Basic Information

Insect: Drosophila nigricruria
Gene Symbol: -
Assembly: GCA_037075265.1
Location: JBAMCI010000179.1:2601534-2605347[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.3 2.4e+02 2.6 8.1 2 23 343 365 342 365 0.95

2 17 0.0075 0.54 10.9 1.6 2 23 408 429 407 429 0.94

3 17 2.3 1.6e+02 3.1 1.6 2 17 440 455 439 466 0.80

4 17 0.03 2.2 9.1 1.4 1 23 497 519 497 519 0.95

5 17 0.0073 0.52 11.0 0.1 1 23 527 550 527 550 0.96

6 17 0.00044 0.031 14.8 0.3 2 23 555 576 554 576 0.97

7 17 0.15 11 6.8 0.0 1 20 584 603 584 605 0.94

8 17 0.0001 0.0074 16.8 0.4 1 22 624 645 624 648 0.90

9 17 0.03 2.2 9.0 0.5 1 21 653 673 653 674 0.93

10 17 0.0044 0.32 11.7 0.4 1 23 693 718 693 718 0.96

11 17 0.13 9.1 7.1 3.7 2 23 734 756 733 756 0.93

12 17 0.00096 0.069 13.8 0.3 3 23 763 784 761 784 0.92

13 17 0.024 1.7 9.3 0.4 2 23 788 810 787 810 0.96

14 17 7.5e-06 0.00054 20.4 1.2 1 23 816 838 816 838 0.98

15 17 0.03 2.1 9.1 0.6 1 23 842 865 842 865 0.93

16 17 4.8e-06 0.00034 21.0 0.9 1 23 871 894 871 894 0.97

17 17 0.00064 0.046 14.3 0.5 1 23 898 926 898 926 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.3	2.4e+02	2.6	8.1	2	23	343	365	342	365	0.95
2	17	0.0075	0.54	10.9	1.6	2	23	408	429	407	429	0.94
3	17	2.3	1.6e+02	3.1	1.6	2	17	440	455	439	466	0.80
4	17	0.03	2.2	9.1	1.4	1	23	497	519	497	519	0.95
5	17	0.0073	0.52	11.0	0.1	1	23	527	550	527	550	0.96
6	17	0.00044	0.031	14.8	0.3	2	23	555	576	554	576	0.97
7	17	0.15	11	6.8	0.0	1	20	584	603	584	605	0.94
8	17	0.0001	0.0074	16.8	0.4	1	22	624	645	624	648	0.90
9	17	0.03	2.2	9.0	0.5	1	21	653	673	653	674	0.93
10	17	0.0044	0.32	11.7	0.4	1	23	693	718	693	718	0.96
11	17	0.13	9.1	7.1	3.7	2	23	734	756	733	756	0.93
12	17	0.00096	0.069	13.8	0.3	3	23	763	784	761	784	0.92
13	17	0.024	1.7	9.3	0.4	2	23	788	810	787	810	0.96
14	17	7.5e-06	0.00054	20.4	1.2	1	23	816	838	816	838	0.98
15	17	0.03	2.1	9.1	0.6	1	23	842	865	842	865	0.93
16	17	4.8e-06	0.00034	21.0	0.9	1	23	871	894	871	894	0.97
17	17	0.00064	0.046	14.3	0.5	1	23	898	926	898	926	0.89

Sequence Information

Coding Sequence: ATGTCGGAAAACtcgaaaataaacaacaacgaaaatgGGCTTAGCTGCCTGCATTGCAGCGTGTACAATTCAAAACAGCAATATCATGAAATATTCGATGAAGTGGGCAtcgaaattgaatttgctCAATTGTTGGCTAAATATTTCCAAATCGTTGTCAAACCCGACGCGGAAAAGTCGCAACTGTTGTGTCAAGAATGCATAAATACGCTAATACGCTTCTTTGACATAGATGAGCTGCAGCGTGAACAGGATGCGGCCAACGCAGCCAAGaaggcagccaagcagccgGAGGAGTCGCCAGGTGCTGGCGCTAAAAAGGCTGAAAATCCCGCTAAAAAGGCGACGCCAAAGGCAAAGAGCGTCACAGCTGCCGTCAAAAGTTTGCCAACGCCTGTTAAATTGGTTAAGCCAGCAGCAGTTACTGCCTCTGCTGCCGCACCCAAAGCCGCTCCAGATAGCCTAGGCATACGCATTACCCGAGCCCGTTCGGGTCCGCCCAAACGTTTGCCTGTCAAGGCCAAGGAGTTAGTTAAGCCAAATGCTAAAGTCAAGGCGAAAAGTCATGGCTCCGCAGATCAGGAACAGATCAGCGCACTCATACGCGATATACTGGATGATGAGGAGGCGCCAGCAGATGAGAAATTTGCCGAGGCCGCAGCCACAGTAAGGCAGCTCGAAAAGCAAACAGGCAAAAAGCAGCAGGATGCAACGGAGCAGCTGGACGAAGAGGATAACAATGATGAGCTGGAGTTTCTGCTAGAGCAAGATGACACCTCCTCCGACTTGGATGTGCGTAATTTCAAAGTGGAACGCAAAGTTAAGCGCGCTGCCTCGCAATCCCAATCCCGATcgcagtcccagtcccagtcgcAGAATGAAACCCAAAGCGAGGATGAATCCTTTAAAGTGGAGCCCTTTAATTTTGTCTTGATCAAAGAATCTGACAACATTGGCGATCTGCATGAATATCTGTCGACTGTGGTCAAGACGTGCTTTGAGACCTTGCAATTTGACTGGGCCACTGTGTGTCGTCATTGCTCGCTTAAATGTAGCAAATATGAGACTTTGCTCAATCACATGCACAAACGTCATAAGCTGGCGGATGAGCGCTACAATTGTCCCATTGAAGGCTGCACGGCGGAGCTGCAGGGACGCAAATATCTAGCCATGCATTTGGTGGTGCTGCATGCGCCTGTGGCAGAaATACCCATTTATGGCAAGTGTCCCGAGTGCAATATGACCTTCTCCAATATATTGCAATACAACAAACACTCCTGCGCGCATGTCATTAAGAAGCGTCGCGGCATACGTTTATACTGCGAGATGTGCGGCTTGGAGTTTCCCTCGTGGAAGCGCTTTAATTTCCACAATCAATTTCATTTGGAAAACCACAGGCCGCGCGCTTGCTTCGTTTGTAATTTTGCGGACAATAACATCGATGAGCTCTTTCATCATTTGCACTATGCACACGAGCCAGAGGGCACACACTTCTGTGATCTTTGTGATCGCAACTTTCGCGATGCTGCCGTGTTTATGGAGCACAACAAATCCCATTCGAATGTCAGCAGCACCACCTACAGCTGCTCGGAATGCAGCGCCAACTTTGAGACTCGCGGTCGTCTCAATGGACATCTGCGCGCTGTACATGGCAGTGTCATTAGCTGCGAGCTGTGCAGTCGCGAGTTTGCCACAGAGGCCACCTATAACCTGCACATGAAGACGCATTTGATCATTGAGCGTGAGGTGCATGTGTGCAGCGGTTGCGGGCTACTCAGCGAGAGCAATGAGAAGCTGCAGGCTCACATTGAGGCCGAGGATTCGTCTTGCTTTGGCATGGATACCTATGTGGAGCTCTTACGCAATGCTTATGTCTGTGAATATTGCTCGGCGTATTTTAAGCAGAAGAGCGATTTGCGTGCTCATCGTGATTCGGGCGTGCATAAGGATGGCTGCTTCATATGCCAGCCCTGTGGCAAGGAATTTGCCGACATGAAACTCTATCGTCATCATCTGCGCAACTTTCAGCAACAGCGCTCAGATTTGGCGCATCGTAAGCTAGAGATATGTCTCTACTTTATGTGTGACTATGAGGATTGCACTGAGGCATATGTTAACTGGAACTCGCTGTACACACACAAGCGACGTTTGCACGAGACCATTGCGAAACAGGAGCCGCTAGTTAAAGAAAACGAATGGATCTGTCAGTTCTGTCAGAAACACTGTCGTTCCAAAATGTCGTTATCCGTGCATGTGGCGCGCAGTCATAATAATAATAATGTCATTTGTCCGCTGTGCAAGGCCTCGTATAAGGATAATGATGCCTTGACTAAACATCATGCCTATTGGCATGAGCCTATGGAATGTCGTTTGTGCTTGAAAGTGGTTAAGAATCGTCGGAATTATGATACCCATATGAATGTGGTGCATTCAAATAACAAACGGTATTCGTGCAGTGTCTGCCCAAAGGGTTTCTATCATAAAAGTGAAATGGAGGCGCATCAGCGGCTGCATAGCCAATCGTATAGCTGCGAGCAGTGCAGCTTCATCACGCGGAACAAGAAGTCGCTGTCGGTGCATGTGTTGGGCCAGCACTACAAGCGCTTCGCCTTCGAGTGCAAGGAGTGCGACAAGCGTTTCGGACGTCGCCAGGGCCTGTCGAATCATATGCAGCGTGTGCATGGCTCCAGGTATACTTGCCGCGACTTGTATGACGGTGGCTGCAGCAAGTCCTTCAGCTCGACGACGCAGCTCAATATGCATGTGCGCAAGGCGCACAATGGCAGCATTTATCTGGAGGATGATACGATCAAGGGCGAGGAACtggatgaggaggaggaggaagaggaagaggaggagaaggaagaggaggagcaggagcaagagcaggagcaggaggaacAAGTGACCAAGGATGGTCCGTCGACATCGAAGAAACGCTGCATACGCATCAATGCGAATACACAAATCGAGTTTATTGGCGACTCAAAAGCTATGGCCGAGGATCATGAGGCAGATGACGGCGCCGAGATGCTAGAGGAGCCGACGAGACCGAACAAGAAGCAAAAGCTAACTTAA
Protein Sequence: MSENSKINNNENGLSCLHCSVYNSKQQYHEIFDEVGIEIEFAQLLAKYFQIVVKPDAEKSQLLCQECINTLIRFFDIDELQREQDAANAAKKAAKQPEESPGAGAKKAENPAKKATPKAKSVTAAVKSLPTPVKLVKPAAVTASAAAPKAAPDSLGIRITRARSGPPKRLPVKAKELVKPNAKVKAKSHGSADQEQISALIRDILDDEEAPADEKFAEAAATVRQLEKQTGKKQQDATEQLDEEDNNDELEFLLEQDDTSSDLDVRNFKVERKVKRAASQSQSRSQSQSQSQNETQSEDESFKVEPFNFVLIKESDNIGDLHEYLSTVVKTCFETLQFDWATVCRHCSLKCSKYETLLNHMHKRHKLADERYNCPIEGCTAELQGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLENHRPRACFVCNFADNNIDELFHHLHYAHEPEGTHFCDLCDRNFRDAAVFMEHNKSHSNVSSTTYSCSECSANFETRGRLNGHLRAVHGSVISCELCSREFATEATYNLHMKTHLIIEREVHVCSGCGLLSESNEKLQAHIEAEDSSCFGMDTYVELLRNAYVCEYCSAYFKQKSDLRAHRDSGVHKDGCFICQPCGKEFADMKLYRHHLRNFQQQRSDLAHRKLEICLYFMCDYEDCTEAYVNWNSLYTHKRRLHETIAKQEPLVKENEWICQFCQKHCRSKMSLSVHVARSHNNNNVICPLCKASYKDNDALTKHHAYWHEPMECRLCLKVVKNRRNYDTHMNVVHSNNKRYSCSVCPKGFYHKSEMEAHQRLHSQSYSCEQCSFITRNKKSLSVHVLGQHYKRFAFECKECDKRFGRRQGLSNHMQRVHGSRYTCRDLYDGGCSKSFSSTTQLNMHVRKAHNGSIYLEDDTIKGEELDEEEEEEEEEEKEEEEQEQEQEQEEQVTKDGPSTSKKRCIRINANTQIEFIGDSKAMAEDHEADDGAEMLEEPTRPNKKQKLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512900;
90% Identity: -
80% Identity: -