Basic Information

Insect: Drosophila neutralis
Gene Symbol: Clamp
Assembly: GCA_035044385.1
Location: JAWNME010000531.1:744991-747175[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00011 0.0075 16.8 1.2 1 23 132 154 132 154 0.99

2 7 0.00021 0.014 15.9 0.7 1 23 380 402 380 402 0.97

3 7 4.7e-06 0.00032 21.1 0.1 1 23 408 430 408 430 0.99

4 7 3.1e-06 0.00021 21.6 3.2 1 23 436 458 436 458 0.99

5 7 3.4e-06 0.00023 21.5 0.3 1 23 464 486 464 486 0.98

6 7 1.5e-06 0.0001 22.6 0.4 1 23 492 514 492 514 0.98

7 7 6.5e-05 0.0044 17.5 0.1 1 23 520 542 520 542 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00011	0.0075	16.8	1.2	1	23	132	154	132	154	0.99
2	7	0.00021	0.014	15.9	0.7	1	23	380	402	380	402	0.97
3	7	4.7e-06	0.00032	21.1	0.1	1	23	408	430	408	430	0.99
4	7	3.1e-06	0.00021	21.6	3.2	1	23	436	458	436	458	0.99
5	7	3.4e-06	0.00023	21.5	0.3	1	23	464	486	464	486	0.98
6	7	1.5e-06	0.0001	22.6	0.4	1	23	492	514	492	514	0.98
7	7	6.5e-05	0.0044	17.5	0.1	1	23	520	542	520	542	0.97

Sequence Information

Coding Sequence: ATGGAAGACCTCACCAAGAACATAATATTCACAAACGCCATCAACGGCCAACCGACAACGATTCAATATCAAACAGCAGACGGCACCATCCTCAAACAACCCAAAATAGAGGGCCAGAAGGCCGATCAACAGCCCACCTTTTACTACACAACAAATGGCAATGGCGGCACGGTGAATCTGGCACAGTTGGCCACCACAGACGACAATAAGACTTGCTACATTACACAGCCAGTAGGTGGCTACAATTATGCTCTGGTCAACGGAATGCCCCTTAATCAGGGCACTGTGGGCATCGCCACTGTAGATGCACAAGGACGCATACAGATTGTCAATCAAAATAAGCCAATTGCAGCGACAATTTCACCGCTGCAAAACACAATATCGAACATAAGCTTCAAGTGTGATGTCTGTTCGGAGATGTTTCAGCATTTGGCACTGCTTAACGCTCACAAGCGGATGCACACCGATGGCTCCGATCCGCAGCAGCATAACTCACAGCAATCGAATGATGCCATCACGGTGGTCAATGCACAGGGTCTGGTGCAGACGCAAAACATTATCACCGGCAACGGACAGATGGGTCAGATACAAATCGTTGCTTCCGATTCACTGGAGCCAGTGCAACAGTCTgtcatgcagcagcagcaacagcagcagcagcaacaacaacaacagcaggcatcgcaacagcaacagcagcacgacAATTCCAAGTCGAGCAAGTGCATCAATTGCGGCACTGCCATGATGCATCAGTCGAAGCGCAAAGGTCCCAAGCAGGTACGCTGCGAGTCCTGCATGCAGGCGGAGCAGGcggcgcaacagcaacaaatatttgtggcacCCGATGGACAAATGGCGCATCCTGTACAAATCATATCAACCACACCCCAGGCGCAAGCTCAGCTTCAGCAGATTGTTGCCCAGCAAACTGGCAGCACAACTCCCAAGCGAGAACCGAGCTCATCCGGCCATCATCCGGTGAAGAAGCGCAACTCCCAACAGATGACCAAATGTCAAAAGTGCAATGGATCCGGCGTCGTTCTTATgggtcaacacacacacacacataccggCGCCAGTGGCTCCGTCAAACAAAATTCTGTCACTGTCAAGACCGAaAATCCCAGTAAACCCTTCAGCTGCAACATATGCGGCGGCCTCTTTTCACGCTACTCCAGCCTGTGGTCCCACAAGAAGCTGCACAGCGGCGAGAAGAACTATAAGTGCACCATCTGCGGGCTGGCATTTGCCAAGGCCGTCTACCTTAAGAACCATGCGCGCATACACACTGGCGAAAAGCCCTACAAATGTCAAACTTGTGGAATGCAGTTCTCGCAATCGCCGCATCTGAAGAATCACGAGCGCACGCACAGCGGCGAACGTCCGTATGTGTGCGGGGTGTGCGACAAGGGATTTGCGCGTCATGCCACTCTGTGGAATCATCGTCGCATACACACCGGCGAGAAGCCGTACAAGTGCGAAATATGCGGCTCGGCTTTTTCGCAGGCGGCACATCTGAAGAACCATGCCAAGGTGCACTCCGGCGAGAAGCCGtacaaatgtgaaatatgCTCGGCAGCGTTTGCCGATCGTTTCGCGTTGAAACGCCACCGTGGCATACATCAGAAGTATGGACAAACGGCGCCCAGGCAGCCGGCTGGTGATGGCATGGTCGTGCACAAGCAGGAGCTGCCCGACATGGATGACGATGCGCAACAGGAGGTGATAATCGGCGGCTTATAG
Protein Sequence: MEDLTKNIIFTNAINGQPTTIQYQTADGTILKQPKIEGQKADQQPTFYYTTNGNGGTVNLAQLATTDDNKTCYITQPVGGYNYALVNGMPLNQGTVGIATVDAQGRIQIVNQNKPIAATISPLQNTISNISFKCDVCSEMFQHLALLNAHKRMHTDGSDPQQHNSQQSNDAITVVNAQGLVQTQNIITGNGQMGQIQIVASDSLEPVQQSVMQQQQQQQQQQQQQQASQQQQQHDNSKSSKCINCGTAMMHQSKRKGPKQVRCESCMQAEQAAQQQQIFVAPDGQMAHPVQIISTTPQAQAQLQQIVAQQTGSTTPKREPSSSGHHPVKKRNSQQMTKCQKCNGSGVVLMGQHTHTHTGASGSVKQNSVTVKTENPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCTICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPRQPAGDGMVVHKQELPDMDDDAQQEVIIGGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537677;
90% Identity: iTF_00479637;
80% Identity: iTF_00522373;