Basic Information

Gene Symbol
-
Assembly
GCA_035044385.1
Location
JAWNME010000070.1:2766409-2769041[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0003 0.021 15.4 5.0 2 23 128 149 127 149 0.98
2 9 6.7e-07 4.6e-05 23.7 3.1 1 23 155 177 155 177 0.99
3 9 4.4e-07 3e-05 24.3 1.0 1 23 183 205 183 205 0.99
4 9 1.3e-05 0.00087 19.7 3.3 1 23 275 297 275 297 0.99
5 9 1.1e-06 7.8e-05 23.0 0.9 1 23 303 325 303 325 0.98
6 9 1.1e-06 7.2e-05 23.1 5.8 1 23 331 353 331 353 0.99
7 9 1.2e-05 0.0008 19.8 1.2 3 23 474 494 472 494 0.98
8 9 1.9e-06 0.00013 22.4 0.5 1 23 500 522 500 522 0.99
9 9 1.3e-07 8.9e-06 26.0 2.2 1 23 528 550 528 550 0.98

Sequence Information

Coding Sequence
ATGCATTTGAACCATGCGACGGCGGCGACAGCTGCGATGGCCAATTATCAGCACTATGCGCCCTCCCAGCTAGCCACGCACggcggcggaggaggaggcacTTCCGGCATCGGTCCAAATGGCCTGCAACAGCCGACGACCATAGCGAGCCTGCAACAAGGTCCTTTTGCATTGCATCAGTTGACCGCCGTGCAGGCCATTCAGCATCCCACCCATCAAGCCATGTTGCATCCGCAACATCCGCTGGTGCATCTGCTCGACATCTCGACGACAACGAACAGTGGCGGCGGCAATCATACACCCATCTCGCCAATGAAGCAGGAAGTGCAGAGCGTCATCAGTGAGGATGAGTCTGTGGTGGATGATCCGCGCAAGAAGAAACAGTGTCACGTGTGCAAGAATAAGTTTCGCCAATTGACGACGTTACGCAATCACATGAAAATCCATACGGATGAGCGTCCCTACAAGTGTAAGCACTGTGACAAGGCATTCCGCCAAATTTCGACGCTCACCAATCACGTGAAGATCCACACCGGCGAGAAGCCATTCACGTGCAACATTTGCGCCAAGGACTTCCGACAGCAGAGCACGCTCATCAATCACATCAAGACGCATAAGGCGGCTGAGTCGAGCACGCCGACGTCTTTACTCAATTATCAGCCGCCGTCCTCATCCGGCAAGCATAGCCGTAAATCGCAGTCGAATCAGATGCACAATGcctaccagcagcagcatcagcagcagcagcagcgtgtacAAATCTCAAAGACTCTATACTCGGGCACGTACAGCTCGCCACAGGCGGAGGAGCTGGTGAAGCCGTATCAGTGCAGTGTGTGCAAGCGACGATTCCCACAGTTGAGCACGCTGCATAATCACGAGCGGACGCACATCGATCCCAAGCCGTACAAGTGTGAGACATGCGACAAGTCCTTCAGCCAGCTGGCTACATTGGCCAATCACAAAAAGATCCACACTGGCGACAAACCGTATACGTGTTCCTACTGCCACATGCAGTTCCGTCAGCAGTCGACGCTCACCAATCACATGAAGACGCACACACATctagccagcagccagcagcagcagcagcagaacccAACGACAGTCACAGCCACAGTGGATCACTCAACCATGCCAGCGCCCCTTGCACCGGGCACACATCAGCTGACGAGCGGTCTACTGCCGAATCACCTGCACAGCACAACGCCCAATATACTCCAATTGGATCACCATCCGTTGCTCCACTTTCTTGATGGCAGCACAACGGTTAGCTCGGTCGTTGCATCCAAtgtggcagcggcggcggcagccgGTGTCAACACCAAAGTCGAACACTATCAGGCGGGCATTAGCGGCCGGATGAGTGTGGGCAATATCAATATGCTCAAGGGTGACAATCCGGATCGGCCGTTTGGCTGTAGCGTCTGTCGTCGTTTCTTCTCGCAGCAGAGCACCCTAGTTAATCACATTAAAACGCATACGGGCGAGAAGCCGTACAAGTGCAAGATCTGTGAGGTCAGTTTCCGGCAGGTGGCCACGCTCAACAATCACATGAAGATCCACACTGGTGAGAAGCCCTACAACTGTTCCTACTGTCCCAAGCAGTTTCGACAGAAGAGTACGCTACAGAATCATCTAAGGGTGCACACGTGCTAG
Protein Sequence
MHLNHATAATAAMANYQHYAPSQLATHGGGGGGTSGIGPNGLQQPTTIASLQQGPFALHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISTTTNSGGGNHTPISPMKQEVQSVISEDESVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPPSSSGKHSRKSQSNQMHNAYQQQHQQQQQRVQISKTLYSGTYSSPQAEELVKPYQCSVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHMKTHTHLASSQQQQQQNPTTVTATVDHSTMPAPLAPGTHQLTSGLLPNHLHSTTPNILQLDHHPLLHFLDGSTTVSSVVASNVAAAAAAGVNTKVEHYQAGISGRMSVGNINMLKGDNPDRPFGCSVCRRFFSQQSTLVNHIKTHTGEKPYKCKICEVSFRQVATLNNHMKIHTGEKPYNCSYCPKQFRQKSTLQNHLRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00901644;
90% Identity
iTF_00559629;