Basic Information

Insect: Drosophila nigricruria
Gene Symbol: RREB1
Assembly: GCA_037075265.1
Location: JBAMCI010000035.1:15116284-15118308[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.5e-05 0.0011 19.4 0.6 1 23 444 466 444 466 0.99

2 6 0.0066 0.48 11.1 0.7 2 23 479 500 478 500 0.96

3 6 3.4e-06 0.00024 21.5 1.0 1 23 506 528 506 528 0.99

4 6 2.5e-06 0.00018 21.9 6.3 1 23 534 557 534 557 0.97

5 6 0.0013 0.09 13.4 5.2 1 23 564 586 564 586 0.94

6 6 8.5e-06 0.00061 20.2 0.3 1 23 591 614 591 614 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.5e-05	0.0011	19.4	0.6	1	23	444	466	444	466	0.99
2	6	0.0066	0.48	11.1	0.7	2	23	479	500	478	500	0.96
3	6	3.4e-06	0.00024	21.5	1.0	1	23	506	528	506	528	0.99
4	6	2.5e-06	0.00018	21.9	6.3	1	23	534	557	534	557	0.97
5	6	0.0013	0.09	13.4	5.2	1	23	564	586	564	586	0.94
6	6	8.5e-06	0.00061	20.2	0.3	1	23	591	614	591	614	0.95

Sequence Information

Coding Sequence: atgtcGGTTACGGAAGAATTCTATCCAGATGTAGAGAAATGGTGTCGCCTGTGCCTGAGGGAGCTCAAAGATGAGCACACAATCTTTGCCGAGGACGACACACAGCCATCCATACCGATGCGCCTGATGGCCTGTCTCTCCCTGGAGGCGAAGTCAACGGACGGATTGCCGAAGAAGATCTGCGGCGACTGTCGCTATCAGTTGGAGAAATCGTTTCTCTTTCGCCAGCGCAGCCAGGCGGCCGATAAGAAACTGCGCAAACACATCCGCCTGGTCAGCATGGGCAAAAAGAGCCGCGTCTTTGTCAAATCTTTGGACAACGAATCCGACGAGGACGAGCTCGAGTTCGAGGAGTCCATGGCATTCATAGCACAACTGGAAATGCTGCACGAAAGGGGCAGCCAAAAGTGGCGGGAAAAGTGCCAGCAGGATATGGAAAAGGAGTTCGAGAGTCGCCTCGACGCCGCGCGCGAGGAGTTCTGCAACGCGATGCGCAAGGAACTGGCGGATGAGGTGCGAGGTGATGTGCGCCAGCAGCTGCGCGACGAGGTGCAGGAGGAGAGCCGCAGGGAACAGCTCGCCAAGCTACTGGGTGAACTTGAGGTATTCTTGGCTGAAAAGAAAGCCGGTCTCTGGGAAACCTTAGGGGAGCTGCCAGTTGATCTAAAGCCAAAGAGCGAATCACCTGCACAATCCCCAACAGCACCAGCTCCAGCACCAGCCCCTATATCAACCGTTGAACAGCGTGTGACGCGTAAACGTGGTCGCATCTCCTCGTCGCCCGCAGCTAAGCAGAAGCGACGACCCAAGGCATCGCTTACCGAAAGCGCTGAGTATGTGCTCGAAACCGATTCCAAGGTGGAGGTGCTCTCTACGGGCGATGCGGAGATGGACGCATCTGCGCCAGATGCCAACGAGGGCTTTCGTGATATAAAGATGGTCGGCGCTGGCGATGTGGTAACCAGCCAAAATGGTGAGATCTACATTATAAATGCCGCCTCGTCGGCCAACTCGACGCCCAGCTCCTCTGCGGAGTTTCAGCAGGAGAAGAACATCACATCGTACAACATTAAGGACAATGGAGAGATTCAGTTTACGGACGCCAAGTCTGATGAAATCGGGGACGTAATGGTATTCAATCTGGACGATGATGGAGGCGACGACCAGCAGGTGTATGAGTTCAACGAAAATGTCATAATAGTGTCGAACGAGAAGGCAAACAGCGATGTCCTGACCTCGgccaaaagcacaaaaaatgATTTTGTGGTGAAACGAGCTCCGCGGAACTCGAAGCCCACTGTTGGACGCGTCAGCGACACGCTGAAGACGTTTCAGTGCCAGCTGTGCCCCATTTCGTTTGCCACGGAAAAGACGTTGTCGCGCCATCTGAGCACGCACATCAAGACGCTGAAGAATGGCACAGGCGGCGCGCTCAAGTGCCCCGtttgccagctgcagctgtccTGCGCCAGTTCACTGAAGCGTCACATGATCATCCATACAGGACTCAAGCCATACAAGTGCGATTCGTGCGATTTGTCCTTTTCGCAACGCGAGGTGCTCAAGCGccacatggacacacacacggGCGCGAAGCGACATCAATGTCCCCACTGCGACACTTGCTTCGCCCAGAAGACCAATCTGCAGCAGCACATCAACCGCATGCACCTGGACGGTGAACGGCAGCACAAGTGTCATCTGTGCAAGCGCAGTTTCAATCATGTCTCGGGCCTGAGTCGTCACCTCGTAGCCCACGCAGGCGTCACGTTTGCCTGCAAGGAGTGTGGGCGGCAGTTCAGCGATCGCAGCGCTGTGCAGCGACACGTCCAGAACGTGCACAAGGTGAAGGACACGGGCGGCGACTCCGCAACtgatggcaatggcaacgaaaCGGAGTTTGAATAA
Protein Sequence: MSVTEEFYPDVEKWCRLCLRELKDEHTIFAEDDTQPSIPMRLMACLSLEAKSTDGLPKKICGDCRYQLEKSFLFRQRSQAADKKLRKHIRLVSMGKKSRVFVKSLDNESDEDELEFEESMAFIAQLEMLHERGSQKWREKCQQDMEKEFESRLDAAREEFCNAMRKELADEVRGDVRQQLRDEVQEESRREQLAKLLGELEVFLAEKKAGLWETLGELPVDLKPKSESPAQSPTAPAPAPAPISTVEQRVTRKRGRISSSPAAKQKRRPKASLTESAEYVLETDSKVEVLSTGDAEMDASAPDANEGFRDIKMVGAGDVVTSQNGEIYIINAASSANSTPSSSAEFQQEKNITSYNIKDNGEIQFTDAKSDEIGDVMVFNLDDDGGDDQQVYEFNENVIIVSNEKANSDVLTSAKSTKNDFVVKRAPRNSKPTVGRVSDTLKTFQCQLCPISFATEKTLSRHLSTHIKTLKNGTGGALKCPVCQLQLSCASSLKRHMIIHTGLKPYKCDSCDLSFSQREVLKRHMDTHTGAKRHQCPHCDTCFAQKTNLQQHINRMHLDGERQHKCHLCKRSFNHVSGLSRHLVAHAGVTFACKECGRQFSDRSAVQRHVQNVHKVKDTGGDSATDGNGNETEFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532629;
90% Identity: -
80% Identity: -