Basic Information

Insect: Drosophila neutralis
Gene Symbol: -
Assembly: GCA_035044385.1
Location: JAWNME010000381.1:3326134-3328880[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.5 1e+02 3.8 0.8 1 23 213 236 213 236 0.95

2 9 0.011 0.73 10.5 0.2 2 23 292 314 291 314 0.93

3 9 0.003 0.21 12.3 4.2 1 23 555 577 555 577 0.97

4 9 0.011 0.75 10.5 1.1 1 23 583 605 583 605 0.97

5 9 0.0006 0.041 14.5 0.8 1 23 611 633 611 633 0.98

6 9 3.7e-07 2.5e-05 24.6 0.1 1 23 639 661 639 661 0.99

7 9 1.5e-06 0.0001 22.6 0.4 1 23 667 689 667 689 0.99

8 9 9.1e-07 6.2e-05 23.3 1.2 2 23 696 717 695 717 0.97

9 9 0.00012 0.0083 16.6 0.7 1 23 723 746 723 746 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.5	1e+02	3.8	0.8	1	23	213	236	213	236	0.95
2	9	0.011	0.73	10.5	0.2	2	23	292	314	291	314	0.93
3	9	0.003	0.21	12.3	4.2	1	23	555	577	555	577	0.97
4	9	0.011	0.75	10.5	1.1	1	23	583	605	583	605	0.97
5	9	0.0006	0.041	14.5	0.8	1	23	611	633	611	633	0.98
6	9	3.7e-07	2.5e-05	24.6	0.1	1	23	639	661	639	661	0.99
7	9	1.5e-06	0.0001	22.6	0.4	1	23	667	689	667	689	0.99
8	9	9.1e-07	6.2e-05	23.3	1.2	2	23	696	717	695	717	0.97
9	9	0.00012	0.0083	16.6	0.7	1	23	723	746	723	746	0.96

Sequence Information

Coding Sequence: ATGCTGAAAATGACAAATGTGCCGTTGCCGAAAATGCTTaaattcagcagcagcagcagcagcggcaaaaacagcgcagcagcagcgaaaaagACTCGGCATAGTGGATTAGCAGCCGTCGCAGCTGCGTCGCTGCGCTGCGCAGTCGACGACACGGACGAATCCGATGGGGATTCTGAATCCGAACTGGATATCGAAGAGGTTCatgatgccgatgccgatgccgatgatgatgatgatgatgaagacgatgatgatgatgaggttGTGCTGCAGATCGACAGCGAGGACGAGGCTGAGTTGGAGGCACAACGCATACGCATGGATGAtataaaagcagcagcagccgccgccgccgccgcagcagaGACGCAGGTCAGTAACGGTAAAGTGAGAACGGCATCGCGCAAGCCGCGTGGGCGTCCGCCGggcagcacaaacaaaaacaacaacacaaacaacaacaagaatcggaaccagaaccagaaccagcgaaacaaaaacaaacgcaaataCTCAAAGAGCAGCTGCGCAGtcgtcgctgccgctgctgccccCGCTCCCATCTCAGCCACTGCTCCCTCTtcgattgctgctgccaaaataCATGCGGATGAGAAAACGCATCGTCTGATTTACAGTTGCGTTAAGTGCTCTCTGCTCTATGGCGATGCTCAGGCGCTCGCCCATCACTGGCACAAGGAGCACCAGTCTCGGATGAGGCAAACGTCAGTTAAACTGGAGCCACCAATCGAGCTGAGCGAAGGCCTCAAACTGACCGACTTGAAATGCTGTGCACAACTTTTGTTGCTGAGGCGCAGTGCGGATGGGGACGAGAATGAGGATCAGGAAGAgagggagcagcagcagctgcagtgcTCCACTTGCGATGCACAATTTGAGCAAGGCAAGCAGCTGCAGGCGCATCTCAGCGAGCAGCATGGCATCTTCATGCTGTTGGTGCCCAAGCAGGAGCCCAGCGAACCCATGGTCAGCATTCCATGTAATGTGGCCAGCAGTAAGTCATTACCGGTGCCGGCACTGGAGCTGCCAGAGACGCCGCCGCCAGAGAAGGAGACGGCGGATAAAGATGATCTCGCAATGATTAGTGATATGGTGGCGGAAATAACAGCCGAGCGTAGTCCCAAGGTCAAGAAGATGGTTATCAAGCTTCCAGTGGGTAAGCGAGGAGGACGCAAGCGCAAGATGAGTGAGAAGAAACCAAAGCAGGAACAGGAACTGGAGCAGGCGAAACAAGAGCAGCAGGCGAGTCAAAATGGCAAACGCAAGCGAGCACGCAAAGCACAAAAGCCAATTGAAGAGGAGGATAAGGAGAAGAAGGGGGAGGAGCAACAGGATGAGCAGAAAAAGGAGCAGCATGCGGAGCAAGATAAGCTGGAGGAAATCAAGACGGAAACAGAGCCGAGACGCGTGCGCAAAGCACGCCACTTTGTTGACTACGTGGTCGATGTGAAAgatgaggatgatgacgatgacgaagGCGATGAAGATAAGGAGACGGAGGCCGAATGCACAACGCCAAACAATAGCTCTACAGATGACAGCCTTGCGGCTGCCTCCTCTATCAAGCGTGAATCCTCCGAGGAATCGCAGCGCAATgtcaacggcaacggcaaaggcagcagcagcaccagcggcCAGCACACATGCAACTTTTGCAGCAAACCCTTTCAGCGTTTCTCCCGTTTGCAGGATCATCTGCGTCTGCACACCGGCGAGAAGCCGCATGTGTGTGGCCAGTGTGGACGGGCGTTCCGCCTGAAGATGCGTATGGTGGAGCACCAGATGCGCCATCGCACCGAGAAGGCATTCAAGTGCGAACTGTGCGGCCTGCCGCTGGCCACCAAACAGGACATGACGCTGCACATGCGGCATCACAAGAACGATCGCCGCTACAAGTGCGATCGGTGTGGCAAGGGATTCGTGCGCAGCTCCGATCTAGCCATACACGTGCGCGTGCACACCGGCGAGAAGCCGTACAGCTGTGACCTGTGCGGCAAGGCGTTCCGTGCCCGCCAGAATCTCATCGTGCATCGGCGCACGCATCTCGGCGACAAGCCCATCCAGTGCGAGATGTGCGACAAGCGTTTCTCCCGCAAAATCGATATGCGTGTCCACATGCGCCGGCACACGGgtGAGAAGCCGTTTATCTGCACTGCCTGTCAGCGTGGCTACTCCTCCCGTGTCAACTTGCAACGGCATCAGCAGCGCGAACATGGCGGCGATTTAACCACGGTGCCGCAATCACAGCAGCCAGTGCCAGCGAAGCCTGCAACACGTCGTCCTCGACGCGAGAAGCTGCAGGAGAAAATTGCCGCGCAGGAGAAGCTGCTGAATGAGCTGAAGCGTAGCCTCAGCACACTTACCGACATTGTCGAGGAGTCAACGCCAGCAGCTGTCGAGGAGGAGAAGCACAACATAACGGAACTGGCCGCGGCGGATGCAGGCGCTGGCACCGTGGCGCAGGTGTCGGTTACCGTCTCGATGCATGTGGAGCCGGCGAAGGGGGACGACGATGAAGAGATCACGCCGGAGAAGGAGAATGCGCTATCGAGCGGATCGGCAGCGGATGCCGCATCCGGCAATGGCAAGACGAAGGCCAACCGCAAGATAACCAGCTACTTCACCGTTGTTGGGCAGCAGGCGGAAATCTAA
Protein Sequence: MLKMTNVPLPKMLKFSSSSSSGKNSAAAAKKTRHSGLAAVAAASLRCAVDDTDESDGDSESELDIEEVHDADADADDDDDDEDDDDDEVVLQIDSEDEAELEAQRIRMDDIKAAAAAAAAAAETQVSNGKVRTASRKPRGRPPGSTNKNNNTNNNKNRNQNQNQRNKNKRKYSKSSCAVVAAAAAPAPISATAPSSIAAAKIHADEKTHRLIYSCVKCSLLYGDAQALAHHWHKEHQSRMRQTSVKLEPPIELSEGLKLTDLKCCAQLLLLRRSADGDENEDQEEREQQQLQCSTCDAQFEQGKQLQAHLSEQHGIFMLLVPKQEPSEPMVSIPCNVASSKSLPVPALELPETPPPEKETADKDDLAMISDMVAEITAERSPKVKKMVIKLPVGKRGGRKRKMSEKKPKQEQELEQAKQEQQASQNGKRKRARKAQKPIEEEDKEKKGEEQQDEQKKEQHAEQDKLEEIKTETEPRRVRKARHFVDYVVDVKDEDDDDDEGDEDKETEAECTTPNNSSTDDSLAAASSIKRESSEESQRNVNGNGKGSSSTSGQHTCNFCSKPFQRFSRLQDHLRLHTGEKPHVCGQCGRAFRLKMRMVEHQMRHRTEKAFKCELCGLPLATKQDMTLHMRHHKNDRRYKCDRCGKGFVRSSDLAIHVRVHTGEKPYSCDLCGKAFRARQNLIVHRRTHLGDKPIQCEMCDKRFSRKIDMRVHMRRHTGEKPFICTACQRGYSSRVNLQRHQQREHGGDLTTVPQSQQPVPAKPATRRPRREKLQEKIAAQEKLLNELKRSLSTLTDIVEESTPAAVEEEKHNITELAAADAGAGTVAQVSVTVSMHVEPAKGDDDEEITPEKENALSSGSAADAASGNGKTKANRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517159;
90% Identity: iTF_00498326;
80% Identity: -