Dnig002685.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila nigricruria
Gene Symbol
-
Assembly
GCA_037075265.1
Location
JBAMCI010000035.1:16349542-16354185[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0013 0.094 13.3 1.4 1 23 218 240 218 240 0.97
2 26 0.047 3.4 8.4 2.0 1 23 246 268 246 268 0.97
3 26 0.31 22 5.9 0.8 2 20 300 318 300 321 0.94
4 26 0.0029 0.21 12.2 1.5 1 23 398 421 398 421 0.93
5 26 6 4.3e+02 1.8 4.2 2 23 432 455 431 455 0.93
6 26 3.9 2.8e+02 2.4 0.3 1 19 461 479 461 481 0.89
7 26 0.21 15 6.4 1.4 2 23 496 517 495 517 0.97
8 26 0.025 1.8 9.3 1.2 1 23 597 620 597 620 0.95
9 26 0.00014 0.01 16.4 0.1 1 22 629 650 629 650 0.96
10 26 0.064 4.6 8.0 1.0 1 23 659 682 659 682 0.96
11 26 0.0011 0.08 13.6 0.2 2 23 714 735 713 735 0.97
12 26 1.5e-05 0.001 19.5 5.7 1 23 743 765 743 765 0.99
13 26 0.03 2.2 9.0 1.0 1 23 913 936 913 936 0.92
14 26 0.0037 0.26 11.9 0.4 2 22 944 964 944 964 0.96
15 26 0.25 18 6.2 0.7 1 23 973 996 973 996 0.90
16 26 1.2e-05 0.00088 19.7 1.8 1 23 1021 1043 1021 1043 0.97
17 26 0.00014 0.01 16.3 0.9 1 23 1050 1072 1050 1072 0.98
18 26 0.028 2 9.2 0.0 2 21 1099 1118 1098 1119 0.94
19 26 0.014 0.98 10.1 4.3 1 23 1164 1187 1164 1187 0.96
20 26 0.0086 0.62 10.8 1.0 1 23 1224 1247 1224 1247 0.96
21 26 0.015 1.1 10.0 3.1 1 23 1275 1298 1275 1298 0.97
22 26 1.4e-05 0.001 19.5 0.1 2 23 1326 1347 1325 1347 0.95
23 26 4.8e-05 0.0035 17.8 2.9 1 23 1353 1375 1353 1375 0.99
24 26 2.4e-06 0.00017 22.0 2.0 1 23 1381 1403 1381 1403 0.97
25 26 6e-08 4.3e-06 27.0 2.4 1 23 1409 1431 1409 1431 0.99
26 26 0.00018 0.013 16.0 0.5 1 23 1437 1459 1437 1459 0.97

Sequence Information

Coding Sequence
ATGTTGCCGACAGATATTTGCCGTACATGCACGCAACATGATGATAGCTTGCTGCCGCTTGCGACCCGCACtgataaatatgcaaataaaagtTTAAATGACATTTTACTCGAATTAACTCAAAATGATCCCCTGCAGGAGCATACGGATGATAGCCTGCCGCAGCACTTGTGTATCACTTGCTTGCACAAGTTGGAGGCTGCGTATGCGTTTGTGCTGCAGGCGCGCCAGGCTCAagagcaattgttgttgcagctgcgcAAGTGCTTGCAGACACAATGCTTGGATGAGATGCCAATAGACATTAACTTGCAGCACATCAAAACCGAAACGATCGTTGACGTGCAACTGACTAGCAAAGCTAAGAGTGAAGAAGATGCGGCGGAGGCTGAAGAGATGGCAGTGTCAGTGTCTATTCCAGTTCTGAAGTGGCAGCCAGAAAGCGATAGTGAGAGCAATCAGACTGATGTTGATGACCGGGACGTGGACTTTAAACCCAAGAAGTTACGGCGCAGCACACGTAAAGCCAAAGCCGGATCGGACAGCGAATTAGCAGCAACATCTGGTCATTCCAATGCCCTGCCTATCAAACGGCGGCGTGGTCGCCCAGCACGTCGACTCGAAAAGGAAACTATCAACGAAGACGGACGGCATGTGTGCGAGGTTTGTGGCAAGACCTTTTCGTGGTATCGCGATATGCAACGCCACTCGCGCATCCACTTTGAACAAGCGACCTTCGTGTGTGACAGTTGTGGCAAGAGTTTCCTGCGTAAAGACAAATACATGTTTCATCTGCGTTCGCACGAAAAGCGAGCAGCCAAGAGTCAGGCCATGCAACTGAGCAGCGAATGGCGTTTCGCTGAACGCCTCTACAGCTCCGGTCGGCTCAAACGAGCGGAATGTAAGCTGTGCGGCTTAAAATACCAGCGTATAGGGGAGCTGCGCGAGCATCTAGCGTGCCATAAGAGCATTGAGACTTTGTCCAAACTGAGTCTAGAGAGTGATGTTATCAGGGAACAGTTTGCCAAAGAACAGCAGCAGTTAGACTTGGCGCTAATCAAGCAAGAGCTGTGTACAGACATTGCCAAAGGACGTGGTCAGCTGGACAAATACTGCGCCGTGGTCAACGCGTACGGCTATGAGCTCTGTCTTAGCGACTCAGACGAAGAGATAGCTGAGCGATCGCCTGCATACCAGTGCCTGTCGTGTAACATCAACTTCACGCGTAAATACCGTCTAATGCGGCACACCTTGGACGAGCATACACAGCCGGAACGAGCGGTGTCTTGGCAACGCTGTGATGTTTGCcaaattggttttgtgtgtgctAATATGTTTAAGCAGCACCAACGTACGCAGTGCCACAACAAACTGAAGCGTTACAACTGTCCCAACTGCCCAGGTAAATTTATTTGGCTGCAGAACCTGGAGCAGCATGCGTGCCCGCAACGTATGAAGCAGCATGATgagcaacggcagcaaaaGCAGTGTTGTCTATGTGATATCCAATTGAACAGCATGTTCGAATTACGCGCCCATTTGCTAACCCATCAAGATGGACATAGCGGCATACATCCAGAGCAGCAAGCAACTTTCTTTCGCACCTACTATCCCAATGGCCTTGACTGCAGCTTGCTTGAGCTCAGCGCACGAATTGCCGCCGATTTTAAGGCGGAGGATTATGGGCGTTTCTTTAATGCCAGTACGAGAAACGGTGAGGAGCTCGATTTCTATGCCTCTGACTCCGATTTGAGTGACGTGGACCAGTTGAGTTCTGGCGGTACACTACACATATGTTCTCTGTGTGGCGAGACGAAAACGCGTCTGAGTCAATTGCTCGAGCATCAGCAAAGCCAGCATAGTGAGGTGCCAGAGAGACTGCCATACGTCTGTGATGATTGCGATTTGAGTTTTGTCGCTAATTCGCTGCTCCAACAGCATCGCCGACGCGTCTGTGCCAAACAGTATGCCAAGTACGAATGCCAGCAATGCAGTCAGCGCTTTTACTGGCTTTCCAATTACGAGCTGCATATGCTCCAGCAACACGAGTCTCAAGCCGAGTTGCAGACGGATGTTGTCGATGAACAGGACCGGCAGTCAAGGATGGGAAGCAAGCGCCAGTCTACAGCTTCCAAGTTACAGTGTGGCGAGTGCGAAAAGGTGTTCATCTGGCCCAAGGATCTGACGCGTCACAAGCGCCTACACCAGCCACAGGCTTTGGCACAGTACCAATGCTTGCACTGTGACCGCAAGTTCCATCGCAAGGATGGGCTTAAGTCGCATATGCGCGTGCATAGTGAACAACAAGCGGATGCATCGATTGCCAATGAACAAGCTCCCTCCATGCTGCAGCGCATGCCAGTGGTGCTGACCCAACTGTGTCGACCTAATGGCTGCAAGCAAATTCAATGCATGATATGTCTGTCGCAGCATACCAAGATATCTGATCTGCGCACGCATTTGCTTAATCATCAGCATTCGGTCAAATTTATAGAGGAGCGAAGTCAACCGGAAAGCATAGCGGGCATTTCGCGTTCTCTATATCCAGAACTAGACGCACcattggagcagcagcaattaaTCGAACGCATTCAAAATGATGTAGCAAAAAGCGTGGAGCTTGAGAGATTCATATCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGACAGCAGCGAAACGGAATCCGACTCAGACTCTGCTGAGGCAGTCAGAAGCAACAACGGGCAACTGTATAGCTGTGAACTATGCCAGGTGAAAGTATCGCGCAAGCATCAACTCTACGCCCATGAGCTGGAGCAGCATTCGTGGCAGCAGGCAACTCGTGTGTGTAACTACTGCCAGGCGAGGTTCGTAAATGAGCAGCTACTCGAGCATCACTATCGAACGCTCTGTCGCAACGTGCACCGACGTTTCTTTTGTCGTAAATGTCCGCTACGTTTCCGCTGGCGCGAGAATCTGAAGCTGCACTCGGACGTAGCACACAGTGAAACCAGAGGGGAGCAATCAAACTTGAGTATTAAGTTAAACGGGACGCCCTTGTTACCCATCGTTAGTTACGACTGCTCCGAATGCAATCGTAGCTTTAAGATGCAAAAGGATCTCACCAGGCACACTCTGATGCATGCCCAGGAGTCAAACATTTATCGCTGTCGCTGGTGTGCACGACGTTTCTATCGCCAGGCCAATCTACTTCAGCACATTGAGCGTCACGGCATTAGCGCCGAGCAGCTGCCCTATGCTGAGGCACTGCTGAATGCCAGTCGTCATCCGCATGGTCAGAAGGTTATCCAGTGTAAGGTGTGTAACGTGACCTACCCCACCATTGCAGCGCTGCGCAGCCATCTTCAATCAGCTCCAGCAGGCACACACCATGAGTTTGGCTCGCTGCTGAACTACTCTATTACCAATCAGTTGGGATACGAGCTGCACTTGGAAGACTCGGAAACGGACGAGGAGACTAAGCCACCAGGCACGCCCGCGCACTACACCTGTAGCATATGCCAACTGCGCTGTGTGCGTAAGTTTGagctgcatcagcatcagcaagCGATGCATCGACTGGAACGCATAAACGAGGGCTGTGATGCCTGCATCTTTAAGAGTGTCTCAGCAGATCTTATTAGCTATCATCGACGCGTCTTGTGCAATAACACGGAGAAACACTTCAAATGCTCCAAGTGTGGCTACAAGTTTATGTGGGAAACGAATCTCTTGCAGCACATCCAGCTGCAGCATCCAAGCAGCGAAAGTAGCGAAACGCAGCAGGATTCAAGTTCTTTGTCTGCACAGAAGGTACCCAGTGTAGAGGGCCAGATATTTCAGTGCGGCCAGTGCCCTAGTAAATATAATCGCAAAGATCGCCTGACAGCACACGTCAAGAAATGTCATGCAGCGGAAGCAAGTGGCCTCACAGCTGGGGCAGCGAAGCTTCTGAAGAACTCAACTGGCGCCAAGCAGCAGAAGAGTTTTCTTTGCGCTTTCTGCGGCAAGGCGGTTAGTTCCTCTTCCAATCTGATTATACACATACGTCGCCATACTGGTGAGAAACCTTTTAAGTGTGACTACTGCGACATGGCTTTTCCACGTTCCTCCGATCTGCAGTGCCATCGACGCACCCACACGGGCGAACGGCCGCACGTTTGCACCGTTTGCCAGAAGGGCTTTGCCCGATCGTACAAGCTGCAGCAACACATGCGCATCCACAACGGCGAACGACCATATAAGTGTACCTATTGCGACAAGAGTTTTACTCAGTCAAATGATTTGACACTTCACATACGAAGACACACGGGCGAGCGTCCCTATCAGTGCAATACGTGTGGCGAACGTTTCATTCAGGGCACAGCCCTGAAGAATCATCGCCTGCAACATGGACATCACGATGCGGCGGAAGTGGACCAGGTCAAAGATAACTAA
Protein Sequence
MLPTDICRTCTQHDDSLLPLATRTDKYANKSLNDILLELTQNDPLQEHTDDSLPQHLCITCLHKLEAAYAFVLQARQAQEQLLLQLRKCLQTQCLDEMPIDINLQHIKTETIVDVQLTSKAKSEEDAAEAEEMAVSVSIPVLKWQPESDSESNQTDVDDRDVDFKPKKLRRSTRKAKAGSDSELAATSGHSNALPIKRRRGRPARRLEKETINEDGRHVCEVCGKTFSWYRDMQRHSRIHFEQATFVCDSCGKSFLRKDKYMFHLRSHEKRAAKSQAMQLSSEWRFAERLYSSGRLKRAECKLCGLKYQRIGELREHLACHKSIETLSKLSLESDVIREQFAKEQQQLDLALIKQELCTDIAKGRGQLDKYCAVVNAYGYELCLSDSDEEIAERSPAYQCLSCNINFTRKYRLMRHTLDEHTQPERAVSWQRCDVCQIGFVCANMFKQHQRTQCHNKLKRYNCPNCPGKFIWLQNLEQHACPQRMKQHDEQRQQKQCCLCDIQLNSMFELRAHLLTHQDGHSGIHPEQQATFFRTYYPNGLDCSLLELSARIAADFKAEDYGRFFNASTRNGEELDFYASDSDLSDVDQLSSGGTLHICSLCGETKTRLSQLLEHQQSQHSEVPERLPYVCDDCDLSFVANSLLQQHRRRVCAKQYAKYECQQCSQRFYWLSNYELHMLQQHESQAELQTDVVDEQDRQSRMGSKRQSTASKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYQCLHCDRKFHRKDGLKSHMRVHSEQQADASIANEQAPSMLQRMPVVLTQLCRPNGCKQIQCMICLSQHTKISDLRTHLLNHQHSVKFIEERSQPESIAGISRSLYPELDAPLEQQQLIERIQNDVAKSVELERFISITNEAGIELSLDSSETESDSDSAEAVRSNNGQLYSCELCQVKVSRKHQLYAHELEQHSWQQATRVCNYCQARFVNEQLLEHHYRTLCRNVHRRFFCRKCPLRFRWRENLKLHSDVAHSETRGEQSNLSIKLNGTPLLPIVSYDCSECNRSFKMQKDLTRHTLMHAQESNIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKVIQCKVCNVTYPTIAALRSHLQSAPAGTHHEFGSLLNYSITNQLGYELHLEDSETDEETKPPGTPAHYTCSICQLRCVRKFELHQHQQAMHRLERINEGCDACIFKSVSADLISYHRRVLCNNTEKHFKCSKCGYKFMWETNLLQHIQLQHPSSESSETQQDSSSLSAQKVPSVEGQIFQCGQCPSKYNRKDRLTAHVKKCHAAEASGLTAGAAKLLKNSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHHDAAEVDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509945;
90% Identity
-
80% Identity
-