Basic Information

Insect: Drosophila nigricruria
Gene Symbol: L
Assembly: GCA_037075265.1
Location: JBAMCI010000131.1:4735619-4744299[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00076 19.9 2.9 1 23 164 186 164 186 0.98

2 17 0.36 26 5.6 6.2 1 23 192 214 192 214 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 220 242 220 242 0.99

4 17 1.3e-05 0.00093 19.6 0.4 1 23 248 270 248 270 0.99

5 17 0.014 1 10.1 0.2 2 23 349 373 348 373 0.93

6 17 0.00032 0.023 15.3 0.2 2 23 404 426 403 426 0.96

7 17 0.064 4.6 8.0 0.7 1 23 489 511 489 511 0.97

8 17 0.076 5.4 7.8 0.3 2 23 519 540 518 540 0.91

9 17 0.021 1.5 9.5 1.2 3 23 551 573 548 573 0.86

10 17 3.5 2.5e+02 2.6 1.0 2 23 609 631 608 631 0.95

11 17 0.0026 0.19 12.4 1.1 1 23 674 697 674 697 0.97

12 17 0.0067 0.48 11.1 1.6 2 23 866 888 865 888 0.96

13 17 0.12 8.5 7.2 0.1 1 23 894 916 894 916 0.92

14 17 0.57 41 5.0 0.4 2 23 924 945 923 945 0.93

15 17 0.32 23 5.8 1.3 1 23 1046 1068 1046 1068 0.94

16 17 0.024 1.7 9.4 0.0 1 23 1078 1100 1078 1100 0.96

17 17 0.00023 0.016 15.7 1.2 1 23 1105 1127 1105 1127 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00076	19.9	2.9	1	23	164	186	164	186	0.98
2	17	0.36	26	5.6	6.2	1	23	192	214	192	214	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	220	242	220	242	0.99
4	17	1.3e-05	0.00093	19.6	0.4	1	23	248	270	248	270	0.99
5	17	0.014	1	10.1	0.2	2	23	349	373	348	373	0.93
6	17	0.00032	0.023	15.3	0.2	2	23	404	426	403	426	0.96
7	17	0.064	4.6	8.0	0.7	1	23	489	511	489	511	0.97
8	17	0.076	5.4	7.8	0.3	2	23	519	540	518	540	0.91
9	17	0.021	1.5	9.5	1.2	3	23	551	573	548	573	0.86
10	17	3.5	2.5e+02	2.6	1.0	2	23	609	631	608	631	0.95
11	17	0.0026	0.19	12.4	1.1	1	23	674	697	674	697	0.97
12	17	0.0067	0.48	11.1	1.6	2	23	866	888	865	888	0.96
13	17	0.12	8.5	7.2	0.1	1	23	894	916	894	916	0.92
14	17	0.57	41	5.0	0.4	2	23	924	945	923	945	0.93
15	17	0.32	23	5.8	1.3	1	23	1046	1068	1046	1068	0.94
16	17	0.024	1.7	9.4	0.0	1	23	1078	1100	1078	1100	0.96
17	17	0.00023	0.016	15.7	1.2	1	23	1105	1127	1105	1127	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACTTCATCGAGCTACTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAAttcacagctgcagcagccgcagcagcagcagcagcagcagcagcagcagcagcagcaggcacagcCTGGCGAGGAGGCCAAGGCGAATGGTGATGCTGGGCAGCAAAcggagctggagcaggagctgaGCAAGCCGAAGCGACCGGCACActtgcatcatcatcatcatcatcattaccATCATCAGCAGGCGCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAACTGGCTGCAGGACAAGGACAAGGACATGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCGAAGCTCTTCAAGCACAAACGCTCGCGAGATCGTCACAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACACACGACATCCAGAAGCCATTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTGACCTCCCACATGCAGAAGCATAAGAAGAATGCCGCAATCCTGGCAGCTGGCGGCAATCCCAATGCACTCAACTATAGTCCACGCTCTACGGGCTCCGCCTCGATCTCGAGCAATGGCAGCTTGCATAAGCGTCGCTATGCCTTGGCGCTGGCTTCTGACAGCAGTCCCAGTCGCTTGGAGTTTCCCAAGCGAGCGCGTGGCCAGCTAACGACCACGCCCACGGCTACAACAatagccacgcccacgccgcTGCTGCGCTGCAGCTACTGTCCCAAGGCAACGGAGTTCAGCAGTCTCGAGCAGCTGAATGCTCATCTCCAAAGCACAcacgaacagcagcagcagcagcaacagcaacagcaacagcagcagcaacagcagcaaaaggaTTCGGACGGTCAGACAAATGGATTCCAATTGAGCTGCGAATATTGCACAATGAAATTTGTGAATATTGCGGCGCTGTTCCAGCACATGAGAGTGACGCACTTGGATCGTCTGAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGCCTCGGCTCGCCGCAGTCGAAGCTCAAATCGGATCTGGCGACGTCGGAGAAACCCGAACAGGAGCTGCCCACAGACCTGAGCAGCAACAAGCGACGTCCGCTGACATCGCCCACTCAGCCAGCGCCTCCGCCGGGCATCTTCTTCTGCAATCAGTGCAACGCAGGCCTGCCGGACTTCGAGAGCTTTCGCAATCATCTCAAGAGTCACATAGCCGAGGGCATGCAGCTCATCTGTCCGCATTGCGGCCTGAGTCTGCCCGAGCAGTGTGAGTACGAACGTCATGTGGTCGCTCACTTCTTGATCAGCAGTTCGGAGTTCAATTGCTGCAGCGCCAGCTGTGGCAAGTCGTATGCCAAGGCTGAGGAACTGCATCAGCATCTGCTGGCCGAGCACGTCCAGACCATGCTGAAGTGCGTGCTGTGCTCGGAGTTGTGTGAGAATCGCATGTCGATGCAGCTGCACTTGGCCTGTGCGCACAGCCAGGAGTCGAAGCTGCTGAGATGCAGCGCCTGCCTGGAGCTCTTCCGCAACGATGCCGACTTCCATGTGCACGTCAAGACACGCCATCAGCTGGGCAATCAGGGCGTGGGCAATCCACCAGCTCCAGCCAATCCGCTACAGTGCATGTTCTGTCGCGCCGTCTGCTCGTCGGAGCTGGAAATGCATTTCCATTTGGCGGCGCATGCGCGACAATTCCGCTGTCCCAGCTGCCCGGAAACGTTCCATGTGGAGTTCCTGCTGGACAGGCATATGCAGAGCCAGCATGGCGGCATCAAGGACAAGGAGTCGCCTGTCGCTGGCATGGGCAGCTTGTATGTGAACGCATTGCTGCCGCctctggctgcggctgctgcagccgctgccgcagcaaacaatgccaacaacaacaacaacaacagcaacctgCATATAGACTACAATGTCGCCTTCAAGGGTCTTTTTGGTGGCAACAATCCGCCGAGCAAGTTCTACAACAGCCCATTGCAGGTGGACACCAAACAAAGTCCACATCCGGCCCTGATGTACGGCCTGAGCCAGCGCTACTTGATGGAGATGTACGCAGCGAAGGCCAATTCCCCGGCCAATGCCGCCAGCGCCGCTGAGCTGCCCACGCCTCAGGCCGTGCAATCCTCGACAGCGGcgagcgccagcagcagcagcaacaacagctacagctgtGGCATGTGCGAGCGTCAGGACTTGCGCAGCGAAGCCGAGCTGCACTCCCATCGGAAACTCGCTCACAATCTGAAGACGGGCGTCAGTCTGAGGTGTGCCTATTGCTCGGGCAACTATAAGAGCCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGTCACAATTCAAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTTCCCTCGCCAGCCATACTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGTGCCCACTGTggccagcagctggagcatGTGGCCGCCTTTCGGGCTCACCTCGGCGAGCATGGTAACGATGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAAACACTGCACTCGGAGTTCGAGCTGAGTTTACACGCCAAATTCCATACCAAATCGTCCAGCTGCAATAGCCTGCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGCTACCCGGCGCTGGTGAAACCGCCAAGTTGTGTGACAAATGTTGCCGCAAACACAATCTGAATGGCAAGCGCAAGGAGCAAGTGCAGCCAACAGCTGTAGCTGtcccagctgcagctgccgctgccgtggCAGCTAGCGCCTATCTGGAGCATCGTTGCAATCTGTGCAAAATGATCTTGCCACATGCCCAGAAGCTACAAGAACATCTTGTCGAACACACTTTTGCGGGCACTGAGCAGCGTGGCTACAATTGCTACATCTGCTCGGCTGTGTTCACGGCGCCCGGTGGCCTGCTCACCCACATAGCGGAGCACGGCACGCGTCCGTATGACTGCAATTTGTGCCCGGAGAAATTCTACTTTCGTGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCGCCCACAGCCGGCAGCAGCACGTCCCAAGCAGGAGACGCATAGCTCGACGGCCAGCTCACCCCTGACGCTCAGTCCCAGCCATGTCAAGCAGGAGCTATACGAATCGGAGCCAGCAAATTCTCCCAACGCTGCTGAGCTGCCCGCACAGCCGGACGAGGAGGAATACATCGAAGTGGAGCAAGTGCCGCAGGAGACGCTGCGAACTGGCGAGCTGCTAAGCACCGAGCgttccagcagcagcgcctAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQQQQQQQQQQAQPGEEAKANGDAGQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTTTPTATTIATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQQQQQQQQQQQQQQKDSDGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKLKSDLATSEKPEQELPTDLSSNKRRPLTSPTQPAPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQGVGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVAGMGSLYVNALLPPLAAAAAAAAAANNANNNNNNSNLHIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANAASAAELPTPQAVQSSTAASASSSSNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSSSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPTAVAVPAAAAAAVAASAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLTHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRPQPAAARPKQETHSSTASSPLTLSPSHVKQELYESEPANSPNAAELPAQPDEEEYIEVEQVPQETLRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00502755;
80% Identity: -