Basic Information

Insect: Drosophila neutralis
Gene Symbol: Glis3
Assembly: GCA_035044385.1
Location: JAWNME010000070.1:2359793-2364540[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 9.2 6.3e+02 1.3 2.4 3 23 424 447 422 447 0.89

2 5 0.2 14 6.5 0.4 1 23 456 483 456 483 0.88

3 5 1e-06 7e-05 23.2 0.5 2 23 490 513 489 513 0.97

4 5 0.001 0.069 13.7 0.8 3 23 521 543 519 543 0.92

5 5 4.1e-05 0.0028 18.1 0.4 1 23 549 573 549 573 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	9.2	6.3e+02	1.3	2.4	3	23	424	447	422	447	0.89
2	5	0.2	14	6.5	0.4	1	23	456	483	456	483	0.88
3	5	1e-06	7e-05	23.2	0.5	2	23	490	513	489	513	0.97
4	5	0.001	0.069	13.7	0.8	3	23	521	543	519	543	0.92
5	5	4.1e-05	0.0028	18.1	0.4	1	23	549	573	549	573	0.94

Sequence Information

Coding Sequence: ATGTCTTCCACaatgaagcaacagcaactgccacTATCCATTCCCAATCACAGTGCAGAgatgtttgccaaaaataaatcatacaATGAGAATGTTTGCTATGATGCATTCATGTCGCCACCATTAAGTGCCAGTGTTGGCAAGGGACACGCTGATTATCAGGAGCCCAAATCCACATTCAACAATAATACGCATTTCACATGCGCCGAACTGCAGTTTCCGGATTTTTCACATCTGTGCTTCGCAACGGAGACGCCCAACTCGGTGTTTAGTGACTATAACAGCTATACGGGACAGGAACAGGATAGGGATAGGGATgatgttgtgtgtgctgccGCGGCGCAAACGGGTATGCCCTATCAGCAGGGTCAGTACACGCAGCTGAATCGCGAGGATGTCTTTCGCTTCGAGCCGGAGGACATTGCGCGACTAACGGCCGACAATGGTTGTGGTGGAGCCTTCGCTGAATCGATCGATGGCTTAATGCAGGTGCCACAAACACCATTCACGCCGTGCAGTGGGCCGAGCGGGTGTCAATTGGGTGCCATGCCCGCACAGGTTGTCGAGCCGGTCGAGTCTCTCAATCAGGACATTGATTACTTTAATTATGATGAAGTTAATTGCCaatcaaaaaatcaatcaCCCTGCTCGTCGCCACATTTGGACGCCTGGTTGAACTTTAACCTCAGCGAAATATCGCCGGCGGACACGGTGCGCGTATCCTCACCGaaattatgcaacatttaCGAACAACTGGCGCATATTAAAGtggaacacacacagcaaaagcTGCCATCAATGAACTCCACTTTTGGCACACCCAAGTGTACACCTGTGTGTGGCAGTTACGGCGATTACTCCAATCTGTACAATAATCAAAGTGTTTACGGAAATTTAAATCCATACGCAACGGACCACTTTCAAAATAACATCTCACAAGCCATTGAGAAACCGAATCGGGAACACAAAGTTATTTGGACAATTGATGAGTTGGATGAACTAAATGCTGCCCTGGTGCTCAGCGATCCGGCTCAGCAGAGCTGCGAGTCCAAATTTGATAAGTCGGATTTCGCGTTGGACAATCTGCCAGCTGCAACGGTTGAAACCTTAAGCGATGAGCATCACTTGACGGCCAACATCAGTGACGATGACAATGACAGGGATGAGGATGACATTGACGATGTGTTTGCAGCACCCGCCGAATTGGAGAGGCGACCGGAATATGCCGATTCCATTGATGGTGAGATGGAGCAGCCCGGTTCGCTTATTTGCCACTGGTCCGAGTGCAACATGGAGTTCGCCcatcagcaaatatttgtggagCACATCGAAAAGTGTCACGTGGATGTGCGCAAGGGTGAGGATTTCTCCTGCTTCTGGCTGGACTGCCCCAGACGCTACAAGCCATTCAATGCCCGCTACAAGCTACTCATCCACATGCGCGTCCACAGCGGCGAGAAGCCCAATAAGTGTCCGTTTCCGGAATGCAATAAGGCATTTTCACGTCtggaaaatttgaaaattcatCAACGCTCGCACACAGGCGAACGGCCTTATGGCTGTCAATATAAGGGTTGCCTCAAAGCGTTCAGCAATAGCTCGGATCGTGCAAAACATCAAAGAACCCACTACGATACGAAACCCTACGCCTGCCAGCTGCCTGGCTGCACCAAACGGTACACGGACCCCTCAAGCCTGCGTAAACATGTCAAAAATCACGGACTTATGCGCCGCAAATCTGCCAGCGGTGGCGCCACAGCCACGCCCTGCAGCAAAAAGTCGGGCAAGACACGCCGCCATTCCGAATCGTCAGCATTATCAACAAGGGGACCTTCGGGTGGTGCACGCGTCGAGCAGCGCACACAGCGCAGCAGTAGTTGCAGCGAGGCAGCGCATTTGATCCAATTGGTGGGTGGTGGCCAGGATGGGGATATGCTAACGAGGGGAGCGGTGGCATCAACAACTCCGTCAACAACAGACCGCAACTATGTCTGCAGCAATGAGAATGTTGCAACTAATaacaattcaataaaatttaatgagtTGTCAAATTGCATTGTCATCATTgagcaaaaccaaaacgaggcgacaccaacagcaactgccacaacaacaacaacaactggctgTCAGGACAATAGATACAACACGACAattgcagcggcaacaacataTGACGGACTTAACTACTACAACAGCCATCGCGTTGGTGTAGGTGAGAATgtcaataatatatttgccgTAACGGAAACGGATACGTTAAGCACTTgtagcagcagcgccagcaatagcaacaattacaaaaccaGCAATCAGGACAGCTgcaataatgataatattcataaatttaatgatCTGGAACAGTTGCTATGCTCAACAACAACGGAACAACACAATTTGAACACTGATttcaatgcaacaacaacggacaATAAGTGTCAATTGAATGAGTTTGTCTCATTCGAATATGTGCGAAAGTATCTAACGGATGCATTCGAGTCAACCACCGGAGAGCAGCGACCAAAGAGCCCAGCCACAAATTCTCAGATCATTAATGATTTCGAAAATTatgatattcaatttatttga
Protein Sequence: MSSTMKQQQLPLSIPNHSAEMFAKNKSYNENVCYDAFMSPPLSASVGKGHADYQEPKSTFNNNTHFTCAELQFPDFSHLCFATETPNSVFSDYNSYTGQEQDRDRDDVVCAAAAQTGMPYQQGQYTQLNREDVFRFEPEDIARLTADNGCGGAFAESIDGLMQVPQTPFTPCSGPSGCQLGAMPAQVVEPVESLNQDIDYFNYDEVNCQSKNQSPCSSPHLDAWLNFNLSEISPADTVRVSSPKLCNIYEQLAHIKVEHTQQKLPSMNSTFGTPKCTPVCGSYGDYSNLYNNQSVYGNLNPYATDHFQNNISQAIEKPNREHKVIWTIDELDELNAALVLSDPAQQSCESKFDKSDFALDNLPAATVETLSDEHHLTANISDDDNDRDEDDIDDVFAAPAELERRPEYADSIDGEMEQPGSLICHWSECNMEFAHQQIFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPECNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHGLMRRKSASGGATATPCSKKSGKTRRHSESSALSTRGPSGGARVEQRTQRSSSCSEAAHLIQLVGGGQDGDMLTRGAVASTTPSTTDRNYVCSNENVATNNNSIKFNELSNCIVIIEQNQNEATPTATATTTTTTGCQDNRYNTTIAAATTYDGLNYYNSHRVGVGENVNNIFAVTETDTLSTCSSSASNSNNYKTSNQDSCNNDNIHKFNDLEQLLCSTTTEQHNLNTDFNATTTDNKCQLNEFVSFEYVRKYLTDAFESTTGEQRPKSPATNSQIINDFENYDIQFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567118;
90% Identity: iTF_00495440;
80% Identity: -