Dnig006474.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila nigricruria
Gene Symbol
hang
Assembly
GCA_037075265.1
Location
JBAMCI010000107.1:11290922-11305710[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.39 28 5.6 1.0 3 23 503 524 502 524 0.93
2 18 1.1 80 4.1 3.2 3 22 631 650 629 650 0.89
3 18 0.00083 0.059 14.0 3.3 1 22 757 778 757 780 0.90
4 18 0.095 6.8 7.5 0.1 2 21 792 811 791 812 0.93
5 18 0.00096 0.069 13.8 0.2 2 23 934 956 933 956 0.95
6 18 0.0028 0.2 12.3 0.1 1 23 964 987 964 987 0.96
7 18 0.00021 0.015 15.8 0.2 2 23 1073 1094 1072 1094 0.97
8 18 0.0004 0.028 15.0 2.9 2 23 1199 1221 1198 1221 0.97
9 18 0.031 2.2 9.0 0.2 2 23 1230 1252 1229 1252 0.95
10 18 0.0017 0.12 13.0 0.1 1 23 1265 1288 1265 1288 0.97
11 18 0.00017 0.012 16.1 1.1 1 23 1330 1352 1330 1352 0.99
12 18 0.0027 0.19 12.4 0.9 1 23 1360 1383 1360 1383 0.96
13 18 0.094 6.7 7.5 0.4 2 19 1391 1408 1391 1409 0.94
14 18 3.6e-05 0.0026 18.2 0.4 3 23 1519 1539 1518 1539 0.98
15 18 0.007 0.5 11.1 0.1 1 23 1574 1596 1574 1596 0.97
16 18 0.00082 0.059 14.0 0.6 2 23 1684 1706 1683 1706 0.93
17 18 0.0089 0.64 10.7 0.3 3 23 1762 1782 1762 1782 0.98
18 18 5.2e-05 0.0038 17.7 2.3 1 23 2243 2265 2243 2265 0.99

Sequence Information

Coding Sequence
ATGTGCGACGCTGtcgcaacatcaacaacaacaacaatgccagccgcagcagcaggatCCGGATCAGCAGTGGCTGCTGGCGATAGCACCTTGATAGCGATGGAGGAGCGTCAGCGCCAAAGTTGCTGTCGTCTATGCATTGCGCCCGCCAGCGAATGCATTTCAATCATTAACAGTTATGCGGCCGATAAGGAACCGTTGGCCACTAAAATACACAACTGCGTAAATATCAAGaTCACGCCATTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTTAAAAATCGCTGCCTCAGCTCACAGTCCAAGCAGCGCCTATGGCTGGACAGcgataaaagcaaacagcagaCGCTTCTCGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCAGCACCATCGAacttcagcagcaacaacagcagcatcagcacgAGTCGAATATCGATTCGGCAACGATTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATTCCTTCGTTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacatcaacagctacaacaacagcagcagcagcaacaacagcaacaacaacagcagcagcagcaggtgcagcatgctgcagccagagcaacgaGCGCGGCGGCGGAATCACAGCAAACGCTGCAAACCCTTTTATTGCAGGTGccctcaacagcagcagcagcagcagcagcattggcAACGACGtcaacgcagcagcagcaacagcaacagcgcaaatatcaacagcagcagcaacgtgtcaagcaacaacaacattatcaacaacaacatcaacagcgtTTGAGTCGCATTCGTCAGCCGCGACGCCAGCAACAGGCGACCATGTCCGCCCAGCGCCTGCTTAAATTTAAGCCGAAATTGTATTTGCCACTGGATATAACGGTGCCAGCGCTGCCGCCACTGTTGCCGTCGGacactgttgctgctggtgctaaGTTGGCGCCGTTGCCtgtgccgttgccgttgccgcttgATTTTAGCCAGAGTCAGTGTCAGCAGAAACAAGGCAACGTATTGCCATTGCCGCCGTCGACGCcgctgccagctgcagcaacaatgaGCAGCAacgccgctgcctctgcctctgcctctagcgctgcctctgcctctgcctctgccgcagTCACGACTCCACTGCTCATGCCGCCGCTGCCCGCCGTGCCGATTAAGGACGAGCCCATTGATGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAACATGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCGCTGCCCGCCACCGCGGTCGCAAACGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGTCGTGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAACGCCCGTCGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCGAACAATACGCCCATCACAAAACCAACGCCGGCACTGGCCGCCGCCCTGGAAATTCAGCGTGccgcagcggcggcagcagccacCGCGGAGGCAACCAAAGCCGCCGCCGGCGGCAATATATCAGCGCAAAAGTACCGTCAAGTGGTCATGAATACGTTCATCAAGTGCGAGAATGGCGGCTTCGACTACGACAATCCGGAACAGTACCAGCAGCTGCTCACGCGCGACAAGGTGGACTTCATACAGGAGAACAATGAGTTCCTCGAGCAATACCAGACGATGACGTGTCGCTGCTGCAACAAATACTTCAACACCTACAAGAACTTTATGGCGCATGTCCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCACATCTAAAGAAGCGCAACTGCATCAATTTGTATCGTGTTCTGAACGCTTTGCGCGTAAAGCTGCCAACCTTTTCGCATGCCAATGCATCCGGCGTGGCTGTCTCCGCCGATTTGAGTATTggccaggcagcagcagcagcggcaatagtcgcagcagcagcagcagcaaatgaacTGAAGCATGAAACATCCACGGAGCGGCCAGAGAAGCTGCGTGCCAAGGAGCTGTTGGTGAACAAACTGTACGAGTGCAAGCTGTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTCCGTACCCATGTCTATGACAAGCATGCGGATGTGCAGCGCAAGGACAACAACTCGATACAGTGCAGCTTCTGTGGACTGGACTTTGCCGATCCGGTCGATCGGCGTCGCCACTACAACAATATGGAGTGCATTGTGCGCCTGCGCTGCATGACCTGCGATGCCAAACTGGAGACGCATCAGCGCTTTCTCGACCACGTCTACCAGGATCATTTGGGCGGCGTGAGCAGTGATAATGCATCGACGGCCAACAGCGGCATGGATCATTCGCCGGGCAAGCGCAGCCTGCTGGGCGCCTTGGGCATCGGTGTGAGTCAGTCGTCGAACGATGAGTCGCGCAGCAgcacgcacaacaacaacaatgctgtGGATTTGCCCTTTACCTCAACGCCGAAACcaggtggaggaggaggagcagcagcgaCGGCCAGTGGCAGCTCCAGTCGCGATGCACCCAAATCGCAGTATTTTTCCCGCATGCCGCAGGTGTGCCCCATTTGCGGCCAACagtacaacaactacaacaacgtGCTGCGTCACATGGAATCGAAGCATCCCAACAAGCTGCCCGAGACCTACAAGTGTGTACGCTGCGGCCTGGGCTATCCGCGAATCTCCTATCTGCGCGAGCACATGATCAATGTGCACGGCGTGGACAAGAACCGGCATTCCGGCGGCTTTGAATACATTGTGAATGCCGATGCCGTCAAATTGGCGGATGGCAGCACGCCGAACGTTTATACCGGGCGATATGATTATGTGATGAAGGATCTGATGTCGATAACAAATGGTGGGACACTCgATGACGATGAGGAGGAAGGCGGAAGCGTTGCCAAAAAGATGCGACTcgacgacagcagcaacaatagcagcatCAACATGAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAACATTGGCTTGTCGAATCATATGCGCTCGCATTATACAGCTTCGACGGCCACGAATGCTGCGTTGGCGGCTGCCAATCGCATGACACCCAAATCTTTGACAATTACGGCAACGCCACCATTAGACACGACTGCAGCAACGTCCACGAGCATAGCGCCCGCACCAACTAcaacttcagctgcagctgcagcagcagcatcaacatcaacagcaacagcaactgcaactgcaactgccgtcggCGCTGGCGGCTTACCGCCCGCAATGGTGCATCAGACGCCACAGGAGCAGGCCGTATTCCGTCGCAGCTTGGATCAGGCAGCCGATCGTCGCTTTCGCCGCATGCGCTGTCGCATCTGTCAGCGGCGATTTAGCTCGAAGAAATCATATCGCTATCACATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGTAAGCTCTGCAATGCCGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCACCTGTTCAAGGTGCACGGACGAGCCATCAAGGACGAAATGATAATCAAGCAATTCGAGTGCGATATCTGCTCAATTGTCTACAGCtcggagctggagctgcagcagcacaagCGCAGCGTGCACAAATCCCAATTGGGCGCCAACGATGCCACATCCAAATCAGCAACCAAATCATCTACCGCTACCTCAGCTGCTGACCTGGCCGACACAGGGAGCACAGCCGTGGCCGTGCTACCACTCTACTGGTACCAGTGCAAGTACTGCCCATCGAACTTCAATACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTATTCGTGCAAGGATTGCGGCAATGTCTACAGCGGACGTAAGAGCCTCTGGGTGCATCGCTATAAGAAACATCCGCAGGTACCGGATCCGGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTTGATCGACAGATGCTGGAGAATCATACGCCCACCTGCAATCGGAAGCCAATTACTGCCACCGGCGCACATCAGCAagatcagcatcagcagcaacaacaacaacaacagcagcaacaacacctgcagcagcagcaacaacagctgcaacaacatcGCGCCATATTCAAGCATAAAACGGGCGATGATGACGACGAGGAGGAGGACGATAAGCTAATGCTGCTGGACGATGGTGCCGTTGGCAGTGATAGCAACGGTGGCACTGCGGTGGTGCATGCACCGCCCACCACCAGCATCAGTACCAATCCAAATACGATAAATGCGAGCACACTGAAGATACGCATACCGGAGGTGGCGTGCACCATCTGTGGTGCCCGCTTCACTGATCAGGAGATGTTCACCAAGCATATACAGAAGCATGAACAGGATCTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCCGATGCTGGCCAATTTCAGGTGGAGCGGCAGAACGAGAACGGGGAATATGCGTGCGATTTGTGCGCGAAAACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCGACGGCGAAGCGACAACgctgaacagcaacaacaacaacaacaacaattcgcTGAGCTCCTCATCGATGCTGCGCGAGCTACATGCCGTGGGCCTGATGcccaaccagcagcagcaccagaagcaactgcaacaacaacagcagcagcaacaacaacagcaacagcaacaacaacggaaCAACACATCGAGCAGCTCCAGCAAGTCGATGAAGCGCAAACGTGAGCTGAAATGCGAATATTGTGCCTCCACATTCATAAGCAATAATAACCTGCGTCGCCACATGTACGAGCTACATAAGCACGAGGTCAGCAATCTGCCAGAGCCGCCAGTTATTGAGGTGGACAAGCCGCTGACGTGTCGTCGTTGCGGCGATATACGCTTCGATACCAAAGAGCTGTGGATCGAGCATAAGCTGGCGGACGCCAAAGTCGTACGTCCCTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTCATCAATCATATTAACAATCATCTCAAGGAGGATGTGATAGTGCCTGTGGCAACGGTGGCGACAGCTTCCAAGGCGCCATCGGTTGCCGTGCTGCCCAACAAGAATGCAACAGCTAAAACAACagctgaaacaacaacaacaacaacaacggcagcaacaggagcaacagcagcaacaacaacgggaGTTGCAGCAAAGGGCATAATTAgagcggcgacggcggcggcgacaACACCAGCTGGCGGCAGAGTTAATAAGAGTAAACAACTGGAGGAGCAGCTGACAATGAAGGtggcaacaaaacaacaacaacaacagcagcagcaacaacaatcgtcAAATGTTGCTAATGCTGAGCAGGATGATGAGGAGGACAATAGTGATATggacgatgatgacgatgatgatgatgatagcGATACTGGCGATGGGGATAGCACAagtgctgatgatgatgacgatgacgacgacgatgatgatgacgatgagggcgatgttgacgacgatgatgaagATTTGCATGGCGACGTTGTCGGACAATTGctgcaacagaaacaacagcagcagcagcagcagcccctcaacagcaacagcaacgatgatgacgatgatctCATTGAGGAGGTCATCGAGGACGATGGTATTGTCGAGGAGTtggacgatgatgatgaggaagatgatgatgatgatgatggaaATACCACTGATGAGCACCAGCAGCTGGCAGCCAATAATACCAAGCAGCAGGGGCGACGCCTCAACTTTGACTACACGCGCTCCAACAACGCCAAGCTGAACGGCAATGGCAAACAGACGTTGGCCAAGTCGAAGCGTCAGCTGGTTATGCACAGCTCTGAggatgatgaggatgaggatgtCAACGATGGTGCcgaggaagaggaggaggatgaggatgatgaGGGCGTGGGTGAAGCAATGACCATTGATGATATTATTGAAGAAGATGATGGGgaggatgaggatgatgaTATGGTTGGTGTTGATGGTGGTGTTGTTGaagacgacgatgatgatgatgatgatgatgttgaagAAGACATggatgaagatgatgatgacgatgatgatgacgacgacgacgacgatgacggcGTCAATATTGGCAGCAACAATCGTCGTCGCGACGGTGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGTGAGGCTGATGCGGATGGTGATGGTGATGGTGATGCGGATGGCGATGGTGATGGTGATGGCGACGGCGATGCTGATGGTGATGTGGATGCTGATGCTACATCATCATCGGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCAGCTGCAGTCACATATTAAAAGTCATTTTCTCAATGGTCCATCGGcgggtggcagcagcagcagtagcagcagaagcagcagcagcagcagcggcggcgccGGTAATAGCAGAAGAATTGGTGTGAgtgcgagcagcagcaacagcagcagcaggaccaacagcaacaacaacaacaacaacaataataacaataataataataataatagtaataataataacagcaaAAGTAAAACCAAAAAGTCCGGCTTGGATGCAACGAAAGCTGacagtgctgctgctgctgctgctgcaacagcaacaacaacagcaacaacaagagcaacaacaacagccgcagcaacgacaacggcaacagttgccgccgaaacagcggcagcaacagcagctgccgaGGCAGCCAACAGCTTGAACTGA
Protein Sequence
MCDAVATSTTTTMPAAAAGSGSAVAAGDSTLIAMEERQRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRLWLDSDKSKQQTLLGYLDLNKTENGSSTIELQQQQQQHQHESNIDSATIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQHQQLQQQQQQQQQQQQQQQQQVQHAAARATSAAAESQQTLQTLLLQVPSTAAAAAAALATTSTQQQQQQQRKYQQQQQRVKQQQHYQQQHQQRLSRIRQPRRQQQATMSAQRLLKFKPKLYLPLDITVPALPPLLPSDTVAAGAKLAPLPVPLPLPLDFSQSQCQQKQGNVLPLPPSTPLPAAATMSSNAAASASASSAASASASAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPATAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVDFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRVKLPTFSHANASGVAVSADLSIGQAAAAAAIVAAAAAANELKHETSTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSTHNNNNAVDLPFTSTPKPGGGGGAAATASGSSSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEGGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITATPPLDTTAATSTSIAPAPTTTSAAAAAAASTSTATATATATAVGAGGLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKSQLGANDATSKSATKSSTATSAADLADTGSTAVAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQHQQQQQQQQQQQHLQQQQQQLQQHRAIFKHKTGDDDDEEEDDKLMLLDDGAVGSDSNGGTAVVHAPPTTSISTNPNTINASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTLNSNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQQQQQQQQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDKPLTCRRCGDIRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATVATASKAPSVAVLPNKNATAKTTAETTTTTTTAATGATAATTTGVAAKGIIRAATAAATTPAGGRVNKSKQLEEQLTMKVATKQQQQQQQQQQSSNVANAEQDDEEDNSDMDDDDDDDDDSDTGDGDSTSADDDDDDDDDDDDDEGDVDDDDEDLHGDVVGQLLQQKQQQQQQQPLNSNSNDDDDDLIEEVIEDDGIVEELDDDDEEDDDDDDGNTTDEHQQLAANNTKQQGRRLNFDYTRSNNAKLNGNGKQTLAKSKRQLVMHSSEDDEDEDVNDGAEEEEEDEDDEGVGEAMTIDDIIEEDDGEDEDDDMVGVDGGVVEDDDDDDDDDVEEDMDEDDDDDDDDDDDDDDGVNIGSNNRRRDGAVMVSGISIGDGEADADGDGDGDADGDGDGDGDGDADGDVDADATSSSESESTTTTSHSIGERRKKSVVKSAAHGAAADQSNSSYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGSSSSSSRSSSSSSGGAGNSRRIGVSASSSNSSSRTNSNNNNNNNNNNNNNNNSNNNNSKSKTKKSGLDATKADSAAAAAAATATTTATTRATTTAAATTTATVAAETAAATAAAEAANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00573462;
90% Identity
-
80% Identity
-