCtcgaacaacagcagcaacatattgagcaacagcaacatattgagcagcagcagcagcagcaacagcaactcgagcagcagcagcagcagcaacttgagcagctgcaaatgcaacaaacTGTTGCCGTTTTGCCCAAGAAGCGACGCGCTGCCGTCGCACTCtcgtcaacaacaacagcagcagcagttgctggtCCGCCCAGCAAGCGACgtcgcaacagcagcatcggCTCAACATCGCCGCACTCGACGACATTGCCATCGGGGCGGATCAAGTGCTTGGAGTGCGACAAGGAGTTCACCAAAAACTGTTATCTCACCCAGCACAACAAGAGCTTCCATTCCGGTGAGTATCCATATCGGTGCCAGAAGTGCGGCAAGCGTTTCCAGTGCGAGGATGTCTATACCACGCATCTGGGCCGCCATCGCACCCAAGATAAGCCGCACAAGTGCGAGCTCTGTCCAAAGCAATTCCATCACAAAACCGATTTGCGGCGACACGTGGAGGCCATCCACACGGGTCTCAAGCAACATATGTGCGATATCTGTGAGAAGGGCTTCTGTCGCAAGGATCATCTGCGCAAGCATCTCGAGACGCACAATCGTCCACGGGTCGTTGGCAAAAAGGCGgcggcagctgttgctgctgctgctgctgctactgctgctgcggcggcggctgctgcaacagccaaagcagcaacggcagcaacaaaagcagcaacagcggcaacagcagcaacagttgttgcTACTATTGCTAGGACGTCAGCTGacgatgttgctgctgacgATGATAGTTTGCTAGACGATGATGAAGACGATAATGATGcagagcagcaacatcagcagcagcagcagcaactgttgctgagCGGCGAGCATCatttgattaaaaacgaaTTTGTTGATATTAAGAATGAGTATGAGGAGGAATTCACGGAGGATTTTCATATTATTGAAAAGGATATTGAAATGTATTGA
Protein Sequence: MASIKSEMPPLHAAEALAASSSSSSSSGPTDSGGGGTAATAAAAAAATTAAAAATTTASAATVAGGSAPATPNANATISAAADSSDNQPGTPQPTTQQQSLMTVEAQQQQQQQQQQQASGITHQPYATHHMYAAAQQQPPQQQLYGGLYASDMQQQQQQQQQSYAASSYINSYEQFYQQQQQQQQQSAADYGGAYVDYSKASAVRYHPYLQQPTSVLPTAVAAATVAAVEDATGTAAAAVTTTAAASVAAMSPRVVSSSSPTSTSSHLQLSSATPSSPGGGCKLQCKKCGILNTNESELQEHIANVHGESPYGSSGYASSPYIKEEMPMPTPTAVAAAAAAAAAASGELLDLDSQKMVYHQQLLQQQQQQHHHHQQQQQQQHQQLHQHDAVVAGLPLALPDPLHSMQSMQQRALHSWEQQATPTEGLPAYMQPLLEKSPHYYGSPKQSPYHPSTVVKQEYALIKSEYADSQHYVDKSFDPTAAEVTTSPAEFPSTTTTDGNAVGGNAGTAYRGFEPPSSSSVLPANSLTAKAATWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISAHHHPARDPVTKTSRRGNAAAAAAAAAAAAAAAAAAATQEPPAVEPPRSPPDYGGGGGGVCGATGVQVGAAMSQYSASPSPTAQQQQQQLIASNGYANGHAHYHGHYNIQQQQQQQVQSTTNASPQHANSNNNSSSSNSSSSNNNNNSVLNGHPNGLAGPSAPINNNNNNNTQMPSSQMRGLLNNNNNNNNKITTINNNTTTTTIATTIKVEQMEDSSNSAMVMDQEQEEEQQQQQQQQQQLEEQQQQQHVLLQHHPLEQQEQVSYLLSRPYHSSNSNSSTTITTTSTNISSSNSNNNSSSSNSNSPPIIYHHHQQQQLPPQQQQLQPLQQQQQLEQEQQHQSHHHQLLQAMDFSRTQPLLPPPPMAALLPPITMDYNMLALDMQQQHSNMLQCSSISTPQQPLLPVTITTTPIHTPIPMHTHTPMPMPMAIHTPTTHTHTHINMDMECTTMQQQQPQQHYLAPQPLSPLPQPLQPQQLLLVDSNSSSSHSSSTASSHTPNSSSSSNHNSSNNISSTAATAVVGAQTAVAAATSSPPPPHIITSSSSNIISSSSNISNNSSSNISSSSNSSNNILPCYQQLPPVLEHTMSYHTIIGNEPGHYDTYTTSDGHQILQLMPAASLFAPYAPLSPYSVAAQRSPQEGDLPPVHTLTNALQAQQEAQQQQQQQQQQHQQHTTLTLLATPTPYSPTVSSSRATPALELDMVSLIAQQQQHEYEQYQLQQLEQQQQHIEQQQHIEQQQQQQQQLEQQQQQQLEQLQMQQTVAVLPKKRRAAVALSSTTTAAAVAGPPSKRRRNSSIGSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPYRCQKCGKRFQCEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETHNRPRVVGKKAAAAVAAAAAATAAAAAAAATAKAATAATKAATAATAATVVATIARTSADDVAADDDSLLDDDEDDNDAEQQHQQQQQQLLLSGEHHLIKNEFVDIKNEYEEEFTEDFHIIEKDIEMY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513060;
90% Identity: iTF_00502858;
80% Identity: -